메뉴 건너뛰기




Volumn 84, Issue 8, 2001, Pages 1070-1075

Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations

Author keywords

Hypoxia; p53; Polarographic oxygen electrode; Predictive assay; Soft tissue sarcoma; Survival; Tumour oxygenation

Indexed keywords

PROTEIN P53;

EID: 0035917618     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.1728     Document Type: Article
Times cited : (206)

References (31)
  • 2
    • 0034282518 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible Factor 1α is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
    • Birner P, Schindl M, Obermair A, Plank C, Breltenecker G and Oberhuber G (2000) Overexpression of hypoxia-inducible Factor 1α is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 60: 4693-4696
    • (2000) Cancer Res , vol.60 , pp. 4693-4696
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Plank, C.4    Breltenecker, G.5    Oberhuber, G.6
  • 3
    • 0030022252 scopus 로고    scopus 로고
    • Tumor oxygenation predicts for the likelihood of distant metastasis in human soft tissue sarcoma
    • Brizel DM, Scully SP, Harrelson JM and Dewhirst MW (1996) Tumor oxygenation predicts for the likelihood of distant metastasis in human soft tissue sarcoma. Cancer Res 56: 941-943
    • (1996) Cancer Res , vol.56 , pp. 941-943
    • Brizel, D.M.1    Scully, S.P.2    Harrelson, J.M.3    Dewhirst, M.W.4
  • 4
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW and Dewhirst MW (1999) Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 53: 113-117
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 5
    • 0027983669 scopus 로고
    • Crystal structure of a p53 tumour suppressor-DNA complex: Understanding tumorigenic mutations
    • Cho Y, Gorina S, Jeffrey PD and Pavletich NP (1994) Crystal structure of a p53 tumour suppressor-DNA complex: understanding tumorigenic mutations. Science 265: 346-355
    • (1994) Science , vol.265 , pp. 346-355
    • Cho, Y.1    Gorina, S.2    Jeffrey, P.D.3    Pavletich, N.P.4
  • 6
    • 0033867776 scopus 로고    scopus 로고
    • Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
    • Dachs GU and Tozer GM (2000) Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation Eur J Cancer 36: 1649-1660
    • (2000) Eur J Cancer , vol.36 , pp. 1649-1660
    • Dachs, G.U.1    Tozer, G.M.2
  • 7
    • 0032516219 scopus 로고    scopus 로고
    • Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay
    • Di Como CJ and Prives C (1998) Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay. Oncogene 16: 2527-2539
    • (1998) Oncogene , vol.16 , pp. 2527-2539
    • Di Como, C.J.1    Prives, C.2
  • 8
    • 0025974326 scopus 로고
    • Keynote address: The influence of microenvironmental factors on the activity of radiation and drugs
    • Durand RE (1991) Keynote address: the influence of microenvironmental factors on the activity of radiation and drugs. Int J Radiat Oncol Biol Phys 20: 233-258
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , pp. 233-258
    • Durand, R.E.1
  • 11
    • 0030903084 scopus 로고    scopus 로고
    • Single-step DGGE-based mutation scanning of the p53 gene: Application to genetic diagnosis of colorectal cancer
    • Guldberg P, Nedergaard T, Nielsen HJ, Olsen AC, Ahrenkiel V and Zeuthen J (1997) Single-step DGGE-based mutation scanning of the p53 gene: application to genetic diagnosis of colorectal cancer. Hum Mutat 9: 348-355
    • (1997) Hum Mutat , vol.9 , pp. 348-355
    • Guldberg, P.1    Nedergaard, T.2    Nielsen, H.J.3    Olsen, A.C.4    Ahrenkiel, V.5    Zeuthen, J.6
  • 12
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U and Vaupel P (1996) Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 56: 4509-4515
    • (1996) Cancer Res , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 13
    • 0037480606 scopus 로고    scopus 로고
    • Hypoxic cervical cancers with low apoptotic index are highly aggressive
    • Hockel M, Schlenger K, Hockel S and Vaupel P (1999) Hypoxic cervical cancers with low apoptotic index are highly aggressive. Cancer Res 59: 4525-4528
    • (1999) Cancer Res , vol.59 , pp. 4525-4528
    • Hockel, M.1    Schlenger, K.2    Hockel, S.3    Vaupel, P.4
  • 14
    • 0031970946 scopus 로고    scopus 로고
    • Tumor oxygenation correlates with molecular growth determinants in breast cancer
    • Hohenberger P, Felgner C, Haensch W and Schlag PM (1998) Tumor oxygenation correlates with molecular growth determinants in breast cancer. Breast Cancer Res Treat 48: 97-106
    • (1998) Breast Cancer Res Treat , vol.48 , pp. 97-106
    • Hohenberger, P.1    Felgner, C.2    Haensch, W.3    Schlag, P.M.4
  • 15
    • 0026081656 scopus 로고
    • Histopathological grading of soft tissue tumours. Prognostic significance in a prospective study of 278 consecutive cases
    • Jensen OM, Hogh J, Ostgaard SE, Nordentoft AM and Sneppen O (1991) Histopathological grading of soft tissue tumours. Prognostic significance in a prospective study of 278 consecutive cases. J Pathol 163: 19-24
    • (1991) J Pathol , vol.163 , pp. 19-24
    • Jensen, O.M.1    Hogh, J.2    Ostgaard, S.E.3    Nordentoft, A.M.4    Sneppen, O.5
  • 16
    • 0005068173 scopus 로고    scopus 로고
    • European school of Oncology, Scientific Updates I. Elsevier Science BV: Amsterdam
    • Klijn JGM (1997) Prognostic and predictive value of p53. European school of Oncology, Scientific Updates I. Elsevier Science BV: Amsterdam
    • (1997) Prognostic and Predictive Value of p53
    • Klijn, J.G.M.1
  • 17
    • 0032585864 scopus 로고    scopus 로고
    • Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix
    • Knocke TH, Weitmann HD, Feldmann HJ, Selzer E and Potter R (1999) Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix. Radiother Oncol 53: 99-104
    • (1999) Radiother Oncol , vol.53 , pp. 99-104
    • Knocke, T.H.1    Weitmann, H.D.2    Feldmann, H.J.3    Selzer, E.4    Potter, R.5
  • 18
    • 0021276479 scopus 로고
    • Hypoxic fractions of solid tumours: Experimental techniques, methods of analysis, and a survey of excisting data
    • Moulder JE and Rockwell S (1984). Hypoxic fractions of solid tumours: experimental techniques, methods of analysis, and a survey of excisting data. Int J Radiat Oncol Phys 10: 695-712
    • (1984) Int J Radiat Oncol Phys , vol.10 , pp. 695-712
    • Moulder, J.E.1    Rockwell, S.2
  • 19
    • 0034307112 scopus 로고    scopus 로고
    • A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
    • Nordsmark M and Overgaard J (2000) A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol 57: 39-43
    • (2000) Radiother Oncol , vol.57 , pp. 39-43
    • Nordsmark, M.1    Overgaard, J.2
  • 20
    • 0028242772 scopus 로고
    • Measurement of human tumour oxygenation status by a polarographic needle electrode. An analysis of inter- and intratumour heterogeneity
    • Nordsmark M, Bentzen SM and Overgaard J (1994) Measurement of human tumour oxygenation status by a polarographic needle electrode. An analysis of inter- and intratumour heterogeneity. Acta Oncol 33: 383-389
    • (1994) Acta Oncol , vol.33 , pp. 383-389
    • Nordsmark, M.1    Bentzen, S.M.2    Overgaard, J.3
  • 21
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M and Overgaard J (1996a) Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiotherapy and Oncology 41: 31-39
    • (1996) Radiotherapy and Oncology , vol.41 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 23
    • 0030731275 scopus 로고    scopus 로고
    • Tumour oxygenation assessed by polarographic needle electrodes and bioenergetic status measured by 31P magnetic resonance spectroscopy in human soft tissue tumours
    • Nordsmark M, Keller J, Nielsen OS, Lundorf E and Overgaard J (1997) Tumour oxygenation assessed by polarographic needle electrodes and bioenergetic status measured by 31P magnetic resonance spectroscopy in human soft tissue tumours. Acta Oncol 36: 565-571
    • (1997) Acta Oncol , vol.36 , pp. 565-571
    • Nordsmark, M.1    Keller, J.2    Nielsen, O.S.3    Lundorf, E.4    Overgaard, J.5
  • 24
    • 0034307238 scopus 로고    scopus 로고
    • Repeatability and prognostic impact of the pretreatment pO2 histography in patients with advanced head and neck cancer
    • Rudat V, Vanselow B, Wollensack P, Bettscheider C, Osman-Ahmet S, Eble MJ and Dietz A (2000) Repeatability and prognostic impact of the pretreatment pO2 histography in patients with advanced head and neck cancer. Radiother Oncol 57: 31-37
    • (2000) Radiother Oncol , vol.57 , pp. 31-37
    • Rudat, V.1    Vanselow, B.2    Wollensack, P.3    Bettscheider, C.4    Osman-Ahmet, S.5    Eble, M.J.6    Dietz, A.7
  • 25
    • 0028215744 scopus 로고
    • Benign-to-malignant B 16 melanoma progression induced in two stages in vitro by exposure to hypoxia
    • Stackpole CW, Groszek L and Kalbag SS (1994) Benign-to-malignant B 16 melanoma progression induced in two stages in vitro by exposure to hypoxia. J Natl Cancer Inst 86: 361-367
    • (1994) J Natl Cancer Inst , vol.86 , pp. 361-367
    • Stackpole, C.W.1    Groszek, L.2    Kalbag, S.S.3
  • 27
    • 0034002284 scopus 로고    scopus 로고
    • Treatment outcome in advanced squamous cell carcinoma of the uterine cervix: Relationships to pretreatment tumor oxygenation and vascularization
    • Sundfor K, Lyng H, Trope CG and Rofstad EK (2000) Treatment outcome in advanced squamous cell carcinoma of the uterine cervix: relationships to pretreatment tumor oxygenation and vascularization. Radiother Oncol 54: 101-107
    • (2000) Radiother Oncol , vol.54 , pp. 101-107
    • Sundfor, K.1    Lyng, H.2    Trope, C.G.3    Rofstad, E.K.4
  • 28
  • 29
    • 0025807618 scopus 로고
    • Oxygenation of human tumors: Evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements
    • Vaupel P, Schlenger K, Knoop C and Hockel M (1991) Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. Cancer Res 51: 3316-3322
    • (1991) Cancer Res , vol.51 , pp. 3316-3322
    • Vaupel, P.1    Schlenger, K.2    Knoop, C.3    Hockel, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.