Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model

International Journal of Radiation Oncology Biology Physics

Volumn 51, Issue 3, 2001, Pages 840-848

  Walenta, Stefan ^a   Snyder, Stacey ^b   Haroon, Zishan A ^b   Braun, Rod D ^b   Amin, Khalid ^b   Brizel, David ^b   Mueller Klieser, Wolfgang ^a   Chance, Britton ^c   Dewhirst, Mark W ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Imaging bioluminescence; Metabolic gradients; Pimonidazole; Tumor hypoxia; Tumor metabolism

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOLOGICAL ORGANS; BIOLUMINESCENCE; DIFFUSION; GLUCOSE; IMAGING TECHNIQUES; METABOLISM; OXYGEN; TISSUE; TUMORS;

FASCIAL SURFACE;

METABOLITES;

ADENOSINE TRIPHOSPHATE; GLUCOSE; LACTIC ACID; OXYGEN;

AEROBIC METABOLISM; ANAEROBIC METABOLISM; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BREAST CARCINOMA; CONTROLLED STUDY; DENSITY; ENERGY; FASCIA; FRACTIONATION; HYPOXIA; IMAGING; IMMUNOHISTOCHEMISTRY; MEASUREMENT; METABOLITE; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN DIFFUSION; OXYGEN TENSION; PERFUSION; PRIORITY JOURNAL; RAT; SURFACE PROPERTY; VESSEL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL HYPOXIA; DIFFUSION CHAMBERS, CULTURE; GLUCOSE; LACTIC ACID; LUMINESCENT MEASUREMENTS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICROCIRCULATION; OXIDATION-REDUCTION; OXYGEN; RADIOBIOLOGY; RATS; RATS, INBRED F344;

EID: 0035501326     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01700-X     Document Type: Article

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