The MYST family of histone acetyltransferases

Current Topics in Microbiology and Immunology

Volumn 274, Issue , 2003, Pages 203-236

  Utley, R T ^a   Cote J ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; PROTEIN MYST; UNCLASSIFIED DRUG;

CELL NUCLEUS; CELL PROLIFERATION; CHROMATIN STRUCTURE; COMPLEX FORMATION; DROSOPHILA; ENZYME ACTIVITY; GENETIC CONSERVATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; YEAST;

EID: 0037242383     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-55747-7_8     Document Type: Review

References (146)

1. AASLAND R, GIBSON TJ, STEWART AF (1995) The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci 20:56-59
2. ADAMS CR, KAMAKAKA RT (1999) Chromatin assembly: biochemical identities and genetic redundancy. Curr Opin Genet Dev 9:185-190
3. AKHTAR A, BECKER PB (2000) Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila. Mol Cell 5:367-375
4. AKHTAR A, BECKER PB (2001) The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition. EMBO Rep 2:113-118
5. AKHTAR A, ZINK D, BECKER PB (2000) Chromodomains are protein-RNA interaction modules. Nature 407:405-409
6. ALLARD S, UTLEY RT, SAVARD J, CLARKE A, GRANT P, BRANDL CJ, PILLUS L, WORKMAN JL, CÔTÉ (1999) NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J 18: 5108-5119
7. BANNISTER AJ, ZEGERMAN P, PARTRIDGE JF, MISKA EA, THOMAS JO, ALLSHIRE RC, KOUZARIDES T (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410:120-124
8. BARLEV NA, LIU L, CHEHAB NH, MANSFIELD K, HARRIS KG, HALAZONETIS TD, BERGER SL (2001) Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell 8:1243-1254
9. BERTRAM MJ, BERUBE NG, HANG-SWANSON X, RAN Q, LEUNG JK, BRYCE S, SPURGERS K, BICK RJ, BALDINI A, NING Y, CLARK LJ, PARKINSON EK, BARRETT JC, SMITH JR, PEREIRA-SMITH OM (1999) Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. Mol Cell Biol 19:1479-1485
10. BORROW J, STANTON VP, ANDRESEN JM, BECHER R, BEHM FG, CHAGANTI RSK, CIVIN CI, DISTECHE C, DUBÉ I, FRSCHAUF AM, HORSMAN D, MITELMAN F, VOLINA S, WATMORE AE, HOUSMAN DE (1996) The translocation t(8;16) (p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nature Genet 14:33-41
11. BOUCHARD C, DITTRICH O, KIERMAIER A, DOHMANN K, MENKEL A, EILERS M, LUSCHER B (2001) Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 15:2042-2047
12. BOUDREAULT AA, CRONIER D, SELLECK W, LACOSTE N, UTLEY RT, ALLARD S, SAVARD J, GAGNÉ-HENLEY A, LANE WS, TAN S, CÔTÉ J (2002) Yeast enhancer of polycomb is a dual transcription regulator and defines Esa1-dependent acetylation of chromatin. Submitted
13. BRADY ME, OZANNE DM, GAUGHAN L, WAITE I, COOK S, NEAL DE, ROBSON CN (1999) Tip60 is a nuclear hormone receptor coactivator. J Biol Chem 274:17599-17604
14. BRAND M, YAMAMOTO K, STAUB A, TORA L (1999) Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction. J Biol Chem 274:18285-18289
15. BRAUNSTEIN M, ROSE AB, HOLMES SG, ALLIS CD, BROACH JR (1993) Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev 7:592-604
16. BROWN CE, HOWE L, SOUSA K, ALLEY SC, CARROZZA MJ, TAN S, WORKMAN JL (2001) Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit. Science 292:2333-2337
17. BROWN CE, LECHNER T, HOWE L, WORKMAN JL (2000) The many HATs of transcription coactivators. Trends Biochem Sci 25:15-19
18. BROWNELL JE, ALLIS CD (1995) An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei. Proc Natl Acad Sci USA 92:6364-6368
19. BURKE TW, COOK JG, ASANO M, NEVINS JR (2001) Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. J Biol Chem 276:15397-15408
20. CAO X, SUDHOF TC (2001) A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293:115-120
21. CARAPETI M, AGUIAR RC, GOLDMAN JM, CROSS NC (1998) A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. Blood 91:3127-3133
22. CARMEN AA, MILNE L, GRUNSTEIN M (2002) Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3. J Biol Chem 277: 4778-4781
23. CHAMPAGNE N, BERTOS NR, PELLETIER N, WANG AH, VEZMAR M, YANG Y, HENG HH, YANG XJ (1999) Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein. J Biol Chem 274:28528-28536
24. CHAMPAGNE N, PELLETIER N, YANG XJ (2001) The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase. Oncogene 20:404-409
25. CHENG SW, DAVIES KP, YUNG E, BELTRAN RJ, YU J, KALPANA GV (1999) c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat Genet 22:102-105
26. CHEUNG KJ Jr, LI G (2001) The tumor suppressor ING1: structure and function. Exp Cell Res 268:1-6
27. CHOY JS, TOBE BT, HUH JH, KRON SJ (2001) Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression. J Biol Chem 276: 43653-43662
28. CLAPIER CR, NIGHTINGALE KP, BECKER PB (2002) A critical epitope for substrate recognition by the nucleosome remodeling ATPase ISWI. Nucleic Acids Res 30:649-655
29. CLARKE AS, LOWELL JE, JACOBSON SJ, PILLUS L (1999) Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol Cell Biol 19:2515-2526
30. CORONA DF, CLAPIER CR, BECKER PB, TAMKUN JW (2002) Modulation of ISWI function by site-specific histone acetylation. EMBO Rep 3:242-247
31. COSMA MP, TANAKA T, NASMYTH K (1999) Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell 97:299-311
32. CREAVEN M, HANS F, MUTSKOV V, COL E, CARON C, DIMITROV S, KHOCHBIN S (1999) Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat. Biochemistry 38:8826-8830
33. DECHEND R, HIRANO F, LEHMANN K, HEISSMEYER V, ANSIEAU S, WULCZYN FG, SCHEIDEREIT C, LEUTZ A (1999) The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene 18:3316-3323
34. DELEU L, SHELLARD S, ALEVIZOPOULOS K, AMATI B, LAND H (2001) Recruitment of TRRAP required for oncogenic transformation by E1A. Oncogene 20:8270-8275
35. DHALLUIN C, CARLSON JE, ZENG L, HE C, AGGARWAL AK, ZHOU MM (1999) Structure and ligand of a histone acetyltransferase bromodomain. Nature 399:491-496
36. DONZE D, KAMAKAKA RT (2001) RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae. Embo J 20:520-531
37. EDMONSON DG, SMITH MM, ROTH SY (1996) Repression domain of the yeast global repressor tup1 directly interacts with histones H3 and H4. Genes Dev. 10:1247-1259
38. EHRENHOFER-MURRAY AE, RIVIER DH, RINE J (1997) The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function. Genetics 145:923-934
39. EISEN A, UTLEY RT, NOURANI A, ALLARD S, SCHMIDT P, LANE WS, LUCCHESI JC, CÔÉ J (2001) The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation. J Biol Chem 276:3484-3491
40. FRANK SR, SCHROEDER M, FERNANDEZ P, TAUBERT B (2001) Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev 15:2069-2082
41. FUCHS M, GERBER J, DRAPKIN R, SIF S, IKURA T, OGRYZKO V, LANE WS, NAKATANI Y, LIVINGSTON DM (2001) The p400 complex is an essential E1A transformation target. Cell 106:297-307
42. GALARNEAU L, NOURANI A, BOUDREAULT AA, ZHANG Y, HÉLIOT L, ALLARD S, SAVARD J, LANE WS, STILLMAN DJ, CÔTÉ J (2000) Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription. Mol Cell 5: 927-937
43. GAUGHAN L, BRADY ME, COOK S, NEAL DE, ROBSON CN (2001) Tip60 is a co-activator specific for class I nuclear hormone receptors. J Biol Chem 276:46841-46848
44. GAVARAVARAPU S, KAMINE J (2000) Tip60 inhibits activation of CREB protein by protein kinase A. Biochem Biophys Res Commun 269:758-766
45. GILDEA JJ, LOPEZ R, SHEARN A (2000) A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2. Genetics 156:645-663
46. GRANT PA, DUGGAN L, CÔTÉ J, ROBERTS SM, BROWNELL JE, CANDAU R, OHBA R, OWEN-HUGHES T, ALLIS CD, WINSTON F, BERGER SL, WORKMAN JL (1997) Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev 11:1640-1650
47. II s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94:45-53
48. GRANT PA, SCHIELTZ D, PRAY-GRANT MG, YATES III JR, WORKMAN JL, (1998b) The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol Cell 2:863-867
49. GRUNSTEIN M (1998) Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell 93:325-328
50. GU W, SZAUTER P, LUCCHESI JC (1998) Targeting of MOF, a putative histone acetyl transferase, to the X chromosome of Drosophila melanogaster. Dev Genet 22:56-64
51. GU W, WEI X, PANNUTI A, LUCCHESI JC (2000) Targeting the chromatin-remodeling MSL complex of Drosophila to its sites of action on the X chromosome requires both acetyl transferase and ATPase activities. EMBO J 19:5202-5211
52. HASSAN AH, NEELY KE, WORKMAN JL (2001) Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes. Cell 104:817-827
53. HEBBES TR, CLAYTON AL, THORNE AW, CRANE-ROBINSON C (1994) Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken b-globin chromosomal domain. EMBO J 13:1823-1830
54. HERCEG Z, HULLA W, GELL D, CUENIN C, LLEONART M, JACKSON S, WANG ZQ (2001) Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression. Nat Genet 29:206-211
55. HILFIKER A, HILFIKER-KLEINIR D, PANNUTI A, LUCCHESI JC (1997) mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila. EMBO J 16: 2054-2060
56. HLUBEK F, LOHBERG C, MEILER J, JUNG A, KIRCHNER T, BRABLETZ T (2001) Tip60 is a cell-type-specific transcriptional regulator. J Biochem (Tokyo) 129:635-641
57. HOWE L, AUSTON D, GRANT P, JOHN S, COOK RG, WORKMAN JL, PILLUS L (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15:3144-3154
58. HOWE L, BROWN CE, LECHNER T, WORKMAN JL (1999) Histone acetyltransferase complexes and their link to transcription. Crit Rev Eukaryot Gene Expr 9:231-243
59. HOWE L, KUSCH T, MUSTER N, CHATERJI R, YATES III JR, WORKMAN JL (2002) Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 histone acetyltransferase complex. Submitted
60. IIZUKA M, STILLMAN B (1999) Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J Biol Chem 274:23027-23034
61. IKURA T, OGRYZKO VV, GRIGORIEV M, GROISMAN R, WANG J, HORIKOSHI M, SCULLY R, QIN J, NAKATANI Y (2000) Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102:463-473
62. JACOBS SA, KHORASANIZADEH S (2002) Structure of HP1 Chromodomain Bound to a Lysine 9-Methylated Histone H3 Tail. Science 295:2080-2083
63. JACOBS SA, TAVERNA SD, ZHANG Y, BRIGGS SD, LI J, EISSENBERG JC, ALLIS CD, KHORASANIZADEH S (2001) Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J 20:5232-5241
64. JACOBSON RH, LADURNER AG, KING DS, TJIAN R (2000) Structure and function of a human TAFII250 double bromodomain module. Science 288:1422-1425
65. JENUWEIN T, ALLIS CD (2001) Translating the histone code. Science 293:1074-1080
66. JEPPESEN P, TURNER BM (1993) The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenic marker for gene expression. Cell 74:281-289
67. JIANG YW, STILLMAN DJ (1996) Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus. Genes Dev 10:604-619
68. JIN Y, WANG Y, JOHANSEN J, JOHANSEN KM (2000) JIL-1, a Chromosomal Kinase Implicated in Regulation of Chromatin Structure, Associates with the Male Specific Lethal (MSL) Dosage Compensation Complex. J Cell Biol 149:1005-1010
69. JOHN S, HOWE L, TAFROV ST, GRANT PA, STERNGLANZ R, WORKMAN JL (2000) The Something About Silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14:1196-1208
70. KAMINE J, ELANGOVAN B, SUBRAMANIAN T, COLEMAN D, CHINNADURAI G (1996) Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology 216:357-366
71. KAUFMAN PD, KOBAYASHI R, STILLMAN B (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-1. Genes Dev 11:245-357
72. KELLEY RL, MELLER VH, GORDADZE PR, ROMAN G, DAVIS RL, KURODA MI (1999) Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell 98:513-522
73. KITABAYASHI I, AIKAWA Y, NGUYEN LA, YOKOYAMA A, OHKI M (2001a) Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein. EMBO J 20:7184-7196
74. KITABAYASHI I, AIKAWA Y, YOKOYAMA A, HOSODA F, NAGAI M, KAKAZU N, ABE T, OHKI M (2001b) Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation. Leukemia 15:89-94
75. KREBS JE, Kuo MH, ALLIS CD, PETERSON CL (1999) Cell cycle-regulated histone acetylation required for expression of the yeast HO gene. Genes Dev 13:1412-1421
76. KUO MH, ALLIS CD (1998) Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 20:615-626
77. Kuo MH, ZHOU J JAMBECK P, CHURCHILL ME, ALLIS CD (1998) Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev 12:627-639
78. LACHNER M, O'CARROLL D, REA S, MECHTLER K, JENUWEIN T (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120
79. LE S, DAVIS C, KONOPKA JB, STERNGLANZ R (1997) Two new S-phase-specific genes from Saccharomyces cerevisiae. Yeast 13:1029-1042
80. LEE HJ, CHUN M, KANDROR KV (2001) Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling. J Biol Chem 276:16597-16600
81. LEGUBE G, LINARES LK, LEMERCIER C, SCHEFFNER M, KHOCHBIN S, TROUCHE D (2002) Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation. EMBO J. in press
82. LEUNG JK, BERUBE N, VENABLE S, AHMED S, TIMCHENKO N, PEREIRA-SMITH OM (2001) MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. J Biol Chem 276:39171-39178
83. LIN R, LEONE JW, COOK RG, ALLIS CD (1989) Antibodies specific to acetylated histones document the existence of deposition- and transcription-related histone acetylation in Tetrahymena. J Cell Biol 108:1577-1588
84. LIU Y, VIDANES G, LIN YC, MORI S, SIEDE W (2000) Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest. Mol Gen Genet 262:1132-1146
85. LOEWITH R, MEIJER M, LEES-MILLER SP, RIABOWOL K, YOUNG D (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20:3807-3816
86. LOEWITH R, SMITH JS, MEIJER M, WILLIAMS TJ, BACHMAN N, BOEKE JD, YOUNG D (2001) Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae. J Biol Chem 276:24068-24074
87. LUCCHESI JC (1998) Dosage compensation in flies and worms: the ups and downs of X-chromosome regulation. Curr Opin Genet Dev 8:179-184
88. LUGER K, MADER AW, RICHMOND RK, SARGENT DF, RICHMOND TJ (1997) Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389:251-260
89. LYMAN LM, Copps K, RASTELLI L, KELLEY RL, KURODA MI (1997) Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association. Genetics 147:1743-1753
90. MARTINEZ E, PALHAN VB, TJERNBERG A, LYMAR ES, GAMPER AM, KUNDU TK, CHAIT BT, ROEDER RG (2001) Human STAGA complex is a chromatin- acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol 21:6782-6795
91. MCMAHON SB, VAN BUSKIRK HA, DUGAN KA, COPELAND TD, COLE MD (1998) The novel ATM-related protein TRRAP is an essential cofactor for the c-myc and E2F oncoproteins. Cell 94:363-374
92. MEGEE PC, MORGAN BA, SMITH MM (1995) Histone H4 and the maintenance of genome integrity. Genes Dev 9:1716-1727
93. MEIJSING SH, EHRENHOFER-MURRAY AE (2001) The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae. Genes Dev 15:3169-3182
94. MELLER VH, RATTNER BP (2002) The roX genes encode redundant male-specific lethal transcripts required for targeting of the MSL complex. EMBO J 21:1084-1091
95. NEAL KC, PANNUTI A, SMITH ER, LUCCHESI JC (2000) A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. Biochim. Biophys Acta 1490:170-174
96. NIELSEN AL, OULAD-ABDELGHANI M, ORTIZ JA, REMBOUTSIKA E, CHAMBON P, LOSSON R (2001) Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol Cell 7:729-739
97. NIELSEN PR, NIETLISPACH D, MOTT HR, CALLAGHAN J, BANNISTER A, KOUZARIDES T, MURZIN AG, MURZINA NV, LAUE ED (2002) Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature 416:103-107
98. NIKIFOROV MA, CHANDRIANI S, PARK J, KOTENKO I, MATHEOS D, JOHNSSON A, MCMAHON SB, COLE MD (2002) TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Mol Cell Biol in press
99. NOURANI A, DOYON Y, UTLEY RT, ALLARD S, LANE WS, CÔTÉ J (2001) Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol Cell Biol 21:7629-7640
100. OHBA R, STEGER DJ, BROWNELL JE, MIZZEN CA, COOK RG, CÔTÉ J, WORKMAN JL, ALLIS CD (1999) A novel H2A/H4 nucleosomal histone acetyltransferase in Tetrahymena thermophila. Mol Cell Biol 19:2061-2068
101. OSADA S, SUTTON A, MUSTER N, BROWN CE, YATES JR, 3RD, STERNGLANZ R, WORKMAN JL (2001) The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1. Genes Dev 15:3155-3168
102. OWEN DJ, ORNAGHI P, YANG JC, LOWE N, EVANS PR, BALLARIO P, NEUHAUS D, FILETICI P, TRAVERS AA (2000) The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p. EMBO J 19:6141-6149
103. PANAGOPOULOS I, FIORETOS T, ISAKSSON M, SAMUELSSON U, BILLSTROM R, STROMBECK B, MITELMAN F, JOHANSSON B (2001) Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13). Hum Mol Genet 10: 395-404
104. PARK J, KUNJIBETTU S, MCMAHON SB, COLE MD (2001) The ATM-related domain of TRRAP is required forihistone acetyltransferase recruitment and Myc-dependent oncogenesis. Genes Dev 15:1619-1624
105. PARK J, WOOD MA, COLE MD (2002) BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation. Mol Cell Biol 22:1307-1316
106. PELLETIER N, CHAMPAGNE N, STIFANI S, YANG X-J (2002) MOZ and MORF histone acetyltransferases interact with Runt-domain transcription factor Runx2. Oncogene 21:in press
107. PRAKASH SK, VAN DEN VEYVER IB, FRANCO B, VOLTA M, BALLABIO A, ZOCHBI HY (1999) Characterization of a novel chromo domain gene in xp22.3 with homology to Drosophila msl-3. Genomics 59:77-84
108. RAN Q, PEREIRA-SMITH OM (2000) Identification of an alternatively spliced form of the tat interactive protein (Tip60), tip60(beta). Gene 258:141-146
109. REID JL, IYER VR, BROWN PO, STRUHL K (2000) Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase. Mol Cell 6:1297-1307
110. REIFSNYDER C, LOWELL J, CLARKE A, PILLUS L (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nature Genet 14:42-48
111. ROTH SY, DENU JM, ALLIS CD (2001) Histone acetyltransferases. Annu Rev Biochem 70:81-120
112. SALEH A, SCHIELTZ D, TING N, MCMAHON SB, LITCHFIELD DW, YATES III JR, LEES-MILLER SP, COLE MD, BRANDL CJ (1998) Tra1p is a component of the yeast Ada-Spt transcriptional regulatory complexes. J Biol Chem 273:26559-26565
113. SANJUAN R, MARIN I (2001) Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Mol Biol Evol 18:330-343
114. SCHULTZ DC, FRIEDMAN JR, RAUSCHER FJ, 3rd (2001) Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. Genes Dev 15:428-443
115. SCOTT EK, LEE T, LUO L (2001) enok encodes a Drosophila putative histone acetyltransferase required for mushroom body neuroblast proliferation. Curr Biol 11: 99-104
116. SHARMA M, ZARNEGAR M, LI X, LIM B, SUN Z (2000) Androgen receptor interacts with a novel MYST protein, HBO1. J Biol Chem 275:35200-35208
117. SHEN X, MIZUCUCHI G, HAMICHE A, WU C (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406:541-544
118. SHERIDAN AM, FORCE T, YOON HJ, O'LEARY E, CHOUKROUN G, TAHERI MR, BONVENTRE JV (2001) PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production. Mol Cell Biol 21:4470-4481
119. SHIMONO Y, MURAKAMI H, HASEGAWA Y, TAKAHASHI M (2000) RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions. J Biol Chem 275:39411-39419
120. SINCLAIR DA, CLEGG NJ, ANTONCHUK J, MILNE TA, STANKUNAS K, RUSE C, GRIGLIATTI TA, KASSIS JA, BROCK HW (1998) Enhancer of Polycomb is a suppressor of position-effect variegation in Drosophila melanogaster. Genetics 148:211-220
121. SLIVA D, ZHU YX, TSAI S, KAMINE J, YANG YC (1999) Tip60 interacts with human interleukin-9 receptor alpha-chain. Biochem Biophys Res Commun 263:149-155
122. SMITH ER, EISEN A, GU W, SATTAH M, PANNUTI A, ZHOU J, COOK RG, LUCCHESI JC, ALLIS CD (1998) ESA1 is a histone acetyltransferase that is essential for growth in yeast. Proc Natl Acad Sci USA 95:3561-3565
123. SMITH ER, PANNUTI A, GU W, STEURNAGEL A, COOK RG, ALLIS CD, LUCCHESI JC (2000) The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation. Mol Cell Biol 20:312-318
124. STANKUNAS K, BERGER J, RUSE C, SINCLAIR DA, RANDAZZO F, BROCK HW (1998) The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals. Development 125:4055-4066
125. STERNER DE, BERGER SL (2000) Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 64:435-459
126. STUCKENHOLZ C, KAGEYAMA Y, KURODA MI (1999) Guilt by association: non-coding RNAs, chromosome-specific proteins and dosage compensation in Drosophila. Trends Genet 15:454-458
127. TAKECHI S, NAKAYAMA T (1999) Sas3 is a histone acetyltransferase and requires a zinc finger motif. Biochem Biophys Res Commun 266:405-410
128. THOMAS T, Voss AK, CHOWDHURY K, GRUSS P (2000) Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development. Development 127:2537-2548
129. TURNER BM, BIRLEY AJ, LAVENDER J (1992) Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell 69:375-384
130. TYLER JK, ADAMS CR, CHEN SR, KOBAYASHI R, KAMAKAKA RT, KADONAGA JT (1999) The RCAF complex mediates chromatin assembly during DNA replication and repair. Nature 402:555-560
131. UTLEY RT, IKEDA K, GRANT PA, CÔTÉ J, STEGER DJ, EBERHARTER A, JOHN S, WORKMAN JL (1998) Transcriptional activators direct histone acetyltransferase complexes to nucleosomes. Nature 394:498-502
132. VASSILEV A, YAMAUCHI J, KOTANI T, PRIVES C, AVANTAGGIATI ML, QIN J, NAKATANI Y (1998) The 400 kDa subunit of the PCAF acetylase complex belongs to the ATM superfamily. Mol Cell 2:869-875
133. VAVRA KJ, ALLIS CD, GOROVSKY MA (1982) Regulation of histone acetylation in Tetrahymena macro- and micronuclei. J Biol Chem 257:2591-2598
134. VIGNALI M, HASSAN AH, NEELY KE, WORKMAN JL (2000 a) ATP-Dependent chromatin-remodeling complexes. Mol Cell Biol 20:1899-1910
135. VIGNALI M, STEGER DJ, NEELY KE, WORKMAN JL (2000b) Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes. EMBO J 19:2629-2640
136. VOGELAUER M, WU J, SUKA N, GRUNSTEIN M (2000) Global histone acetylation and deacetylation in yeast. Nature 408:495-498
137. WANG Y, ZHANG W, JIN Y, JOHANSEN J, JOHANSEN KM (2001) The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila. Cell 105:433-443
138. WEINBERGER M, TRABOLD PA, Lu M, SHARMA K, HUBERMAN JA, BURHANS WC (1999) Induction by adozelesin and hydroxyurea of origin recognition complex-dependent DNA damage and DNA replication checkpoints in Saccharomyces cerevisiae. J Biol Chem 274:35975-35984
139. WINSTON F, ALLIS CD (1999) The bromodomain: a chromatin-targeting module? Nat Struct Biol 6:601-604
140. WOOD MA, MCMAHON SB, COLE MD (2000) An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc. Mol Cell 5:321-330
141. WORKMAN JL, KINGSTON RE (1998) Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu Rev Biochem 67:545-579
142. XU EY, KIM S, REPLOGLE K, RINE J, RIVIER DH (1999a) Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae. Genetics 153:13-23
143. Xu EY, KIM S, RIVIER DH (1999b) SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae. Genetics 153:25-33
144. YAMAMOTO T, HORIKOSHI M (1997) Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60. J Biol Chem 272: 30595-30598
145. YAN Y, BARLEV NA, HALEY RH, BERGER SL, MARMORSTEIN R (2000) Crystal structure of yeast esal suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol Cell 6:1195-1205
146. ZHAO K, WANG W, RANDO OJ, XUE Y, SWIDEREK K, KUO A, CRABTREE GR (1998) Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95:625-636