Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator

Virology

Volumn 216, Issue 2, 1996, Pages 357-366

  Kamine, J ^a,b,c   Elangovan, B ^a   Subramanian, T ^a   Coleman, D ^b   Chinnadurai, G ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; TRANSACTIVATOR PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN ANALYSIS; VIRUS CELL INTERACTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RICE STRIPE VIRUS;

EID: 0029961534     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0071     Document Type: Article

References (61)

1. Alonso, A., Derse, D., and Peterlin, B. M. (1992). Human chromosome 12 is required for optimal interactions between tat and tar of human immunodeficiency virus type 1 in rodent cells. J. Virol. 66, 4617-4621.
2. Arya, S. K., Guo, C., Josephs, S. F., and Wong-Staal, F. (1985). Transactivator gene of human T-lymphotropic virus type III (HTLV-III). Science 229, 69-73.
3. Barillaria, G., Gendelman, R., Gallo, R. C., and Ensoli, B. (1993). The tat protein of human immunodeficiency virus type 1, a growth factor for aids kaposi saccoma virus and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the rgd amino acid sequence. Proc. Natl. Acad. Sci. USA 90, 7941-7945.
4. Berkhout, B., Silverman, R. H., and Jeang, K.-T. (1989). Tat trans-activates the human immunodeficiency virus through a nascent RNA target. Cell 59, 273-282.
5. Berkhout, B., Gatignol, A., Rabson, A. B., and Jeang, K.-T. (1990). Tar-independent activation of the HIV-1 Itr: Evidence that tat requires specific regions of the promoter. Cell 62, 757-767.
6. Buonaguro, L., Barillari, G., Chang, H. K., Bohan, C. A., Kao, V., Morgan, R., Gallo, R. C., and Ensoli, B. (1992). Effects of the human immunodeficiency virus type 1 tat protein on inflammatory cytokines. J. Virol. 66, 7159-7167.
7. Braddock, M., Chambers, A., Wilson, W., Esnouf, M. P., Adams, S. E., Kingsman, A. J., and Kingsman, S. M. (1989). HIV-1 tat "activates" presynthesized RNA in the nucleus. Cell 58, 269-279.
8. Breeden, L., and Nasmyth, K. (1985). Regulation of the yeast HO gene. Cold Spring Harbor Symp. Quant. Biol. 50, 643-650.
9. Cannon, P., Kim, S.-H., Ulich, C., and Kim, S. (1994). Analysis of tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2. J. Virol. 68, 1993-1997.
10. Carroll, R., and Derse, D. (1993). Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat ctg initiation codon. J. Virol. 67, 1433-1440.
11. Carroll, R., Martarano, L., and Derse, D. (1991). Identification of lentivirus tat functional domains through generation of equine infectious anemia virus/human immunodeficiency virus type 1 tat gene chimeras. J. Virol. 65, 3468-3474.
12. Carroll, R., Peterlin, B. M., and Derse, D. (1992). Inhibition of human immunodeficiency virus type 1 tat activity by coexpression of heterologous transactivators. J. Virol. 66, 2000-2007.
13. Cullen, B. (1993). Does HIV-1 tat induce a change in viral initiation rights? Cell 73, 417-420.
14. Czernik, A. J. (1991). Production of phosphorylation state specific antibodies. Methods Enzymol. 201, 264-283.
15. Desai, K., Loewenstein, P. M., and Green, M. (1991). Isolation of a cellular protein that binds to the human immunodeficiency virus tat protein and can potentiate transactivation of the viral promoter. Proc. Natl. Acad. Sci. USA 88, 8875-8879.
16. Dingwall, C., Ernberg, I., Gait, M. J., Green, M. S. M., Heaphy, S., Karn, J, Lowe, A. D., Singh, M., Skinner, M. A., and Valerio, R. (1989). Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (tar) RNA in vitro. Proc. Natl. Acad. Sci. USA 86, 6925-6929.
17. Durfee, T., Becherer, K., Chen, P.-L., Yeh, S.-H., Yang, Y., Kilburn, A. E., Lee, W.-H., and Elledge, S. (1993). The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7, 555-569.
18. Feng, S., and Holland, E. C. (1988). HIV-1 tat trans-activation requires the loop sequence within tar. Nature 334, 165-167.
19. Fields, S., and Song, O.-K. (1989). A novel genetic system to detect protein-protein interactions. Nature 340, 245-246.
20. Florkiewicz, R. Z., and Sommer, A. (1989). Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-aug codons. Proc. Natl. Acad. Sci. USA 86, 3978-3981.
21. Frankel, A. D., Bredt, D. S., and Pabo, C. O. (1988). Tat protein from human immunodeficiency virus forms a metal-linked dimer. Science 240, 70-73.
22. Fridell, R. A., Harding, L. S., Bogerd, H. P., and Cullen, B. R. (1995). Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentivirus tat proteins. Virology 209, 347-357.
23. Garcia, J. A., Harrich, D., Pearson, L., Mitsuyasu, R., and Gaynor, R. (1988). Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat. EMBO J. 7, 3143-3147.
24. Garcia, J. A., Harrich, D., Soultanakis, E., Wu, F., Mitsuyasu, R., and Gaynor, R. B. (1989). Human immunodeficiency virus type 1 LTR tata and tar region sequences required for transcriptional regulation. EMBO J. 8, 765-778.
25. Gorman, C., Moffat, L., and Howard, B. (1982). Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2, 1044-1051.
26. Hann, S. R., King, M. W., Bentley, D. L., Anderson, C. W., and Eisenman, R. N. (1988). A non-aug translational initiation in c-myc exon 1 generates an n-terminally distinct protein whose synthesis is disrupted in burkitt's lymphomas. Cell 52, 185-195.
27. Hart, C. E., Ou, C.-Y., Galphin, J. C., Moore, J., Bacheler, L. T., Wasmuth, J. J., Petteway, S. R., and Schochetman, G. (1989). Human chromosome 12 is required for elevated HIV-1 expression in human-hamster hybrid cells. Science 246, 488-491.
28. Herrmann, C. H., and Rice, A. P. (1995). Lentivirus tat proteins specifically associate with a cellular protein kinase, tak, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: Candidate for a tat cofactor. J. Virol. 69, 1612-1620.
29. Howcroft, T. K., Strebel, K., Martin, M. A., and Singer, D. S. (1993). Repression of mhc class 1 gene promoter activity by two exon tat of HIV. Science 260, 1320-1322.
30. Jeang, K.-T., Chun, R., Lin, N. H., Gatignol, A., Glabe, C. G., and Fan, H. (1993). In vitro and in vivo binding of human immunodeficiency virus type 1 tat protein and Sp1 transcription factor. J. Virol. 67, 6224-6233.
31. Jones, K. A., and Peterlin, B. M. (1994). Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63, 717-743.
32. Kaelin, W. G., Pallas, D. C., DeCaprio, J. A., Kaye, F. J., and Livingston, D. M. (1991). Identification of cellular proteins that can interact specifically with the T/E1a-binding region of the retinoblastoma gene product. Cell 64, 521-532.
33. Kamine, J., and Chinnadurai, G. (1992). Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral tat protein and cellular transcription factor Sp1. J. Virol. 66, 3932-3936.
34. Kamine, J., Subramanian, T., and Chinnadurai, G. (1991). Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 tat protein. Proc. Natl. Acad. Sci. USA 88, 8510-8514.
35. Kao, S.-Y., Calman, A. F., Luciw, P. A., and Peterlin, B. M. (1987). Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330, 489-493.
36. Kashanchi, F., Piras, G., Radonovich, M. F., Duvall, J. F., Fattaev, A., Chiang, C.-M., Roeder, R. G., and Brady, J. N. (1994). Direct interaction of human TFIID with the HIV-1 transactivator Tat. Nature 367, 295-299.
37. Kuppuswamy, M., Subramanian, T., Srinivasan, A., and Chinnadurai, G. (1989). Multiple functional domains of tat, the transactivator of HIV-1, defined by mutational analysis. Nucleic Acids Res. 17, 3551-3561.
38. Laspia, M. F., Rice, A. P., and Matthews, M. B. (1989). HIV-1 tat protein increases transcriptional initiation and stabilizes elongation. Cell 59, 283-292.
39. Ma, J., and Ptashne, M. (1987). A new class of yeast transcriptional activators. Cell 51, 113-119.
40. Madore, S. J., and Cullen, B. (1993). Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 tat function. J. Virol. 67, 3703-3711.
41. Malim, M. J., Hauber, H., Fenrick, R., and Cullen, B. R. (1989). Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. Nature 335, 181-183.
42. Muesing, M. A., Smith, D. H., and Capon, D. J. (1987). Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein. Cell 48, 691-701.
43. Nelbock, P., Dillon, P. J., Perkins, A., and Rosen, C. A. (1990). A cDNA for a protein that interacts with the human immunodeficiency virus tat transactivator. Science 248, 1650-1653.
44. Newstein, M., Stanbridge, E. J., Casey, G., and Shank, P. R. (1990). Human chromosome 12 encodes a species-specific factor which increases human immunodeficiency virus type 1 tat mediated transactivation in rodent cells. J. Virol. 64, 4565-4567.
45. Peterlin, B. M., Luciw, P. A., Barr, P. J., and Walker, M. D. (1986). Elevated levels of mRNA can account for the transactivation of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 83, 9734-9738.
46. Ratnasabapathy, R., Sheldon, M., Johal, L., and Hernandez, N. (1990). The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters. Genes Dev. 4, 2061-2074.
47. Rosen, C. A., Sodroski, J. G., and Haseltine, W. A. (1985). The location of cis-acting regulatory sequences in the human T-cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat. Cell 41, 813-823.
48. Roy, S., Delling, U., Chen, C.-H., Rosen, A., and Sonnenberg, N. (1990a). A bulge structure in HIV-1 tar RNA is required for tat binding and tat mediated trans-activation. Genes Dev. 4, 1365-1373.
49. Roy, S., Parkin, N. T., Rosen, C. A., Itovitch, J., and Sonenberg, N. (1990b). Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: Importance of base pairing, loop sequence, and bulges in the tat-responsive sequence. J. Virol. 64, 1402-1406.
50. Schiestl, R. H., and Gietz, R. D. (1989). High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16, 339-346.
51. Selby, M. J., Bain, E. S., Luciw, P. A., and Peterlin, B. M. (1989). Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-I long terminal repeat. Genes Dev. 3, 547-558.
52. Selby, M. J., and Peterlin, B. M. (1990). Transactivation of HIV-1 tat via a heterologous RNA binding protein. Cell 62, 769-777.
53. Shibuya, H., Irie, K., Ninomiya-Tsuji, J., Goebl, M., Taniguchi, T., and Matsumoto, K. (1992). New human gene encoding a positive modulator of HIV tat-mediated transactivation. Nature 357, 700-702.
54. Sodroski, J., Patarca, R., Rosen, C., Wong-Staal, F., and Haseltine, W. (1985). Location of the trans-activator region on the genome of human T-cell lymphotropic virus type III. Science 229, 74-77.
55. Southgate, C., Zapp, M. L., and Green, M. R. (1990). Activation of transcription by HIV-1 tat protein tethered to a nascent RNA through another protein. Nature 345, 640-642.
56. Southgate, C. D., and Green, M. R. (1991). The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: Implications for Tat function. Genes Dev. 5, 2496-2507.
57. Subramanian, T., D' Sa-Eipper, C., Elangovan, B., and Chinnadurai, G. (1994). The activation region of the tat protein of human immunodeficiency virus type-1 functions in yeast. Nucleic Acids Res. 22, 1496-1499.
58. Swaffield, J. C., Bromberg, J. F., and Johnston, S. A. (1992). Alterations in a yeast protein resembling HIV tat-binding protein relieve requirement for an acidic activation domain in gal4. Nature 357, 698-700.
59. Toohey, M. G., and Jones, K. A. (1989). In vitro formation of short RNA polymerase II transcripts that terminate within the HIV-1 and HIV-2 promoter-proximal downstream regions. Genes Dev. 3, 265-282.
60. Viscidi, R. P., Kumudini, M., Lederman, H. M., and Frankel, A. D. (1989). Inhibition of antigen-induced lymhocyte proliferation by tat protein from HIV-1. Science 246, 1606-1608.
61. Yu, L., Zhang, Z., Loewenstein, P. M., Desai, K., Tang, Q., Mao, D., Symington, J. S., and Green, M. (1995). Molecular cloning and characterization of a cellular protein that interacts with the human immunodeficiency virus type 1 tat transactivator and encodes a strong transcriptional activation domain. J. Virol. 69, 3007-3016.