mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila

EMBO Journal

Volumn 16, Issue 8, 1997, Pages 2054-2060

  Hilfiker, Andres ^a,c   Hilfiker Kleiner, Denise ^a,c   Pannuti, Antonio ^b,c   Lucchesi, John C ^c  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c EMORY UNIVERSITY   (United States)

Author keywords

Dosage compensation; Drosophila; Histone acetylation; Transcription

Indexed keywords

ACYLTRANSFERASE; HISTONE H4; LYSINE; TRANSACTIVATOR PROTEIN; ZINC FINGER PROTEIN;

ACETYLATION; ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; MALE; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; SEQUENCE HOMOLOGY; SOMATIC CELL; X CHROMOSOME;

ACETYLTRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; CHROMOSOME MAPPING; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; DOSAGE COMPENSATION, GENETIC; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENES, FUNGAL; GENES, INSECT; GENES, NEOPLASM; HISTONE ACETYLTRANSFERASES; HUMANS; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030891858     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.8.2054     Document Type: Article

References (43)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
2. Baker, B.S., Gorman, M. and Marin, I. (1994) Dosage compensation in Drosophila. Annu. Rev. Genet., 28, 491-521.
3. Bellini, M., Lacroix, J.C. and Gall, J.G. (1993) A putative zinc-binding protein on lampbrush chromosome loops. EMBO J., 12, 107-114.
4. Belote, J.M. and Lucchesi, J.C. (1980a) Sex determination in Drosophila melanogaster: from the X:A ratio to doublesex. Genetics, 96, 165-186.
5. Belote, J.M. and Lucchesi, J.C. (1980b) Control of X chromosome transcription by the maleless gene in Drosophila. Nature, 285, 573-575.
6. Berg, J.M. and Shi, Y. (1996) The galvanization of biology: a growing appreciation for the roles of zinc. Science, 271, 1081-1085.
7. Bone, J.R. and Kuroda, M.I. (1996) Dosage compensation regulatory proteins and the evolution of sex chromosomes in Drosophila. Genetics, 144, 705-713.
8. Bone, J.R., Lavender, J., Richman, R., Palmer, M.J., Turner, B.M. and Kuroda, M.I. (1994) Acetylated histone H4 on the male X-chromosome is associated with dosage compensation in Drosophila. Genes Dev., 8, 96-104.
9. Borrow, J.J. et al. (1996) The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nature Genet., 14, 33-41.
10. Breen, T.R. and Lucchesi, J.C. (1986) Analysis of the dosage compensation of a specific transcript in Drosophila melanogaster. Genetics, 112, 483-491.
11. Brownell, J.E. and Allis, C.D. (1996) Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. Dev., 6, 176-184.
12. Brownell, J.E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D.G., Roth, S.Y. and Allis, C.D. (1996) Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell, 84, 843-851.
13. Coon, S. L., Roseboom, P.H., Baler, R., Weller, J.L., Namboodiri, M.A.A., Koonin, E.V. and Klein, D.C. (1995) Pineal serotonin N-acetyltransferase: expression cloning and molecular analysis. Science, 270, 1681-1683.
14. Fattaey, A.R. et al. (1993) Characterization of the retinoblastoma binding proteins RBP1 and RBP2. Oncogene, 8, 3149-3156.
15. Fukunaga, A., Tanaka, A. and Oishi, A. (1975) Maleless, a recessive autosomal mutant of Drosophila melanogaster that specifically kills male zygotes. Genetics, 81, 135-141.
16. Georgakopoulos, T. and Thieros, G. (1992) Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription. EMBO J., 11, 4145-4152.
17. Henikoff, S. and Henikoff, J.G. (1992) Amino acid substitution matrices from protein blocks. Proc. Natl Acad. Sci. USA, 89, 10915-10919.
18. Hilfiker, A., Yang, Y., Hayes, D.H., Beard, C.A., Manning, J.E. and Lucchesi, J.C. (1994) Dosage compensation in Drosophila: the X-chromosomal binding of MSL-1 and MLE is dependent on Sxl activity. EMBO J., 13, 3542-3550.
19. Ish-Horowicz (1989) Preparing RNA from adult flies. In Ashburner, M. (ed.), Drosophila, A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 110-111.
20. Kamine, J., Elangovan, B., Subramanian, T., Coleman, D. and Chinnadurai, G. (1996) Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology, 216, 357-366.
21. Kelley, R.L. and Kuroda, M.I. (1995) Equality for X chromosomes. Science, 270, 1607-1610.
22. Kelley, R.L., Solovyeva, I., Lyman, L.M., Richman, R. and Kuroda, M.I. (1995) Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila. Cell, 81, 867-877.
23. Kleff, S., Andrulis, E.D., Anderson, C.W. and Sternglanz, R. (1995) Identification of a gene encoding a yeast histone H4 acetyltransferase. J. Biol. Chem., 270, 24674-24677.
24. Koonin, E.V., Zhou, S. and Lucchesi, J.C. (1995) The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res., 23, 4229-4233.
25. Lewis, E.B. and Bacher, F. (1968) Method of feeding ethyl methane sulfonate (EMS) to Drosophila males. Drosophila Info. Serv., 43, 193.
26. Lu, L., Berkey, K.A. and Casero, R.A., Jr (1996) RGFGIGS is an amino acid sequence required for acetyl coenzyme A binding and activity of human spermidine/spermine N1acetyltransferase. J. Biol. Chem., 271, 18920-18924.
27. Lucchesi, J.C., Skripsky, T. and Tax, F.E. (1982) A new male-specific lethal mutation in Drosophila melanogaster. Genetics, 100, s42.
28. Muller, H.J. (1932) Further studies on the nature and causes of gene mutations. Proc. VI Int. Congr. Genet., 1, 213-255.
29. Muller, H.J. (1950) Evidence of the precision of genetic adaptation. Harvey Lect. Ser., XLIII, 165-229.
30. Paro, R. and Hogness, D. (1991) The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl Acad. Sci. USA, 88, 263-267.
31. Pedone, P.V., Ghirlando, R., Clore, M.G., Gronenborn, A.M., Felsenfeld, G. and Omichinski, J.G. (1996) The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding. Proc. Natl Acad. Sci. USA, 93, 2822-2826.
32. Pirrotta, V. (1988) Vectors for P-element transformation in Drosophila. In Rodriguez, R.L. and Denhardt, D.T. (eds), Vectors. A Survey of Molecular Cloning Vectors and their Uses. Butterworth, Boston, MA, pp. 437-456.
33. Reddy, B.A., Kloc, M. and Etkin, L. (1991) The cloning and characterization of a maternally expressed novel zinc finger nuclear phosphoprotein (xnf7) in Xenopus laevis. Dev. Biol., 148, 107-116.
34. Reifsnyder, C., Lowell, J., Clarke, A. and Pillus, L. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyl transferases. Nature Genet., 14, 42-49.
35. Richter, L., Bone, J.R. and Kuroda, M.I. (1996) RNA-dependent association of the Drosophila maleless protein with the male X chromosome. Genes Cells, 1, 325-336.
36. Rubin, G.M. and Spradling, A.C. (1982) Genetic transformation of Drosophila with transposable element vectors. Science, 218, 348-352.
37. Schuler, G.D., Altschul, S.F. and Lipman, D.J. (1991) A workbench for multiple sequence alignment construction and analysis. Proteins Struct. Funct. Genet., 9, 180-190.
38. Steinemann, M., Steinemann, S. and Turner, B.M. (1996) Evolution of dosage compensation. Chromosome Res., 4, 185-190.
39. Turner, B.M., Birley, A.J. and Lavender, J. (1992) Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell, 69, 375-384.
40. Uchida, S., Uenoyama, T. and Oishi, K. (1981) Studies on the sex-specific lethals of Drosophila melanogaster. III. A third chromosome male-specific lethal mutant. Jpn. J. Genet., 56, 523-527.
41. Wolffe, A.P. (1996) Histone deacetylase: a regulator of transcription. Science, 272, 371-372.
42. Wolffe, A.P. and Pruss, D. (1996) Targeting chromatin disruption: transcription regulators that acetylate histones. Cell, 84, 817-819.
43. Yang, X.J., Ogryzko, V.V., Nishikawa, J.-I., Howard, B.H. and Nakatani, Y. (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature, 382, 319-324.