Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae

Genetics

Volumn 153, Issue 1, 1999, Pages 13-23

  Xu, Eugenia Y ^a   Kim, Susan ^a   Replogle, Kirstin ^a   Rine, Jasper ^b   Rivier, David H ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; ARTICLE; BINDING SITE; GENE CONTROL; GENE LOCUS; GENE MUTATION; GENE SILENCING; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TELOMERE;

AMINO ACID SEQUENCE; BINDING SITES; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENES, MATING TYPE, FUNGAL; GENETIC COMPLEMENTATION TEST; HUMANS; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; RAP1 GTP-BINDING PROTEINS; REPLICATION ORIGIN; REPRESSOR PROTEINS; RESPONSE ELEMENTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE; TRANSCRIPTION FACTORS;

EID: 0032830952     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. ABRAHAM, J., K. A. NASMYTH, J. N. STRATHERN, A. J. KLAR and J. B. HICKS, 1984 Regulation of mating-type information in yeast. Negative control requiring sequences both 5′ and .H′ to the regulated region. J. Mol. Biol. 176: 307-331.
2. AXELROD, A., and J. RINE, 1991 A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Sarcharomyces rerevisiae. Mol. Cell. Biol. 11: 1080-1091.
3. BANNISTER, A. J., and T. KOUZARIDES, 1996 The CBP co-activator is a histone acetyltransferase. Nature 384: 641-643.
4. BAUDIN, A., O. OZIER-KALOGEROPOULOS, A. DENOUEL, F. LACROUTE and C. CULLIN, 1993 A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21: 3329-3330.
5. BORROW, J., V. P. STANTON, JR., J. M. ANDRESEN, R. BECHER, F. G. BEHM et al., 1996 The translocation t(8;16)(p11;pl3) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat. Genet. 14: 33-41.
6. BRAND, A. H., L. BREEDEN, J. ABRAHAM, R. STERNGLANZ and K. NASMYTH, 1985 Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41: 41-48.
7. BRAND, A. H., G. MICKLEM and K. NASMYTH, 1987 A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell 51: 709-719.
8. BRAUNSTEIN, M., R. E. SOBEL, C. D. ALLIS, B. M. TURNER and J. R. BROACH, 1996 Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol. Cell. Biol. 16: 4349-4356.
9. BROWNELL, J. E., and C. D. ALLIS, 1996 Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. Dev. 6: 176-184.
10. BROWNELL, J. E., J. ZHOU, T. RANALLI, R. KOBAYASHI, D. G. EDMONDSON et al., 1996 Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84: 843-851.
11. BRYK, M., M. BANERJEE, M. MURPHY, K. E. KNUDSEN, D. J. GARFINKEL et al., 1997 Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11: 255-269.
12. BUCK, S. W., and D. SHORE, 1995 Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast. Genes Dev. 9: 370-384.
13. CAIRNS, B. R., 1998 Chromatin remodeling machines: similar motors, ulterior motives. Trends Biochem. Sci. 23: 20-25.
14. CAIRNS, B. R., N. L. HENRY and R. D. KORNBERG;, 1996 TFG/TAF30/ ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9. Mol. Cell. Biol. 16: 3308-3316.
15. CARAPETI, M., R. C. AGUIAR, J. M. GOLDMAN and N. C. CROSS, 1998 A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. Blood 91: 3127-3133.
16. CHIEN, C. T., S. BUCK, R. STERNOLANZ and D. SHORE, 1993 Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast. Cell 75: 531-541.
17. CLEARY, M. L., 1991 Oncogenic conversion of transcription factors by chromosomal translocations. Cell 66: 619-622.
18. CLEARY, M. L., 1992 Transcription factors in human leukaemias. Cancer Surv. 15: 89-104.
19. EHRENHOFER-MURRAY, A. E., D. H. RIVIER and J. RINE, 1997 The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function. Genetics 145: 923-934.
20. FELDMAN, J. B., J. B. HICKS and J. R. BROACH, 1984 Identification of sites required for repression of a silent mating type locus in yeast. J. Mol. Biol. 178: 815-834.
21. FOSS, M., F. J. MCNALLY, P. LAURENSON and J. RINE, 1993 Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae. Science 262: 1838-1844.
22. FOX, C. A., A. E. EHRENHOFER-MURRAY, S. Loo and J. RINE, 1997 The origin recognition complex, SIR1, and the S phase requirement for silencing. Science 276: 1547-1551.
23. GRUNSTEIN, M., 1998 Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell 93: 325-328.
24. HECHT, A., T. LAROCHE, S. STRAHL-BOLSINGKR, S. M. GASSER and M. GRUNSTEIN, 1995 Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592.
25. HECHT, A., S. STRAHL-BOLSINGER and M. GRUNSTEIN, 1996 Spreading of transcriptional represser SIR3 from telomeric heterochromatin. Nature 383: 92-96.
26. HENRY, N. L., A. M. CAMPBELL, W. J. FEAVER, D. POON, P. A. WEIL et al., 1994 TFIIF-TAF-RNA polymerase II connection. Genes Dev. 8: 2868-2878.
27. HOLSTEGE, F. C., E. G. JENNINGS, J. J. WYRICK, T. I. LEE, C. J. HENGARTNER et al., 1998 Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95: 717-728.
28. JONES, J. S., and L. PRAKASH, 1990 Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers. Yeast 6: 363-366.
29. JONES, R. S., and W. M. GELBART, 1993 The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax. Mol. Cell. Biol, 13: 6357-6366.
30. KIM, Y. J., S. BJORKLUND, Y. LI, M. H. SAYRE and R. D. KORNBERG, 1994 A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599-608.
31. KIMMERLY, W., A. BUCHMAN, R. KORNBERG and J. RINE, 1988 Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer. EMBO J. 7: 2241-2253.
32. KUO, M. H., J. ZHOU, P. JAMBECK, M. E. CHURCHILL, and C. D. ALLIS, 1998 Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev. 12: 627-639.
33. LOO, S., and J. RINE, 1994 Silencers and domains of generalized repression. Science 264: 1768-1771.
34. LOO, S., P. LAURENSON, M. Foss, A. DILLIN and J. RINE, 1995 Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae. Genetics 141: 889-902.
35. LUSTIG, A. J., 1998 Mechanisms of silencing in Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 8: 233-239.
36. MCNALLY, F. J., and J. RINE, 1991 A synthetic silencer mediates SIR-dependent functions in Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 5648-5659.
37. MIZZEN, C. A., X. J. YANG, T. KOKUBO, J. E. BROWNELL, A. J. BANNISTER et al., 1996 The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 87: 1261-1270.
38. MORETTI, P., K. FREEMAN, L. COODLY and D. SHORE, 1994 Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8: 2257-2269.
39. NAKAMURA, T., H. ALDER, Y. Gu, R. PRASAD, O. CANAANI et al., 1993 Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc. Natl. Acad. Sci. USA 90: 4631-4635.
40. NISLOW, C., E. RAY and L. PILLUS, 1997 SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Mol. Biol. Cell 8: 2421-2436.
41. RABBITTS, T. H., 1994 Chromosomal translocations in human cancer. Nature 372: 143-149.
42. REIFSNYDER, C., J. LOWELL, A. CLARKE and L. PILLUS, 1996 Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat. Genet. 14: 42-49.
43. RIVIER, D. H., J. L. EKENA and J. RINE, 1999 HMR-1 is an origin of replication and a silencer in Saccharomyces cerevisiae. Genetics 151: 521-529.
44. ROWLEY, J. D., S. RESHMI, O. SOBULO, T. MUSVEE, J. ANASTASI et al., 1997 All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders. Blood 90: 535-541.
45. RUNDLETT, S. E., A. A. CARMEN, N. SUKA, B. M. TURNER and M. GRUNSTEIN, 1998 Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature 392: 831-835.
46. SCHNITZLER, G., S. SIF and R. E. KINGSTON, 1998 Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state. Cell 94: 17-27.
47. SHORE, D., and K. NASMYTH, 1987 Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements. Cell 51: 721-732.
48. SMITH, E. R., A. EISEN, W. GU, M. SATTAH, A. PANNUTI et al., 1998 ESA1 is a histone acetyltransferase that is essential for growth in yeast. Proc. Natl. Acad. Sci. USA 95: 3561-3565.
49. SMITH, J. S., and J. D. BOEKE, 1997 An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11: 241-254.
50. SPENCER, F., S. L. GERRING, C. CONNELLY and P. HIETER, 1990 Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisae. Genetics 124: 237-249.
51. STRAHL-BOLSINGER, S., A. HECHT, K. Luo and M. GRUNSTEIN, 1997 SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11: 83-93.
52. TENEN, D. G., R. HROMAS, J. D. LICHT and D. E. ZHANG, 1997 Transcription factors, normal myeloid development, and leukemia. Blood 90: 489-519.
53. TKACHUK, D. C., S. KOHLER and M. L. CLEARY, 1992 Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71: 691-700.
54. VARGA-WEISZ, P. D., and P. B. BECKER, 1998 Chromatin-remodeling factors: machines that regulate? Curr. Opin. Cell Biol. 10: 346-353.
55. WACH, A., A. BRACHAT, R. POHLMANN and P. PHILIPPSEN, 1994 New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10: 1793-1808.
56. WARING, P. M., and M. L. CLEARY, 1997 Disruption of a homolog of trithorax by 11q23 translocations: leukemogenic and transcriptional implications. Curr. Top. Microbiol. Immunol. 220: 1-23.
57. WELCH, M. D., and D. G. DRUBIN, 1994 A nuclear protein with sequence similarity to proteins implicated in human acute leukemias is important for cellular morphogenesis and actin cytoskeletal function in Saccharomyces cerevisiae. Mol. Biol. Cell 5: 617-632.
58. WOTTON, D., and D. SHORE, 1997 A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Sarrharomyces cerevisiae. Genes Dev. 11: 748-760.
59. XU, E., S. KIM and D. H. RIVIER, 1999 SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisae. Genetics 153: 25-33.
60. YAMAMOTO, T., and M. HORIKOSHI, 1997 Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60. J. Biol. Chem. 272: 30595-30598.