Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3

EMBO Journal

Volumn 20, Issue 18, 2001, Pages 5232-5241

  Jacobs, Steven A ^a   Taverna, Sean D ^a   Zhang, Yinong ^a   Briggs, Scott D ^a   Li, Jinmei ^a   Eissenberg, Joel C ^b   Allis, C David ^a   Khorasanizadeh, Sepideh ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromo domain; Esa1; Heterochromatin associated protein 1 (HP1); Histone tail; Lysine methylation

Indexed keywords

ACYLTRANSFERASE; DNA BINDING PROTEIN; HISTONE H3; LYSINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CALORIMETRY; DROSOPHILA; ENTHALPY; GENE CONTROL; GENE SILENCING; HETEROCHROMATIN; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LARVA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYTENE CHROMOSOME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOMES; DROSOPHILA; FLUORESCENCE POLARIZATION; GENE SILENCING; HISTONES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; THERMODYNAMICS;

EID: 0035903443     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.18.5232     Document Type: Article

References (48)

1. Chromodomains are protein-RNA interaction modules
2. Structure of the chromatin binding (chromo) domain from mouse modifier protein 1
3. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
4. Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila
5. Studies of histone methylation during the HeLa S-3 cell cycle
6. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer
7. Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation
8. NMRPipe: A multidimensional spectral processing system based on UNIX PIPES
9. Structure and ligand of a histone acetyltransferase bromodomain
10. Methylated basic amino acid composition of histories from various organs from the rat
11. Position effect variegation in Drosophila: Towards genetics of chromatin assembly
12. The HPI protein family: Getting a grip on chromatin
13. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
14. The heterochromatin protein 1 prevents telomere fusions in Drosophila
15. Improved 3D triple-resonance NMR techniques applied to a 31 kDa protein
16. 2O in protein NMR. Application to sensitivity enhancement and NOE measurement
17. The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
18. Solution structure, domain features and structural implications of mutants of the chromo domain from the fission yeast histone methyltransferase Clr4
19. Solution structure and acetyl-lysine binding acitivity of the GCN5 bromodomain
20. 11250 double bromodomain module
21. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene
22. Re-SET-ting heterochromatin by histone methyltransferases
23. NMRview: A computer program for the visualization and analysis of NMR data
24. 15N inverse detected heteronuclear NMR spectroscopy: Application to staphylococcal nuclease
25. Modular peptide recognition domains in eukaryotic signaling
26. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
27. 15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: Application to interleukin 1β
28. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells
29. Signaling to chromatin through histone modifications: How clear is the signal?
30. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
31. Heterochromatin formation in mammalian cells: Interaction between histones and HP1 proteins
32. Human spleen histone H3. Isolation and amino acid sequence
33. The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
34. Functional analysis of the chromo domain of HP1
35. Regulation of chromatin structure by site-specific histone H3 methyltransferases
36. Histone methylation versus histone acetylation: New insights into epigenetic regulation
37. Position effect variegation in Drosophila
38. Acetylation of histones and transcription-related factors
39. The language of covalent histone modifications
40. Methylation of histone H3 at lysine 4 is highly conserved and correlated with transcriptionally active nuclei in Tetrahymena
41. Histone acetylation and an epigenetic code
42. Heterochromatin and gene expression in Drosophila
43. The bromodomain: A chromatin-targeting module?
44. Rapid measurement of binding constant and heats of binding using a new titration calorimeter
45. Review: Chromatin structural features and targets that regulate transcription
46. Phosphorylation site mutations in heterochromatin protein 1 (HP1) reduce or eliminate silencing activity