The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae

Genes and Development

Volumn 15, Issue 23, 2001, Pages 3169-3182

  Meijsing, S H ^a   Ehrenhofer Murray, A E ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

Acetyltransferase; Heterochromatin; Histone acetylation; PCNA; Silencing

Indexed keywords

ACYLTRANSFERASE; ARGININE; DNA; HISTONE; LYSINE; NUCLEAR PROTEIN; PROTEIN ASF1; PROTEIN CAF I; PROTEIN SAS; RIBOSOME DNA; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHROMATIN; CONTROLLED STUDY; DEACETYLATION; DNA REPLICATION; GENE EXPRESSION; GENE SILENCING; NONHUMAN; NUCLEOSOME; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE;

ACETYL COENZYME A; ACETYLATION; ACETYLTRANSFERASES; BINDING SITES; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA, FUNGAL; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENE SILENCING; HISTONE ACETYLTRANSFERASES; HISTONES; MACROMOLECULAR SUBSTANCES; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN BINDING; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; ZINC FINGERS;

SACCHAROMYCES CEREVISIAE;

EID: 0035577669     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.929001     Document Type: Article

References (42)

1. Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila
2. The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition
3. Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern
4. The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest
5. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
6. The role of Sas2, an acetyltransferase homolog of Saccharomyces cerevisiae, in silencing and ORC function
7. A role for the replication proteins PCNA, RF-C, polymerase epsilon and Cdc45 in transcriptional silencing in Saccharomyces cerevisiae
8. Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci
9. RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo
10. Localization of Sir2p: The nucleolus as a compartment for silent information regulators
11. Histone acetylation in chromatin structure and transcription
12. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
13. Disruption of the nucleosomes at the replication fork
14. Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction
15. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
16. II30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex
17. Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci
18. CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1
19. Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I
20. Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I
21. Enzymatic activities of Sir2 and chromatin silencing
22. A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae
23. Heterochromatin dynamics in mouse cells: Interaction between chromatin assembly factor I and HPI proteins
24. Yeast silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases
25. Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
26. An uncertain silence
27. Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
28. Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae
29. An unusual form of transcriptional silencing in yeast ribosomal DNA
30. A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors
31. Stepwise assembly of chromatin during DNA replication in vitro
32. Acetylation of histones and transcription-related factors
33. Chromatin assembly during SV40 DNA replication in vitro
34. Yeast Asf1 protein is required for cell cycle regulation of histone gene transcription
35. Duplication and maintenance of heterochromatin domains
36. Sas3 is a histone acetyltransferase and requires a zinc finger motif
37. A truncated form of the human CAF-1 p150 subunit impairs the maintenance of transcriptional gene silencing in mammalian cells
38. The RCAF complex mediates chromatin assembly during DNA replication and repair
39. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
40. SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae
41. Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins
42. PCNA connects DNA replication to epigenetic inheritance in yeast