Type 2 antifolates in the chemotherapy of falciparum malaria

Journal of the Brazilian Chemical Society

Volumn 13, Issue 6, 2002, Pages 727-741

  Delfino, Reinaldo T ^a   Santos Filho, Osvaldo A ^a,b   Figueroa Villar, José D ^a  

^a MILITARY INSTITUTE OF ENGINEERING   (Brazil)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Antifolate resistance; Dihydrofolate reductase; Malaria; Plasmodium falciparum

Indexed keywords

4,6 DIAMINO 1,2 DIHYDRO 2,2 DIMETHYL 1 [3 (2,4,5 TRICHLOROPHENOXY)PROPOXY] 1,3,5 TRIAZINE; AMODIAQUINE; ARTEMETHER; ARTEMISININ DERIVATIVE; ARTESUNATE; ATOVAQUONE PLUS PROGUANIL; CHLOROQUINE; CYCLOGUANIL; DAPSONE; DIHYDROARTEMISININ; DIHYDROFOLATE REDUCTASE; FANSIDAR; FANSIMEF; FLUOROOROTIC ACID; FOLIC ACID ANTAGONIST; HALOFANTRINE; KELFIPRIM; MEFLOQUINE; METHOTREXATE; PYRIMETHAMINE; QUINIDINE; QUININE; QUININE DERIVATIVE; SULFADIAZINE; SULFADOXINE; SULFALENE; SULFONAMIDE; SULFONE DERIVATIVE; TRIMETHOPRIM; UNINDEXED DRUG;

ANTIMALARIAL ACTIVITY; COMBINATION CHEMOTHERAPY; CONFERENCE PAPER; DRUG COST; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG RESISTANCE; DRUG SAFETY; DRUG STRUCTURE; ENZYME METABOLISM; ENZYME STRUCTURE; ENZYME SYNTHESIS; GASTROINTESTINAL SYMPTOM; HEART DISEASE; HEART VENTRICLE ARRHYTHMIA; HUMAN; IDIOPATHIC DISEASE; MALARIA CONTROL; MALARIA FALCIPARUM; MUTATION; NONHUMAN; PARASITE TRANSMISSION; PREVALENCE; TREATMENT FAILURE; TREATMENT OUTCOME; VECTOR CONTROL;

EID: 0036985310     PISSN: 01035053     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0103-50532002000600003     Document Type: Conference Paper

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