Antifolate resistance due to new and known Plasmodium falciparum dihydrofolate reductase mutations expressed in yeast

Molecular and Biochemical Parasitology

Volumn 94, Issue 2, 1998, Pages 205-214

  Cortese, Joseph F ^a   Plowe, Christopher V ^a  

^a Div Geogr Med Dept Med U   (United States)

Author keywords

Antifolate; Dihydrofolate reductase; Drug resistance; Plasmodium falciparum; Saccharomyces cerevisiae

Indexed keywords

4,6 DIAMINO 1,2 DIHYDRO 2,2 DIMETHYL 1 [3 (2,4,5 TRICHLOROPHENOXY)PROPOXY] 1,3,5 TRIAZINE; CHLORCYCLOGUANIL; CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; FANSIDAR; PYRIMETHAMINE; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; DRUG RESISTANCE; GENE EXPRESSION SYSTEM; MALARIA; MUTATION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; YEAST;

ANIMALS; ANTIMALARIALS; BOLIVIA; CHLOROGUANIDE; DNA, PROTOZOAN; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; MALARIA, FALCIPARUM; MUTATION; PLASMODIUM FALCIPARUM; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TETRAHYDROFOLATE DEHYDROGENASE; TRANSFORMATION, GENETIC;

PLASMODIUM FALCIPARUM; SACCHAROMYCES CEREVISIAE;

EID: 0032145128     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00075-9     Document Type: Article

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