Direct measurement of the pK(a) of aspartic acid 26 in Lactobacillus casei dihydrofolate reductase: Implications for the catalytic mechanism

Biochemistry

Volumn 38, Issue 25, 1999, Pages 8038-8044

  Casarotto, Marco G ^a   Basran, Jaswir ^b   Badii, Ramin ^b   Sze, Kong Hung ^c   Roberts, Gordon C K ^a  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CARBON 13; DIHYDROFOLATE REDUCTASE; 1,4,5,6 TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE; 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE; APOENZYME; DIHYDROFOLIC ACID; DRUG DERIVATIVE; FOLIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME ANALYSIS; HYDROGEN BOND; ION TRANSPORT; LACTOBACILLUS CASEI; MUTAGENESIS; POLARIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; REACTION ANALYSIS; REDUCTION; CHEMISTRY; ENZYMOLOGY; MACROMOLECULE; METABOLISM; PH;

BACTERIA (MICROORGANISMS); LACTOBACILLUS CASEI;

APOENZYMES; ASPARTIC ACID; CATALYSIS; FOLIC ACID; HYDROGEN-ION CONCENTRATION; LACTOBACILLUS CASEI; MACROMOLECULAR SUBSTANCES; NAD; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 0033594816     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990301p     Document Type: Article

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