Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR

Biophysical Chemistry

Volumn 98, Issue 3, 2002, Pages 287-300

  Delfino, Reinaldo Teixeira ^a   Santos Filho, Osvaldo Andrade ^b   Figueroa Villar, José Daniel ^a  

^a MILITARY INSTITUTE OF ENGINEERING   (Brazil)

^b Lab 609   (Brazil)

Author keywords

Antifolate resistance; Dihydrofolate reductase; Docking; Homology modeling; Malaria; Plasmodium falciparum

Indexed keywords

CYCLOGUANIL; FOLIC ACID ANTAGONIST; PYRIMETHAMINE;

ARTICLE; ENZYME INHIBITION; MALARIA; MOLECULAR MODEL; MUTATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; CHICKENS; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; HUMANS; LIVER; MALARIA, FALCIPARUM; MODELS, CHEMICAL; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POINT MUTATION; PYRIMETHAMINE; SEQUENCE ALIGNMENT; TETRAHYDROFOLATE DEHYDROGENASE; TRIAZINES;

PLASMODIUM FALCIPARUM;

EID: 0037008362     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(02)00077-7     Document Type: Article

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