Notch signaling in lymphocyte development

Current Opinion in Genetics and Development

Volumn 11, Issue 5, 2001, Pages 554-560

  Anderson, A C ^a   Robey, E A ^a   Huang, Y H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH RECEPTOR; T LYMPHOCYTE RECEPTOR;

CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL GROWTH; CELL LINEAGE; CELL MATURATION; GENE ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; LYMPHATIC LEUKEMIA; LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; T LYMPHOCYTE; THYMOMA; TRANSGENE;

EID: 0035479839     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00232-X     Document Type: Review

References (46)

1. LIN-12/Notch signaling: Lessons from worms and flies
2. Notch signaling: Cell fate control and signal integration in development
3. Notch signal transduction: A real RIP and more
4. Modulated expression of Notch 1 during thymocyte development
5. A role for Pref-1 and HES-1 in thymocyte development
6. Notch 1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells
7. Expression pattern on Notch 1, 2 and 3 and Jagged 1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T-cell development
8. Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis
9. An activated form of Notch influences the choice between CD4 and CD8 T-cell lineages
10. Notch activity influences the αβ vs. γδ T-cell lineage decision
11. Deficient T-cell fate specification in mice with an induced inactivation of Notch 1
12. Notch 1 expression in early lymphoiesis influences B versus T-lineage determination
13. Notch 1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
14. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch 1
15. Correlating Notch signaling with thymocyte maturation
16. MHC recognition in thymic development: Distinct, parallel pathways for survival and lineage commitment
17. + thymocytes by modulating TCR signal strength
18. Lck activity controls CD4/CD8 T-cell lineage commitment
19. Lck domains differentially contribute to pre-T-cell receptor (TCR) and TCR-α/β-regulated developmental transitions
20. The cytoplasmic domain of CD4 promotes the development of CD4 lineage T-cells
21. MHC class II-specific T-cells can develop in the CD8 lineage when CD4 is absent
22. The influence of the MAPK pathway on T-cell lineage commitment
23. Inducible expression of the p56lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes
24. Notch inhibtion of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development
25. + T-cell lineage fate
26. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8 T-cell development
27. Cutting edge: An essential role for Notch 1 in the development of both thymus-independent and dependent T-cells in the gut
28. Signalling downstream of activated mammalian Notch
29. Notch and the CD4 versus CD8 lineage decision
30. The notch pathway intermediate HES-1 silences CD4 gene expression
31. Negative regulation of CD4 gene expression by a HES-1-c-Myb complex
32. Subclass-specific nuclear localization of a novel CD4 silencer binding factor
33. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis
34. Notch inhibition of E47 supports the existence of a novel signaling pathway
35. The role of E-proteins in B- and T-lymphocyte development
36. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T-lymphoblastic neoplasms
37. A carboxy-terminal deletion mutant of Notch 1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice
38. Identification of Notch 1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus
39. Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5
40. Mastermind is a putative activator for Notch
41. Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch 3 transgenic mice
42. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
43. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch 1 signaling
44. Cell cycle arrest and apoptosis induced by Notch 1 in B-cells
45. Presenilin-dependent γ-secretase activity modulates thymocyte development
46. γ-Secretase inhibitors repress thymocyte development