-
6
-
-
0034234512
-
Detection of clonotypic IGH and TCR rearrangements in the neonatal blood spots of infants and children with B-cell precursor acute lymphoblastic leukemia
-
(2000)
Blood
, vol.96
, pp. 264-268
-
-
Yagi, T.1
Hibi, S.2
Tabata, Y.3
Kuriyama, K.4
Teramura, T.5
Hashida, T.6
Shimizu, Y.7
Takimoto, T.8
Todo, S.9
Sawada, T.10
Imashuku, S.11
-
7
-
-
0033372067
-
Molecular genetics, natural history and the demise of childhood leukaemia
-
(1999)
Eur J Cancer
, vol.35
, pp. 1941-1953
-
-
Greaves, M.1
-
11
-
-
0035866811
-
Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion
-
(2001)
Cancer Res
, vol.61
, pp. 2542-2546
-
-
Alexander, F.E.1
Patheal, S.L.2
Biondi, A.3
Brandalise, S.4
Cabrera, M.E.5
Chan, L.C.6
Chen, Z.7
Cimino, G.8
Cordoba, J.C.9
Gu, L.J.10
Hussein, H.11
Ishii, E.12
Kamel, A.M.13
Labra, S.14
Magalhaes, I.Q.15
Mizutani, S.16
Petridou, E.17
De Oliveira, J.L.18
Greaves, M.F.19
-
13
-
-
0033105657
-
Susceptibility to childhood acute lymphoblastic leukemia: Influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms
-
(1999)
Blood
, vol.93
, pp. 1496-1501
-
-
Krajinovic, M.1
Labuda, D.2
Richer, C.3
Karimi, S.4
Sinnett, D.5
-
14
-
-
0034730947
-
The glutathione S-transferase μ-polymorphism and susceptibility to acute lymphocytic leukemia
-
(2000)
Cancer Lett
, vol.158
, pp. 43-45
-
-
Saadat, I.1
Saadat, M.2
-
16
-
-
0031032786
-
Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia
-
(1997)
Blood
, vol.89
, pp. 1701-1707
-
-
Chen, C.L.1
Liu, Q.2
Pui, C.H.3
Rivera, G.K.4
Sandlund, J.T.5
Ribeiro, R.6
Evans, W.E.7
Relling, M.V.8
-
18
-
-
13044264463
-
Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: A report from the children's cancer group
-
(1999)
Blood
, vol.94
, pp. 4036-4045
-
-
Heerema, N.A.1
Nachman, J.B.2
Sather, H.N.3
Sensel, M.G.4
Lee, M.K.5
Hutchinson, R.6
Lange, B.J.7
Steinherz, P.G.8
Bostrom, B.9
Gaynon, P.S.10
Uckun, F.11
-
20
-
-
18244379398
-
Prognostic classification of pediatric T-ALL using oligonucleotide microarrays
-
Abs 3163
-
(2001)
Ann Meet Am Soc Hematol
-
-
Ferrando, A.A.1
Neuberg, D.2
Staunton, J.3
Huard, C.4
Raimondi, S.C.5
Behm, F.G.6
Downing, J.R.7
Gilliland, D.G.8
Golub, T.R.9
Pui, C.H.10
Lander, E.S.11
Look, A.T.12
-
26
-
-
0030934850
-
Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
-
(1997)
Ann Intern Med
, vol.126
, pp. 608-614
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
Fessing, M.Y.4
Tai, H.L.5
Pui, C.H.6
Relling, M.V.7
Evans, W.E.8
-
29
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 2001-2008
-
-
Relling, M.V.1
Hancock, M.L.2
Rivera, G.K.3
Sandlund, J.T.4
Ribeiro, R.C.5
Krynetski, E.Y.6
Pui, C.H.7
Evans, W.E.8
-
30
-
-
0035871560
-
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
-
(2001)
J Clin Oncol
, vol.19
, pp. 2293-2301
-
-
Evans, W.E.1
Hon, Y.Y.2
Bomgaars, L.3
Coutre, S.4
Holdsworth, M.5
Janco, R.6
Kalwinsky, D.7
Keller, F.8
Khatib, Z.9
Margolin, J.10
Murray, J.11
Quinn, J.12
Ravindranath, Y.13
Ritchey, K.14
Roberts, W.15
Rogers, Z.R.16
Schiff, D.17
Steuber, E.Y.18
Relling, M.V.19
-
31
-
-
0032212759
-
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathiopurine
-
(1998)
Ann Intern Med
, vol.129
, pp. 716-718
-
-
Black, A.J.1
McLeod, H.L.2
Capell, H.A.3
Powrie, R.H.4
Matowe, L.K.5
Pritchard, S.C.6
Collie-Duguid, E.S.7
Reid, D.M.8
-
32
-
-
0033376417
-
Thiopurine methyltransferase genotype and the toxicity of azathiopurine in Japanese
-
(1999)
Intern Med
, vol.38
, pp. 944-947
-
-
Ishioka, S.1
Hiyama, K.2
Sato, H.3
Yamanishi, Y.4
McLeod, H.L.5
Kumagai, K.6
Maeda, H.7
Yamakido, M.8
-
35
-
-
0033434009
-
Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals
-
(1999)
Pharmacogenetics
, vol.9
, pp. 773-776
-
-
McLeod, H.L.1
Pritchard, S.C.2
Githang'a, J.3
Indalo, A.4
Ameyaw, M.M.5
Powrie, R.H.6
Booth, L.7
Collie-Duguid, E.S.8
-
37
-
-
0030955502
-
Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: Implications for folate intake recommendations
-
(1997)
Lancet
, vol.349
, pp. 1591-1593
-
-
Molloy, A.M.1
Daly, S.2
Mills, J.L.3
Kirke, P.N.4
Whitehead, A.S.5
Ramsbottom, D.6
Conley, M.R.7
Weir, D.G.8
Scott, J.M.9
-
38
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
(1995)
Nature Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.J.7
Den Heijer, M.8
Kluijtmans, L.A.9
Van den Heuvel, L.P.10
-
39
-
-
0031936472
-
Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during long-term, low dose methotrexate therapy for rheumatoid arthritis: Implications for cardiovascular disease prevention
-
(1998)
J Rheumatol
, vol.25
, pp. 441-446
-
-
Morgan, S.L.1
Baggott, J.E.2
Lee, J.Y.3
Alarcon, G.S.4
-
40
-
-
0035412398
-
Pharmacogenetics of methotrexate: Toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
-
(2001)
Blood
, vol.98
, pp. 231-234
-
-
Ulrich, C.M.1
Yasui, Y.2
Storb, R.3
Schubert, M.M.4
Wagner, J.L.5
Bigler, J.6
Ariail, K.S.7
Keener, C.L.8
Li, S.9
Liu, H.10
Farin, F.M.11
Potter, J.D.12
-
44
-
-
0035281735
-
Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia
-
(2001)
J Clin Oncol
, vol.19
, pp. 1279-1287
-
-
Davies, S.M.1
Robison, L.L.2
Buckley, J.D.3
Tjoa, T.4
Woods, W.G.5
Radloff, G.A.6
Ross, J.A.7
Perentesis, J.P.8
-
45
-
-
0033954510
-
Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies
-
(2000)
Leukemia
, vol.14
, pp. 232-237
-
-
Woo, M.H.1
Shuster, J.J.2
Chen, C.3
Bash, R.O.4
Behm, F.G.5
Camitta, B.6
Felix, C.A.7
Kamen, B.A.8
Pui, C.H.9
Raimondi, S.C.10
Winick, N.J.11
Amylon, M.D.12
Relling, M.V.13
-
46
-
-
0035949708
-
Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11592-11597
-
-
Allan, J.M.1
Wild, C.P.2
Rollinson, S.3
Willett, E.V.4
Moorman, A.V.5
Dovey, G.J.6
Roddam, P.L.7
Roman, E.8
Cartwright, R.A.9
Morgan, G.J.10
-
48
-
-
0035479620
-
Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes
-
(2001)
Mutat Res
, vol.482
, pp. 11-19
-
-
Ingelman-Sundberg, M.1
-
49
-
-
0035071598
-
Seqeunce diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
(2001)
Nature Genet
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
Maurel, P.11
Relling, M.12
Brimer, C.13
Yasuda, K.14
Venkataramanan, R.15
Strom, S.16
Thummel, K.17
Boguski, M.S.18
Schuetz, E.19
-
50
-
-
0034702552
-
Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia
-
(2000)
Lancet
, vol.356
, pp. 285-290
-
-
Relling, M.V.1
Pui, C.H.2
Sandlund, J.T.3
Rivera, G.K.4
Hancock, M.L.5
Boyett, J.M.6
Schuetz, E.G.7
Evans, W.E.8
-
57
-
-
0027314191
-
Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: Prognostic implications
-
(1993)
Blood
, vol.81
, pp. 2394-2398
-
-
Goasguen, J.E.1
Dossot, J.M.2
Fardel, O.3
Le Mee, F.4
Le Gall, E.5
Leblay, R.6
LePrise, P.Y.7
Chaperon, J.8
Fauchet, R.9
-
58
-
-
0033040149
-
P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: Results of a 6-year prospective study
-
(1999)
Br J Haematol
, vol.105
, pp. 676-683
-
-
Dhooge, C.1
De Moerloose, B.2
Laureys, G.3
Kint, J.4
Ferster, A.5
De Bacquer, D.6
Philippe, J.7
Benoit, Y.8
-
59
-
-
0030788969
-
Optimal immunocytochemical and flow cytometric detection of P-gp, MRP and LRP in childhood acute lymphoblastic leukemia
-
(1997)
Leukemia
, vol.11
, pp. 1078-1085
-
-
Den Boer, M.L.1
Zwaan, C.M.2
Pieters, R.3
Kazemier, K.M.4
Rottier, M.M.5
Flens, M.J.6
Scheper, R.J.7
Veerman, A.J.8
-
64
-
-
0032579517
-
A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and the transporter within the plasma membrane of tumor cells
-
(1998)
J Biol Chem
, vol.273
, pp. 2526-2531
-
-
Roy, K.1
Tolner, B.2
Chiao, J.H.3
Sirotnak, F.M.4
-
65
-
-
0032563287
-
A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function
-
(1998)
J Biol Chem
, vol.273
, pp. 19065-19071
-
-
Zhao, R.1
Assaraf, Y.G.2
Goldman, I.D.3
-
66
-
-
0032478826
-
A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate
-
(1998)
J Biol Chem
, vol.273
, pp. 7873-7879
-
-
Zhao, R.1
Assaraf, Y.G.2
Goldman, I.D.3
-
73
-
-
0030837677
-
ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients
-
(1997)
Nephrol Dial Transplant
, vol.12
, Issue.SUPPL. 2
, pp. 42-46
-
-
Van der Kleij, F.G.1
Navis, G.J.2
Gansevoort, R.T.3
Heeg, J.E.4
Scheffer, H.5
De Zeeuw, D.6
De Jong, P.E.7
-
74
-
-
7144223417
-
Angiotensin-converting enzyme gene polymorphism determines the antiproteinuric and systemic hemodynamic effect of enalapril in patients with proteinuric renal disease
-
Austrian Study Group of the Effects of Enalapril Treatment in Proteinuric Renal Disease
-
(1998)
Kidney Blood Press Res
, vol.21
, pp. 66-69
-
-
Haas, M.1
Yilmaz, N.2
Schmidt, A.3
Neyer, U.4
Arneitz, K.5
Stummvoll, H.K.6
Wallner, M.7
Auinger, M.8
Arias, I.9
Schneider, B.10
Mayer, G.11
-
77
-
-
0030474233
-
Relationship between the angiotensin converting enzyme gene polymorphism and the effects of enalapril on left ventricular hypertrophy and impaired echocardiographic studies
-
(1996)
J Hypertens
, vol.14
, pp. 1403-1408
-
-
Sasaki, M.1
Oki, T.2
Iuchi, A.3
Tabata, T.4
Yamada, H.5
Manabe, K.6
Fukuda, K.7
Abe, M.8
Ito, S.9
-
78
-
-
0031053270
-
Renal hemodynamic changes induced by captopril and angiotensin-converting enzyme gene polymorphism
-
(1997)
Nephron
, vol.75
, pp. 310-314
-
-
Mizuiri, S.1
Hemmi, H.2
Inoue, A.3
Takano, M.4
Kadomatsu, S.5
Tanimoto, H.6
Tanegashima, M.7
Hayashi, I.8
Fushimi, T.9
Hasegawa, A.10
-
79
-
-
0028848097
-
Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy
-
(1995)
J Clin Invest
, vol.96
, pp. 2162-2169
-
-
Yoshida, H.1
Mitarai, T.2
Kawamura, T.3
Kitajima, T.4
Miyazaki, Y.5
Nagasawa, R.6
Kawaguchi, Y.7
Kubo, H.8
Ichikawa, I.9
Sakai, O.10
-
80
-
-
0031925068
-
Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene
-
(1998)
Diabetes
, vol.47
, pp. 598-605
-
-
Hansen, T.1
Echwald, S.M.2
Hansen, L.3
Moller, A.M.4
Almind, K.5
Clausen, J.O.6
Urhammer, S.A.7
Inoue, H.8
Ferrer, J.9
Bryan, J.10
Aguilar-Bryan, L.11
Permutt, M.A.12
Pedersen, O.13
-
82
-
-
9044250848
-
Thymidylate synthase mRNA level in adenocarcinoma of the stomach: A predictor for primary tumor response and overall survival
-
(1996)
J Clin Oncol
, vol.14
, pp. 176-182
-
-
Lenz, H.J.1
Leichman, C.G.2
Danenberg, K.D.3
Danenberg, P.V.4
Groshen, S.5
Cohen, H.6
Laine, L.7
Crookes, P.8
Silberman, H.9
Baranda, J.10
Garcia, Y.11
Li, J.12
Leichman, L.13
-
83
-
-
0030883708
-
Quantitation of intratumoral thymidylate synthase expression predicts for dissfeminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
-
(1997)
J Clin Oncol
, vol.15
, pp. 3223-3229
-
-
Leichman, C.G.1
Lenz, H.J.2
Leichman, L.3
Danenberg, K.4
Baranda, J.5
Groshen, S.6
Boswell, W.7
Metzger, R.8
Tan, M.9
Danenberg, P.V.10
-
84
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
Lenz, H.J.7
Leichman, C.G.8
Leichman, L.9
Diasio, R.B.10
Danenberg, P.V.11
-
88
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
(1996)
Nature Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
90
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
(2001)
New Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
91
-
-
0035810142
-
Activity of a specific inhibitor of the Bcr-Abl tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
(2001)
New Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
93
-
-
0034210577
-
Mechanism of resistance to the Abl tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines
-
(2000)
Blood
, vol.95
, pp. 3498-3505
-
-
Weisberg, E.1
Griffin, J.D.2
-
94
-
-
0034161460
-
Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Le Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
Barni, R.4
Mologni, L.5
Cabrita, G.6
Marchesi, E.7
Supino, R.8
Gambacorti-Passerini, C.9
-
96
-
-
0033519986
-
High incidence of secondary brain tumours after radiotherapy and antimetabolites
-
(1999)
Lancet
, vol.354
, pp. 34-39
-
-
Relling, M.V.1
Rubnitz, J.E.2
Rivera, G.K.3
Boyett, J.M.4
Hancock, M.L.5
Felix, C.A.6
Kun, L.E.7
Walter, A.W.8
Evans, W.E.9
Pui, C.H.10
-
103
-
-
13144282667
-
Association of CYP3A4 genotype with treatment-related leukemia
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13176-13181
-
-
Felix, C.A.1
Walker, A.H.2
Lange, B.J.3
Williams, T.M.4
Winick, N.J.5
Cheung, N.K.6
Lovett, B.D.7
Nowell, P.C.8
Blair, I.A.9
Rebbeck, T.R.10
|