Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier

Journal of Biological Chemistry

Volumn 274, Issue 15, 1999, Pages 10388-10394

  Wong, So C ^a,b   Zhang, Long ^a   Witt, Teah L ^a   Proefke, Susan A ^a   Bhushan, Alok ^c   Matherly, Larry H ^a,b  

^a KARMANOS CANCER INSTITUTE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c IDAHO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FOLIC ACID; METHOTREXATE;

ACTIVE TRANSPORT; ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; SEQUENCE ANALYSIS;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL MEMBRANE; CRICETINAE; DRUG RESISTANCE, NEOPLASM; FOLIC ACID; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; METHOTREXATE; MUTATION; PHENOTYPE; PROTEIN BIOSYNTHESIS; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0033537838     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.15.10388     Document Type: Article

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