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Volumn 19, Issue 8, 2001, Pages 2293-2301

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

EID: 0035871560     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.8.2293     Document Type: Article
Times cited : (419)

References (39)
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    • McLeod, H.L.1    Relling, M.V.2    Liu, Q.3
  • 5
    • 0029919807 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase deficiency: Two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians
    • (1996) Am J Hum Genet , vol.58 , pp. 694-702
    • Tai, H.L.1    Krynetski, E.Y.2    Yates, C.R.3
  • 13
    • 0032693405 scopus 로고    scopus 로고
    • Enhanced proteasomal degradation of mutant human thiopurine S-methyltransferase (TPMT) in mammalian cells: Mechanism for TPMT protein deficiency inherited by TPMT*2, TPMT*3A, TPMT*3B or TPMT*3C
    • (1999) Pharmacogenetics , vol.9 , pp. 641-650
    • Tai, H.-L.1    Fessing, M.2    Bonten, E.J.3
  • 19
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • (1991) J Pediatr , vol.119 , pp. 985-989
    • Evans, W.E.1    Horner, M.2    Chu, Y.Q.3
  • 22
    • 0030871031 scopus 로고    scopus 로고
    • Azathioprine-induced severe pancytopenia due to a homozygous two-point mutation of the thiopurine methyltransferase gene in a patient with juvenile HLA-B27-associated spondylarthritis
    • (1997) Arthritis Rheum , vol.40 , pp. 1896-1898
    • Leipold, G.1    Schutz, E.2    Haas, J.P.3
  • 26
    • 0027401302 scopus 로고
    • Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • (1993) Lancet , vol.341 , pp. 436
    • Schutz, E.1    Gummert, J.2    Mohr, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.