-
1
-
-
0028243181
-
Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases
-
Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW and Ross D (1994) Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases. Cancer Res 54: 3196-3201
-
(1994)
Cancer Res
, vol.54
, pp. 3196-3201
-
-
Beall, H.D.1
Mulcahy, R.T.2
Siegel, D.3
Traver, R.D.4
Gibson, N.W.5
Ross, D.6
-
2
-
-
0019142866
-
Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity
-
Benson A, Hunkeler MJ and Talalay P (1980) Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77: 5216-5220
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 5216-5220
-
-
Benson, A.1
Hunkeler, M.J.2
Talalay, P.3
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Biochemistry 72: 248-254
-
(1976)
Biochemistry
, vol.72
, pp. 248-254
-
-
Bradford, M.1
-
4
-
-
0026240006
-
Relevance of metabolic polymorphisms to human carcinogenesis: Evaluation of epidemiologic evidence
-
Caporaso N, Landi MT and Vineis P (1991) Relevance of metabolic polymorphisms to human carcinogenesis: evaluation of epidemiologic evidence. Pharmacogenetics 1:4-19
-
(1991)
Pharmacogenetics
, vol.1
, pp. 4-19
-
-
Caporaso, N.1
Landi, M.T.2
Vineis, P.3
-
6
-
-
0028178833
-
Expression of NAD(P)H:quinone oxidoreductase and glutathione S-transferases alpha and pi in human renal cell carcinoma and in kidney cancer-derived cell lines
-
Eickelmann P, Ebert T, Warskulat U, Schulz WA and Sies H (1994a) Expression of NAD(P)H:quinone oxidoreductase and glutathione S-transferases alpha and pi in human renal cell carcinoma and in kidney cancer-derived cell lines. Carcinogenesis 15: 219-225
-
(1994)
Carcinogenesis
, vol.15
, pp. 219-225
-
-
Eickelmann, P.1
Ebert, T.2
Warskulat, U.3
Schulz, W.A.4
Sies, H.5
-
7
-
-
0028467127
-
Loss of heterozygosity at the NAD(P)H: Quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line
-
Eickelmann P, Schulz WA, Ronde D, Schmitz-Drager B and Sies H (1944b) Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line. Biol Chem Hoppe-Seyler 375: 439-445
-
(1944)
Biol Chem Hoppe-Seyler
, vol.375
, pp. 439-445
-
-
Eickelmann, P.1
Schulz, W.A.2
Ronde, D.3
Schmitz-Drager, B.4
Sies, H.5
-
8
-
-
0028178821
-
Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones
-
Enger PA, Kensler TW, Prestera T, Talalay P, Libby AH, Joyner HH and Curhey TJ (1994) Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis 15: 177-181
-
(1994)
Carcinogenesis
, vol.15
, pp. 177-181
-
-
Enger, P.A.1
Kensler, T.W.2
Prestera, T.3
Talalay, P.4
Libby, A.H.5
Joyner, H.H.6
Curhey, T.J.7
-
9
-
-
77957000392
-
DT-Diaphorase
-
Ernster L (1967) DT-Diaphorase. Methods Enzymol 10: 309-317
-
(1967)
Methods Enzymol
, vol.10
, pp. 309-317
-
-
Ernster, L.1
-
10
-
-
0015881843
-
A rapid micromethod for determination of FMN and FAD in mixtures
-
Faeder EJ and Siegel LM (1973) A rapid micromethod for determination of FMN and FAD in mixtures. Anal Biochem 53: 332-336
-
(1973)
Anal Biochem
, vol.53
, pp. 332-336
-
-
Faeder, E.J.1
Siegel, L.M.2
-
11
-
-
0027055783
-
Cell-specific metabolism in mouse bone marrow stroma. Studies of activation and detoxification of benzene metabolites
-
Ganousis LG, Goon D, Zyglewska T, Wu KK and Ross D (1992) Cell-specific metabolism in mouse bone marrow stroma. Studies of activation and detoxification of benzene metabolites. Mol Pharmacol 42: 531-536
-
(1992)
Mol Pharmacol
, vol.42
, pp. 531-536
-
-
Ganousis, L.G.1
Goon, D.2
Zyglewska, T.3
Wu, K.K.4
Ross, D.5
-
12
-
-
0027048768
-
Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity
-
Gibson NW, Hartley JA, Butler J, Siegel D and Ross D (1992) Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity. Mol Pharmacol 42: 531-536
-
(1992)
Mol Pharmacol
, vol.42
, pp. 531-536
-
-
Gibson, N.W.1
Hartley, J.A.2
Butler, J.3
Siegel, D.4
Ross, D.5
-
14
-
-
0027983085
-
Pharmacogenetic phenotyping and genotyping. Present status and future potential
-
Gonzalez FJ and Idle JR (1994) Pharmacogenetic phenotyping and genotyping. Present status and future potential. Clin Pharmacokinet 26: 59-70
-
(1994)
Clin Pharmacokinet
, vol.26
, pp. 59-70
-
-
Gonzalez, F.J.1
Idle, J.R.2
-
15
-
-
0026319263
-
Human NAD(P)H:quinone oxidoreductase (NQOI) gene structure and induction by dioxin
-
Jaiswal AK (1991) Human NAD(P)H:quinone oxidoreductase (NQOI) gene structure and induction by dioxin. Biochemistry 30: 10647-10653
-
(1991)
Biochemistry
, vol.30
, pp. 10647-10653
-
-
Jaiswal, A.K.1
-
16
-
-
0023724493
-
Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16
-
Jaiswal KA, Mcbride OW, Adesnik M and Nebert DW (1988) Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16. J Biol Chem 263: 13572-13578
-
(1988)
J Biol Chem
, vol.263
, pp. 13572-13578
-
-
Jaiswal, K.A.1
Mcbride, O.W.2
Adesnik, M.3
Nebert, D.W.4
-
17
-
-
0029151835
-
Presence of a heterozygous substitution and its relationship to DT-diaphorase activity
-
Kuehl BL, Paterson JWE, Peacock JW, Paterson MC, and Rauth AM (1995) Presence of a heterozygous substitution and its relationship to DT-diaphorase activity. Br J Cancer 72: 555-561
-
(1995)
Br J Cancer
, vol.72
, pp. 555-561
-
-
Kuehl, B.L.1
Paterson, J.W.E.2
Peacock, J.W.3
Paterson, M.C.4
Rauth, A.M.5
-
18
-
-
0029636702
-
Re: Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer
-
Kolesar JM, Burris HA and Kuhn JG (1995) Re: detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer. J Natl Cancer Inst 87: 1022-1024
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1022-1024
-
-
Kolesar, J.M.1
Burris, H.A.2
Kuhn, J.G.3
-
19
-
-
0029068515
-
The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprevention and chemotherapy: Mechanism of the two-electron reduction
-
LI R, Bianchet MA, Talalay P and Amzel LM (1995) The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprevention and chemotherapy: mechanism of the two-electron reduction. Proc Natl Acad Sci USA 92: 8846-8850
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8846-8850
-
-
Li, R.1
Bianchet, M.A.2
Talalay, P.3
Amzel, L.M.4
-
20
-
-
0026499189
-
Identification of a glycine-rich sequence as an NAD(P)H-binding site and tyrosine 128 as a dicumarol-binding site in rat liver NAD(P)H:quinone oxidoreductase by site-directed mutagenesis
-
MA Q, CUI K, Xiao F, LU Ayh and Yang CS (1992) Identification of a glycine-rich sequence as an NAD(P)H-binding site and tyrosine 128 as a dicumarol-binding site in rat liver NAD(P)H:quinone oxidoreductase by site-directed mutagenesis. J Biol Chem 267: 22298-22304
-
(1992)
J Biol Chem
, vol.267
, pp. 22298-22304
-
-
Ma, Q.1
Cui, K.2
Xiao, F.3
Lu, A.4
Yang, C.S.5
-
21
-
-
0026700546
-
Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: Relationship to the response of lung tumor xenografts to mitomycin Cl
-
Malkinson AM, Siegel D, Forrest GL, Gazdar AF, Oie HK, Chan DC, Bunn PA, Mabry M, Dykes DJ, Harrison SD and Ross D (1992) Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cl. Cancer Res 52: 4752-4757
-
(1992)
Cancer Res
, vol.52
, pp. 4752-4757
-
-
Malkinson, A.M.1
Siegel, D.2
Forrest, G.L.3
Gazdar, A.F.4
Oie, H.K.5
Chan, D.C.6
Bunn, P.A.7
Mabry, M.8
Dykes, D.J.9
Harrison, S.D.10
Ross, D.11
-
22
-
-
0025799465
-
DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family
-
Marshall RS, Paterson MC and Rauth AM (1991a) DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family. Carcinogenesis 12: 1175-1180
-
(1991)
Carcinogenesis
, vol.12
, pp. 1175-1180
-
-
Marshall, R.S.1
Paterson, M.C.2
Rauth, A.M.3
-
23
-
-
0026032132
-
Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual
-
Marshall RS, Paterson MC and Rauth AM (1991b) Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual. Biochem Pharmacol 41: 1351-1360
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 1351-1360
-
-
Marshall, R.S.1
Paterson, M.C.2
Rauth, A.M.3
-
24
-
-
0025201144
-
A simple and fast method to extract RNA from tissue culture cells
-
Peppel K and Baglioni C (1990) A simple and fast method to extract RNA from tissue culture cells. Biotechniques 9: 711-713
-
(1990)
Biotechniques
, vol.9
, pp. 711-713
-
-
Peppel, K.1
Baglioni, C.2
-
25
-
-
0027376465
-
Semi-quantitative measurement of gene expression byRT-PCR: A cautionary tale
-
Phillips RM, Sarang M and Gibson NW (1993) Semi-quantitative measurement of gene expression byRT-PCR: a cautionary tale. Int J Oncol 3: 1097-1102
-
(1993)
Int J Oncol
, vol.3
, pp. 1097-1102
-
-
Phillips, R.M.1
Sarang, M.2
Gibson, N.W.3
-
26
-
-
0026589840
-
Rapid detection of inducers of enzymes that protect against carcinogens
-
Prochaska HJ, Santamaria AB and Talalay P (1992) Rapid detection of inducers of enzymes that protect against carcinogens. Proc Natl Acad Sci USA 89: 2394-2398
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2394-2398
-
-
Prochaska, H.J.1
Santamaria, A.B.2
Talalay, P.3
-
27
-
-
0025131538
-
Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma
-
Ross D, Siegel D, Gibson NW, Pacheco D, Thomas DJ, Reasor M and Wierda D (1990) Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma. Free Rad Res Commun 8: 373-381
-
(1990)
Free Rad Res Commun
, vol.8
, pp. 373-381
-
-
Ross, D.1
Siegel, D.2
Gibson, N.W.3
Pacheco, D.4
Thomas, D.J.5
Reasor, M.6
Wierda, D.7
-
28
-
-
0027295491
-
DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of milomycin C
-
Ross D, Siegel D, Beall HD, Prakash AS, Mulcahy RT and Gibson NW (1993) DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of milomycin C. Cancer Metast Rev 12: 83-101
-
(1993)
Cancer Metast Rev
, vol.12
, pp. 83-101
-
-
Ross, D.1
Siegel, D.2
Beall, H.D.3
Prakash, A.S.4
Mulcahy, R.T.5
Gibson, N.W.6
-
29
-
-
0029781444
-
A polymorphism in NAD(P)H: Quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity
-
Ross D, Traver RD, Siegel D, Kuehl BL, Misra V and Rauth AM (1996) A polymorphism in NAD(P)H: quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity. Br J Cancer 74: 995-996
-
(1996)
Br J Cancer
, vol.74
, pp. 995-996
-
-
Ross, D.1
Traver, R.D.2
Siegel, D.3
Kuehl, B.L.4
Misra, V.5
Rauth, A.M.6
-
30
-
-
0029073531
-
Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking
-
Rosvold EA, Mcglynn KA, Lustbader ED and Buetow KH (1995a) Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking. Pharmacogenetics 5: 199-206
-
(1995)
Pharmacogenetics
, vol.5
, pp. 199-206
-
-
Rosvold, E.A.1
Mcglynn, K.A.2
Lustbader, E.D.3
Buetow, K.H.4
-
31
-
-
0029636702
-
Re: Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer
-
Rosvold EA, Mcglynn KA, Lustbader ED and Buetow KH (1995b) Re: detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer. J Natl Cancer Ins 87: 1022-1024
-
(1995)
J Natl Cancer Ins
, vol.87
, pp. 1022-1024
-
-
Rosvold, E.A.1
Mcglynn, K.A.2
Lustbader, E.D.3
Buetow, K.H.4
-
32
-
-
0007521867
-
Lack of NAD(P)H:quinone oridoreductase activity (NQO1) is associated with increased risk of benzene hematotoxicity
-
Rothman N, Traver RD, Smith MT, Hayes RB, LI GL, Campleman S, Dosemecci M, Zhang L, Linet M, Wacholder S, Yin SN and Ross D (1996) Lack of NAD(P)H:quinone oridoreductase activity (NQO1) is associated with increased risk of benzene hematotoxicity. Proc Am Assoc Cancer Res 37: 258
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 258
-
-
Rothman, N.1
Traver, R.D.2
Smith, M.T.3
Hayes, R.B.4
Li, G.L.5
Campleman, S.6
Dosemecci, M.7
Zhang, L.8
Linet, M.9
Wacholder, S.10
Yin, S.N.11
Ross, D.12
-
33
-
-
0025248106
-
Cytosolic NAD(P)H:(quinone-acceptor) oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol
-
Schlager JJ and Powis G (1990) Cytosolic NAD(P)H:(quinone-acceptor) oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol. Int J Cancer 45: 403-409
-
(1990)
Int J Cancer
, vol.45
, pp. 403-409
-
-
Schlager, J.J.1
Powis, G.2
-
34
-
-
0025688249
-
Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells
-
Siegel D, Gibson NW, Preusch, PC and Ross D (1990) Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells. Cancer Res 50: 7483-7489
-
(1990)
Cancer Res
, vol.50
, pp. 7483-7489
-
-
Siegel, D.1
Gibson, N.W.2
Preusch, P.C.3
Ross, D.4
-
35
-
-
0024386604
-
Purification by cibacron blue F3GA dye affinity chromatography and comparison of NAD(P)H:quinone reductase (E.C.I.6.99.2) from rat liver cytosol and microsomes
-
Sharkis DH and Swenson RP (1989) Purification by cibacron blue F3GA dye affinity chromatography and comparison of NAD(P)H:quinone reductase (E.C.I.6.99.2) from rat liver cytosol and microsomes. Biochem Biophys Res Commun 161:434-441
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 434-441
-
-
Sharkis, D.H.1
Swenson, R.P.2
-
36
-
-
0026505943
-
NAD(P)H:quinone oxidoreductase gene expression in humun colon carcinoma cells: Characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
-
Traver RD, Horikoshi T, Danenberg KD, Stadlbauer THW, Danenberg PV, Ross D and Gibson NW (1992) NAD(P)H:quinone oxidoreductase gene expression in humun colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res 52: 797-802
-
(1992)
Cancer Res
, vol.52
, pp. 797-802
-
-
Traver, R.D.1
Horikoshi, T.2
Danenberg, K.D.3
Stadlbauer, T.H.W.4
Danenberg, P.V.5
Ross, D.6
Gibson, N.W.7
-
37
-
-
0012469630
-
A point mutation in both human lung and colon carcinoma cell lines leading to a loss of DT-diaphorase activity
-
Traver RD, Phillips RM, Gibson NW and Ross D (1995) A point mutation in both human lung and colon carcinoma cell lines leading to a loss of DT-diaphorase activity. Proc Am Assoc Cancer Res 36: 525
-
(1995)
Proc Am Assoc Cancer Res
, vol.36
, pp. 525
-
-
Traver, R.D.1
Phillips, R.M.2
Gibson, N.W.3
Ross, D.4
-
38
-
-
0025284525
-
Enzymology of the reductive bioactivation of SR 4233. A novel benzotriazine di-N-oxide hypoxic cell cytotoxin
-
Walton MI and Workman P (1990) Enzymology of the reductive bioactivation of SR 4233. A novel benzotriazine di-N-oxide hypoxic cell cytotoxin. Biochem Pharmacol 39: 1735-1742
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 1735-1742
-
-
Walton, M.I.1
Workman, P.2
-
39
-
-
0021934758
-
Chemoprevention of cancer
-
Wattenberg LW (1985) Chemoprevention of cancer. Cancer Res 45: 1-8
-
(1985)
Cancer Res
, vol.45
, pp. 1-8
-
-
Wattenberg, L.W.1
-
40
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
-
Zhang Y, Talalay P, Cho CG and Posner GH (1992) A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
|