-
1
-
-
0021802841
-
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
-
Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature. 1985;315:550.
-
(1985)
Nature
, vol.315
, pp. 550
-
-
Shtivelman, E.1
Lifshitz, B.2
Gale, R.P.3
Canaani, E.4
-
2
-
-
0021811764
-
Structural organization of the bcr gene and its role in the Ph' translocation
-
Heisterkamp N, Stam K, Groffen J, de Klein A, Grosveld G. Structural organization of the bcr gene and its role in the Ph' translocation. Nature. 1985;315:758.
-
(1985)
Nature
, vol.315
, pp. 758
-
-
Heisterkamp, N.1
Stam, K.2
Groffen, J.3
De Klein, A.4
Grosveld, G.5
-
3
-
-
0022544401
-
The chronic myelogenous leukemia-specific P210 protein is the product of the Bcr/Abl hybrid gene
-
Ben-Neriah Y, Daley GQ, Mes-Masson AM, Witte ON, Baltimore D. The chronic myelogenous leukemia-specific P210 protein is the product of the Bcr/Abl hybrid gene. Science. 1986;233:212.
-
(1986)
Science
, vol.233
, pp. 212
-
-
Ben-Neriah, Y.1
Daley, G.Q.2
Mes-Masson, A.M.3
Witte, O.N.4
Baltimore, D.5
-
4
-
-
0023263055
-
The CML-specific P210 Bcr/Abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts
-
Daley GQ, McLaughlin J, Witte ON, Baltimore D. The CML-specific P210 Bcr/Abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts. Science. 1987;237:532.
-
(1987)
Science
, vol.237
, pp. 532
-
-
Daley, G.Q.1
McLaughlin, J.2
Witte, O.N.3
Baltimore, D.4
-
5
-
-
0001044842
-
Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210Bcr/Abl protein
-
Daley GQ, Baltimore D. Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210Bcr/Abl protein. Proc Natl Acad Sci U S A. 1988;85:9312.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 9312
-
-
Daley, G.Q.1
Baltimore, D.2
-
6
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 1990;247:1079.
-
(1990)
Science
, vol.247
, pp. 1079
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
7
-
-
0027422977
-
A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins
-
McWhirter JR, Galasso DL, Wang JY. A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins. Mol Cell Biol. 1993;13:7587.
-
(1993)
Mol Cell Biol.
, vol.13
, pp. 7587
-
-
McWhirter, J.R.1
Galasso, D.L.2
Wang, J.Y.3
-
8
-
-
0024240990
-
Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors
-
Yaish P, Gazit A, Gilon C, Levitzki A. Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science. 1988;242:933.
-
(1988)
Science
, vol.242
, pp. 933
-
-
Yaish, P.1
Gazit, A.2
Gilon, C.3
Levitzki, A.4
-
9
-
-
0027332537
-
Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate
-
Anafi M, Gazit A, Zehavi A, Ben-Neriah Y, Levitzki A. Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate. Blood. 1993;82:3524.
-
(1993)
Blood
, vol.82
, pp. 3524
-
-
Anafi, M.1
Gazit, A.2
Zehavi, A.3
Ben-Neriah, Y.4
Levitzki, A.5
-
10
-
-
0028227405
-
Tyrphostin induced growth inhibition: Correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia
-
Kaur G, Gazit A, Levitzki A, Stowe E, Cooney DA, Sausville EA. Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia. Anticancer Drugs. 1994;5:213.
-
(1994)
Anticancer Drugs
, vol.5
, pp. 213
-
-
Kaur, G.1
Gazit, A.2
Levitzki, A.3
Stowe, E.4
Cooney, D.A.5
Sausville, E.A.6
-
11
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger E, Zimmermann J, Mett H, et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res. 1996;56:100.
-
(1996)
Cancer Res.
, vol.56
, pp. 100
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
-
12
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2:561.
-
(1996)
Nat Med.
, vol.2
, pp. 561
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
13
-
-
0030853063
-
The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells
-
Deininger MW, Goldman JM, Lydon N, Melo JV. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells. Blood. 1997;90:3691.
-
(1997)
Blood
, vol.90
, pp. 3691
-
-
Deininger, M.W.1
Goldman, J.M.2
Lydon, N.3
Melo, J.V.4
-
14
-
-
0031409736
-
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL + leukemic cells and induces apoptosis
-
Gambacorti-Passerini C, le Coutre P, Mologni L, et al. Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL + leukemic cells and induces apoptosis. Blood Cells Mol Dis. 1997;23: 380.
-
(1997)
Blood Cells Mol Dis.
, vol.23
, pp. 380
-
-
Gambacorti-Passerini, C.1
Le Coutre, P.2
Mologni, L.3
-
15
-
-
0031869466
-
Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR-ABL tyrosine kinase, CGP 57148
-
Dan S, Naito M, Tsuruo T. Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR-ABL tyrosine kinase, CGP 57148. Cell Death Differ. 1998;5:710.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 710
-
-
Dan, S.1
Naito, M.2
Tsuruo, T.3
-
16
-
-
15444350807
-
Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
-
Beran M, Cao X, Estrov Z, et al. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clin Cancer Res. 1998;4:1661.
-
(1998)
Clin Cancer Res.
, vol.4
, pp. 1661
-
-
Beran, M.1
Cao, X.2
Estrov, Z.3
-
17
-
-
0031454003
-
CGP57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
Carroll M, Ohno-Jones S, Tamura S, et al. CGP57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood. 1997;90:4947.
-
(1997)
Blood
, vol.90
, pp. 4947
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
-
18
-
-
0000199137
-
Clinical efficacy and safety of an ABL specific tyrosine kinase inhibitor as targeted therapy for chronic myelogenous leukemia
-
Druker BJ, Talpaz M, Resta D, et al. Clinical efficacy and safety of an ABL specific tyrosine kinase inhibitor as targeted therapy for chronic myelogenous leukemia [abstract]. Blood. 1999; 99(suppl 1):368a.
-
(1999)
Blood
, vol.99
, Issue.SUPPL. 1
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.3
-
19
-
-
0033585504
-
In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor
-
le Coutre P, Mologni L, Cleris L, et al. In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor. J Natl Cancer Inst. 1999;91:163.
-
(1999)
J Natl Cancer Inst.
, vol.91
, pp. 163
-
-
Le Coutre, P.1
Mologni, L.2
Cleris, L.3
-
21
-
-
0031840623
-
Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR
-
Mensink E, van de Locht A, Schattenberg A, et al. Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR. Br J Haematol. 1998;102:768.
-
(1998)
Br J Haematol.
, vol.102
, pp. 768
-
-
Mensink, E.1
Van De Locht, A.2
Schattenberg, A.3
-
22
-
-
0031751078
-
Chromosomal fragile sites and DNA amplification in drug-resistant cells
-
Kuo MT, Sen S, Hittelman WN, Hsu TC. Chromosomal fragile sites and DNA amplification in drug-resistant cells. Biochem Pharmacol. 1998;56:7.
-
(1998)
Biochem Pharmacol.
, vol.56
, pp. 7
-
-
Kuo, M.T.1
Sen, S.2
Hittelman, W.N.3
Hsu, T.C.4
-
23
-
-
0032496226
-
Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells
-
Tong Y, Liu-Chen X, Ercikan-Abali EA, et al. Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells. J Biol Chem. 1998;273:11,611.
-
(1998)
J Biol Chem.
, vol.273
, pp. 11611
-
-
Tong, Y.1
Liu-Chen, X.2
Ercikan-Abali, E.A.3
-
24
-
-
0020572078
-
Chromosome-mediated gene transfer of hydroxurea resistance and amplification of ribonucleotide activity
-
Lewis WH, Srinivasan PR. Chromosome-mediated gene transfer of hydroxurea resistance and amplification of ribonucleotide activity. Mol Cell Biol. 1983;3:1053.
-
(1983)
Mol Cell Biol.
, vol.3
, pp. 1053
-
-
Lewis, W.H.1
Srinivasan, P.R.2
-
25
-
-
0027365944
-
Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts
-
Schaefer DI, Livanos EM, White AE, Tisty TD. Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts. Cancer Res. 1993;53: 4946.
-
(1993)
Cancer Res.
, vol.53
, pp. 4946
-
-
Schaefer, D.I.1
Livanos, E.M.2
White, A.E.3
Tisty, T.D.4
-
26
-
-
0027982007
-
Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells
-
Kuo MT, Vyas RC, Jiang LX, Hittelman WN. Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells. Mol Cell Biol. 1994;14:5202.
-
(1994)
Mol Cell Biol.
, vol.14
, pp. 5202
-
-
Kuo, M.T.1
Vyas, R.C.2
Jiang, L.X.3
Hittelman, W.N.4
-
27
-
-
0030904279
-
Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
-
Coquelle A, Pipiras E, Toledo F, Buttin G, Debatisse M. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons. Cell. 1997; 89:215.
-
(1997)
Cell
, vol.89
, pp. 215
-
-
Coquelle, A.1
Pipiras, E.2
Toledo, F.3
Buttin, G.4
Debatisse, M.5
-
28
-
-
0018864968
-
Satellite DNA in large marker chromosomes of methotrexate-resistant mouse cells
-
Bostock CJ, Clark EM. Satellite DNA in large marker chromosomes of methotrexate-resistant mouse cells. Cell. 1980;19:709.
-
(1980)
Cell
, vol.19
, pp. 709
-
-
Bostock, C.J.1
Clark, E.M.2
-
29
-
-
0029045777
-
The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: Evidence that chromosome breakage plays a key role in MRP or LRP gene amplification
-
Slovak ML, Ho JP, Cole SP, et al. The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. Cancer Res. 1995;55:4214.
-
(1995)
Cancer Res.
, vol.55
, pp. 4214
-
-
Slovak, M.L.1
Ho, J.P.2
Cole, S.P.3
-
30
-
-
0028961799
-
Mechanisms of MRP over-expression in four human lung-cancer cell lines and analysis of the MRP amplicon
-
Eijdems EW, De Haas M, Coco-Martin JM, et al. Mechanisms of MRP over-expression in four human lung-cancer cell lines and analysis of the MRP amplicon. Int J Cancer. 1995;60:676.
-
(1995)
Int J Cancer.
, vol.60
, pp. 676
-
-
Eijdems, E.W.1
De Haas, M.2
Coco-Martin, J.M.3
-
31
-
-
0032132806
-
A new role for hypoxia in tumor progression: Induction of fragile site triggering genomic rearrangements and formation of complex DMs ad HSRs
-
Coquelle A, Toledo F, Stern S, Bieth A, Debatisse M. A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs ad HSRs. Mol Cell. 1998;2:259.
-
(1998)
Mol Cell.
, vol.2
, pp. 259
-
-
Coquelle, A.1
Toledo, F.2
Stern, S.3
Bieth, A.4
Debatisse, M.5
-
32
-
-
0022981185
-
Breakpoints on chromosomes 9 and 22 in Philadelphia chromosome-positive chronic myelogenous leukemia (CML): Amplification of rearranged c-Abl oncogenes in CML blast crisis
-
Collins SJ. Breakpoints on chromosomes 9 and 22 in Philadelphia chromosome-positive chronic myelogenous leukemia (CML): amplification of rearranged c-Abl oncogenes in CML blast crisis. J Clin Invest. 1986;78:1392.
-
(1986)
J Clin Invest.
, vol.78
, pp. 1392
-
-
Collins, S.J.1
-
33
-
-
0023155043
-
Chronic myelogenous leukemia: Amplification of a rearranged c-Abl oncogene in both chronic phase and blast crisis
-
Collins SJ, Groudine MT. Chronic myelogenous leukemia: amplification of a rearranged c-Abl oncogene in both chronic phase and blast crisis. Blood. 1987;69:893.
-
(1987)
Blood
, vol.69
, pp. 893
-
-
Collins, S.J.1
Groudine, M.T.2
-
34
-
-
0029042707
-
Extensive amplification of Bcr/Abl fusion genes clustered on three marker chromosomes in human leukemic cell line K-562
-
Wu SQ, Voelkerding KV, Sabatini L, Chen XR, Huang J, Meisner LF. Extensive amplification of Bcr/Abl fusion genes clustered on three marker chromosomes in human leukemic cell line K-562. Leukemia. 1995;9:858.
-
(1995)
Leukemia
, vol.9
, pp. 858
-
-
Wu, S.Q.1
Voelkerding, K.V.2
Sabatini, L.3
Chen, X.R.4
Huang, J.5
Meisner, L.F.6
-
35
-
-
0026711242
-
Efficient inhibition of p-glycoprotein-mediated multidrug resistance with a monoclonal antibody
-
Mechetner EB, Roninson IB. Efficient inhibition of p-glycoprotein-mediated multidrug resistance with a monoclonal antibody. Proc Natl Acad Sci U S A. 1992;89:5824.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 5824
-
-
Mechetner, E.B.1
Roninson, I.B.2
-
36
-
-
0027285463
-
Establishment and characterization of multidrug-resistant human osteosarcoma cell lines
-
Serra M, Scotlandi K, Manara MC, et al. Establishment and characterization of multidrug-resistant human osteosarcoma cell lines. Anticancer Res. 1993;13:323.
-
(1993)
Anticancer Res.
, vol.13
, pp. 323
-
-
Serra, M.1
Scotlandi, K.2
Manara, M.C.3
|