-
1
-
-
33745464490
-
Fluorinated pyrimidines: A new class of tumor inhibitory compounds
-
Heidelberger C, Chandari NK, Dannenberg P, et al: Fluorinated pyrimidines: A new class of tumor inhibitory compounds. Nature 179:663-666, 1957
-
(1957)
Nature
, vol.179
, pp. 663-666
-
-
Heidelberger, C.1
Chandari, N.K.2
Dannenberg, P.3
-
2
-
-
0015962412
-
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyruridylate
-
Santi DV, McHenry CS, Sommer H: Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyruridylate. Biochemistry 13:471-481, 1974
-
(1974)
Biochemistry
, vol.13
, pp. 471-481
-
-
Santi, D.V.1
McHenry, C.S.2
Sommer, H.3
-
3
-
-
0019349301
-
Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice
-
Hougton JA, Maroda SJ, Phillips JO, et al: Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice. Cancer Res 41:144-149, 1981
-
(1981)
Cancer Res
, vol.41
, pp. 144-149
-
-
Hougton, J.A.1
Maroda, S.J.2
Phillips, J.O.3
-
4
-
-
0020504093
-
Altered thymidylate synthase in 5-fluorodeoxyuridine-resistant cultured hepatoma cells
-
Jastreboff MM, Kedzierska B, Rode W: Altered thymidylate synthase in 5-fluorodeoxyuridine-resistant cultured hepatoma cells. Biochem Pharmacol 32:2259-2267, 1983
-
(1983)
Biochem Pharmacol
, vol.32
, pp. 2259-2267
-
-
Jastreboff, M.M.1
Kedzierska, B.2
Rode, W.3
-
5
-
-
0025307988
-
Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase
-
Barbour KW, Berger SH, Berger FG: Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase. Mol Pharmacol 37:515-518, 1990
-
(1990)
Mol Pharmacol
, vol.37
, pp. 515-518
-
-
Barbour, K.W.1
Berger, S.H.2
Berger, F.G.3
-
6
-
-
0024237997
-
Mechanisms for cisplatin-FUra synergism and cisplatin resistance in human ovarian carcinoma cells both in vitro and in vivo
-
Scanlon, KJ Lu Y, Kashani-Sabet M, et al: Mechanisms for cisplatin-FUra synergism and cisplatin resistance in human ovarian carcinoma cells both in vitro and in vivo. Adv Exp Med Biol 244:127-135, 1988
-
(1988)
Adv Exp Med Biol
, vol.244
, pp. 127-135
-
-
Scanlon, K.J.1
Lu, Y.2
Kashani-Sabet, M.3
-
7
-
-
0020067869
-
Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity
-
Washtien WL: Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity. Mol Pharmacol 21:723-728, 1982
-
(1982)
Mol Pharmacol
, vol.21
, pp. 723-728
-
-
Washtien, W.L.1
-
8
-
-
0022344622
-
Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistam human cells
-
Berger SH, Jenh CH, Johnson LF, et al: Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistam human cells. Mol Pharmacol 28:461-467, 1985
-
(1985)
Mol Pharmacol
, vol.28
, pp. 461-467
-
-
Berger, S.H.1
Jenh, C.H.2
Johnson, L.F.3
-
9
-
-
0024413739
-
Fluorouracil and high dose leucovorin in previously treated patients with metastatic breast cancer
-
Swain SM, Lippman ME, Egan EF, et al: Fluorouracil and high dose leucovorin in previously treated patients with metastatic breast cancer. J Clin Oncol 7:890-899, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 890-899
-
-
Swain, S.M.1
Lippman, M.E.2
Egan, E.F.3
-
10
-
-
0026030052
-
Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer
-
Chu E, Drake JC, Koeller DM, et al: Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer. Mol Pharmacol 39:136-143, 1991
-
(1991)
Mol Pharmacol
, vol.39
, pp. 136-143
-
-
Chu, E.1
Drake, J.C.2
Koeller, D.M.3
-
11
-
-
0028019880
-
Thymidylate synthase inhibition after administration of 5-fluorouracil with or without leucovorin; Implications for treatment with 5-fluorouracil
-
Peters GJ, Van der Wilt CL, Van Groeningen CJ, et al: Thymidylate synthase inhibition after administration of 5-fluorouracil with or without leucovorin; Implications for treatment with 5-fluorouracil. J Clin Oncol 12:2035-2042, 1995
-
(1995)
J Clin Oncol
, vol.12
, pp. 2035-2042
-
-
Peters, G.J.1
Van Der Wilt, C.L.2
Van Groeningen, C.J.3
-
12
-
-
0028151449
-
The role of thymidylate synthase expression in the prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, et al: The role of thymidylate synthase expression in the prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12:2640-2647, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
-
13
-
-
0020056302
-
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and - Resistant murine colon adenocarcinomas
-
Spears CP, Shahanian AH, Moran RG, et al: In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and - resistant murine colon adenocarcinomas. Cancer Res 42:450-456, 1982
-
(1982)
Cancer Res
, vol.42
, pp. 450-456
-
-
Spears, C.P.1
Shahanian, A.H.2
Moran, R.G.3
-
14
-
-
84871465584
-
-
New York, NY, Wiley
-
Rustum YM, Madajewicz S, Campbell J, et al: The Current Status of 5-Fluorouracil-Leucovorin Calcium Combination. New York, NY, Wiley, 1984, pp 77-82
-
(1984)
The Current Status of 5-Fluorouracil-Leucovorin Calcium Combination
, pp. 77-82
-
-
Rustum, Y.M.1
Madajewicz, S.2
Campbell, J.3
-
15
-
-
0025122061
-
The polymerase chain reaction: A new method of using molecular genetics for medical diagnosis
-
Eisenstein BI: The polymerase chain reaction: A new method of using molecular genetics for medical diagnosis. N Engl J Med 322:181-183, 1990
-
(1990)
N Engl J Med
, vol.322
, pp. 181-183
-
-
Eisenstein, B.I.1
-
16
-
-
0026560328
-
Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction
-
Horikoshi T, Danenberg KD, Stadibauer THW, et al: Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. Cancer Res 52:108-116, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 108-116
-
-
Horikoshi, T.1
Danenberg, K.D.2
Stadibauer, T.H.W.3
-
17
-
-
0020691434
-
Unstable methotrexate resistance in human small cell carcinoma associated with double minute chromosomes
-
Curt GA, Carney DN, Cowan KH, et al: Unstable methotrexate resistance in human small cell carcinoma associated with double minute chromosomes. N Engl J Med 308:199-202, 1983
-
(1983)
N Engl J Med
, vol.308
, pp. 199-202
-
-
Curt, G.A.1
Carney, D.N.2
Cowan, K.H.3
-
18
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, et al: Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 55:1407-1412, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
-
19
-
-
0024312584
-
Cancer of the Esophagus: The Wayne State University Experience: Perspective of a medical oncologist
-
Leichman L: Cancer of the Esophagus: The Wayne State University Experience: Perspective of a medical oncologist. Invest New Drugs 7:91-100, 1989
-
(1989)
Invest New Drugs
, vol.7
, pp. 91-100
-
-
Leichman, L.1
-
20
-
-
0027217550
-
Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma: A report of surgical morbidity
-
Shumate CR, Rich TA, Skibber JM, et al: Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma: A report of surgical morbidity. Cancer 71:3690-3693, 1993
-
(1993)
Cancer
, vol.71
, pp. 3690-3693
-
-
Shumate, C.R.1
Rich, T.A.2
Skibber, J.M.3
-
22
-
-
9044244450
-
The concept of neoadjuvant chemotherapy
-
Salmon SE (ed): Orlando, FL, Grune & Stratton
-
Frei A III, Clark JR, Miller D: The concept of neoadjuvant chemotherapy, in Salmon SE (ed): Adjuvant Therapy of Cancer V. Orlando, FL, Grune & Stratton, 1987, p 67-75
-
(1987)
Adjuvant Therapy of Cancer V
, pp. 67-75
-
-
Frei III, A.1
Clark, J.R.2
Miller, D.3
-
23
-
-
0027093714
-
Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: A University of Southern California pilot program
-
Leichman L, Silberman H, Leichman CG, et al: Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: A University of Southern California pilot program. J Clin Oncol 10:1933-1942, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1933-1942
-
-
Leichman, L.1
Silberman, H.2
Leichman, C.G.3
-
24
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
25
-
-
0022431983
-
Nucleotide sequence of a functional cDNA for human thymidylate synthase
-
Takeishi K, Kaneda S, Ayusawa D, et al: Nucleotide sequence of a functional cDNA for human thymidylate synthase. Nucleic Acid Res 13:2035-2045, 1987
-
(1987)
Nucleic Acid Res
, vol.13
, pp. 2035-2045
-
-
Takeishi, K.1
Kaneda, S.2
Ayusawa, D.3
-
26
-
-
0022261138
-
Evolution of the functional human B-actin gene and its multipseudogene family conservation of non-coding regions and chromosomal dispersion of pseudogenes
-
Ng SY, Gunning P, Eddy R, et al: Evolution of the functional human B-actin gene and its multipseudogene family conservation of non-coding regions and chromosomal dispersion of pseudogenes. Mol Cell Biol 5:2720-2732, 1985
-
(1985)
Mol Cell Biol
, vol.5
, pp. 2720-2732
-
-
Ng, S.Y.1
Gunning, P.2
Eddy, R.3
-
27
-
-
84871467339
-
Effect of p53 activity on the cytotoxicity of 5-fluoro-2′deoxyuridine and its inhibition of thymidylate synthase
-
abstr 121
-
Lenz HJ, Ju JF, Danenberg KD, et al: Effect of p53 activity on the cytotoxicity of 5-fluoro-2′deoxyuridine and its inhibition of thymidylate synthase. Proc Am Assoc Caner Res 36:21, 1995 (abstr 121)
-
(1995)
Proc Am Assoc Caner Res
, vol.36
, pp. 21
-
-
Lenz, H.J.1
Ju, J.F.2
Danenberg, K.D.3
|