Human RNase H-mediated RNA cleavage from DNA-RNA duplexes is inhibited by 6-deoxythioguanosine incorporation into DNA

Molecular Pharmacology

Volumn 56, Issue 4, 1999, Pages 841-848

  Krynetskaia, Natalia F ^a,b   Krynetski, Eugene Y ^a   Evans, William E ^a,c  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; CELL DNA; DEOXYTHIOGUANOSINE; MERCAPTOPURINE; RIBONUCLEASE H; RNA; TIOGUANINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA DRUG COMPLEX; DNA REPLICATION; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOLECULAR INTERACTION; PRIORITY JOURNAL; RNA CLEAVAGE;

CELL SURVIVAL; DEOXYGUANOSINE; DNA REPLICATION; DNA, NEOPLASM; HUMANS; HYDROLYSIS; NUCLEIC ACID HETERODUPLEXES; RIBONUCLEASE H, CALF THYMUS; RNA, NEOPLASM; SUBSTRATE SPECIFICITY; THIONUCLEOSIDES; TUMOR CELLS, CULTURED;

EID: 0032851120     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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