-
1
-
-
0025331198
-
Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
-
Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM: Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 336:225, 1990
-
(1990)
Lancet
, vol.336
, pp. 225
-
-
Lennard, L.1
Lilleyman, J.S.2
Van Loon, J.3
Weinshilboum, R.M.4
-
2
-
-
0028860142
-
Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy. Nordic Society for Pediatric Hematology and Oncology
-
Schmiegelow K, Schroder H, Gustafsson G, Kristinsson J, Glomstein A, Salmi T, Wranne L, Schroder H: Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy. Nordic Society for Pediatric Hematology and Oncology. J Clin Oncol 13:345, 1995
-
(1995)
J Clin Oncol
, vol.13
, pp. 345
-
-
Schmiegelow, K.1
Schroder, H.2
Gustafsson, G.3
Kristinsson, J.4
Glomstein, A.5
Salmi, T.6
Wranne, L.7
Schroder, H.8
-
3
-
-
0026443245
-
Red blood cell methotrexate and folate levels in children with acute lymphoblastic leukemia undergoing therapy: A Pediatric Oncology Group pilot study
-
Graham ML, Shuster JJ, Kamen BA, Cheo DL, Harrison MP, Leventhal BG, Pullen DJ, Whitehead VM: Red blood cell methotrexate and folate levels in children with acute lymphoblastic leukemia undergoing therapy: A Pediatric Oncology Group pilot study. Cancer Chemother Pharmacol 31:217, 1992
-
(1992)
Cancer Chemother Pharmacol
, vol.31
, pp. 217
-
-
Graham, M.L.1
Shuster, J.J.2
Kamen, B.A.3
Cheo, D.L.4
Harrison, M.P.5
Leventhal, B.G.6
Pullen, D.J.7
Whitehead, V.M.8
-
4
-
-
0028269944
-
Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia
-
Lilleyman JS, Lennard L: Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia. Lancet 343:1188, 1994
-
(1994)
Lancet
, vol.343
, pp. 1188
-
-
Lilleyman, J.S.1
Lennard, L.2
-
5
-
-
0032545976
-
Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia
-
Evans WE, Relling MV, Rodman JH, Crom WR, Boyett JM, Pui CH: Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia. N Engl J Med 338:499, 1998
-
(1998)
N Engl J Med
, vol.338
, pp. 499
-
-
Evans, W.E.1
Relling, M.V.2
Rodman, J.H.3
Crom, W.R.4
Boyett, J.M.5
Pui, C.H.6
-
6
-
-
0023588197
-
Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells
-
Lennard L: Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells. J Chromatogr 423:169, 1987
-
(1987)
J Chromatogr
, vol.423
, pp. 169
-
-
Lennard, L.1
-
7
-
-
0026465403
-
High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: Quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample
-
Lennard L, Singleton HJ: High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: Quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample. J Chromatogr 583:83, 1992
-
(1992)
J Chromatogr
, vol.583
, pp. 83
-
-
Lennard, L.1
Singleton, H.J.2
-
8
-
-
0028063423
-
Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
-
Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui C-H, Evans WE: Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. J Clin Invest 94:1996, 1994
-
(1994)
J Clin Invest
, vol.94
, pp. 1996
-
-
Synold, T.W.1
Relling, M.V.2
Boyett, J.M.3
Rivera, G.K.4
Sandlund, J.T.5
Mahmoud, H.6
Crist, W.M.7
Pui, C.-H.8
Evans, W.E.9
-
9
-
-
0028044714
-
Thiopurine methyltransferase activity in American white subjects and black subjects
-
McLeod HL, Lin JS, Scott EP, Pui C-H, Evans WE: Thiopurine methyltransferase activity in American white subjects and black subjects. Clin Pharmacol Ther 55:15, 1994
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 15
-
-
McLeod, H.L.1
Lin, J.S.2
Scott, E.P.3
Pui, C.-H.4
Evans, W.E.5
-
10
-
-
0030934850
-
Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
-
Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui C-H, Relling MV, Evans WE: Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 126:608, 1997
-
(1997)
Ann Intern Med
, vol.126
, pp. 608
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
Fessing, M.Y.4
Tai, H.L.5
Pui, C.-H.6
Relling, M.V.7
Evans, W.E.8
-
11
-
-
0025837127
-
Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
-
Evans WE, Horner M, Chu YQ, Kalwinsky D, Roberts WM: Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia. J Pediatr 119:985, 1991
-
(1991)
J Pediatr
, vol.119
, pp. 985
-
-
Evans, W.E.1
Horner, M.2
Chu, Y.Q.3
Kalwinsky, D.4
Roberts, W.M.5
-
12
-
-
0000336139
-
Regression models and life tables
-
Cox DR: Regression models and life tables. J R Stat Soc B34:187, 1972
-
(1972)
J R Stat Soc
, vol.B34
, pp. 187
-
-
Cox, D.R.1
-
13
-
-
0003496954
-
-
New York, NY, Wiley
-
Kalbfleisch JD, Prentice RL: Statistical Analysis of Failure Time Data. New York, NY, Wiley, 1980, p 84
-
(1980)
Statistical Analysis of Failure Time Data
, pp. 84
-
-
Kalbfleisch, J.D.1
Prentice, R.L.2
-
14
-
-
0344766208
-
Importance of 6-mercaptopurine dose in lymphoblastic leukaemia
-
Hale JP, Lilleyman JS: Importance of 6-mercaptopurine dose in lymphoblastic leukaemia. Arch Dis Child 64:164, 1991
-
(1991)
Arch Dis Child
, vol.64
, pp. 164
-
-
Hale, J.P.1
Lilleyman, J.S.2
-
15
-
-
0025838273
-
Prognostic significance of methotrexate and 6-mercaptopurine dosage during maintenance chemotherapy for childhood acute lymphoblastic leukemia
-
Schmiegelow K: Prognostic significance of methotrexate and 6-mercaptopurine dosage during maintenance chemotherapy for childhood acute lymphoblastic leukemia. Pediatr Hematol Oncol 8:301, 1991
-
(1991)
Pediatr Hematol Oncol
, vol.8
, pp. 301
-
-
Schmiegelow, K.1
-
16
-
-
0028238236
-
6-Mercaptopurine cumulative dose: A critical factor of maintenance therapy in average risk childhood acute lymphoblastic leukemia
-
Dibenedetto SP, Guardabasso V, Ragusa R, Di Cataldo A, Miraglia V, D'Amico S, Ippolito AM: 6-Mercaptopurine cumulative dose: A critical factor of maintenance therapy in average risk childhood acute lymphoblastic leukemia. Pediatr Hematol Oncol 11:251, 1994
-
(1994)
Pediatr Hematol Oncol
, vol.11
, pp. 251
-
-
Dibenedetto, S.P.1
Guardabasso, V.2
Ragusa, R.3
Di Cataldo, A.4
Miraglia, V.5
D'Amico, S.6
Ippolito, A.M.7
-
17
-
-
0000389279
-
The purine path to chemotherapy
-
Elion GB: The purine path to chemotherapy. Science 24:441, 1989
-
(1989)
Science
, vol.24
, pp. 441
-
-
Elion, G.B.1
-
18
-
-
0025242868
-
Maintenance chemotherapy for childhood acute lymphoblastic leukemia: Should dosage be guided by white blood cell counts?
-
Schmiegelow K, Pulczynska MK: Maintenance chemotherapy for childhood acute lymphoblastic leukemia: Should dosage be guided by white blood cell counts? Am J Pediatr Hematol Oncol 12:462, 1990
-
(1990)
Am J Pediatr Hematol Oncol
, vol.12
, pp. 462
-
-
Schmiegelow, K.1
Pulczynska, M.K.2
-
19
-
-
0026716028
-
Relapse in acute lymphoblastic leukemia as a function of white blood cell and absolute neutrophil counts during maintenance chemotherapy
-
Lucas K, Gula MJ, Blatt J: Relapse in acute lymphoblastic leukemia as a function of white blood cell and absolute neutrophil counts during maintenance chemotherapy. Pediatr Hematol Oncol 9:91, 1992
-
(1992)
Pediatr Hematol Oncol
, vol.9
, pp. 91
-
-
Lucas, K.1
Gula, M.J.2
Blatt, J.3
-
20
-
-
0029931874
-
6-Mercaptopurine dose escalation and its effect on drug tolerance in childhood lymphoblastic leukaemia
-
Welch JC, Lilleyman JS: 6-Mercaptopurine dose escalation and its effect on drug tolerance in childhood lymphoblastic leukaemia. Cancer Chemother Pharmacol 38:113, 1996
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, pp. 113
-
-
Welch, J.C.1
Lilleyman, J.S.2
-
21
-
-
0030825783
-
Continuing (maintenance) therapy in lymphoblastic leukaemia: Lessons from MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia
-
Chessells JM, Harrison G, Lilleyman JS, Bailey CC, Richards SM: Continuing (maintenance) therapy in lymphoblastic leukaemia: Lessons from MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia. Br J Haematol 98:945, 1997
-
(1997)
Br J Haematol
, vol.98
, pp. 945
-
-
Chessells, J.M.1
Harrison, G.2
Lilleyman, J.S.3
Bailey, C.C.4
Richards, S.M.5
-
22
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum RM, Sladek SL: Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 32:651, 1980
-
(1980)
Am J Hum Genet
, vol.32
, pp. 651
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
23
-
-
0030802914
-
Thiopurine methyltransferase deficiency in childhood lymphoblastic leukaemia: 6-mercaptopurine dosage strategies
-
Lennard L, Lewis IJ, Michelagnoli M, Lilleyman JS: Thiopurine methyltransferase deficiency in childhood lymphoblastic leukaemia: 6-mercaptopurine dosage strategies. Med Pediatr Oncol 29:252, 1997
-
(1997)
Med Pediatr Oncol
, vol.29
, pp. 252
-
-
Lennard, L.1
Lewis, I.J.2
Michelagnoli, M.3
Lilleyman, J.S.4
-
24
-
-
0031933720
-
Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency
-
Andersen JB, Szumlanski C, Weinshilboum RM, Schmiegelow K: Pharmacokinetics, dose adjustments, and 6-mercaptopurine/ methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency. Acta Paediatr 87:108, 1998
-
(1998)
Acta Paediatr
, vol.87
, pp. 108
-
-
Andersen, J.B.1
Szumlanski, C.2
Weinshilboum, R.M.3
Schmiegelow, K.4
|