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Volumn 63, Issue 1, 1998, Pages 11-16

Pharmacogenetics of cancer therapy: Getting personal

Author keywords

[No Author keywords available]

Indexed keywords

AMONAFIDE; AZATHIOPRINE; BUSULFAN; CYCLOPHOSPHAMIDE; FLUOROURACIL; IRINOTECAN; MERCAPTOPURINE; TIOGUANINE;

EID: 0032231751     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/301941     Document Type: Article
Times cited : (116)

References (37)
  • 1
    • 0030758131 scopus 로고    scopus 로고
    • Identification of the polymorphically expressed CYP2C19 and the wild type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosphamide activation
    • Chang TK, Yu L, Goldstein JA, Waxman DJ (1997) Identification of the polymorphically expressed CYP2C19 and the wild type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosphamide activation. Pharmacogenetics 7:211-221
    • (1997) Pharmacogenetics , vol.7 , pp. 211-221
    • Chang, T.K.1    Yu, L.2    Goldstein, J.A.3    Waxman, D.J.4
  • 2
    • 0026717661 scopus 로고
    • The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients
    • Chocair PR, Duley JA, Simmonds HA, Cameron JS (1992) The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients. Transplantation 53:1051-1056
    • (1992) Transplantation , vol.53 , pp. 1051-1056
    • Chocair, P.R.1    Duley, J.A.2    Simmonds, H.A.3    Cameron, J.S.4
  • 3
    • 0029840656 scopus 로고    scopus 로고
    • Busulfan conjugation by glutathione S-transferases alpha, mu and pi
    • Czerwinski M, Gibbs JP, Slattery JT (1996) Busulfan conjugation by glutathione S-transferases alpha, mu and pi. Drug Metab Dispos 24:1015-1019
    • (1996) Drug Metab Dispos , vol.24 , pp. 1015-1019
    • Czerwinski, M.1    Gibbs, J.P.2    Slattery, J.T.3
  • 4
    • 0023902287 scopus 로고
    • Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity
    • Diasio RB, Beavers TL, Carpenter JT (1988) Familial deficiency of dihydropyrimidine dehydrogenase: biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. J Clin Invest 81:47-51
    • (1988) J Clin Invest , vol.81 , pp. 47-51
    • Diasio, R.B.1    Beavers, T.L.2    Carpenter, J.T.3
  • 5
    • 0024554561 scopus 로고
    • The purine path to chemotherapy
    • Elion GB (1989) The purine path to chemotherapy. Science 244:41-47
    • (1989) Science , vol.244 , pp. 41-47
    • Elion, G.B.1
  • 6
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • Evans WE, Horner M, Chu YQ, Kalwinsky D, Roberts WM (1991) Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia. J Pediatr 119:985-989
    • (1991) J Pediatr , vol.119 , pp. 985-989
    • Evans, W.E.1    Horner, M.2    Chu, Y.Q.3    Kalwinsky, D.4    Roberts, W.M.5
  • 7
    • 0029133354 scopus 로고
    • Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency
    • Gonzalez FJ, Fernandez-Salguero P (1995) Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency. Trends Pharmacol Sci 16: 325-327
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 325-327
    • Gonzalez, F.J.1    Fernandez-Salguero, P.2
  • 8
    • 0027476961 scopus 로고
    • Molecular genetics of the N-acetyltransferases
    • Grant DM (1993) Molecular genetics of the N-acetyltransferases. Pharmacogenetics 3:45-50
    • (1993) Pharmacogenetics , vol.3 , pp. 45-50
    • Grant, D.M.1
  • 9
    • 0032231725 scopus 로고    scopus 로고
    • Nm23-H1: Genetic alterations and expression patterns in tumor metastasis
    • in this issue
    • Hartsough MT, Steeg PS (1998) Nm23-H1: genetic alterations and expression patterns in tumor metastasis. Am J Hum Genet 63:6-10 (in this issue)
    • (1998) Am J Hum Genet , vol.63 , pp. 6-10
    • Hartsough, M.T.1    Steeg, P.S.2
  • 11
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT-11): Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer L, King CD, Whitington PF, Green MD, Roy SK, Tephly TR, Coffman BL, et al (1998) Genetic predisposition to the metabolism of irinotecan (CPT-11): role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest 101:847-854
    • (1998) J Clin Invest , vol.101 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3    Green, M.D.4    Roy, S.K.5    Tephly, T.R.6    Coffman, B.L.7
  • 14
    • 0022551875 scopus 로고
    • Oral 6-mercaptopurine in childhood leukemia: Parent drug pharmacokinetics and active metabolite concentrations
    • Lennard L, Keen D, Lilleyman JS (1986) Oral 6-mercaptopurine in childhood leukemia: parent drug pharmacokinetics and active metabolite concentrations. Clin Pharmacol Ther 40:287-292
    • (1986) Clin Pharmacol Ther , vol.40 , pp. 287-292
    • Lennard, L.1    Keen, D.2    Lilleyman, J.S.3
  • 15
    • 0024818659 scopus 로고
    • Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia
    • Erratum [1990] J Clin Oncol 8:567
    • Lennard L, Lilleyman JS (1989) Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia. J Clin Oncol 7:1816-1823 (Erratum [1990] J Clin Oncol 8:567)
    • (1989) J Clin Oncol , vol.7 , pp. 1816-1823
    • Lennard, L.1    Lilleyman, J.S.2
  • 16
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
    • Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM (1990) Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 336: 225-229
    • (1990) Lancet , vol.336 , pp. 225-229
    • Lennard, L.1    Lilleyman, J.S.2    Van Loon, J.3    Weinshilboum, R.M.4
  • 17
    • 0028044714 scopus 로고
    • Thiopurine methyltransferase activity in American white subjects and black subjects
    • McLeod HL, Lin JS, Scott EP, Pui CH, Evans WE (1994) Thiopurine methyltransferase activity in American white subjects and black subjects. Clin Pharmacol Ther 55:15-20
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 15-20
    • McLeod, H.L.1    Lin, J.S.2    Scott, E.P.3    Pui, C.H.4    Evans, W.E.5
  • 18
    • 0027285234 scopus 로고
    • Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • McLeod HL, Miller DR, Evans WE (1993) Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient. Lancet 341:1151
    • (1993) Lancet , vol.341 , pp. 1151
    • McLeod, H.L.1    Miller, D.R.2    Evans, W.E.3
  • 19
    • 0028930908 scopus 로고
    • Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia
    • McLeod HL, Relling MV, Liu Q, Pui CH, Evans WE (1995) Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia. Blood 85:1897-1902
    • (1995) Blood , vol.85 , pp. 1897-1902
    • McLeod, H.L.1    Relling, M.V.2    Liu, Q.3    Pui, C.H.4    Evans, W.E.5
  • 20
    • 0030995879 scopus 로고    scopus 로고
    • Molecular mechanisms of genetic polymorphisms of drug metabolism
    • Meyer UA, Zanger UM (1997) Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu Rev Pharmacol Toxicol 37:269-296
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 269-296
    • Meyer, U.A.1    Zanger, U.M.2
  • 21
    • 0032231452 scopus 로고    scopus 로고
    • Host susceptibility to cancer progression
    • in this issue
    • Narod SA (1998) Host susceptibility to cancer progression. Am J Hum Genet 63:1-5 (in this issue)
    • (1998) Am J Hum Genet , vol.63 , pp. 1-5
    • Narod, S.A.1
  • 22
    • 0031035007 scopus 로고    scopus 로고
    • Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?
    • Nebert DW (1997) Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist? Am J Hum Genet 60:265-271
    • (1997) Am J Hum Genet , vol.60 , pp. 265-271
    • Nebert, D.W.1
  • 23
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • Nebert DW, McKinnon RA, Puga A (1996) Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol 15:273-280
    • (1996) DNA Cell Biol , vol.15 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 26
    • 0027401302 scopus 로고
    • Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • Schutz E, Gummert J, Mohr F, Oellerich M (1993) Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient. Lancet 341:436
    • (1993) Lancet , vol.341 , pp. 436
    • Schutz, E.1    Gummert, J.2    Mohr, F.3    Oellerich, M.4
  • 27
    • 0026907122 scopus 로고
    • Human liver thiopurine methyltransferase pharmacogenetics: Biochemical properties, liver-erythrocyte correlation and presence of isozymes
    • Szumlanski CL, Honchel R, Scott MC, Weinshilboum RM (1992) Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes. Pharmacogenetics 2: 148-159
    • (1992) Pharmacogenetics , vol.2 , pp. 148-159
    • Szumlanski, C.L.1    Honchel, R.2    Scott, M.C.3    Weinshilboum, R.M.4
  • 28
    • 0030048791 scopus 로고    scopus 로고
    • Thiopurine methyltransferase pharmacogenetics: Human gene cloning and characterization of a common polymorphism
    • Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, Spurr N, et al (1996) Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism. DNA Cell Biol 15:17-30
    • (1996) DNA Cell Biol , vol.15 , pp. 17-30
    • Szumlanski, C.1    Otterness, D.2    Her, C.3    Lee, D.4    Brandriff, B.5    Kelsell, D.6    Spurr, N.7
  • 29
    • 0030986251 scopus 로고    scopus 로고
    • Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
    • Tai HL, Krynetski EY, Schuetz EG, Yanishevski Y, Evans WE (1997) Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity. Proc Natl Acad Sci USA 94: 6444-6449
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6444-6449
    • Tai, H.L.1    Krynetski, E.Y.2    Schuetz, E.G.3    Yanishevski, Y.4    Evans, W.E.5
  • 30
    • 0029919807 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase deficiency: Two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians
    • Tai H-L, Krynetski EY, Yates CR, Loennechen T, Fessing MY, Krynetskaia NF, Evans WE (1996) Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians. Am J Hum Genet 58:694-702
    • (1996) Am J Hum Genet , vol.58 , pp. 694-702
    • Tai, H.-L.1    Krynetski, E.Y.2    Yates, C.R.3    Loennechen, T.4    Fessing, M.Y.5    Krynetskaia, N.F.6    Evans, W.E.7
  • 31
    • 0026779179 scopus 로고
    • Human kidney thiopurine methyltransferase: Photoaffinity labeling with S-adenosyl-L-methionine
    • Van Loon JA, Szumlanski CL, Weinshilboum RM (1992) Human kidney thiopurine methyltransferase: photoaffinity labeling with S-adenosyl-L-methionine. Biochem Pharmacol 44:775-785
    • (1992) Biochem Pharmacol , vol.44 , pp. 775-785
    • Van Loon, J.A.1    Szumlanski, C.L.2    Weinshilboum, R.M.3
  • 32
    • 0019987157 scopus 로고
    • Thiopurine methyltransferase biochemical genetics: Human lymphocyte activity
    • Van Loon JA, Weinshilboum RM (1982) Thiopurine methyltransferase biochemical genetics: human lymphocyte activity. Biochem Genet 20:637-658
    • (1982) Biochem Genet , vol.20 , pp. 637-658
    • Van Loon, J.A.1    Weinshilboum, R.M.2
  • 33
    • 0029973215 scopus 로고    scopus 로고
    • Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity
    • Wei X, McLeod HL, McMurrough J, Gonzalez FJ, Fernandez-Salguero P (1996) Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. J Clin Invest 98:610-615
    • (1996) J Clin Invest , vol.98 , pp. 610-615
    • Wei, X.1    McLeod, H.L.2    McMurrough, J.3    Gonzalez, F.J.4    Fernandez-Salguero, P.5
  • 34
    • 0017880983 scopus 로고
    • Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
    • Weinshilboum RM, Raymond FA, Pazmino PA (1978) Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 85: 323-333
    • (1978) Clin Chim Acta , vol.85 , pp. 323-333
    • Weinshilboum, R.M.1    Raymond, F.A.2    Pazmino, P.A.3
  • 35
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL (1980) Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 32: 651-662
    • (1980) Am J Hum Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 36
    • 0019956940 scopus 로고
    • Pharmacogenetics of human thiopurine methyltransferase: Kidney-erythrocyte correlation and immunotitration studies
    • Woodson LC, Dunnette JH, Weinshilboum RM (1982) Pharmacogenetics of human thiopurine methyltransferase: kidney-erythrocyte correlation and immunotitration studies. J Pharmacol Exp Ther 222:174-181
    • (1982) J Pharmacol Exp Ther , vol.222 , pp. 174-181
    • Woodson, L.C.1    Dunnette, J.H.2    Weinshilboum, R.M.3
  • 37
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui CH, Relling MV, et al (1997) Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 126:608-614
    • (1997) Ann Intern Med , vol.126 , pp. 608-614
    • Yates, C.R.1    Krynetski, E.Y.2    Loennechen, T.3    Fessing, M.Y.4    Tai, H.L.5    Pui, C.H.6    Relling, M.V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.