Evidence for grape, wine and tea polyphenols as modulators of atherosclerosis and ischemic heart disease in humans

Journal of Nutraceuticals, Functional and Medical Foods

Volumn 3, Issue 3, 2001, Pages 67-93

  Dubick, M A ^a   Omaye, S T ^a  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Flavonoids; Grapes; Hemostasis; Humans; Ischemic heart disease; LDL oxidation; Polyphenols; Tea; Wine

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; POLYPHENOL DERIVATIVE;

ANTIOXIDANT ACTIVITY; ATHEROSCLEROSIS; BLOOD CLOTTING; CARDIOVASCULAR RISK; GRAPE; HEART PROTECTION; HUMAN; ISCHEMIC HEART DISEASE; LIPID OXIDATION; LIPOPROTEIN BLOOD LEVEL; REVIEW; TEA; THROMBOCYTE AGGREGATION; VASODILATATION; WINE;

ANIMALIA; VITACEAE; VITIS SP.; VITIS VINIFERA;

EID: 0035196999     PISSN: 10894179     EISSN: None     Source Type: Journal    
DOI: 10.1300/J133v03n03_04     Document Type: Review

References (168)

1. Effects of beer, wine, and liquor in coronary deaths
2. Relationship of dietary intake to subsequent coronary heart disease incidence: The Puerto Rico heart health program
3. Diet, alcohol and coronary heart disease in men
4. Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine
5. Alcohol and ischemic heart disease: Wine, beer or both
6. Alcohol consumption, serum low density lipoprotein cholesterol concentration, and risk of ischaemic heart disease: Six year follow up in the Copenhagen male study
7. Red wine, white wine, liquor, beer and risk for coronary artery disease hospitalization
8. Heath implications of mediterranean diets in light of contemporary knowledge. 2. Meat, wine, fats and oils
9. Alcohol. Lipid metabolism and coronary heart disease
10. Alcohol comsumption, S-LDL-cholesterol and risk of heart disease. 6-year follow-up in the Copenhagen male study
11. Moderate drinking and cardiovascular health
12. Moderate alcohol consumption and risk for angina pectoris or myocardial infarction in U.S. male physicians
13. Mortality associated with moderate intakes of wine, beer, or spirits
14. Follow up study of moderate alcohol intake and mortality among middle aged men in Shanghai, China
15. Mortality in relation to consumption of alcohol: 13 Years observations on male British doctors
16. Alcohol, ischemic heart disease, and the French paradox
17. Alcohol and blood lipids. The cooperative lipoprotein phenotyping study
18. Alcohol consumption and high density lipoprotein cholesterol in marathon runners
19. Short-term effect of moderate alcohol consumption on lipid metabolism and energy balance in normal men. Metabolism
20. Alcohol and preoperative management
21. Wine, alcohol, platelets, and the French paradox for coronary heart disease
22. Diet quality and dietary diversity in France: Implications for the French paradox
23. The French paradox: Vegetables or wine
24. Does diet or alcohol explain the French paradox
25. Wine consumption and other dietary variables in males under 60 before and after acute myocardial infarction
26. Explaining the French paradox
27. Why heart disease mortality is low in France: The time lag explanation
28. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study
29. Dietary flavonoids, antioxidant vitamins, and incidence of stroke
30. Flavonoid intake and coronary mortality in Finland: A cohort story
31. Tea consumption, relationship to cholesterol, blood pressure, and coronary and total mortality
32. Coffee and tea intake and the risk of myocardial infarction
33. Tea flavonoids may protect against atherosclerosis
34. Coffee and tea consumption and the prevalence of coronary heart disease in men and women: Results from the Scottish health study
35. Apolipoprotein E genotype modulates the effect of black tea drinking on blood lipids and blood coagulation factors: A pilot study
36. When wine is red
37. Polyphenols in our diet: Do they matter
38. Does wine work?
39. Tea flavonols in cardiovascular disease and cancer epidemiology
40. Bioactive ingredients: Antioxidants and polyphenols in tea
41. Characteristics and occurrence of phenolic phytochemicals
42. The chemistry and biological effects of flavonoids and phenolic acids
43. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significane
44. Analysis of antioxidant wine polyphenols by gas chromatography-mass spectromety
45. Antioxidant polyhenols in tea, cocoa, and wine
46. Wine as a biological fluid: History, production, and role in disease prevention
47. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices
48. Grape extracts inhibit lipid peroxidation of human low density lipoprotein
49. Principal phenolic phytochemicals in selected California wines and their antioxidant activity in inhibiting oxidation of human low-density lipoproteins
50. Inhibition of human LDL oxidation by resveratrol
51. Resveratrol is a selective human cytochrome P450 1A1 inhibitor
52. Modification of atherogenis and heart disease by grape wine and tea polyphenols
53. Polyphenols produced during red wine ageing
54. Cardioprotection of red wine: Role of polyphenolic antioxidants
55. Green tea polyphenols and cancer: Biologic mechanisms and practical implications
56. Green tea composition, consumption, and polyphenol chemistry
57. Inhibitory effect of tea catechins on collagenase activity
58. Analysis of tea polyphenols
59. Lignan and isoflavonoid concentrations in tea and coffee
60. Tea and health
61. Preclinical efficacy studies of green and black tea extracts
62. The Flavonoids. A class of semi-essential food components: Their role in human nutrition
63. Dietary intake and bioavailability of polyphenols
64. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands
65. Quercetin
66. Tea and health
67. The identification of flavonoids as glycosides in human plasma
68. Analysis of plasma and urinary tea polyphenols in human subjects
69. Catechin in human plasma after ingestion of a single serving of reconstituted red wine
70. Metabolism of flavonoid compounds in germ-free rats
71. Degradation of polyphenolic (catechin and tannic acid) in the rat intestinal tract. Effect on colonic fermentation and faecal output
72. Bioavailability of catechins from tea: The effect of milk
73. Absorption and disposition kinetics of the dietary antioxidant quercetin in man
74. Application of new high-performance liquid chromatographic method for measuring selected polyphenols in human plasma
75. Epigallocatechin and epigallocatechin-3-gallate
76. Plasma and lipoprotein levels of tea catechins following repeated tea consumption
77. Disposition of quercetin in man after single oral and intravenous doses
78. Optimization of nutrition: Polyphenols and vascular protection
79. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study
80. Antioxidant flavonols and coronary heart disease risk
81. Relation between intake of flavonoids and risk for coronary heart disease in male health professionals
82. Antioxidant flavonols and ischemic heart disease in a Welsh population of men: The Caerphilly study
83. Effect of dietary supplementation of red or white wine on human blood chemistry, hematology and coagulation: Favorable effect of red wine on plasma high-density lipoprotein
84. Effect of red wine consumption on lipoprotein (a) and other risk factors for antherosclerosis
85. Lipoprotein[a]: A predictor of antherosclerotic disease
86. Wine: Does color count?
87. Green tea consumption and serum lipid profiles: A cross sectional study in Northern Kyushu
88. Coffee consumption and plasma total homosysteine: The Hordaland homocysteine study
89. Association of serum lipoproteins and health related habits with coffee and tea consumption in free-living subjects examined in the Israeli CORDIS study
90. Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants
91. Review of the biology of quercetin and related bioflavonoids
92. Resveratrol: A molecule whose time has come? And gone?
93. Structure-antioxidant activity relationships of flavonoids and phenolic acids
94. Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes loaded with α-linolenic acid
95. Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injiury
96. Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships
97. Antioxidant effect of red wine polyphenols on red blood cells
98. Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols
99. Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: Nitration or electron donation?
100. Dietary flavonoids and interaction with endogenous antioxidants
101. The effect of grape-skin extract on oxidative status
102. Structural aspects of antioxidant activity of flavonoids
103. Red wine and antioxidant activity in serum
104. Total antioxidant potential of Chilean wines
105. Antioxidant capacity and polyphenolic components of teas: Implications for altering in vivo antioxidants status
106. Protective role of black tea against oxidative damage of human red blood cells
107. Protective effects of green tea extract against reperfusion injury in rats: Antioxidant and anti-inflammatory properties
108. Tea phenols: Antioxidant effectiveness of teas, tea components, tea fractions and their binding with lipoproteins
109. Red wine, tea, and antioxidants
110. Effects of red and white wine on serum lipids, platelet aggregation, oxidation products and antioxidants: A preliminary report
111. Effect of red wine ingestion on the antioxidant capacity of serum
112. Black grape enhances plasma antioxidant potential
113. Red wine and black grape strengthen blood antioxidant potential
114. Consumption of red wine polyphenols reduces the susceptibility of low-density lipoproteins to oxidation in vivo
115. Alcohol-free red wine enhances plasma anitoxidant capacity in humans
116. Cardioprotective effect of red wine may be mediated by urate
117. Ingestion of red wine ignificantly increases plasma phenolic acid concentrations but does not acutely affect ex vivo lipoprotein oxidizability
118. Ascorbate and urate are the strongest determinants of plasma antioxidant capacity and serum lipid resistance to oxidation in Finnish men
119. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women
120. The effect of tea consumption on oxidative stress in smokers and non-smokers
121. Acute effects of ingestion of black and green tea on lipoprotein oxidation
122. Red wine effects on peroxidation indexes of rat plama and erythrocytes
123. Effect of tea flavonoid supplementation on the susceptibility of low-density lipoprotein to oxidative modification
124. White wine reduces the susceptibility of low-density lipoprotein to oxidation
125. Red wines inhibits the cell-mediated oxidation of LDL and HDL
126. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
127. Polyphenolic flavonoids inhibit macrophage-mediated oxidation of LDL and attenuate atherogenesis
128. Grape extract inhibits lipid peroxidation of human low density lipoprotein
129. Inhibition of human low-density lipoprotein oxidation by flavonoids in red wine and grape juice
130. Phenolic content of various beverages determines the extent of inhibition of human serum and low-density lipoprotein oxidation in vitro: Identification and mechanism of action of some cinnamic acid derivatives from red wine
131. Antioxidants in wine
132. Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein
133. Effect of the consumption of alcohol, white wine, and red wine on platelet function and serum lipid
134. Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation
135. Red wine consumption does not affect oxidizability of low-density lipoproteins in volunteers
136. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease
137. Antioxidant and prooxidant effects of ascorbic acid, dehydroascorbic acid and flavonoids on LDL submitted to different degrees of oxidation
138. The modification of low density lipoprotein by the flavonoids myricetin and gossypetin
139. Trace element and mineral concentrations in serum and aorta from patients with abdominal aneurysmal or occlusive disease
140. Administration of wine and grape juice inhibits in vivo patients activity and thrombosis in stenosed canine arteries
141. Moderate beer consumpution and the blood coagulation in patients with coronary artery disease
142. Effects of moderate consumption of red wine on platelet aggregation and haemostatic variables in healthy volunteers
143. Wines and grape juices as modulators of platelet aggregation in healthy human subjects
144. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
145. Grape juice, but not orange juice or grapefruit juice, inhibits human platelet aggregation
146. A study on tea-pigment in prevention of atherosclerosis
147. Tea drinking and haemostasis: A randomized, placebo-controlled, crossover study in free-living subjects
148. The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide
149. Endothelium-dependent vasorelaxing activity of wine and other grape products
150. Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action
151. Flavonoids as scavenger of nitric oxide radical
152. Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta
153. Take two glasses of wine and see me in the morning
154. Potential health impacts of excessive flavonoid intake
155. Side effects of flavonoids in medical practice
156. Flavonoids-chemistry, metabolism, cardiprotective effects, and dietary sources
157. Content of potentially anticarcinogenic flavonoids of tea infusions. Wines and fruit juices
158. Calcium, copper, iron, magnesium and zinc utilization of humans as affected by consumption of black, decaffinated black and green teas
159. Red wine consumption and gastric cancer in Portugal: A case-control study
160. Free radicals in red wine, but not in white?
161. The involvement of reactive oxygen species in the direct-acting mutagencity of wine
162. Antioxidant and prooxidant behavior of flavonoids: Structure-activity relationships
163. Antioxidant and pro-oxidant actions of flavonoids: Effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion
164. Phenolics: Prooxidants or antioxidants
165. Antioxidant and prooxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA
166. Moderate alcohol consumption and health
167. Epidemiology of the medical consequences of alcohol
168. The chemical pathogenesis of alcohol-induced tissue injury