Consumption of red wine polyphenols reduces the susceptibility of low- density lipoproteins to oxidation in vivo

American Journal of Clinical Nutrition

Volumn 68, Issue 2, 1998, Pages 258-265

  Nigdikar, Shailja V ^b   Williams, Norman R ^b   Griffin, Bruce A ^b   Howard, Alan N ^a  

^a Whitehill House   (United Kingdom)

^b NONE

Author keywords

Antioxidants Whitehill House, Granhams; LDL; Lipid peroxidation; Men; Polyphenols; Red wine; White wine

Indexed keywords

LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; POLYPHENOL DERIVATIVE;

ADULT; AGED; ALCOHOL CONSUMPTION; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; HUMAN; HUMAN EXPERIMENT; LIPID OXIDATION; LIPOPROTEIN BLOOD LEVEL; MALE; NORMAL HUMAN; WINE;

EID: 0031819525     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/68.2.258     Document Type: Article

References (38)

1. Kozararevic D, McGee D, Vojvodic N, Racic Z, Dawber T, Gordon T. Frequency of alcohol consumption and morbidity and mortality. Lancet 1980;1:613-6.
2. Marmot MG, Rose G, Shipley MJ, Thomas BJ. Alcohol and mortality: a U-shaped curve. Lancet 1981;1:580-3.
3. Shaper AG, Wannamethee G, Walker M. Alcohol and mortality in British men: explaining the U-shaped curve. Lancet 1988;1:1267-73.
4. Boffetta P, Garfinkel L. Alcohol drinking and mortality among men enrolled in an American Cancer Society prospective study. Epidemiology 1990;1:337-9.
5. Gaziano YM, Buring JE, Breslow JL, et al. Moderate alcohol intake increased levels of high density lipoprotein and its subfractions and decreased risk of myocardial infarction. N Engl J Med 1993;329:1829-33.
6. Renaud S, de Lorgeril M. Wine alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992;339:1523-6.
7. Klatsky AL, Armstrong MA, Freedman GD. Relation of alcoholic beverage use to subsequent coronary heart disease hospitalization. Am J Cardiol 1986;58:710-4.
8. Klatsky AL, Armstrong MA. Alcoholic beverage choice and risk of coronary heart disease mortality: do red wine drinkers fare best? Am J Cardiol 1993;71:467-9.
9. Gronback M, Deis A, Sørensen TJA, Becker U, Schnohr P, Jensen G. Mortality associated with moderate intakes of wine, beer, or spirits. Br Med J 1995;310:1165-9.
10. Frankel EN, Waterhouse AL, Teissedre PL. Principal phenolic phytochemicals in selected California wines and their antioxidant activity in inhibiting oxidation of human low-density lipoproteins. J Agric Food Chem 1995;43:890-4.
11. Witztum JL. The oxidation hypothesis of atherosclerosis. Lancet 1994;344:793-8.
12. Fuhrman B, Lavy A, Aviram M. Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation. Am J Clin Nutr 1995;61:549-54.
13. de Rijke YB, Demacker PNM, Assen NA, Sloots LM, Katan MB, Stalenhoef AFH. Red wine consumption does not affect oxidizability of low-density lipoproteins in volunteers. Am J Clin Nutr 1996;63:329-34.
14. Singleton SL, Rossi JA. Colorimetry of total phenols with phosphomolybdic phosphotungstic acid reagents. Am J Enol Viticulture 1965;16:144-58.
15. Price SF, Breen PJ, Valladao M, Watson BT. Cluster sun exposure and quercetin in Pinot noir grapes and wine. Am J Enol Viticulture 1995;46:187-94.
16. Gorog P, Semeria FJ, Gorog DA. Activation of the phagocytic system increases initial proliferation in hypercholesterolaemic rabbits. Atherosclerosis 1993;111:47-53.
17. Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and the application to monitoring the antioxidant status in premature neonates. Clin Sci 1993;84:407-12.
18. Leonhardt W, Hanefeld M, Müller G, et al. Impact of concentrations of glycated hemoglobin, α-tocopherol, copper and manganese on oxidation of low-density lipoproteins in patients with type I diabetes, type II diabetes and control subjects. Clin Chim Acta 1996;254:173-86.
19. Kleinveld HA, Hak-Lemmers LM, Stalenhoef AF, Demacker PN. Improved measurement of LDL susceptibility to copper-induced oxidation. Application of a short procedure for isolating LDL. Clin Chem 1992;38:2066-72.
20. McDowell IFW, McEneny J, Trimble ER. A rapid method for measurement of the susceptibility to oxidation of low-density lipoprotein. Ann Clin Biochem 1995;32:167-74.
21. Esterbauer H, Striegl G, Puhl H, Rotheneder M. Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic Res Commun 1989;6:67-75.
22. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978;52:302-10.
23. El-Saadani M, Esterbauer M, El-Sayed M, Goher M, Massar AY, Jurgens G. A spectrophotometric assay of lipid peroxides in serum lipoproteins using a commercially available reagent. J Lipid Res 1989;30:627-30.
24. Bradford MM. Analysis of protein. Anal Biochem 1976;72:248-54.
25. Fernandez-Checa JC, Garcia-Ruiz C, Ookkens M, Kapiowitz N. Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol fed rats. J Clin Invest 1991;87:397-405.
26. Lamb DJ, Leake DS. The effect of EDTA on the oxidation of low density lipoprotein. Atherosclerosis 1992;94:35-42.
27. Esterbauer H, Jurgens G, Quenenberger O, Koller E. Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes. J Lipid Res 1987;28:495-509.
28. Scheck LM, Wiseman SA, Tyburg LBM, van Tol A. Dialysis of isolated low density lipoprotein induces a loss of lipophilic antioxidants and increases the susceptibility to oxidation in vitro. Atherosclerosis 1995;117:139-44.
29. Afansiev IB, Dorozhko AI, Brodskii AV, Kostyuk AV, Potapovitch AL. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem Pharmacol 1989;38:1763-9.
30. Halliwell B, Gutteridge JMC. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1-85.
31. Morel I, Lescoat G, Cogrel P, et al. Antioxidant and iron chelating activities of the flavonoids catechins, quercetin and diosmetin on iron loaded rat hepatocyte cultures. Biochem Pharmacol 1993;45:13-9.
32. Simons LA, Von Konigsmark M, Balasubramanian S. What dose of vitamin E is required to reduce susceptibility of LDL to oxidation. Aust N Z J Med 1996;26:496-503.
33. Hartung GH, Foreyt JL, Reers RS, et al. Effect of alcohol dose on plasma lipoprotein subtractions and lipolytic enzyme activity in active and inactive men. Metabolism 1990;39:81-6.
34. St Leger AS, Moore F, Cochrane AL. Factors associated with cardiomortality in developed countries with particular reference to consumption of wine. Lancet 1979;1:1017-20.
35. Hennekens CH, Willett W, Rosner B, Cole DS, Mayrent SL. Effects of beer, wine, and liquor in coronary deaths. JAMA 1979;242:1973-4.
36. Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 1993;342:1007-11.
37. Hertog MGL, Kromhout D, Aravanis C, et al. Flavonoid intake and long-term risk of coronary heart disease and cancer in the Seven Countries Study. Arch Intern Med 1995;155:381-6.
38. Klurfield DM, Kritchevsky D. Differential effects of alcoholic beverages on experimental atherosclerosis in rabbits. Exp Mol Pathol 1981;34:62-71.