β-amyloid peptide expression is sufficient for myotube death: Implications for human inclusion body myopathy

Molecular and Cellular Neuroscience

Volumn 17, Issue 5, 2001, Pages 793-810

  Querfurth, Henry W ^a,b   Suhara, Toshimitsu ^a,b   Rosen, Kenneth M ^a,b   McPhie, Donna L ^c   Fujio, Yasushi ^a,b   Tejada, George ^d   Neve, Rachael L ^c   Adelman, Lester S ^d   Walsh, Kenneth ^a,b  

^a ST ELIZABETH'S MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MCLEAN HOSPITAL   (United States)

^d TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; DNA FRAGMENT; MEMBRANE PHOSPHOLIPID;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; GENE TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; INCLUSION BODY MYOSITIS; MOUSE; MUSCULAR DYSTROPHY; MYOTUBE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKELETAL MUSCLE;

ANIMALIA; HUMAN HERPESVIRUS 1;

EID: 0034991310     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2001.0972     Document Type: Article

References (72)

1. Myogenin expression, cell cycle withdrawal and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis
2. β-amyloid precursor epitopes in muscle fibers of inclusion body myositis
3. Use of anti-neurofilament antibody to identify paired-helical filaments in inclusion-body myositis
4. Sporadic inclusion-body myositis and hereditary inclusion-body myopathies
5. New advances in the understanding of sporadic inclusion-body myositis and hereditary inclusion-body myopathies
6. Light and electron microscopic localization of β-amyloid protein in muscle biopsies of patients with inclusion-body myositis
7. Twisted tubulofilaments of inclusion-body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau
8. Inclusion body myositis: Explanation for poor response to immunosuppressive therapy
9. Synergistic effect of β-amyloid protein and interferon gamma on nitric oxide production by C2C12 muscle cells
10. Cytotoxic mechanisms in inflammatory myopathies
11. Impairment in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein
12. Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats
13. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer's disease mutant does not enhance apoptosis
14. Alzheimer's Aβ(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
15. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease
16. Generation of bA4 from the amyloid precursor and fragments thereof
17. Inclusion body myositis: Pathologic changes
18. Apoptosis mediated neurotoxicity, induced by chronic application of β amyloid fragment 25-35
19. Amyloid-beta deposition in skeletal muscle of transgenic mice. Possible model of inclusion body myopathy
20. Upregulation of Fas/Fas ligand in inclusion body myositis
21. βPP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease
22. G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP
23. Filamentous nerve cell inclusions in neurodegenerative diseases
24. Inclusion body myositis and myopathies
25. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid β-peptide: Involvement of calcium and oxyradicals
26. LacZ gene transfer to skeletal muscle using a replication defective herpes simplex virus type 1 mutant vector
27. Herpes simplex virus type 1 vector mediated gene transfer to muscle
28. Inclusion body myositis: Abnormal protein accumulation does not trigger apoptosis
29. Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo
30. Transgenic mice over-expressing the C-99 fragment of βPP with an α-secretase site mutation develop a myopathy similar to human inclusion body myositis
31. Neurotoxicity of a carboxyl-terminal fragment of the Alzheimer's amyloid precursor protein
32. The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
33. Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Aβ stabilization
34. Beta-amyloid induces apoptosis in human-derived neurotypic ShSY5Y cells
35. A novel substrate for analyzing Alzheimer's disease gamma-secretase
36. Generation of high-titer defective HSV-1 vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells
37. Apoptosis is induced by β-amyloid in cultured central nervous system neurons
38. Inclusion body myositis
39. Formation of amyloid-like fibrils in COS cells overexpressing part of the Alzheimer amyloid precursor
40. Neuronal expression of β-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid β and cytoplasmic domains
41. Caspace-12 mediates endoplasmic-reticulum specific apoptosis and cytotoxicity by amyloid-β
42. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
43. Alzheimer's disease: A reexamination of the amyloid hypothesis
44. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer
45. Bcl-2 and Bax protein expression in human myopathies
46. Apoptosis in the failing heart
47. Age-dependent neuronal and synaptic degeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein
48. A suicide note from Alzheimer disease neurons?
49. Sporadic inclusion body myositis: Counts of different types of abnormal fibers
50. Beta-amyloid precursor protein mRNA is increased in inclusion-body myositis muscle
51. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with formation of intranuclear inclusions
52. Aberrant expression of bcl-2 gene family in Down's syndrome brains
53. MHC class I-mediated cytotoxicity does not induce apoptosis in muscle fibers nor in inflammatory T cells: Studies in patients with polymyositis, dermatomyositis, and inclusion body myositis
54. Inhibition of PC12 cell REDOX activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death
55. Evidence for apoptotic cell death in Alzheimer's disease
56. Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the β-amyloid precursor protein
57. Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis
58. Bax protein expression is increased in Alzheimer's brain: Correlations with DNA damage, Bcl-2 expression, and brain pathology
59. DNA-fragmentation and apoptosis-related proteins of muscle cells in motor neuron disorders
60. Apoptosis precedes necrosis of dystrophin deficient muscle
61. Endonuclease activities associated with high molecular weight and internucleosomal DNA fragmentation in apoptosis
62. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation
63. Caspace cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
64. Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42
65. Intracellular APP processing and Aβ production in Alzheimer's disease
66. Identification and characterization of C-terminal fragments of the b-amyloid precursor produced in cell culture
67. G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP
68. An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease
69. Nitric oxide-induced oxidative stress in autosomal recessive and dominant inclusion-body myopathies
70. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
71. Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells
72. Signal sequences: The same yet different