Neuronal expression of β-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid β and cytoplasmic domains

Journal of Biological Chemistry

Volumn 272, Issue 40, 1997, Pages 24743-24746

  McPhie, Donna L ^a   Lee, Robert K K ^b   Eckman, Christopher B ^c   Olstein, Daniel H ^a   Durham, Stephanie P ^a   Yager, Debra ^c   Younkin, Steven G ^c   Wurtman, Richard J ^b   Neve, Rachael L ^a  

^a MCLEAN HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; INTRACELLULAR TRANSPORT; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SYNAPTOSOME;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CYTOPLASM; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEURONS; PEPTIDE FRAGMENTS; POINT MUTATION; RATS; RECOMBINANT PROTEINS; SIMPLEXVIRUS; TRANSFECTION;

ANIMALIA; HERPES; SIMPLEXVIRUS;

EID: 0030867815     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.40.24743     Document Type: Article

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