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Volumn 18, Issue 8, 2000, Pages 835-841

Emerging themes in medicinal glycoscience

Author keywords

Antibiotic; Glycoconjugate; Synthesis; Therapeutic; Vaccine

Indexed keywords

ANTIBIOTIC AGENT; CARBOHYDRATE; GLYCOCONJUGATE; VACCINE;

EID: 0033897809     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/78435     Document Type: Review
Times cited : (151)

References (103)
  • 1
    • 0027318961 scopus 로고
    • Biological roles of oligosaccharides: All of the theories are correct
    • (1993) Glycobiology , vol.3 , pp. 97-130
    • Varki, A.1
  • 2
    • 0001094662 scopus 로고    scopus 로고
    • Glycobiology: Toward understanding the function of sugars
    • (1996) Chem. Rev. , vol.96 , pp. 683-720
    • Dwek, R.A.1
  • 6
    • 0029858031 scopus 로고    scopus 로고
    • Selectins and their ligands: Current concepts and controversies
    • (1996) Blood , vol.88 , pp. 3259-3287
    • Kansas, G.S.1
  • 9
    • 4244211997 scopus 로고    scopus 로고
    • Heparinoid mimetics
    • Topics in current chemistry. Glycoscience: Synthesis of substrate analogs and mimetics (eds Driguez, H. and Thiem, J.) (Springer-Verlag, Berlin; 1997)
    • Wessel, H.P.1
  • 11
    • 0002013251 scopus 로고    scopus 로고
    • Cell surface carbohydrates: Cell-type specific expression
    • Molecular glycobiology (eds Fukuda, M. and Hindsgaul, O.) (IRL Press, Oxford, UK; 1994)
    • Fukuda, M.1
  • 15
    • 0022462129 scopus 로고
    • Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides
    • (1986) Biochem. Cell Biol. , vol.64 , pp. 163-181
    • Schachter, H.1
  • 21
    • 0031452608 scopus 로고    scopus 로고
    • Comparative lipase-catalyzed hydrolysis of ethylene glycol derived esters. The 2-methoxyethyl ester as a protective group in peptide and glycopeptide synthesis
    • (1997) Synthesis , pp. 1499-1511
    • Gewehr, M.1    Kunz, H.2
  • 25
    • 0033596308 scopus 로고    scopus 로고
    • Fmoc-based synthesis of peptide (α)thioesters: Application to the total chemical synthesis of a glycoprotein by native chemical ligation
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 11684-11689
    • Shin, Y.1
  • 27
    • 0030670057 scopus 로고    scopus 로고
    • Combined chemical and enzymatic synthesis of a C-glycopeptide and its inhibitory activity toward glycoamidases
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 11137-11146
    • Wang, L.-X.1
  • 33
    • 0027287506 scopus 로고
    • Rational design of potent sialidase-based inhibitors of influenza virus replication
    • (1993) Nature , vol.363 , pp. 418-423
    • Von Itzstein, M.1
  • 34
    • 0031048319 scopus 로고    scopus 로고
    • Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 681-690
    • Kim, C.U.1
  • 35
    • 0026324207 scopus 로고
    • Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide
    • (1991) Science , vol.253 , pp. 320-323
    • Harouse, J.M.1
  • 36
    • 0030947785 scopus 로고    scopus 로고
    • Synthetic soluble analogs of galactosylceramide (GalCer) bind to the V3 domain of HIV-1 gp120 and inhibit HIV-1-induced fusion and entry
    • (1997) J. Biol. Chem. , vol.272 , pp. 7245-7252
    • Fantini, J.1
  • 38
    • 0027370433 scopus 로고
    • Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production
    • (1993) Cell , vol.74 , pp. 969-978
    • Zapp, M.L.1    Stern, S.2    Green, M.R.3
  • 39
    • 0029905917 scopus 로고    scopus 로고
    • Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA Rev responsive element
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 10150-10155
    • Park, W.K.C.1    Auer, M.2    Jaksche, H.3    Wong, C.-H.4
  • 43
    • 0031576683 scopus 로고    scopus 로고
    • The roles of dimerization and membrane anchoring in activity of glycopeptide antibiotics against vancomycin-resistant bacteria
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 12041-12047
    • Sharman, G.J.1
  • 49
    • 0026355435 scopus 로고
    • Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: Biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA
    • (1990) Biochemistry , vol.30 , pp. 10408-10415
    • Bugg, T.D.H.1
  • 51
    • 0033574743 scopus 로고    scopus 로고
    • Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala
    • (1999) Science , vol.284 , pp. 507-511
    • Ge, M.1
  • 55
    • 0028941067 scopus 로고
    • E5531, a pure endotoxin antagonist of high potency
    • (1995) Science , vol.268 , pp. 80-83
    • Christ, W.J.1
  • 56
    • 0023279472 scopus 로고
    • A new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis
    • (1987) Nature , vol.327 , pp. 730-732
    • Hammond, S.M.1
  • 57
    • 0034646694 scopus 로고    scopus 로고
    • Antibacterial agents that target Lipid A biosynthesis in gram-negative bacteria
    • (2000) J. Biol. Chem. , vol.275 , pp. 11002-11009
    • Jackman, J.E.1
  • 61
    • 0034628502 scopus 로고    scopus 로고
    • Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
    • (2000) Nature , vol.403 , pp. 669-672
    • Kitov, P.I.1
  • 63
    • 0030729928 scopus 로고    scopus 로고
    • Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues
    • (1997) EMBO J. , vol.16 , pp. 6667-6675
    • Smith, T.K.1
  • 67
    • 0033591922 scopus 로고    scopus 로고
    • Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 6527-6541
    • Greenberg, W.A.1
  • 68
    • 0034738144 scopus 로고    scopus 로고
    • Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 5230-5231
    • Sucheck, S.J.1
  • 72
    • 0033567991 scopus 로고    scopus 로고
    • Enhanced inhibition of human anti-gal antibody binding to mammalian cells by synthetic α-gal epitope polymers
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 8174-8181
    • Wang, J.-Q.1
  • 75
    • 0033612332 scopus 로고    scopus 로고
    • Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen
    • (1999) Science , vol.284 , pp. 1523-1527
    • McKenney, D.1
  • 76
    • 0030826451 scopus 로고    scopus 로고
    • Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells
    • (1997) Science , vol.278 , pp. 283-286
    • Moody, D.B.1
  • 78
    • 0028036584 scopus 로고
    • Polysialic acid engineering: Synthesis of polysialylated neoglycosphingolipids by using the polysialytransferase from neuroinvasive Escherichia coli K1
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11427-11431
    • Cho, J.-W.1    Troy, F.A.2
  • 80
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of V(α)14 NKT cells by glycosylceramides
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 82
    • 0033558181 scopus 로고    scopus 로고
    • A fully synthetic Globo H carbohydrate vaccine induces a focused humoral response in prostate cancer patients: A proof of principle
    • (1999) Angew. Chem. Int. Ed. Engl. , vol.38 , pp. 563-566
    • Ragupathi, G.1
  • 83
    • 0032943932 scopus 로고    scopus 로고
    • Evidence of a cellular immune response against sialyl-T(n) in breast and ovarian cancer patients after high-dose chemotherapy, stem cell rescue, and immunization with theratope ST(n)-KLH cancer vaccine
    • (1999) J. Immunother. , vol.22 , pp. 54-66
    • Sandmaier, B.M.1
  • 85
    • 0030935175 scopus 로고    scopus 로고
    • The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes
    • (1997) Int. J. Cancer , vol.70 , pp. 699-705
    • Wang, S.-Y.1
  • 86
    • 0030937840 scopus 로고    scopus 로고
    • Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin
    • (1997) Science , vol.276 , pp. 428-431
    • Platt, F.M.1
  • 93
    • 0027770951 scopus 로고
    • Therapeutic effect of intradermal injections with difucosyl lactosamine (dimeric Le(x)) on patients with rheumatoid arthritis
    • (1993) J. Rheumatol. , vol.20 , pp. 2038-2045
    • Ochi, T.1
  • 94
    • 0033597941 scopus 로고    scopus 로고
    • Neuronal protection in stroke by an sLe(x)-glycosylated complement inhibitory protein
    • (1999) Science , vol.285 , pp. 595-599
    • Huang, J.1
  • 96
    • 0344938369 scopus 로고    scopus 로고
    • Synthesis of thrombin-inhibiting heparin mimetics without side effects
    • (1999) Nature , vol.398 , pp. 417-422
    • Petitou, M.1
  • 98
    • 0026848764 scopus 로고
    • Glycoprotein pharmaceuticals: Scientific and regulatory considerations, and the US orphan drug act
    • (1992) Trends Biotechnol. , vol.10 , pp. 114-120
    • Liu, D.T.-Y.1
  • 100
    • 9444236174 scopus 로고    scopus 로고
    • Small peptides as potent mimetics of the protein hormone erythropoietin
    • (1996) Science , vol.273 , pp. 458-463
    • Wrighton, N.C.1
  • 101
    • 0029798402 scopus 로고    scopus 로고
    • Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 Å
    • (1996) Science , vol.273 , pp. 464-471
    • Livnah, O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.