Glycosphingolipid antigens and cancer therapy

Chemistry and Biology

Volumn 4, Issue 2, 1997, Pages 97-104

  Hakomori, Sen Itiroh ^a   Zhang, Yongmin ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0031080051     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(97)90253-2     Document Type: Review

References (47)

1. Hakomori, S. & Murakami, W.T. (1968). Glycolipids of hamster fibroblasts and derived malignant-transformed cell lines. Proc. Natl Acad. Sci. USA 59, 254-261.
2. Mora, P.T., Brady, R.O., Bradley, R.M. & McFarland, V.W. (1969). Gangliosides in DNA virus-transformed and spontaneously transformed tumorigenic mouse cell lines. Proc. Natl Acad. Sci. USA 63, 1290-1296.
3. Rosenfelder, G., Young, W.W.J. & Hakomori, S. (1977). Association of the glycolipid pattern with antigenic alterations in mouse fibroblasts transformed by murine sarcoma virus. Cancer Res. 37, 1333-1339.
4. Nicolaou, K.C., Caulfield, T., Kataoka, H. & Kumazawa, T. (1988). A practical and enantioselective synthesis of glycosphingolipids and related compounds: total synthesis of globotriaosylceramide (Gb3). J. Am. Chem. Soc. 110, 7910-7912.
5. Bilodeau, M.T., et al., & Zhang, S. (1995). Total synthesis of a human breast tumor associated antigen. J. Am. Chem. Soc. 117, 7840-7841.
6. Lassaletta, J.M., Carlsson, K., Garegg, P.J. & Schmidt, R.R. (1996). Total synthesis of sialylgalactosylgloboside: stage-specific embryonic antigen 4. J. Org. Chem. 61, 6873-6880.
7. Sugimoto, M. & Ogawa, T. (1985). Synthesis of a hematoside (GM3-ganglioside) and a stereoisomer, Glycoconj. J. 2, 5-9.
8. Ito, Y., Numata, M., Sugimoto, M, & Ogawa, T. (1989). Highly stereoselective synthesis of ganglioside GD3. J. Am. Chem. Soc. 111, 8508-8610.
9. Ishida, H., et al., & Hasegawa, A. (1994). A facile total synthesis of ganglioside GD2. Carbohydr. Res. 252, 283-290.
10. 4Cer. Carbohydr. Res. 167, 197-210.
11. βCer: pivaloyl auxiliary for stereocontrolled glycosylation. Tetrahedron Lett. 29, 5267-5270.
12. Kameyama, A., Ishida, H., Kiso, M. & Hasegawa, A. (1991). Synthetic studies on sialoglycoconjugates 22: total synthesis of tumor-associated ganglioside, stalyl Lewis X, J. Carbohydr. Chem. 10, 549-560.
13. x sequence. Glycoconj. J. 13, 203-211.
14. Nores, G.A., Dohi, T., Taniguchi, M. & Hakomori, S. (1987). Density-dependent recognition of cell surface GM3 by a certain antimelanoma antibody, and GM3 lactone as a possible immunogen: requirements for tumor-associated antigen and immunogen. J. Immunol. 139, 3171-3176.
15. Ito, M., Suzuki, E., Naiki, M., Sendo, F. & Arai, S. (1984). Carbohydrates as tumor-associated antigens. Int. J. Cancer 34, 689-697.
16. Kannagi, R., Nudelman, E.D., Levery, S.B. & Hakomori, S. (1982). A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen, SSEA-1. J. Biol. Chem. 257, 14865-14874.
17. Lloyd, K.O., Gordon, C.M., Thampoe, I.J. & DiBenedetto, C. (1992). Cell surface accessibility of individual gangliosides in malignant melanoma cells to antibodies is influenced by the total ganglioside composition. Cancer Res. 52, 4948-4953.
18. Hakomori, S. (1996). Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res. 56, 5309-5318.
19. Kojima, N., Shiota, M., Sadahira, Y., Handa, K. & Hakomori, S. (1992). Cell adhesion in a dynamic Slow system as compared to static system. J. Biol. Chem. 267, 17264-17270.
20. Otsuji, E., Park, Y.S., Tashiro, K., Kojima, N., Toyokuni, T. & Hakomori, S. (1995). Inhibition of B16 melanoma metastasis by administration of GM3- or GgS-liposomes: blocking adhesion of melanoma cells to endothelial cells (anti-adhesion therapy) via inhibition of GM3-Gg3Cer or GM3-LacCer interaction. Int. J. Oncol. 6, 319-327.
21. Saito, S., Levery, S.B., Salyan, M.E.K., Goldberg, R.I., & Hakomori, S. (1994). Common tetrasaccharide epitope NeuAcα2→3Galβ1→ 3(NeuAcα2→6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities. J. Biol. Chem. 269, 5644-5652.
22. Satoh, M., et al., & Hakomori, S. (1996). Disialosyl galactosylgloboside as an adhesion molecule expressed on renal cell carcinoma and its relationship to metastatic potential. Cancer Res. 56, 1932-1938.
23. 6). J. Biol. Chem. 259, 10511-10517.
24. Magnani, J.L., Steplewski, Z., Koprowski, H. & Ginsburg, V. (1983). Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as mucin. Cancer Res. 43, 5489-5492.
25. x. Science 250, 1130-1132.
26. x is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. J. Biol. Chem. 266, 14869-14872.
27. Takada, A., et al., & Kannagi, R. (1991). Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A. Biochem. Biophys. Res. Commun. 179, 713-719.
28. x, and sulfated glycans modulate this binding. Biochem. Biophys. Res. Commun. 181, 1223-1230.
29. Takada, A., et al., & Kannagi, R. (1993). Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res. 53, 354-361.
30. a. Int. J. Oncol. 6, 773-781.
31. Stroud, M.R., Handa, K., Salyan, M.E.K., Ito, K., Levery, S.B. & Hakomori, S. (1996). Monosialogangliosides of human myelogenous leukemia HL60 cells and normal human leukocytes. 2. Characterization of E-selectin binding fractions, and structural requirements for physiological binding to E-selectin. Biochemistry 35, 770-778.
32. x in static vs. dynamic flow systems. J. Biol. Chem., in press.
33. Hakomori, S. (1906). Sphingolipid-dependent protein kinases. In Intracellular signal transduction (Adv. Pharmacol. 36). Academic Press, San Diego, USA. pp 155-171.
34. Hannun, Y.A. & Linardic, C.M. (1993). Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids, Biochim. Biophys. Acta 1154, 223-236.
35. Spiegel, S., Foster, D. & Kolesnick, R.N. (1996). Signal transduction through lipid second messengers. Curr. Opin. Cell Biol. 8, 159-167.
36. Kojima, N. & Hakomori, S. (1991). Synergistic effect of two cell recognition systems: glycosphingolipid-glycosphingolipid interaction and integrin receptor interaction with pericellular matrix protein. Glycobiology 1, 623-630.
37. Lloyd, K.O. (1993). Tumor antigens known to be immunogenic in man. Ann. N.Y. Acad. Sci. 690, 50-58.
38. Livingston, P.O. (1995). Approaches to augmenting the immunogenicity of melanoma gangliosides: from whole melanoma cells to ganglioside-KLH conjugate vaccines. Immunol. Rev. 145, 147-166.
39. Becker, J.C., Varki, N., Gillies, S.D., Furukawa, K. & Reisfeld, R.A. (1996). An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response. Proc. Natl Acad. Sci. USA 93, 7826-7831.
40. Radin, N.S. & Inokuchi, J. (1988). Glucosphingolipids as sites of action in the chemotherapy of cancer. Biochem. Pharmacol. 37, 2879-2886.
41. Sadahira, Y., Ruan, F., Hakomori, S. & Igarashi, Y. (1992). Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. Proc. Natl Acad, Sci. USA 89, 9686-9690.
42. Park, Y. S., Ruan, F., Hakomori, S. & Igarashi, Y. (1995). Cooperative inhibitory effect of N,N,N-trimethylsphingosine and sphingosine-1-phosphate, co-incorporated in liposomes, on B16 melanoma cell metastasis: cell membrane signaling as a target in cancer therapy IV. Int. J. Oncol. 7, 487-494.
43. Hakomori, S. (1989). Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res. 52, 257-331.
44. Farkas-Hirnsley, H., Hill, R., Rosen, B., Arab, S. & Lingwood, C.A. (1995). The bacterial colicin active against tumor cells in vitro and in vivo is verotoxin 1. Proc. Natl, Acad. Sci. USA 92, 6996-7000.
45. Satch, M., et al., & Hakomori, S. (1996). Disialosyl galactosylgloboside as an adhesion molecules expressed on renal cell carcinoma and its relationship to metastatic potential. Cancer Res. 56, 1932-1938.
46. IUPAC-IUB Commission on Biochemical Nomenclature (CBN) (1977). The Nomenclature of Lipids, Recommendations 1976. Lipids 12, 455-463.
47. 6) as human tumor-associated antigen. J. Biol. Chem. 266, 8439-8446.