-
1
-
-
0007908456
-
-
Lectures on Pathological Anatomy, 2nd ed.. London: Churchill
-
(1875)
-
-
Wilks, S.1
Moxon, W.2
-
7
-
-
0032435314
-
Experimental models to study molecular mechanisms underlying intestinal inflammation
-
(1998)
Ann. NY Acad. Sci.
, vol.859
, pp. 85-95
-
-
Elson, C.O.1
Cong, Y.2
Brandwein, S.3
Weaver, C.T.4
McCabe, R.P.5
Mahler, M.6
Sundberg, J.P.7
Leiter, E.H.8
-
11
-
-
0027422089
-
Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice
-
(1993)
Cell
, vol.75
, pp. 203-205
-
-
Strober, W.1
Ehrhardt, R.O.2
-
16
-
-
0008700094
-
Inflammatory bowel disease workshop. Vail, Colorado, March 22 and 23, 1998. Maintenance therapy in IBD
-
discussion 295-301
-
(1998)
Inflamm. Bowel Dis.
, vol.4
, pp. 292-295
-
-
Tremaine, W.J.1
-
25
-
-
0031811879
-
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain
-
(1998)
Gut
, vol.43
, pp. 71-78
-
-
Matsumoto, S.1
Okabe, Y.2
Setoyama, H.3
Takayama, K.4
Ohtsuka, J.5
Funahashi, H.6
Imaoka, A.7
Okada, Y.8
Umesaki, Y.9
-
30
-
-
0029061801
-
Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice
-
(1995)
Nat. Genet.
, vol.10
, pp. 143-150
-
-
Rudolph, U.1
Finegold, M.J.2
Rich, S.S.3
Harriman, G.R.4
Srinivasan, Y.5
Brabet, P.6
Boulay, G.7
Bradley, A.8
Birnbaumer, L.9
-
36
-
-
0029102210
-
Severe colitis in mice with aberrant thymic selection
-
(1995)
Immunity
, vol.3
, pp. 27-38
-
-
Hollander, G.A.1
Simpson, S.J.2
Mizoguchi, E.3
Nichogiannopoulou, A.4
She, J.5
Gutierrez-Ramos, J.-C.6
Bhan, A.K.7
Burakoff, S.J.8
Wang, B.9
Terhorst, C.10
-
38
-
-
0033559891
-
+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype
-
(1999)
J. Immunol.
, vol.162
, pp. 3702-3710
-
-
Claesson, M.H.1
Bregenholt, S.2
Bonhagen, K.3
Thoma, S.4
Moller, P.5
Grusby, M.J.6
Leithauser, F.7
Nissen, M.H.8
Reimann, J.9
-
40
-
-
0032472838
-
Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa
-
(1998)
J. Exp. Med.
, vol.187
, pp. 389-402
-
-
Watanabe, M.1
Ueno, Y.2
Yajima, T.3
Okamoto, S.4
Hayashi, T.5
Yamazaki, M.6
Iwao, Y.7
Ishii, H.8
Habu, S.9
Uehira, M.10
Nishimoto, H.11
Ishikawa, H.12
Hata, J.13
Hibi, T.14
-
41
-
-
0032550312
-
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1225-1234
-
-
Simpson, S.J.1
Shah, S.2
Comiskey, M.3
De Jong, Y.P.4
Wang, B.5
Mizoguchi, E.6
Bhan, A.K.7
Terhorst, C.8
-
45
-
-
0029023008
-
Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes
-
(1995)
Biochem. J.
, vol.311
, pp. 293-297
-
-
Tomita, M.1
Itoh, H.2
Ishikawa, N.3
Higa, A.4
Ide, H.5
Murakumo, Y.6
Maruyama, H.7
Koga, Y.8
Nawa, Y.9
-
48
-
-
0030752587
-
Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis
-
(1997)
Gastroenterology
, vol.113
, pp. 825-832
-
-
Egger, B.1
Procaccino, F.2
Lakshmanan, J.3
Reinshagen, M.4
Hoffmann, P.5
Patel, A.6
Reuben, W.7
Gnanakkan, S.8
Liu, L.9
Barajas, L.10
Eysselein, V.E.11
-
49
-
-
0027054057
-
Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 2409-2421
-
-
Romano, M.1
Polk, W.H.2
Awad, J.A.3
Arteaga, C.L.4
Nanney, L.B.5
Wargovich, M.J.6
Kraus, E.R.7
Boland, C.R.8
Coffey, R.J.9
-
52
-
-
0030018186
-
+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice
-
(1996)
J. Exp. Med.
, vol.184
, pp. 241-251
-
-
Davidson, N.J.1
Leach, M.W.2
Fort, M.M.3
Snipes, L.T.4
Kuhn, R.5
Muller, W.6
Berg, D.J.7
Rennick, D.M.8
-
54
-
-
0029085294
-
T cells in inflammatory bowel disease: Protective and pathogenic roles
-
(1995)
Immunity
, vol.3
, pp. 171-174
-
-
Powrie, F.1
-
59
-
-
0030818051
-
Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1743-1750
-
-
Neurath, M.F.1
Fuss, I.2
Pasparakis, M.3
Alexopoulou, L.4
Haralambous, S.5
Meyer zum Buschenfelde, K.6
Strober, W.7
Kollias, G.8
-
66
-
-
0032530697
-
IL-12, but not IFN-gamma, plays a major role in sustaining the Chronic phase of colitis in IL-10-deficient mice
-
(1998)
J. Immunol.
, vol.161
, pp. 3143-3149
-
-
Davidson, N.J.1
Hudak, S.A.2
Lesley, R.E.3
Menon, S.4
Leach, M.W.5
Rennick, D.M.6
-
68
-
-
0031568526
-
IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
-
(1997)
J. Immunol.
, vol.158
, pp. 1541-1550
-
-
Kohno, K.1
Kataoka, J.2
Ohtsuki, T.3
Suemoto, Y.4
Okamoto, I.5
Usui, M.6
Ikeda, M.7
Kurimoto, M.8
-
70
-
-
0033152023
-
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
-
(1999)
J. Immunol.
, vol.162
, pp. 6829-6835
-
-
Pizarro, T.T.1
Michie, M.H.2
Bentz, M.3
Woraratanadharm, J.4
Smith M.F., Jr.5
Foley, E.6
Moskaluk, C.A.7
Bickston, S.J.8
Cominelli, F.9
-
71
-
-
0033168120
-
Bioactive IL-18 expression is up-regulated in Crohn's disease
-
(1999)
J. Immunol.
, vol.163
, pp. 143-147
-
-
Monteleone, G.1
Trapasso, F.2
Parrello, T.3
Biancone, L.4
Stella, A.5
Iuliano, R.6
Luzza, F.7
Fusco, A.8
Pallone, F.9
-
73
-
-
18844481515
-
Defective NK cell activity and Th1 response in IL-18-deficient mice
-
(1998)
Immunity
, vol.8
, pp. 383-390
-
-
Takeda, K.1
Tsutsui, H.2
Yoshimoto, T.3
Adachi, O.4
Yoshida, N.5
Kishimoto, T.6
Okamura, H.7
Nakanishi, K.8
Akira, S.9
-
77
-
-
0030209985
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
(1996)
J. Immunol.
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
Klein, J.S.4
De la Motte, C.5
Strong, S.A.6
Fiocchi, C.7
Strober, W.8
-
83
-
-
0030239820
-
Hapten-induced model of murine inflammatory bowel disease: Mucosa immune responses and protection by tolerance
-
(1996)
J. Immunol.
, vol.157
, pp. 2174-2185
-
-
Elson, C.O.1
Beagley, K.W.2
Sharmanov, A.T.3
Fujihashi, K.4
Kiyono, H.5
Tennyson, G.S.6
Cong, Y.7
Black, C.A.8
Ridwan, B.W.9
McGhee, J.R.10
-
86
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
(1998)
Infect. Immun.
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.B.8
-
87
-
-
0027933817
-
Role of intestinal microflora in chronic inflammation and ulceration of the rat colon
-
(1994)
Gut
, vol.35
, pp. 1090-1097
-
-
Videla, S.1
Vilaseca, J.2
Guarner, F.3
Salas, A.4
Treserra, F.5
Crespo, E.6
Antolin, M.7
Malagelada, J.R.8
-
88
-
-
0033000343
-
IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Schultz, M.1
Tonkonogy, S.L.2
Sellon, R.K.3
Veltkamp, C.4
Godfrey, V.L.5
Kwon, J.6
Grenther, W.B.7
Balish, E.8
Horak, I.9
Sartor, R.B.10
-
89
-
-
0032425062
-
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
-
(1998)
Infect. Immun.
, vol.66
, pp. 5157-5166
-
-
Kullberg, M.C.1
Ward, J.M.2
Gorelick, P.L.3
Caspar, P.4
Hieny, S.5
Cheever, A.6
Jankovic, D.7
Sher, A.8
-
92
-
-
0031114247
-
+, CD45RB(high) T cells to SCID recipients
-
(1997)
J. Immunol.
, vol.158
, pp. 3464-3473
-
-
Aranda, R.1
Sydora, B.C.2
McAllister, P.L.3
Binder, S.W.4
Yang, H.Y.5
Targan, S.R.6
Kronenberg, M.7
-
93
-
-
0032520267
-
Generation of intestinal mucosal lymphocytes in SCID mice reconstituted with mature, thymus-derived T cells
-
(1998)
J. Immunol.
, vol.160
, pp. 2608-2618
-
-
Camerini, C.V.1
Sydora, B.C.2
Aranda, R.3
Nguyen, C.4
MacLean, C.5
McBride, W.H.6
Kronenberg, M.7
-
107
-
-
0031945841
-
Current concepts in mucosal immunity. III. Ontogeny and function of gamma delta T cells in the intestine
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Kagnoff, M.F.1
-
109
-
-
0030960069
-
Changes in human mucosal γδ T cell repertoire and function associated with the disease process in inflammatory bowel disease
-
(1997)
Mol. Med.
, vol.3
, pp. 183-203
-
-
McVay, L.D.1
Li, B.2
Biancaniello, R.3
Creighton, M.A.4
Bachwich, D.5
Lichtenstein, G.6
Rombeau, J.L.7
Carding, S.R.8
-
110
-
-
0028149834
-
Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease
-
(1994)
Clin. Exp. Immunol.
, vol.98
, pp. 83-88
-
-
Giacommelli, R.1
Parzanese, I.2
Frieri, G.3
Passacantando, A.4
Pizzuto, F.5
Pimpo, T.6
Cipriani, P.7
Viscido, A.8
Caprilli, R.9
Tonietti, G.10
-
112
-
-
0029016752
-
Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6147-6151
-
-
Komano, H.1
Fujiura, Y.2
Kawaguchi, M.3
Matsumoto, S.4
Hashimoto, Y.5
Obana, S.6
Mombaerts, P.7
Tonegawa, S.8
Yamamoto, H.9
Itohara, S.10
Nanno, M.11
Ishikawa, H.12
-
116
-
-
0030016911
-
Keratinocyte growth factor is highly overexpressed in inflammatory bowel disease
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 521-529
-
-
Brauchle, M.1
Madlener, M.2
Wagner, A.D.3
Angermeyer, K.4
Lauer, U.5
Hofschneider, P.H.6
Gregor, M.7
Werner, S.8
-
125
-
-
0031043778
-
Randomized controlled trial of CDP571 antibody to tumor necrosis factor-alpha in Crohn's disease
-
(1997)
Lancet
, vol.349
, pp. 521-524
-
-
Stack, W.A.1
Mann, S.D.2
Roy, A.J.3
Heath, P.4
Sopwith, M.5
Freeman, J.6
Holmes, J.7
Long, R.8
Forbes, A.9
Kamm, M.A.10
Hawkey, C.J.11
-
126
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
128
-
-
0032923705
-
Tumor necrosis factor alpha antibody (inflixymab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis
-
(1999)
Gastroenterology
, vol.116
, pp. 22-28
-
-
Baert, F.1
D'Haens, G.R.2
Peeters, M.3
Hiele, M.I.4
Schaible, T.F.5
Shealy, D.6
Geboes, D.7
Rutgeerts, P.J.8
-
129
-
-
0032913394
-
Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial
-
(1999)
Gastroenterology
, vol.116
, pp. 1029-1034
-
-
D'Haens, G.1
Van Deventer, S.2
Van Hogezand, R.3
Chalmers, D.4
Kothe, C.5
Baert, F.6
Braakman, T.7
Schaible, T.8
Geboes, K.9
Rutgeerts, P.10
-
130
-
-
0007912670
-
Neutralization of tumor necrosis factor by a soluble p75 receptor-Fc molecule (Enbrel(TM)) ameliorates chronic dextran sodium sulfate-induced colitis in mice
-
Experimental Models of Immune Dysregulation and Mucosal Inflammation: Impact on the Understanding and Treatment of the Inflammatory Bowel Diseases. Keystone Symposia. Santa Fe, NM
-
(1999)
, pp. 43
-
-
Gliniak, B.1
Schuh, J.C.L.2
Lee, T.3
-
131
-
-
0031904714
-
Computer-assisted rational design of immunosuppressive compounds
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 748-752
-
-
Grassy, G.1
Calad, B.2
Yasri, A.3
Lahana, R.4
Woo, J.5
Iyer, S.6
Kaczorek, M.7
Floc'H, R.8
Buelow, R.9
-
141
-
-
0030980684
-
An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 988-1000
-
-
Bennett, C.F.1
Kornbrust, D.2
Henry, S.3
Stecker, K.4
Howard, R.5
Cooper, S.6
Dutson, S.7
Hall, W.8
Jacoby, H.I.9
-
144
-
-
0031595210
-
Nuclear factor kappaB is activated in macrophages and epithelial ceils of inflamed intestinal mucosa
-
(1998)
Gastroenterology
, vol.115
, pp. 357-369
-
-
Rogler, G.1
Brand, K.2
Vogl, D.3
Page, S.4
Hofmeister, R.5
Andus, T.6
Knuechel, R.7
Baeuerle, P.A.8
Scholmerich, J.9
Gross, V.10
-
146
-
-
0028080029
-
Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1764-1777
-
-
Housley, R.M.1
Morris, C.F.2
Boyle, W.3
Ring, B.4
Biltz, R.5
Tarpley, J.E.6
Aukerman, S.L.7
Devine, P.L.8
Whitehead, R.H.9
Pierce, G.F.10
-
150
-
-
7344260161
-
Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis
-
(1998)
Gut
, vol.43
, pp. 64-70
-
-
Egger, B.1
Carey, H.V.2
Procaccino, F.3
Chai, N.N.4
Sandgren, E.P.5
Lakshmanan, J.6
Buslon, V.S.7
French, S.W.8
Buchler, M.W.9
Eysselein, V.E.10
-
151
-
-
0028306753
-
Protective effect of epidermal growth factor in an experimental model of colitis in rats
-
(1994)
Gastroenterology
, vol.107
, pp. 12-17
-
-
Procaccino, F.1
Reinshagen, M.2
Hoffmann, P.3
Zeeh, J.M.4
Lakshmanan, J.5
McRoberts, J.A.6
Patel, A.7
French, S.8
Eysselein, V.E.9
-
152
-
-
0031702821
-
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6063-6074
-
-
Hu, M.C.1
Qiu, W.R.2
Wang, Y.P.3
Hill, D.4
Ring, B.D.5
Scully, S.6
Bolon, B.7
DeRose, M.8
Luethy, R.9
Simonet, W.S.10
Arakawa, T.11
Danilenko, D.M.12
|