Computer-assisted rational design of immunosuppressive compounds

Nature Biotechnology

Volumn 16, Issue 8, 1998, Pages 748-752

  Grassy, Gérard ^a   Galas, Bernard ^b   Yasri, Abdelaziz ^c   Lahana, Roger ^c   Woo, Jacky ^d   Iyer, Suhasini ^d   Kaczorek, Michel ^c   Floc'h, Robert ^d   Buelow, Roland ^d  

^a CNRS   (France)

^b Centre National de la Recherche Scientifique   (France)

^c Synt:em   (France)

^d GENZYME CORPORATION   (United States)

Author keywords

Applied immunology; Virtual chemistry; Virtual screening

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOSUPPRESSIVE AGENT; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPUTER ASSISTED DIAGNOSIS; ENANTIOMER; GRAFT SURVIVAL; HEART TRANSPLANTATION; HLA SYSTEM; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VECTOR CONTROL;

ANIMALS; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; CONSENSUS SEQUENCE; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIGANDS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; PEPTIDE LIBRARY; PEPTIDES; PROTEIN CONFORMATION; T-LYMPHOCYTES, CYTOTOXIC; TRANSPLANTATION, HOMOLOGOUS;

ANIMALIA;

EID: 0031904714     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0898-748     Document Type: Article

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