Reduced susceptibility of mice overexpressing transforming growth factor α to dextran sodium sulphate induced colitis

Gut

Volumn 43, Issue 1, 1998, Pages 64-70

  Egger, B ^a   Carey, H V ^b   Procaccino, F ^a   Chai, N N ^a   Sandgren, E P ^b   Lakshmanan, J ^a   Buslon, V S ^a   French, S W ^a   Buchler M W ^c   Eysselein, V E ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Colitis; Dextran sodium sulphate; Epidermal growth factor; Inflammatory bowel disease; Transforming growth factor ; Transgenic mice

Indexed keywords

BROXURIDINE; DEXTRAN SULFATE; DRINKING WATER; MUCIN; TRANSFORMING GROWTH FACTOR ALPHA; ZINC SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE OVEREXPRESSION; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE REGENERATION; TRANSGENIC MOUSE;

EID: 7344260161     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.43.1.64     Document Type: Article

References (48)

1. Procaccino F, Reinshagen M, Hoffmann P, et al. Protective effect of epidermal growth factor in an experimental model of colitis in rats. Gastroenterology 1994;107:12-17.
2. Luck MS, Bass P. Effect of epidermal growth factor on experimental colitis in the rat. J Pharmacol Exp Ther 1993; 264:984-90.
3. Konturek S, Dembinski A, Warzecha Z, et al. Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats. Gastroenterology 1988;94:1300-7.
4. Romano M, Polk WH, Awad JA, et al. Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo. J Clin Invest 1992;90:2409-21.
5. Polk WH, Jr, Dempsey PJ, Russell WE, et al. Increased production of transforming growth factor alpha following acute gastric injury. Gastroenterology 1992;102:1467-74.
6. Tarnawski A, Stachura J, Durbin T, et al. Increased expression of epidermal growth factor receptor during gastric ulcer healing in rats. Gastroenterology 1992;102:695-8.
7. Derynck R. The physiology of transforming growth factor-alpha. Adv Cancer Res 1992;58:27-52.
8. Carpenter G, Cohen S. Epidermal growth factor. Annu Rev Biochem 1979;48:193-216.
9. Derynck R, Roberts AB, Winkler ME, et al. Human transforming growth factor-alpha: precursor structure and expression in E. coli. Cell 1984;38:287-97.
10. Scott J, Urdea M, Quiroga M, et al. Structure of mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science 1983;221:236-40.
11. Bell GI, Fong NM, Stempien MM, et al. Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization. Nucleic Acids Res 1986;14: 8427-46.
12. Derynck R. Transforming growth factor-alpha. Mol Reprod Dev 1990;27:3-9.
13. Hsuan JJ, Panayotou G, Waterfield MD. Structural basis for epidermal growth factor receptor function. Progress in Growth Factor Research 1989;1:23-32.
14. Sottili M, Sternini C, Reinshagen M, et al. Up-regulation of transforming growth factor-alpha binding sites in experimental rabbit colitis. Gastroenterology 1995;109;24-31.
15. Hoffmann P, Zeeh JM, Lakshmanan J, et al. Increased expression of transforming growth factor alpha precursors in acute experimental colitis in rats. Gut 1997;41:195-202.
16. Egger B, Procaccino F, Lakshmanan J, et al. Mice lacking transforming growth factor-alpha have an increased susceptibility to dextran sulfate induced colitis. Gastroenterology 1997;113:825-32.
17. Perez-Tomas R, Cullere X, Asbert M, et al. Immunoelectron microscopic localisation of transforming growth factor alpha in rat colon. Gut 1994;35:1086-9.
18. Routtenberg A. Knockout mouse fault lines [letter]. Nature 1945;374:314-15.
19. Gerlai R. Gene-targeting studies of mammalian behaviour: is it the mutation or the background genotype? Trends Neurosci 1996;19:177-81.
20. Lathe R. Mice, gene targeting and behaviour: more than just genetic background. Trends Neurosci 1996;19:183-6; discussion 188-9.
21. Lazar LM, Blum M. Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-alpha mRNA in mouse brain by a quantitative nuclease protection assay. J Neurosci 1992;12:1688-97.
22. Gattone VH, Sherman DA, Hinton DA, et al. Epidermal growth factor in the neonatal mouse salivary gland and kidney. Biol Neonate 1992;61:54-67.
23. Watson AJ. The cell biology of blastocyst development. Mol Reprod Dev 1992;33:492-504.
24. Brown P, Lam R, Lakshmanan J, et al. Transforming growth factor alpha in developing rats. Am J Physiol 1990;259: E256-60.
25. Strandjord TP, Clark JG, Hodson WA, et al. Expression of transforming growth factor-alpha in mid-gestation human fetal lung. Am J Respir Cell Mol Biol 1993;8:266-72.
26. Burton PB, Quirke P, Sorensen CM, et al. Growth factor expression during rat development: a comparison of TGF-beta 3, TGF-alpha, bFGF, PDGF and PDGF-R. Int J Exp Pathol 1993;74:87-96.
27. Sandgren EP, Luetteke NC, Palmiter RD, et al. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990;61:1121-35.
28. Burgess AW, Knesel J, Sparrow LG, et al. Two forms of murine epidermal growth factor: rapid separation by using reverse-phase HPLC. Proc. Natl Acad Sci USA 1982;79: 5753-7.
29. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
30. Gratzner HG. Monoclonal antibody to 5-bromo- and 5-iododesoxyuridine: a new reagent for detection of DNA replication. Science 1982;218:474-7.
31. Lev R, Spicer SS. Specific staining of sulfate groups with alcian blue at low pH. J Histochem Cytochem 1964;12:309-11.
32. Okayasu I, Hatakeyama S, Yamada M, et al. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990;98:694-702.
33. Cooper HS, Murthy SNS, Shah RS, et al. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993;69:238-49.
34. Ni J, Chen SF, Hollander D. Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes. Gut 1996;39:234-41.
35. Takizawa H, Shintani N, Natsui M, et al. Activated immunocompetent cells in rat colitis mucosa induced by dextran sulfate sodium and not complete but partial suppression of colitis by FK506. Digestion 1995;56:259-64.
36. Leung FW, Heng MCY, Allen S, et al. Time course of immunological events in dextran sulfate sodium-induced colitis in rats: an immunohistochemical and ultrastructural study. Gastroenterology (suppl) 1997;112:A1026.
37. Ling K, Bhalla D, Hollander D. Mechanisms of carrageenan injury of IEC18 small intestinal epithelial cell monolayers. Gastroenterology 1908;95:1487-95.
38. Satoyoshi K, Akita Y, Nozu F, et al. Hemodynamics in the colonic mucosa of rats with dextran sulfate-induced colitis in the early phase J Gastroenterol 1996;31:512-17.
39. Onderdonk AB, Steeves RM, Cisneros RL, et al. Adoptive transfer of immune enhancement of experimental ulcerative colitis. Infect Imnitin 1084;46:64-7.
40. Breeling JL, Onderdonk AB, Cisneros RT, et al. Bacteroides vulgatus outer membrane antigens associated with carrageenan-induced colitis in guinea pigs. Infect Immun 1988;56:1754-9.
41. Luetteke NC, Qiu TH, Peiffer RL, et al. TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 1993;73:263-78.
42. Mann GB, Fowler KJ, Gabriel A, et al. Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 1993;73:249-61.
43. Babyatsky MW, Rossiter G, Podolsky DK. Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease. Gastroenterology 1996;110:975-84.
44. Takagi H, Jhappan C, Sharp R, et al. Hypertrophic gastropathy resembling Menetrier's disease in transgenic mice over expressing transforming growth factor alpha in the stomach. J Clin Invest 1992;90:1161-7.
45. Grisham MB, Von Ritter C, Smith BF, et al. Interaction between oxygen radicals and gastric mucin. Am J Physiol 1987;253:G93-6.
46. Mashimo H, Wu DC, Podolsky DK, et al. Impaired defence of intestinal mucosa in mice lacking intestinal trefoil factor. Science 1996;274:259-65.
47. Chinery R, Poulsom R, Rogers LA, et al. Localization of intestinal trefoil-factor mRNA in rat stomach and intestine by hybridization in situ. Biochem J 1992;285:5-8.
48. Kindon H, Pothoulakis C, Thim L, et al. Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein. Gastroenterology 1995;109:516-23.