-
1
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
3
-
-
0029020282
-
Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
-
(1995)
FASEB J
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
6
-
-
0028964465
-
Cytokine signaling through nonreceptor tyrosine kinases
-
(1995)
Science
, vol.268
, pp. 251-255
-
-
Taniguchi, T.1
-
25
-
-
0022401519
-
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
-
(1985)
Cell
, vol.43
, pp. 393-404
-
-
Marth, J.D.1
Peet, R.2
Krebs, E.G.3
-
32
-
-
0032541571
-
The many faces of Src: Multiple functions of a prototypical tyrosine kinase
-
(1998)
Oncogene
, vol.17
, pp. 1463-1468
-
-
Schwartzberg, P.L.1
-
34
-
-
0026727212
-
The p60c-src family of protein-tyrosine kinases: Structure, regulation, and function
-
(1992)
Crit Rev Oncog
, vol.3
, pp. 401-446
-
-
Brickell, P.M.1
-
44
-
-
0032875098
-
Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
-
(1999)
Biochim Biophys Acta
, vol.1451
, pp. 1-16
-
-
Resh, M.D.1
-
45
-
-
0022977712
-
A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps
-
(1986)
Mol Cell Biol
, vol.6
, pp. 4396-4408
-
-
Sadowski, I.1
Stone, J.C.2
Pawson, T.3
-
50
-
-
0029758089
-
Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: The intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated
-
(1996)
Biochemistry
, vol.35
, pp. 9519-9525
-
-
Boerner, R.J.1
Kassel, D.B.2
Barker, S.C.3
-
64
-
-
0031895351
-
The Hsp90-based chaperone system - Involvement in signal transduction from a variety of hormone and growth factor receptors
-
(1998)
Proc Soc Exp Biol Med
, vol.217
, pp. 420-434
-
-
Pratt, W.B.1
-
70
-
-
0028363670
-
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila
-
(1994)
Cell
, vol.77
, pp. 1027-1036
-
-
Cutforth, T.1
Rubin, G.M.2
-
78
-
-
0024478058
-
pp60c-src Tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1536-1544
-
-
Wilson, L.K.1
Luttrell, D.K.2
Parsons, J.T.3
-
79
-
-
0029904262
-
Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling
-
(1996)
J Biol Chem
, vol.271
, pp. 16798-16806
-
-
Broome, M.A.1
Hunter, T.2
-
80
-
-
0029975520
-
The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor
-
(1996)
J Biol Chem
, vol.271
, pp. 16807-16812
-
-
Erpel, T.1
Alonso, G.2
Roche, S.3
-
83
-
-
0031899815
-
Activation of Src family members is not required for the platelet-derived growth factor beta receptor to initiate mitogenesis
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2014-2022
-
-
DeMali, K.A.1
Kazlauskas, A.2
-
84
-
-
0033583220
-
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr(845) and Tyr(1101) is associated with modulation of receptor function
-
(1999)
J Biol Chem
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
-
90
-
-
0030734791
-
Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts
-
(1997)
J Clin Invest
, vol.100
, pp. 2476-2485
-
-
Insogna, K.L.1
Sahni, M.2
Grey, A.B.3
-
91
-
-
0033609922
-
Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src
-
(1999)
J Biol Chem
, vol.274
, pp. 25130-25135
-
-
He, H.1
Venema, V.J.2
Gu, X.3
-
93
-
-
0032475843
-
Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation
-
(1998)
J Biol Chem
, vol.273
, pp. 25777-25782
-
-
Chen, H.C.1
Chan, P.C.2
Tang, M.J.3
-
95
-
-
0032509402
-
c-Src Kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells
-
(1998)
J Biol Chem
, vol.273
, pp. 33714-33721
-
-
Rahimi, N.1
Hung, W.2
Tremblay, E.3
-
101
-
-
0033559439
-
Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src
-
(1999)
J Clin Invest
, vol.103
, pp. 789-797
-
-
Ishida, T.1
Ishida, M.2
Suero, J.3
-
104
-
-
0031438076
-
G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts - Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases
-
(1997)
J Biol Chem
, vol.272
, pp. 31648-31656
-
-
Luttrell, L.M.1
Daaka, Y.2
Dellarocca, G.J.3
-
106
-
-
0032483381
-
Involvement of protein kinase C and Src family tyrosine kinase in Galpha(q/11)-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase
-
(1998)
J Biol Chem
, vol.273
, pp. 22892-22898
-
-
Nagao, M.1
Yamauchi, J.2
Kaziro, Y.3
-
108
-
-
0032541410
-
Constitutive activation of delayed-rectifier potassium channels by a src family tyrosine kinase in Schwann cells
-
(1998)
EMBO J
, vol.17
, pp. 4723-4734
-
-
Sobko, A.1
Peretz, A.2
Attali, B.3
-
111
-
-
0033575279
-
Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases - Activation by rapsyn
-
(1999)
J Biol Chem
, vol.274
, pp. 20529-20539
-
-
Mohamed, A.S.1
Swope, S.L.2
-
118
-
-
0031921101
-
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2571-2585
-
-
Schlaepfer, D.D.1
Jones, K.C.2
Hunter, T.3
-
123
-
-
0028981376
-
Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix
-
(1995)
J Biol Chem
, vol.270
, pp. 22259-22262
-
-
Vuori, K.1
Ruoslahti, E.2
-
127
-
-
0030694182
-
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6906-6914
-
-
Richardson, A.1
Malik, R.K.2
Hildebrand, J.D.3
-
130
-
-
0032472411
-
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
-
(1998)
EMBO J
, vol.17
, pp. 81-92
-
-
Fincham, V.J.1
Frame, M.C.2
-
131
-
-
0032509402
-
c-Src Kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells
-
(1998)
J Biol Chem
, vol.273
, pp. 33714-33721
-
-
Rahimi, N.1
Hung, W.2
Tremblay, E.3
-
135
-
-
0030449827
-
Growth factors and the kidney: Regulation of epithelial cell movement and morphogenesis
-
(1996)
Am J Physiol
, vol.271
-
-
Cantley, L.G.1
-
137
-
-
8044248971
-
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: Cooperation between src and HGF/Met in invasion
-
(1997)
Br J Cancer
, vol.75
, pp. 241-250
-
-
Empereur, S.1
Djelloul, S.2
Di Gioia, Y.3
-
143
-
-
0030923190
-
Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties
-
(1997)
J Biol Chem
, vol.272
, pp. 14442-14446
-
-
Lu, T.T.1
Barreuther, M.2
Davis, S.3
-
150
-
-
0030740148
-
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
-
(1997)
Immunity
, vol.7
, pp. 69-81
-
-
Chan, V.W.1
Meng, F.2
Soriano, P.3
-
158
-
-
0030912071
-
Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn
-
(1997)
J Exp Med
, vol.185
, pp. 1661-1670
-
-
Meng, F.1
Lowell, C.A.2
-
172
-
-
0033025369
-
Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy: Progression from reversible to irreversible inhibitors
-
(1999)
Pharmacol Ther
, vol.82
, pp. 207-218
-
-
Fry, D.W.1
-
179
-
-
0031796005
-
Src homology-2 domains: Structure, mechanisms, and drug discovery
-
(1998)
Biopolymers
, vol.47
, pp. 243-261
-
-
Sawyer, T.K.1
-
191
-
-
0021932292
-
Screening of agents which convert 'transformed morphology' of Rous sarcomavirus-infected rat kidney cells to 'normal morphology': Identification of an active agent as herbimycin and its inhibition of intracellular src kinase
-
(1985)
Jpn J Cancer Res
, vol.76
, pp. 672-675
-
-
Uehara, Y.1
Hori, M.2
Takeuchi, T.3
-
192
-
-
0022967572
-
Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60Src in rat kidney cells infected with Rous sarcoma virus
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2198-2206
-
-
Uehara, Y.1
Hori, M.2
Takeuchi, T.3
-
195
-
-
0033564430
-
KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules
-
(1999)
Cancer Res
, vol.59
, pp. 2931-2938
-
-
Soga, S.1
Neckers, L.M.2
Schulte, T.W.3
-
196
-
-
0028912285
-
Paeciloquinones A, B, C, D, E and F: New potent inhibitors of protein tyrosine kinases produced by Paecilomyces carneus. I. Taxonomy, fermentation, isolation and biological activity
-
(1995)
J Antibiotics
, vol.48
, pp. 191-198
-
-
Petersen, F.1
Fredenhagen, A.2
Mett, H.3
-
209
-
-
0028104631
-
Synthesis and biochemical evaluation of a series of aminoflavones as potential inhibitors of protein-tyrosine kinases p56lck, EGFr, and p60v-src
-
(1994)
J Med Chem
, vol.37
, pp. 3353-3362
-
-
Cushman, M.1
Zhu, H.2
Geahlen, R.L.3
-
210
-
-
0028947501
-
Approach to the discovery of novel, selective inhibitors of p561ck tyrosine kinase: Identification of non-hydroxylated chromones as p56lck inhibitors
-
(1995)
Drug Dev Res
, vol.34
, pp. 344-352
-
-
Miller, D.1
Wang, S.2
Reid, J.3
-
216
-
-
0033538676
-
A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells: A novel candidate for prevention of vascular remodeling
-
(1999)
Circ Res
, vol.85
, pp. 12-22
-
-
Waltenberger, J.1
Uecker, A.2
Kroll, J.3
-
217
-
-
0033152210
-
Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors
-
(1999)
Structure
, vol.7
, pp. 651-661
-
-
Zhu, X.T.1
Kim, J.L.2
Newcomb, J.R.3
-
218
-
-
0007723656
-
-
Substituted 5,7-diphenyl-pyrrolo[2,3-d]pyrimidines: Potent and specific inhibitors of the tyrosine kinase pp60 c-Src. 215th ACS Natl Meet (March 29-April 2, Dallas) 1998, MEDI-168
-
(1998)
-
-
Missbach, M.1
Green, J.2
Susa, M.3
-
219
-
-
0032904762
-
A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo
-
(1999)
Bone
, vol.24
, pp. 437-449
-
-
Missbach, M.1
Jeschke, M.2
Feyen, J.3
-
223
-
-
15444353988
-
2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity
-
(1998)
J Med Chem
, vol.41
, pp. 3276-3292
-
-
Klutchko, S.R.1
Hamby, J.M.2
Boschelli, D.H.3
-
226
-
-
15644374929
-
Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines - Identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors
-
(1998)
J Med Chem
, vol.41
, pp. 4365-4377
-
-
Boscheili, D.H.1
Wu, Z.2
Klutchko, S.R.3
-
227
-
-
0007773117
-
-
Cytotoxicity and phosphotyrosine effects of c-src kinase inhibition by substituted pyridopyrimidine tyrosine kinase inhibitors in human colon carcinoma cell lines. 88th Annu Meet Am Assoc Cancer Res (April 12-16, San Diego) 1997: Abst 633
-
(1997)
, vol.38
-
-
Kraker, A.J.1
Moore, C.W.2
Amar, A.M.3
-
230
-
-
0007777154
-
-
The development of substituted 2-anilinopyrido(2,3-d)pyrimidines as novel, potent inhibitors of the c-src kinase receptor. 88th Annu Meet Am Assoc Cancer Res (April 12-16, San Diego) 1997: Abst 470
-
(1997)
, vol.38
-
-
Showalter, H.D.H.1
Klutchko, S.2
Boschelii, D.3
-
236
-
-
0027981473
-
Tyrosine kinase inhibitors. 3. Structure-activity relationships for inhibition of protein tyrosine kinases by nuclear-substituted derivatives of 2,2'-dithiobis(1-methyl-N-phenyl-1H-indole-3-carboxamide)
-
(1994)
J Med Chem
, vol.37
, pp. 2033-2042
-
-
Rewcastle, G.W.1
Palmer, B.D.2
Dobrusin, E.M.3
-
237
-
-
0029587403
-
Inhibition of basic fibroblast growth factor-mediated tyrosine phosphorylation and protein synthesis by PD 145709, a member of the 2-thioindole class of tyrosine kinase inhibitors
-
(1995)
Anticancer Drug Des
, vol.10
, pp. 607-622
-
-
Fry, D.W.1
Nelson, J.M.2
-
238
-
-
4644279756
-
Tyrosine kinase inhibitors. 6. Structure-activity relationships among N-and 3-substituted 2,2'-diselenobis(1H-indoles) for inhibition of protein tyrosine kinases and comparative in vitro and in vivo studies against selected sulfur congeners
-
(1997)
J Med Chem
, vol.40
, pp. 413-426
-
-
Showalter, H.D.H.1
Sercel, A.D.2
Leja, B.M.3
|