S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

EMBO Journal

Volumn 16, Issue 16, 1997, Pages 4983-4998

  Kabouridis, Panagiotis S ^a   Magee, Anthony I ^a   Ley, Steven C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

LCK; Localization; S acylation; Signalling

Indexed keywords

CALCIUM ION; CD69 ANTIGEN; CD8 ANTIGEN; HYBRID PROTEIN; MEMBRANE PROTEIN; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ACYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE; CHIMERA; CONTROLLED STUDY; ENZYME INDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ACYLATION; ANIMALS; ANTIGENS, CD8; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CELL MEMBRANE; CLONE CELLS; COS CELLS; ENZYME ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; PHOSPHOTYROSINE; PRECIPITIN TESTS; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; T-LYMPHOCYTES; TRANSFECTION; ZAP-70 PROTEIN-TYROSINE KINASE;

ANIMALIA;

EID: 0030746106     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.16.4983     Document Type: Article

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