Protein kinase C δ activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells

Diabetes

Volumn 52, Issue 4, 2003, Pages 991-997

  Eitel, Katrin ^a   Staiger, Harald ^a   Rieger, Johannes ^a   Mischak, Harald ^b   Brandhorst, Heide ^c   Brendel, Mathias D ^c   Bretzel, Reinhard G ^c   Häring, Hans Ulrich ^a   Kellerer, Monika ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; FATTY ACID; LAMIN B; LINOLEIC ACID; OLEIC ACID; PALMITIC ACID; PALMITOLEIC ACID; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE C DELTA; SATURATED FATTY ACID; STEARIC ACID;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; MOLECULAR MECHANICS; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CASPASE 3; CASPASES; CELL NUCLEUS; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; FATTY ACIDS; FATTY ACIDS, NONESTERIFIED; HUMANS; IN SITU NICK-END LABELING; INSULIN; INSULINOMA; ISLETS OF LANGERHANS; LAMIN TYPE B; LINOLEIC ACID; MUTATION; PALMITIC ACID; PANCREATIC NEOPLASMS; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; RATS; SIGNAL TRANSDUCTION; STEARIC ACIDS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037382424     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.4.991     Document Type: Article

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