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Volumn 45, Issue 1, 2002, Pages 85-96

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients

Author keywords

Islet amyloid; Islet pathology; Morphometry; Oxidative stress; Type II diabetes

Indexed keywords

AMYLOID; CONGO RED; COPPER; PROINSULIN; SUPEROXIDE DISMUTASE; ZINC;

EID: 0036163156     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s125-002-8248-z     Document Type: Article
Times cited : (563)

References (64)
  • 16
    • 0030467497 scopus 로고    scopus 로고
    • Prolonged exposure of human β cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation
    • (1996) J Clin Invest , vol.98 , pp. 2805-2812
    • Ling, Z.1    Pipeleers, D.G.2
  • 20
    • 0028019483 scopus 로고
    • Subtype of insulin-dependent diabetes mellitus (IDDM) in Japan: Slowly progressive IDDM- the clinical characterisitics and pathogenesis of the syndrome
    • (1994) Diabetes Res Clin Pract , vol.24 , Issue.SUPPL.
    • Kobayashi, T.1
  • 22
    • 0030948596 scopus 로고    scopus 로고
    • Quantitative immunohistochemical determination of 8-hydroxy-2′-deoxyguanosine by a monoclonal antibody N45.1: Its application to ferric nitrilotriacetate-induced renal carcinogenesis model
    • (1997) Lab Invest , vol.76 , pp. 365-374
    • Toyokuni, S.1    Tanaka, T.2    Hattori, Y.3
  • 45
    • 0034060985 scopus 로고    scopus 로고
    • Inhibition of progressive reduction of islet β-cell mass in spontaneously diabetic Goto-Kakizaki rats by α-glucosidase inhibitor
    • (2000) Metabolism , vol.49 , pp. 347-352
    • Koyama, M.1    Wada, R.2    Mizukami, H.3
  • 48
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 49
    • 0031693176 scopus 로고    scopus 로고
    • Lipid peroxidation and biogenic aldehydes: From the identification of 4-hydroxynonenal to further achievements in biopathology
    • (1998) Free Radic Res , vol.28 , pp. 623-635
    • Comporti, M.1
  • 54
    • 0032763487 scopus 로고    scopus 로고
    • Association between M/L55-polymorphism of paraxonase enzyme and oxidative DNA damage in patients with type 2 diabetes mellitus and in control subjects
    • (1999) Hum Genet , vol.105 , pp. 179-180
    • Malin, R.1    Rantalaiho, V.2    Huang, X.H.3
  • 56
    • 0033041916 scopus 로고    scopus 로고
    • Reactive oxygen species-induced molecular damage and its application in pathology
    • (1999) Pathol Int , vol.49 , pp. 91-102
    • Toyokuni, S.1
  • 58
    • 0031025828 scopus 로고    scopus 로고
    • Long term effects of aminoguanidine on insulin release and biosynthesis: Evidence that the formation of advanced glycosylation end products inhibit B cell function
    • (1997) Endocrinology , vol.138 , pp. 273-280
    • Tajiri, Y.1    Möller, C.2    Grill, V.3
  • 61
    • 0022448701 scopus 로고
    • Effect of vitamin E deficiency and selenium deficiency on insulin secretory reserve and free radical scavenging systems in islets: Decrease of islet mangan-superoxide dismutase
    • (1986) J Lab Clin Med , vol.107 , pp. 459-464
    • Asayama, K.1    Kooy, N.W.2    Burr, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.