Integrated decision-tree testing strategies for acute systemic toxicity and toxicokinetics with respect to the requirements of the EU REACH legislation

Alternatives to Laboratory Animals

Volumn 36, Issue SUPPL. 1, 2008, Pages 91-109

  Combes, Robert ^a   Grindon, Christina ^a   Cronin, Mark T D ^b   Roberts, David W ^b   Garrod, John F ^c  

^a RUSSELL AND BURCH HOUSE   (United Kingdom)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c DEFRA   (United Kingdom)

Author keywords

Acute toxicity; Animal testing; Decision trees; Defra; In silico models; In vitro testing; Integrated testing strategies; REACH; Risk assessment; Three rs; Toxicokinetics

Indexed keywords

ACUTE TOXICITY; ANIMAL TESTING ALTERNATIVE; COMPUTER MODEL; CYTOTOXICITY; IN VITRO STUDY; NONHUMAN; NOTE; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICITY TESTING; TOXICOKINETICS;

ANIMALIA;

EID: 85138944314     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803601s08     Document Type: Note

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