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Volumn 26, Issue 6, 1998, Pages 821-847

In Vitro Models of the Blood-Brain Barrier

Author keywords

Blood brain barrier; In vitro modelling; Permeability

Indexed keywords

BOVINAE;

EID: 0001450573     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (31)

References (138)
  • 1
    • 0031024172 scopus 로고    scopus 로고
    • Discrimination between drug candidates using models for evaluation of intestinal absorption
    • Stewart, B H., Chan, O.H., Jezyk, N & Fleisher, D. (1997) Discrimination between drug candidates using models for evaluation of intestinal absorption. Advanced Drug Delivery Reviews 23, 27-45.
    • (1997) Advanced Drug Delivery Reviews , vol.23 , pp. 27-45
    • Stewart, B.H.1    Chan, O.H.2    Jezyk, N.3    Fleisher, D.4
  • 2
    • 0031013760 scopus 로고    scopus 로고
    • Selection of development candidates based on in vitro permeability measurements
    • Lee, C-P., de Vrueh, R.L A. & Smith, P L. (1997). Selection of development candidates based on in vitro permeability measurements. Advanced Drug Delivery Reviews 23, 47-62.
    • (1997) Advanced Drug Delivery Reviews , vol.23 , pp. 47-62
    • Lee, C.-P.1    De Vrueh, R.L.A.2    Smith, P.L.3
  • 4
    • 0030588714 scopus 로고    scopus 로고
    • CaCo-2 monolayers in experimental and theoretical predictions of drug transport
    • Artursson, P , Palm, K & Luthman, K (1996). CaCo-2 monolayers in experimental and theoretical predictions of drug transport. Advanced Drug Delivery Reviews 22, 67-84.
    • (1996) Advanced Drug Delivery Reviews , vol.22 , pp. 67-84
    • Artursson, P.1    Palm, K.2    Luthman, K.3
  • 5
    • 0030990079 scopus 로고    scopus 로고
    • In vitro permeability across CaCo-2 cells (colonie) can predict in vivo (small intestinal) absorption in man: Fact or myth?
    • Yee, S (1997). In vitro permeability across CaCo-2 cells (colonie) can predict in vivo (small intestinal) absorption in man: fact or myth? Pharmacological Research 14, 763-766.
    • (1997) Pharmacological Research , vol.14 , pp. 763-766
    • Yee, S.1
  • 6
    • 0031544341 scopus 로고    scopus 로고
    • Brain drug delivery through the blood-brain barrier transport systems, attempted strategies and issues
    • Halmost, T , Santarromana, M., Herscovici, J. & Scherman, D. (1997). Brain drug delivery through the blood-brain barrier transport systems, attempted strategies and issues. S.T.P. Pharma Sciences 7, 37-42
    • (1997) S.T.P. Pharma Sciences , vol.7 , pp. 37-42
    • Halmost, T.1    Santarromana, M.2    Herscovici, J.3    Scherman, D.4
  • 7
    • 0028964164 scopus 로고
    • The blood-brain barrier, in vitro methods and toxicological applications
    • Walker, I. & Coleman, M. (1995). The blood-brain barrier, in vitro methods and toxicological applications Toxicology in Vitro 9, 191-204.
    • (1995) Toxicology in Vitro , vol.9 , pp. 191-204
    • Walker, I.1    Coleman, M.2
  • 8
    • 0030588582 scopus 로고    scopus 로고
    • Reconstitution of the blood-brain barrier in cell culture for studies of drug transport and metabolism
    • de Boer, A. & Breimer, D (1996). Reconstitution of the blood-brain barrier in cell culture for studies of drug transport and metabolism. Advanced Drug Delivery Reviews 22, 251-264.
    • (1996) Advanced Drug Delivery Reviews , vol.22 , pp. 251-264
    • De Boer, A.1    Breimer, D.2
  • 9
  • 10
    • 0030726198 scopus 로고    scopus 로고
    • Bioavauability and transport of peptides and peptide drugs into the brain
    • Egleton, R.D & Davis, T P. (1997) Bioavauability and transport of peptides and peptide drugs into the brain. Peptides 18, 1431-1439.
    • (1997) Peptides , vol.18 , pp. 1431-1439
    • Egleton, R.D.1    Davis, T.P.2
  • 11
    • 0001842719 scopus 로고    scopus 로고
    • Blood-brain barrier transport mechanisms
    • (ed. K.E.A. Welsch), San Diego, CA, USA: Academic Press
    • Pardridge, W M. (1997) Blood-brain barrier transport mechanisms In Primer on Cerebrovascular Diseases (ed. K.E.A. Welsch), pp. 21-25. San Diego, CA, USA: Academic Press.
    • (1997) Primer on Cerebrovascular Diseases , pp. 21-25
    • Pardridge, W.M.1
  • 12
    • 0028866623 scopus 로고
    • Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes
    • Brett, F., Mizisin, A., Powell, H. & Campbell, I. (1995). Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes. Journal of Neuropathology and Experimental Neurology 54, 766-775.
    • (1995) Journal of Neuropathology and Experimental Neurology , vol.54 , pp. 766-775
    • Brett, F.1    Mizisin, A.2    Powell, H.3    Campbell, I.4
  • 13
    • 0025031767 scopus 로고
    • Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats
    • Betz, A.L. & Coester, H.C. (1990). Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats. Stroke 21, 1199-1204.
    • (1990) Stroke , vol.21 , pp. 1199-1204
    • Betz, A.L.1    Coester, H.C.2
  • 15
    • 0030795802 scopus 로고    scopus 로고
    • Effect of tumor necrosis factor-α on the permeability of bovine brain microvessel endothelial cell monolayers
    • Anda, T , Yamashita, H., Khalid, H., Tsutsumi, F.H., Tokunaga, Y. & Shibata, S. (1997). Effect of tumor necrosis factor-α on the permeability of bovine brain microvessel endothelial cell monolayers. Neurological Research 19, 369-376.
    • (1997) Neurological Research , vol.19 , pp. 369-376
    • Anda, T.1    Yamashita, H.2    Khalid, H.3    Tsutsumi, F.H.4    Tokunaga, Y.5    Shibata, S.6
  • 16
    • 0025130782 scopus 로고
    • Angiotensin peptide regulation of fluid-phase endocytosis in brain microvessel endothelial cell monolayers
    • Guillot, F.L. & Audus, K.L. (1990). Angiotensin peptide regulation of fluid-phase endocytosis in brain microvessel endothelial cell monolayers. Journal of Cerebral Blood Flow and Metabolism 10, 827-834.
    • (1990) Journal of Cerebral Blood Flow and Metabolism , vol.10 , pp. 827-834
    • Guillot, F.L.1    Audus, K.L.2
  • 17
    • 0026024441 scopus 로고
    • Characterization of atrial natriuretic peptide receptors in brain microvessel endothelial cells
    • Whitson, P A , Huls, M H. & Sams, C.F. (1991). Characterization of atrial natriuretic peptide receptors in brain microvessel endothelial cells. Journal of Cell Physiology 146, 43-51.
    • (1991) Journal of Cell Physiology , vol.146 , pp. 43-51
    • Whitson, P.A.1    Huls, M.H.2    Sams, C.F.3
  • 18
    • 0030175606 scopus 로고    scopus 로고
    • Permeability of the blood-brain barrier by the bradykinin agonist, RMP-7: Evidence for a sensitive, auto-regulated, receptor-mediated system
    • Bartus, R.T., Elliott, P., Hayward, N., Dean, R., McEwen, E.L. & Fisher, S.K. (1996) Permeability of the blood-brain barrier by the bradykinin agonist, RMP-7: evidence for a sensitive, auto-regulated, receptor-mediated system. Immunopkarmacology 33, 270-278.
    • (1996) Immunopkarmacology , vol.33 , pp. 270-278
    • Bartus, R.T.1    Elliott, P.2    Hayward, N.3    Dean, R.4    McEwen, E.L.5    Fisher, S.K.6
  • 19
    • 0028171995 scopus 로고
    • Changes in brain microvessel endothelial cell monolayer permeability induced by adrenergic drugs
    • Borges, N , Shi, F., Azevedo, I & Audus, K.L. (1994). Changes in brain microvessel endothelial cell monolayer permeability induced by adrenergic drugs European Journal of Pharmacology 269, 243-248.
    • (1994) European Journal of Pharmacology , vol.269 , pp. 243-248
    • Borges, N.1    Shi, F.2    Azevedo, I.3    Audus, K.L.4
  • 21
    • 2542513348 scopus 로고    scopus 로고
    • Cross-talk between brain capillary endothelial cells and astrocytes. upregulation of the low density lipoprotein receptor at the blood-brain barrier
    • Dehouck, B., Fenart, L , Dehouck, M., Cecchelli, R. & Fruchart, J (1997). Cross-talk between brain capillary endothelial cells and astrocytes. upregulation of the low density lipoprotein receptor at the blood-brain barrier. Nutrition Metabolism and Cardiovascular Diseases 7, 225-230.
    • (1997) Nutrition Metabolism and Cardiovascular Diseases , vol.7 , pp. 225-230
    • Dehouck, B.1    Fenart, L.2    Dehouck, M.3    Cecchelli, R.4    Fruchart, J.5
  • 22
    • 0027291310 scopus 로고
    • Effect of astroghal degeneration on the blood-brain barrier to protein in neonatal rats
    • Krum, J.M. & Rosenstein, J M. (1993). Effect of astroghal degeneration on the blood-brain barrier to protein in neonatal rats. Brain Research-Development Brain Research 74, 41-50.
    • (1993) Brain Research-Development Brain Research , vol.74 , pp. 41-50
    • Krum, J.M.1    Rosenstein, J.M.2
  • 23
    • 0030803406 scopus 로고    scopus 로고
    • Transport and detoxication: Principles, approaches and perspectives for research on the blood-brain barrier
    • Aigner, A., Wolf, S. & Gassen, H. (.1997). Transport and detoxication: principles, approaches and perspectives for research on the blood-brain barrier. Angewandte Chemie - International Edition in English 36, 24-41
    • (1997) Angewandte Chemie - International Edition in English , vol.36 , pp. 24-41
    • Aigner, A.1    Wolf, S.2    Gassen, H.3
  • 24
    • 0028237336 scopus 로고
    • Adhesion and cytotoxicity of myelin basic protein-specific encephalitogenic T cells to normal and inflamed cerebral endothelial cells
    • Tsukada, N., Matsuda, M., Miyagi, K. & Yanagisawa, N. (1994). Adhesion and cytotoxicity of myelin basic protein-specific encephalitogenic T cells to normal and inflamed cerebral endothelial cells. Autoimmunity 17, 225-232.
    • (1994) Autoimmunity , vol.17 , pp. 225-232
    • Tsukada, N.1    Matsuda, M.2    Miyagi, K.3    Yanagisawa, N.4
  • 25
    • 0026480267 scopus 로고
    • Effects of the extracellular matrix on fetal choroid plexus epithelial cells: Changes in morphology and multicellular organization do not affect gene expression
    • Thomas, T., Stadler, E. & Dziadek, M. (1992). Effects of the extracellular matrix on fetal choroid plexus epithelial cells: changes in morphology and multicellular organization do not affect gene expression Experimental Cell Research 203, 198-213.
    • (1992) Experimental Cell Research , vol.203 , pp. 198-213
    • Thomas, T.1    Stadler, E.2    Dziadek, M.3
  • 28
    • 0029073495 scopus 로고
    • Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model
    • Joly, B, Fardel, O., Cecchelli, R , Chesné, C., Puozzo, C. & Guillouzo, A. (1995) Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model. Toxicology in Vitro 9, 357-364.
    • (1995) Toxicology in Vitro , vol.9 , pp. 357-364
    • Joly, B.1    Fardel, O.2    Cecchelli, R.3    Chesné, C.4    Puozzo, C.5    Guillouzo, A.6
  • 32
    • 0028281788 scopus 로고
    • In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitors
    • Saheki, A , Terasaki, T., Tamai, I. & Tsuji, A (1994). In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharmacological Research 11, 305-311
    • (1994) Pharmacological Research , vol.11 , pp. 305-311
    • Saheki, A.1    Terasaki, T.2    Tamai, I.3    Tsuji, A.4
  • 33
    • 0027464373 scopus 로고
    • Comparison of fluvastatin and lovastatin blood-brain barrier transfer using in vitro and in vivo methods
    • Guillot, F., Misslin, P & Lemaire, M (1993). Comparison of fluvastatin and lovastatin blood-brain barrier transfer using in vitro and in vivo methods Journal of Cardiovascular Pharmacology 21, 339-346.
    • (1993) Journal of Cardiovascular Pharmacology , vol.21 , pp. 339-346
    • Guillot, F.1    Misslin, P.2    Lemaire, M.3
  • 35
    • 0023633555 scopus 로고
    • Bovine brain nucrovessel endothelial cell monolayers as a model system for the blood-brain barrier
    • Audus, K & Borchardt, R (1987). Bovine brain nucrovessel endothelial cell monolayers as a model system for the blood-brain barrier Annals of the New York Academy of Sciences 507, 9-18.
    • (1987) Annals of the New York Academy of Sciences , vol.507 , pp. 9-18
    • Audus, K.1    Borchardt, R.2
  • 36
    • 0030791590 scopus 로고    scopus 로고
    • Endocytosis of horseradish peroxidase by brain microvascular and umbilical vein endothelial cells in culture: An ultrastructural and morphometric study
    • Defazio, G., Ribatti, D., Nico, B , Ricchiuti, F., De Salvia, R., Roncali, L & Livrea, P. (1997) Endocytosis of horseradish peroxidase by brain microvascular and umbilical vein endothelial cells in culture: an ultrastructural and morphometric study. Brain Research Bulletin 43, 467-472
    • (1997) Brain Research Bulletin , vol.43 , pp. 467-472
    • Defazio, G.1    Ribatti, D.2    Nico, B.3    Ricchiuti, F.4    De Salvia, R.5    Roncali, L.6    Livrea, P.7
  • 38
    • 0026329552 scopus 로고
    • Ultrastructural study of transcellular transport of native and cationized albumin in cultured goat brain microvascular endothelium
    • (corrected; published erratum appears in Journal of Neurocytology 22, 231, 1993).
    • Vorbrodt, A.W. & Trowbridge, R.S. (1991). Ultrastructural study of transcellular transport of native and cationized albumin in cultured goat brain microvascular endothelium (corrected; published erratum appears in Journal of Neurocytology 22, 231, 1993). Journal of Neurocvtology 20, 998-1006.
    • (1991) Journal of Neurocvtology , vol.20 , pp. 998-1006
    • Vorbrodt, A.W.1    Trowbridge, R.S.2
  • 39
    • 0028240140 scopus 로고
    • Measurement of blood-brain barner GLUT1 glucose transporter and actin mRNA by a quantitative polymerase chain reaction assay
    • Boado, R. & Pardridge, W. (1994). Measurement of blood-brain barner GLUT1 glucose transporter and actin mRNA by a quantitative polymerase chain reaction assay. Journal of Neurochemistry 62, 2085-2090.
    • (1994) Journal of Neurochemistry , vol.62 , pp. 2085-2090
    • Boado, R.1    Pardridge, W.2
  • 41
    • 0028225130 scopus 로고
    • Drug delivery via active transport at the blood-brain barrier II Investigation of monocarboxylic acid transport in vitro
    • Walker, I., Nicholls, D., Irwin, W. & Freeman, S. (1994) Drug delivery via active transport at the blood-brain barrier II Investigation of monocarboxylic acid transport in vitro. International Journal of Pharmacology 108, 225-232.
    • (1994) International Journal of Pharmacology , vol.108 , pp. 225-232
    • Walker, I.1    Nicholls, D.2    Irwin, W.3    Freeman, S.4
  • 43
    • 0029056457 scopus 로고
    • In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier
    • Ohmshi, T , Tamai, I, Sakanaka, K., Sakata, A., Yamashima, T., Yamashita, J. & Tsuji, A (1995). In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier. Biochemical Pharmacology 49, 1541-1544.
    • (1995) Biochemical Pharmacology , vol.49 , pp. 1541-1544
    • Ohmshi, T.1    Tamai, I.2    Sakanaka, K.3    Sakata, A.4    Yamashima, T.5    Yamashita, J.6    Tsuji, A.7
  • 45
    • 0030935855 scopus 로고    scopus 로고
    • Factors controlling T-cell migration across rat cerebral endothelium in vitro
    • Pryce, G . Male, D., Campbell, I. & Greenwood, J (1997) Factors controlling T-cell migration across rat cerebral endothelium in vitro. Journal of Neuroimmunology 75, 84-94.
    • (1997) Journal of Neuroimmunology , vol.75 , pp. 84-94
    • Pryce, G.1    Male, D.2    Campbell, I.3    Greenwood, J.4
  • 46
    • 0026502638 scopus 로고
    • The cerebral microvessels in culture: An update
    • Joó, F (1992). The cerebral microvessels in culture: an update Journal of Neurochemistry 58, 1-17
    • (1992) Journal of Neurochemistry , vol.58 , pp. 1-17
    • Joó, F.1
  • 48
    • 0031033003 scopus 로고    scopus 로고
    • Differential distribution of an endothehal barrier antigen between the pial and cortical microvessels of the rat
    • Cassella, J., Lawrenson, J , Lawrence, L. & Firth, J (1997) Differential distribution of an endothehal barrier antigen between the pial and cortical microvessels of the rat. Brain Research 744, 335-338.
    • (1997) Brain Research , vol.744 , pp. 335-338
    • Cassella, J.1    Lawrenson, J.2    Lawrence, L.3    Firth, J.4
  • 49
    • 0028250026 scopus 로고
    • Molecular biology of blood-brain barrier ontogenesis and function
    • Risau, W. (1994). Molecular biology of blood-brain barrier ontogenesis and function. Acta Neurochirurgica-Supplementum Wien 60, 109-112
    • (1994) Acta Neurochirurgica-Supplementum Wien , vol.60 , pp. 109-112
    • Risau, W.1
  • 50
    • 0028818229 scopus 로고
    • Species similarities and differences in pharmacokinetics
    • Lin, J.H. (1995). Species similarities and differences in pharmacokinetics. Drug Metabolism and Disposition 23, 1008-1021.
    • (1995) Drug Metabolism and Disposition , vol.23 , pp. 1008-1021
    • Lin, J.H.1
  • 51
    • 0028933154 scopus 로고
    • Localization of glucose transporter GLUT3 in brain comparison of rodent and dog using species-specific carboxyl-tenninal antisera
    • Gerhart, D Z., Leino, R.L., Borson, N.B., Taylor, W E., Gronlund, K.M., McCall, A.L. & Drewes, L.R. (1995). Localization of glucose transporter GLUT3 in brain comparison of rodent and dog using species-specific carboxyl-tenninal antisera. Neuroscience 66, 237-246.
    • (1995) Neuroscience , vol.66 , pp. 237-246
    • Gerhart, D.Z.1    Leino, R.L.2    Borson, N.B.3    Taylor, W.E.4    Gronlund, K.M.5    McCall, A.L.6    Drewes, L.R.7
  • 52
    • 0029761449 scopus 로고    scopus 로고
    • Characterization of the MDCK cell line for screening neurotoxicants
    • Veronesi, B. (1996). Characterization of the MDCK cell line for screening neurotoxicants. Neurotoxicology 17, 433-443.
    • (1996) Neurotoxicology , vol.17 , pp. 433-443
    • Veronesi, B.1
  • 54
    • 0025988421 scopus 로고
    • Endothelial cells from human fetal brain microvessels may be cholinoceptive, but do not synthesize acetylcholine
    • Kasa, P., Pakaski, M., Joó, F. & Lajtha, A. (1991). Endothelial cells from human fetal brain microvessels may be cholinoceptive, but do not synthesize acetylcholine. Journal of Neurochemistry 56, 2143-2146.
    • (1991) Journal of Neurochemistry , vol.56 , pp. 2143-2146
    • Kasa, P.1    Pakaski, M.2    Joó, F.3    Lajtha, A.4
  • 55
    • 0025735082 scopus 로고
    • Culture and characterization of microvascular endothelial cells derived from human brain
    • Dorovini-Zis, K , Prameya, R & Bowman, P D. (1991) Culture and characterization of microvascular endothelial cells derived from human brain. Laboratory Investigations 64, 425-436
    • (1991) Laboratory Investigations , vol.64 , pp. 425-436
    • Dorovini-Zis, K.1    Prameya, R.2    Bowman, P.D.3
  • 56
    • 0028106829 scopus 로고
    • Biochemical characteristics of primary and passaged cultures of primate brain microvessel endothelial cells
    • Shi, F & Audus, K L. (1994) Biochemical characteristics of primary and passaged cultures of primate brain microvessel endothelial cells. Neurochemical Research 19, 427-433.
    • (1994) Neurochemical Research , vol.19 , pp. 427-433
    • Shi, F.1    Audus, K.L.2
  • 57
    • 0030579090 scopus 로고    scopus 로고
    • Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains
    • Teifel, M. & Friedl, P. (1996) Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains. Experimental Cell Research 228, 50-57.
    • (1996) Experimental Cell Research , vol.228 , pp. 50-57
    • Teifel, M.1    Friedl, P.2
  • 59
    • 0027972036 scopus 로고
    • Leucine enkephalin effects on paracellular and transcellular permeation pathways across brain microvessel endothelial cell monolayers
    • Thompson, S E., Cavitt, J & Audus, K.L (1994). Leucine enkephalin effects on paracellular and transcellular permeation pathways across brain microvessel endothelial cell monolayers Journal of Cardiovascular Pharmacology 24, 818-825
    • (1994) Journal of Cardiovascular Pharmacology , vol.24 , pp. 818-825
    • Thompson, S.E.1    Cavitt, J.2    Audus, K.L.3
  • 60
    • 0027499490 scopus 로고
    • Applications of primary cultures of brain microvessel endothelial cell monolayers in the study of vasoactive peptide interaction with the blood/brain barrier
    • Reardon, P & Audus, K (1993). Applications of primary cultures of brain microvessel endothelial cell monolayers in the study of vasoactive peptide interaction with the blood/brain barrier. S.T P. Pharmaceutical Sciences 3, 63-68.
    • (1993) S.T P. Pharmaceutical Sciences , vol.3 , pp. 63-68
    • Reardon, P.1    Audus, K.2
  • 61
    • 0025955209 scopus 로고
    • Catecholammes stimulate the IFN-γ-induced class II MHC expression on bovine brain capillary endothelial cells
    • Coutinho, G C , Durieu Trautmann, O., Strosberg, A D & Couraud, P O. (1991) Catecholammes stimulate the IFN-γ-induced class II MHC expression on bovine brain capillary endothelial cells Journal of Immunology 147, 2525-2529.
    • (1991) Journal of Immunology , vol.147 , pp. 2525-2529
    • Coutinho, G.C.1    Durieu Trautmann, O.2    Strosberg, A.D.3    Couraud, P.O.4
  • 62
    • 0031544403 scopus 로고    scopus 로고
    • Development and characterization of cellular models of the blood-brain barrier
    • Lechardeur, D , Scherman, D & Schwartz, B. (1997) Development and characterization of cellular models of the blood-brain barrier S.T.P. Pharmaceutical Sciences 7, 5-11.
    • (1997) S.T.P. Pharmaceutical Sciences , vol.7 , pp. 5-11
    • Lechardeur, D.1    Scherman, D.2    Schwartz, B.3
  • 63
    • 0027214117 scopus 로고
    • Aluminium-induced alteration of surface anionic sites in cultured brain microvascular endothelial cells
    • Vorbrodt, A. & Trowbridge, R (1993). Aluminium-induced alteration of surface anionic sites in cultured brain microvascular endothelial cells. Acta Neuropathoiogica 86, 371-377.
    • (1993) Acta Neuropathoiogica , vol.86 , pp. 371-377
    • Vorbrodt, A.1    Trowbridge, R.2
  • 64
    • 0025814669 scopus 로고
    • Correlation of zonula occludens ZO-1 antigen expression and transendothelial resistance in porcine and rat cultured cerebral endothelial cells
    • Krause, D., Mischeck, U., Galla, H J. & Dermietzel, R. (1991). Correlation of zonula occludens ZO-1 antigen expression and transendothelial resistance in porcine and rat cultured cerebral endothelial cells. Neuroscience Letters 128, 301-304.
    • (1991) Neuroscience Letters , vol.128 , pp. 301-304
    • Krause, D.1    Mischeck, U.2    Galla, H.J.3    Dermietzel, R.4
  • 65
    • 0026793292 scopus 로고
    • Development and characterisation of a rat brain capillary endothelial culture: Towards an in vitro blood-brain barrier
    • Abbott, N., Hughes, C., Revest, P. & Greenwood, J. (1992). Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier. Journal of Cell Science 103, 23-37.
    • (1992) Journal of Cell Science , vol.103 , pp. 23-37
    • Abbott, N.1    Hughes, C.2    Revest, P.3    Greenwood, J.4
  • 66
    • 0030248120 scopus 로고    scopus 로고
    • Biochemical characteristics of a primary blood-brain barrier cell culture system as a function of the activity of the proteases used in tissue disaggregation
    • Ng, K.Y. & Schallenkemp, J M. (1996). Biochemical characteristics of a primary blood-brain barrier cell culture system as a function of the activity of the proteases used in tissue disaggregation. Journal of Neuroscience Methods 68, 49-53.
    • (1996) Journal of Neuroscience Methods , vol.68 , pp. 49-53
    • Ng, K.Y.1    Schallenkemp, J.M.2
  • 67
    • 0025758380 scopus 로고
    • Purification and characterization of metabolically active capillaries of the blood-brain barrier
    • Dallaire, L., Tremblay, L. & Beliveau, R. (1991). Purification and characterization of metabolically active capillaries of the blood-brain barrier. Biochemical Journal 276, 745-752.
    • (1991) Biochemical Journal , vol.276 , pp. 745-752
    • Dallaire, L.1    Tremblay, L.2    Beliveau, R.3
  • 68
    • 0030939156 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor on receptor-mediated endocytosis and barrier functions of bovine brain capillary endothelial cell monolayers
    • Descamps, L., Cecchelli, R. & Torpier, G. (1997). Effects of tumor necrosis factor on receptor-mediated endocytosis and barrier functions of bovine brain capillary endothelial cell monolayers. Journal of Neuroimmunology 74, 173-184.
    • (1997) Journal of Neuroimmunology , vol.74 , pp. 173-184
    • Descamps, L.1    Cecchelli, R.2    Torpier, G.3
  • 70
    • 0026638367 scopus 로고
    • Permeability of bovine brain microvessel endothelial cells in vitro: Barrier tightening by a factor released from astroglioma cells
    • Raub, T J , Kuentzel, S. L. & Sawada, G A. (1992). Permeability of bovine brain microvessel endothelial cells in vitro: barrier tightening by a factor released from astroglioma cells. Experimental Cell Research 199, 330-430.
    • (1992) Experimental Cell Research , vol.199 , pp. 330-430
    • Raub, T.J.1    Kuentzel, S.L.2    Sawada, G.A.3
  • 72
    • 0028813087 scopus 로고
    • Contraction of human brain endothelial cells induced by thrombogenic and fibrinolytic factors an in vitro cell culture model
    • Nagy, Z., Kolev, K., Csonka, E., Pek, M. & Machovich, R. (1995). Contraction of human brain endothelial cells induced by thrombogenic and fibrinolytic factors an in vitro cell culture model. Stroke 26, 265-270.
    • (1995) Stroke , vol.26 , pp. 265-270
    • Nagy, Z.1    Kolev, K.2    Csonka, E.3    Pek, M.4    Machovich, R.5
  • 73
    • 0031041760 scopus 로고    scopus 로고
    • Hypothalamic extract influences a blood-brain barrier model of porcine brain capillary endothelial cells
    • Guerin, J.L. & Bobilya, D.J (1997) Hypothalamic extract influences a blood-brain barrier model of porcine brain capillary endothelial cells. Neurochemical Research 22, 321-326.
    • (1997) Neurochemical Research , vol.22 , pp. 321-326
    • Guerin, J.L.1    Bobilya, D.J.2
  • 74
    • 0027932917 scopus 로고
    • Plasminogen activator inhibitor-1 expression by brain microvessel endothelial cells is inhibited by elevated glucose
    • Kollros, P., Konkle, B , Ambarian, A. & Henrikson, P. (1994) Plasminogen activator inhibitor-1 expression by brain microvessel endothelial cells is inhibited by elevated glucose. Journal of Neurochemistry 63, 903-909
    • (1994) Journal of Neurochemistry , vol.63 , pp. 903-909
    • Kollros, P.1    Konkle, B.2    Ambarian, A.3    Henrikson, P.4
  • 75
    • 0029893476 scopus 로고    scopus 로고
    • Synergistic stimulation of γ-glutamyl transpeptidase and alkaline phosphatase activities by retinoic acid and astroglial factors in immortalized rat brain microvessel endothelial cells
    • el Hafny, B., Bourre, J M. & Roux, F. (1996). Synergistic stimulation of γ-glutamyl transpeptidase and alkaline phosphatase activities by retinoic acid and astroglial factors in immortalized rat brain microvessel endothelial cells. Journal of Cellular Physiology 167, 451-160.
    • (1996) Journal of Cellular Physiology , vol.167 , pp. 451-1160
    • El Hafny, B.1    Bourre, J.M.2    Roux, F.3
  • 76
    • 0029143996 scopus 로고
    • Induction of blood-brain barrier differentiation in a rat brain-derived endothehal cell line
    • Lechardeur, D , Schwartz, B., Paulin, D. & Scherman, D. (1995). Induction of blood-brain barrier differentiation in a rat brain-derived endothehal cell line Experimental Cell Research 220, 161-170
    • (1995) Experimental Cell Research , vol.220 , pp. 161-170
    • Lechardeur, D.1    Schwartz, B.2    Paulin, D.3    Scherman, D.4
  • 77
    • 0029671023 scopus 로고    scopus 로고
    • Endothelial cell GlcNAcβ1-4GlcNAc epitopes for outer membrane protein A enhance traversai of Escherichia coli across the blood-brain barrier
    • Prasadarao, N., Wass, C. & Kwang-Sik, K. (1996). Endothelial cell GlcNAcβ1-4GlcNAc epitopes for outer membrane protein A enhance traversai of Escherichia coli across the blood-brain barrier. Infection and Immunity 64, 154-160.
    • (1996) Infection and Immunity , vol.64 , pp. 154-160
    • Prasadarao, N.1    Wass, C.2    Kwang-Sik, K.3
  • 78
    • 0029918150 scopus 로고    scopus 로고
    • Astroglial cells inhibit the increasing permeability of brain endothelial cell monolayer following hypoxia/reoxygenation
    • Kondo, T., Kinouchi, H., Kawase, M. & Yoshimoto, T. (1996). Astroglial cells inhibit the increasing permeability of brain endothelial cell monolayer following hypoxia/reoxygenation. Neuroscience Letters 208, 101-104.
    • (1996) Neuroscience Letters , vol.208 , pp. 101-104
    • Kondo, T.1    Kinouchi, H.2    Kawase, M.3    Yoshimoto, T.4
  • 79
    • 0025285170 scopus 로고
    • Immune function of the blood-brain barrier: Incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro
    • Risau, W , Engelhardt, B. & Wekerle, H. (1990). Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro. Journal of Cell Biology 110, 1757-1766.
    • (1990) Journal of Cell Biology , vol.110 , pp. 1757-1766
    • Risau, W.1    Engelhardt, B.2    Wekerle, H.3
  • 81
    • 85047692688 scopus 로고
    • Induction of the blood-brain barrier-associated enzyme alkaline phosphatase in endothelial cells from cerebral capillaries is mediated via cAMP
    • Beuckmann, C., Hellwig, S. & Galla, H.J. (1995). Induction of the blood-brain barrier-associated enzyme alkaline phosphatase in endothelial cells from cerebral capillaries is mediated via cAMP. European Journal of Biochemistry 229, 641-644.
    • (1995) European Journal of Biochemistry , vol.229 , pp. 641-644
    • Beuckmann, C.1    Hellwig, S.2    Galla, H.J.3
  • 82
    • 0025787802 scopus 로고
    • The susceptibility of cerebral endothelial cells to astroglial induction of blood-brain barrier enzymes depends on their proliferative state
    • Meyer, J., Rauh, J. & Galla, H.J. (1991). The susceptibility of cerebral endothelial cells to astroglial induction of blood-brain barrier enzymes depends on their proliferative state. Journal of Neurochemistry 57, 1971-1977.
    • (1991) Journal of Neurochemistry , vol.57 , pp. 1971-1977
    • Meyer, J.1    Rauh, J.2    Galla, H.J.3
  • 84
    • 0029775029 scopus 로고    scopus 로고
    • Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions
    • Raub, T.J. (1996). Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions. American Journal of Physiology - Cell Physiology 271, 495-503.
    • (1996) American Journal of Physiology - Cell Physiology , vol.271 , pp. 495-503
    • Raub, T.J.1
  • 85
    • 0026756351 scopus 로고
    • Development of an in vitro cell culture system to mimic the blood-brain barrier
    • Raub, J., Meyer, J., Beuckmann, C. & Galla, H.J. (1992). Development of an in vitro cell culture system to mimic the blood-brain barrier. Progress in Brain Research 91, 117-121
    • (1992) Progress in Brain Research , vol.91 , pp. 117-121
    • Raub, J.1    Meyer, J.2    Beuckmann, C.3    Galla, H.J.4
  • 86
    • 0025265046 scopus 로고
    • An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro
    • Dehouck, M., Meresse, S., Delorme, P , Fruchart, J. & Cecchelli, R. (1990). An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro Journal of Neurochemistry 54, 1798-1801.
    • (1990) Journal of Neurochemistry , vol.54 , pp. 1798-1801
    • Dehouck, M.1    Meresse, S.2    Delorme, P.3    Fruchart, J.4    Cecchelli, R.5
  • 87
  • 88
    • 0027285199 scopus 로고
    • Crude liver membrane fractions and extracellular matrix components as substrata regulate differentially the preservation and inducibility of cytochrome P450 isoenzymes in cultured rat hepatocytes
    • Saad, B., Scholl, F., Thomas, H., Schawalder, H., Streit, V, Waechter, F. & Maier, P (1993). Crude liver membrane fractions and extracellular matrix components as substrata regulate differentially the preservation and inducibility of cytochrome P450 isoenzymes in cultured rat hepatocytes. European Journal of Biochemistry 213, 805-814.
    • (1993) European Journal of Biochemistry , vol.213 , pp. 805-814
    • Saad, B.1    Scholl, F.2    Thomas, H.3    Schawalder, H.4    Streit, V.5    Waechter, F.6    Maier, P.7
  • 90
    • 0027092617 scopus 로고
    • Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
    • Hegmann, E.J., Bauer, H C & Kerbel, R.S. (1992). Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells Cancer Research 52, 6969-6975
    • (1992) Cancer Research , vol.52 , pp. 6969-6975
    • Hegmann, E.J.1    Bauer, H.C.2    Kerbel, R.S.3
  • 92
    • 0030468826 scopus 로고    scopus 로고
    • Regulation of brain capillary endothelial thrombomodulin mRNA expression
    • Tran, N.D., Wong, V L., Schreiber, S.S., Bready, J. V. & Fisher, M. (1996). Regulation of brain capillary endothelial thrombomodulin mRNA expression. Stroke 27, 2304-2311.
    • (1996) Stroke , vol.27 , pp. 2304-2311
    • Tran, N.D.1    Wong, V.L.2    Schreiber, S.S.3    Bready, J.V.4    Fisher, M.5
  • 93
    • 0028923940 scopus 로고
    • Adhesion of lymphocytes to endothelial cells in experimental allergic encephalomyelitis before and after treatment with endotoxin lipopolysaecharide
    • Matsuda, M., Tsukada, N., Miyagi, K. & Yanagisawa, N. (1995). Adhesion of lymphocytes to endothelial cells in experimental allergic encephalomyelitis before and after treatment with endotoxin lipopolysaecharide. International Archives of Allergy and Immunology 106, 335-344.
    • (1995) International Archives of Allergy and Immunology , vol.106 , pp. 335-344
    • Matsuda, M.1    Tsukada, N.2    Miyagi, K.3    Yanagisawa, N.4
  • 94
    • 0027869687 scopus 로고
    • Cloned mouse cerebrovascular endothelial cells that maintain their differentiation markers for factor VIII, low density lipoprotein, and angiotensin-converting enzyme
    • Sapatino, B.V., Welsh, C.J , Smith, C A., Bebo, B.F & Linthicum, DS (1993) Cloned mouse cerebrovascular endothelial cells that maintain their differentiation markers for factor VIII, low density lipoprotein, and angiotensin-converting enzyme. In Vitro Cellular and Developmental Biology - Animal 29, 923-928
    • (1993) In Vitro Cellular and Developmental Biology - Animal , vol.29 , pp. 923-928
    • Sapatino, B.V.1    Welsh, C.J.2    Smith, C.A.3    Bebo, B.F.4    Linthicum, D.S.5
  • 95
    • 0025915770 scopus 로고
    • In vitro interaction of astrocytes and pericytes with capillary-like structures of brain microvessel endothelium
    • Minakawa, T., Bready, J., Berliner, J., Fisher, M. & Cancilla, P.A. (1991). In vitro interaction of astrocytes and pericytes with capillary-like structures of brain microvessel endothelium. Laboratory Investigations 65, 32-40.
    • (1991) Laboratory Investigations , vol.65 , pp. 32-40
    • Minakawa, T.1    Bready, J.2    Berliner, J.3    Fisher, M.4    Cancilla, P.A.5
  • 96
    • 0029049342 scopus 로고
    • Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro
    • Biegel, D , Spencer, D D & Pachter, J.S. (1995). Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro Brain Research 692, 183-189.
    • (1995) Brain Research , vol.692 , pp. 183-189
    • Biegel, D.1    Spencer, D.D.2    Pachter, J.S.3
  • 97
    • 0029759938 scopus 로고    scopus 로고
    • A dynamic model of the blood-brain barrier in uitro
    • Stanness, K.A., Guatteo, E. & Janigro, D. (1996). A dynamic model of the blood-brain barrier in uitro. Neurotoxicology 17, 481-496.
    • (1996) Neurotoxicology , vol.17 , pp. 481-496
    • Stanness, K.A.1    Guatteo, E.2    Janigro, D.3
  • 98
    • 0024325094 scopus 로고
    • The application of bovine brain microvessel endothelial cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
    • Shah, MV, Audus, K,L & Borchardt, R T. (1989), The application of bovine brain microvessel endothelial cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier Pharmacological Research 6, 624-627.
    • (1989) Pharmacological Research , vol.6 , pp. 624-627
    • Shah, M.V.1    Audus, K.L.2    Borchardt, R.T.3
  • 99
    • 0028015618 scopus 로고
    • Growth of brain microvessel endothelial cells on collagen gels: Applications to the study of blood-brain barrier physiology and CNS inflammation
    • Biegel, D. & Pachter, J S. (1994). Growth of brain microvessel endothelial cells on collagen gels: applications to the study of blood-brain barrier physiology and CNS inflammation. In Vitro Cellular and Developmental Biology - Animals 30, 581-588.
    • (1994) In Vitro Cellular and Developmental Biology - Animals , vol.30 , pp. 581-588
    • Biegel, D.1    Pachter, J.S.2
  • 100
    • 0029037256 scopus 로고
    • Attempted induction of blood-brain barrier in vitro by co-culture of gerbil brain microvessel endothehal cells and glial cells
    • Aiba, T (1995) Attempted induction of blood-brain barrier in vitro by co-culture of gerbil brain microvessel endothehal cells and glial cells. Neurologia Medico Chirurgica-Tokyo 35, 347-352
    • (1995) Neurologia Medico Chirurgica-Tokyo , vol.35 , pp. 347-352
    • Aiba, T.1
  • 101
    • 0027166030 scopus 로고
    • Characterisation of a γ-glutamyl transpeptidase positive subpopulation of endothelial cells in a spontaneous tube-forming clone of rat cerebral resistance-vessel endothehum
    • Wang, B., Grammas, P & De Bault, L. (1993). Characterisation of a γ-glutamyl transpeptidase positive subpopulation of endothelial cells in a spontaneous tube-forming clone of rat cerebral resistance-vessel endothehum Journal of Cellular Physiology 156, 531-540.
    • (1993) Journal of Cellular Physiology , vol.156 , pp. 531-540
    • Wang, B.1    Grammas, P.2    De Bault, L.3
  • 102
    • 0030560709 scopus 로고    scopus 로고
    • Sv40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics
    • Greenwood, J., Pryce, G , Devine, L., Male, D.K., Dossantos, W L.C , Calder, V L. & Adamson, P. (1996). Sv40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics. Journal of Neuroimmunology 71, 51-63
    • (1996) Journal of Neuroimmunology , vol.71 , pp. 51-63
    • Greenwood, J.1    Pryce, G.2    Devine, L.3    Male, D.K.4    Dossantos, W.L.C.5    Calder, V.L.6    Adamson, P.7
  • 104
    • 0030591795 scopus 로고    scopus 로고
    • Ethanol potentiates lipopolysaccharide-or interleukin-1-induced nitric oxide generation in RBE4 cells
    • Naassila, M , Roux, F., Beauge, F. & Daoust, M. (1996). Ethanol potentiates lipopolysaccharide-or interleukin-1-induced nitric oxide generation in RBE4 cells. European Journal of Pharmacology 313, 273-277.
    • (1996) European Journal of Pharmacology , vol.313 , pp. 273-277
    • Naassila, M.1    Roux, F.2    Beauge, F.3    Daoust, M.4
  • 105
    • 0030603137 scopus 로고    scopus 로고
    • Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo
    • Nam, M., Johnston, P., Lal, B., Indurti, R., Wilson, M. & Laterra, J. (1996). Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo. Brain Research 731, 161-170.
    • (1996) Brain Research , vol.731 , pp. 161-170
    • Nam, M.1    Johnston, P.2    Lal, B.3    Indurti, R.4    Wilson, M.5    Laterra, J.6
  • 106
    • 0030908906 scopus 로고    scopus 로고
    • Glucose transport in immortalized rat brain capillary endothelial cells in vitro: Transport activity and GLUT1 expression
    • Regina, A., Roux, F. & Revest, P.A. (1997). Glucose transport in immortalized rat brain capillary endothelial cells in vitro: transport activity and GLUT1 expression. Biochimica et Biophysica Acta 1335, 135-143
    • (1997) Biochimica et Biophysica Acta , vol.1335 , pp. 135-143
    • Regina, A.1    Roux, F.2    Revest, P.A.3
  • 107
    • 0030940277 scopus 로고    scopus 로고
    • Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells
    • Romero, I.A., Rist, R J , Aleshaiker, A. & Abbott, N J. (1997) Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells. Brain Research 756, 133-140.
    • (1997) Brain Research , vol.756 , pp. 133-140
    • Romero, I.A.1    Rist, R.J.2    Aleshaiker, A.3    Abbott, N.J.4
  • 109
    • 0025871202 scopus 로고
    • Production of a transforming growth factor-β-like factor by RSV-transformed rat cerebral microvascular endothelial cells
    • Mooradian, D L & Diglio, C A. (1991) Production of a transforming growth factor-β-like factor by RSV-transformed rat cerebral microvascular endothelial cells Tumour Biology 12, 171-183.
    • (1991) Tumour Biology , vol.12 , pp. 171-183
    • Mooradian, D.L.1    Diglio, C.A.2
  • 110
    • 2542554419 scopus 로고    scopus 로고
    • Characterization of the efflux transport systems for glutathione conjugates at the blood-brain barrier
    • 19-21 February 1998 Bethesda, MD, USA. NIH
    • Honma, M., Kusuhara, H., Suzuki, H , Naitou, M , Tsuruo, T. & Sugiyama, Y. (1998) Characterization of the efflux transport systems for glutathione conjugates at the blood-brain barrier First AAPS Frontier Symposium, 19-21 February 1998 Bethesda, MD, USA. NIH.
    • (1998) First AAPS Frontier Symposium
    • Honma, M.1    Kusuhara, H.2    Suzuki, H.3    Naitou, M.4    Tsuruo, T.5    Sugiyama, Y.6
  • 113
    • 0029941382 scopus 로고    scopus 로고
    • Astrocytic contributions to blood-brain barrier (BBB) formation by endothelial cells a possible use of aortic endothelial cells for in. vitro BBB model
    • Isobe, I, Watanabe, T , Yotsuyanagi, T., Hazemoto, N , Yamagata, K , Ueki, T., Nakamshi, K., Asai, K & Kato, T (1996) Astrocytic contributions to blood-brain barrier (BBB) formation by endothelial cells a possible use of aortic endothelial cells for in. vitro BBB model. Neurochemistry International 28, 523-533
    • (1996) Neurochemistry International , vol.28 , pp. 523-533
    • Isobe, I.1    Watanabe, T.2    Yotsuyanagi, T.3    Hazemoto, N.4    Yamagata, K.5    Ueki, T.6    Nakamshi, K.7    Asai, K.8    Kato, T.9
  • 114
    • 0028130532 scopus 로고
    • A comparison of drug transport through cultured monolayers of bovine brain capillary and bovine aortic endothelial cells
    • Mizuguchi, H , Hashioka, Y , Utoguchi, N , Kubo, K , Nakagawa, S. & Mayumi, T (1994) A comparison of drug transport through cultured monolayers of bovine brain capillary and bovine aortic endothelial cells Biological and Pharmaceutical Bulletin 17, 1385-1390
    • (1994) Biological and Pharmaceutical Bulletin , vol.17 , pp. 1385-1390
    • Mizuguchi, H.1    Hashioka, Y.2    Utoguchi, N.3    Kubo, K.4    Nakagawa, S.5    Mayumi, T.6
  • 115
    • 0023751255 scopus 로고
    • Use of an in vitro system to study the effects of lead on astrocyte-endothelial cell interactions, a model for studying toxic injury to the blood-brain barrier
    • Gebhart, A. & Goldstein. G (1988) Use of an in vitro system to study the effects of lead on astrocyte-endothelial cell interactions, a model for studying toxic injury to the blood-brain barrier Toxicology and Applied Pharmacology 94, 191-206.
    • (1988) Toxicology and Applied Pharmacology , vol.94 , pp. 191-206
    • Gebhart, A.1    Goldstein, G.2
  • 116
    • 0029983527 scopus 로고    scopus 로고
    • Properties of an immortalised vascular endothelial/glioma cell coculture model of the blood-brain barrier
    • Hurst, R.D & Fritz, I.E. (1996). Properties of an immortalised vascular endothelial/glioma cell coculture model of the blood-brain barrier. Journal of Cellular Physiology 167, 81-88.
    • (1996) Journal of Cellular Physiology , vol.167 , pp. 81-88
    • Hurst, R.D.1    Fritz, I.E.2
  • 117
    • 0029933293 scopus 로고    scopus 로고
    • Nitric oxide-induced perturbations in a cell culture model of the blood-brain barrier
    • Hurst, R. & Fritz, I. (1996). Nitric oxide-induced perturbations in a cell culture model of the blood-brain barrier. Journal of Cellular Physiology 167, 89-94.
    • (1996) Journal of Cellular Physiology , vol.167 , pp. 89-94
    • Hurst, R.1    Fritz, I.2
  • 118
    • 0030955124 scopus 로고    scopus 로고
    • Molecular characteristics of pial microvessels of the rat optic nerve Can pial microvessels be used as a model for the blood-brain barrier?
    • Lawrenson, J.G., Reid, A.R. & Allt, G. (1997). Molecular characteristics of pial microvessels of the rat optic nerve Can pial microvessels be used as a model for the blood-brain barrier? Cell and Tissue Research 288, 259-265.
    • (1997) Cell and Tissue Research , vol.288 , pp. 259-265
    • Lawrenson, J.G.1    Reid, A.R.2    Allt, G.3
  • 120
    • 0029938236 scopus 로고    scopus 로고
    • Predicting blood-brain transport of drugs: A computational approach
    • Basak, S.C , Gute, B.D. & Drewes, L.R. (1996). Predicting blood-brain transport of drugs: a computational approach. Pharmacological Research 13, 775-778.
    • (1996) Pharmacological Research , vol.13 , pp. 775-778
    • Basak, S.C.1    Gute, B.D.2    Drewes, L.R.3
  • 121
    • 0030462889 scopus 로고    scopus 로고
    • Computation of brain-blood partitioning of organic solutes via free energy calculations
    • Lombardo, F., Blake, J.F, & Curatolo, W.J. (1996) Computation of brain-blood partitioning of organic solutes via free energy calculations Journal of Medical Chemistry 39, 4750-4755.
    • (1996) Journal of Medical Chemistry , vol.39 , pp. 4750-4755
    • Lombardo, F.1    Blake, J.F.2    Curatolo, W.J.3
  • 122
    • 0028108085 scopus 로고
    • Hydrogen bonding. 33. Factors that influence the distribution of solutes between blood and brain
    • Abraham, M.H., Chada, H.S & Mitchell, R.C. (1994). Hydrogen bonding. 33. Factors that influence the distribution of solutes between blood and brain. Journal of Pharmacological Science 83, 1257-1268.
    • (1994) Journal of Pharmacological Science , vol.83 , pp. 1257-1268
    • Abraham, M.H.1    Chada, H.S.2    Mitchell, R.C.3
  • 125
    • 0022454431 scopus 로고
    • Characteristics of the large neutral amino acid transport system of bovine brain microvessel endothelial cell monolayers
    • Audus, K. & Borchardt, R. (1986). Characteristics of the large neutral amino acid transport system of bovine brain microvessel endothelial cell monolayers Journal of Neurochemistry 47, 484-488.
    • (1986) Journal of Neurochemistry , vol.47 , pp. 484-488
    • Audus, K.1    Borchardt, R.2
  • 126
    • 0024956954 scopus 로고
    • In vitro characterization of blood-brain barrier permeability to δ sleep-inducing peptide
    • Raetssi, S & Audus, K. (1989) In vitro characterization of blood-brain barrier permeability to δ sleep-inducing peptide. Journal of Pharmacy and Pharmacology 41, 848-852.
    • (1989) Journal of Pharmacy and Pharmacology , vol.41 , pp. 848-852
    • Raetssi, S.1    Audus, K.2
  • 127
    • 0025232539 scopus 로고
    • Acivicin transport across bovine brain microvessel endothelial cell monolayers: A model of the blood-brain barrier
    • Chastain, J & Borchardt, R. (1990). Acivicin transport across bovine brain microvessel endothelial cell monolayers: a model of the blood-brain barrier Neuroscience Research Communications 6, 51-55.
    • (1990) Neuroscience Research Communications , vol.6 , pp. 51-55
    • Chastain, J.1    Borchardt, R.2
  • 128
    • 0024379547 scopus 로고
    • Transport of vasopressin fragments across the blood-brain barrier, in vitro studies using monolayer cultures of bovine brain endothelial cells
    • van Bree, J., de Boer, A., Verhoef, J., Danhof, M & Brenner, D (1989) Transport of vasopressin fragments across the blood-brain barrier, in vitro studies using monolayer cultures of bovine brain endothelial cells. Journal of Pharmacology and Experimental Therapeutics 249, 901-905
    • (1989) Journal of Pharmacology and Experimental Therapeutics , vol.249 , pp. 901-905
    • Van Bree, J.1    De Boer, A.2    Verhoef, J.3    Danhof, M.4    Brenner, D.5
  • 129
    • 0031543942 scopus 로고    scopus 로고
    • Cellular mechanisms regulating losartan transfer across brain capillary endothelial cells in primary culture
    • Rose, J. & Audus, K. (1997). Cellular mechanisms regulating losartan transfer across brain capillary endothelial cells in primary culture. S.T P Pharmaceutical Sciences 7, 71-77
    • (1997) S.T P Pharmaceutical Sciences , vol.7 , pp. 71-77
    • Rose, J.1    Audus, K.2
  • 130
    • 0030239093 scopus 로고    scopus 로고
    • Human brain microvessel endothelial cell culture as a model system to study vascular factors of ischemic brain
    • Nagy, Z , Vastag, M , Skopal, J . Kolev, K., Macovich, R , Kramer, J., Karadi, I. & Toth, M. (1996) Human brain microvessel endothelial cell culture as a model system to study vascular factors of ischemic brain. Keio Journal of Medicine 45, 200-206.
    • (1996) Keio Journal of Medicine , vol.45 , pp. 200-206
    • Nagy, Z.1    Vastag, M.2    Skopal, J.3    Kolev, K.4    Macovich, R.5    Kramer, J.6    Karadi, I.7    Toth, M.8
  • 131
    • 0030024463 scopus 로고    scopus 로고
    • Effects of barbiturates on hypoxic cultures of brain derived microvascular endothelial cells
    • Fischer, S., Renz, D., Schaper, W & Karliczek, G F. (1996). Effects of barbiturates on hypoxic cultures of brain derived microvascular endothelial cells Brain Research 707, 47-53
    • (1996) Brain Research , vol.707 , pp. 47-53
    • Fischer, S.1    Renz, D.2    Schaper, W.3    Karliczek, G.F.4
  • 133
    • 0030446969 scopus 로고    scopus 로고
    • Vascular endothelial growth factor affects permeability of brain microvessel endothelial cells in vitro
    • Wang, W., Merrill, M.J. & Borchardt, R.T. (1996). Vascular endothelial growth factor affects permeability of brain microvessel endothelial cells in vitro. American Journal of Physiology - Cell Physiology 271, 1973-1980.
    • (1996) American Journal of Physiology - Cell Physiology , vol.271 , pp. 1973-1980
    • Wang, W.1    Merrill, M.J.2    Borchardt, R.T.3
  • 134
    • 0028991313 scopus 로고
    • Peptidyl dipeptidase A-catalyzed metabolism of δ sleep-inducing peptide in bovine brain microvessel endothelial cells: A cell culture model of the blood-brain barrier
    • Augustijns, P., Ka-yun, N., Williams, T. & Borchardt, R. (1995). Peptidyl dipeptidase A-catalyzed metabolism of δ sleep-inducing peptide in bovine brain microvessel endothelial cells: a cell culture model of the blood-brain barrier Biochemical and Biophysical Research Communications 210, 987-994.
    • (1995) Biochemical and Biophysical Research Communications , vol.210 , pp. 987-994
    • Augustijns, P.1    Ka-yun, N.2    Williams, T.3    Borchardt, R.4
  • 137
    • 0023278746 scopus 로고
    • Optimised medium for clonal growth of human microvascular cells with minimal serum
    • Knedler, E.G. & Ham, R.F. (1987). Optimised medium for clonal growth of human microvascular cells with minimal serum. In Vivo 23, 481-489.
    • (1987) In Vivo , vol.23 , pp. 481-489
    • Knedler, E.G.1    Ham, R.F.2
  • 138
    • 0027473740 scopus 로고
    • Biotin uptake and transport across bovine brain microvessel endothelial cell monolayers
    • Shi, F., Bailey, C., Malick, A. & Audus, K. (1993) Biotin uptake and transport across bovine brain microvessel endothelial cell monolayers Pharmacological Research (NY) 10, 282-288.
    • (1993) Pharmacological Research (NY) , vol.10 , pp. 282-288
    • Shi, F.1    Bailey, C.2    Malick, A.3    Audus, K.4


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