In vitro toxicology methods in risk assessment

Alternatives to Laboratory Animals

Volumn 24, Issue 3, 1996, Pages 325-331

  Purchase, Iain F H ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Alternative methods; Hazard assessment; Risk assessment; Toxicity testing; Validation

Indexed keywords

SALMONELLA;

EID: 2842579545     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Balls, M., Blaauboer, B.J., Fentem, J.H., Bruner, L., Combes, R.D., Ekwall, B., Fielder, R.J., Guillouzo, A., Lewis, R.W., Lovell, D.P., Reinhardt, C.A., Repetto, G., Sladowski, D., Spielmann, H. & Zucco, F. (1995). Practical aspects of the validation of toxicity test procedures. The report and recommendations of EVAM workshop 5. ATLA 23, 129-147.
2. Walum, E., Clemedson, C. & Ekwall, B. (1994). Principles for validation of in vitro toxicology test methods. Toxicology in Vitro 8, 807 -812.c
3. Crump, K.S. (1984). A new method for determining allowable daily intake rates. Fundamental and Applied Toxicology 4, 854-871.
4. Pease, W., Vandenberg, J. & Hooper, K. (1991) Comparing alternative approaches to establishing regulatory levels for reproductive toxicants: DBCP as a case study. Environmental Health Perspectives 91, 141-155.
5. Ashby, J., Brady, A., Elcombe, C.R., Elliott, B.M., Ishmael, J., Odum, J., Tugwood, J.D., Kettle, S. & Purchase, I.F.H. (1994). Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis, Human and Experimental Toxicology 13, Suppl. 1, 1-117.
6. Purchace, I.F.H. (1992). Industry's needs for in vitro toxicology: a personal view. In In Vitro Methods in Toxicology (ed. G. Jolies & A. Cordier), pp. 535-542. London: Academic Press.
7. Bondesson, I., Ekwall, B., Hellberg, S., Romert, L., Stenberg, K & Walum, E. (1989). MEIC: a new international project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests. Cell Biology and Toxicology 5, 331-346.