Determination of the starting dose for acute oral toxicity (LD50) testing in the up and down procedure (UDP) from cytotoxicity data

Alternatives to Laboratory Animals

Volumn 27, Issue 6, 1999, Pages 957-966

  Spielmann, Horst ^a   Genschow, Elke ^a   Liebsch, Manfred ^a   Halle, Willi ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Acute oral toxicity; Cell lines; Cytotoxicity; IC50; LD50; RC; Register of Cytotoxicity; UDP; Up and Down Procedure

Indexed keywords

4 AMINOPHENOL; ACETONITRILE; CAFFEINE; COUMARIN; MERCURY CHLORIDE; N,N DIMETHYLFORMAMIDE; NICOTINE; PHENYLTHIOUREA; RESORCINOL;

ACUTE TOXICITY; ARTICLE; CELL LINE; CYTOTOXICITY TEST; LD 50; LETHAL DOSE; PRIORITY JOURNAL; REGISTER; REGRESSION ANALYSIS; TECHNIQUE; TOXICITY TESTING;

ANIMALIA;

EID: 0033396790     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119299902700609     Document Type: Article

References (22)

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