Development of an in vitro test battery for the estimation of acute human systemic toxicity: An outline of the EDIT project

ATLA Alternatives to Laboratory Animals

Volumn 30, Issue 3, 2002, Pages 313-321

  Clemedson, Cecilia ^a   Nordin Andersson, Marika ^a   Bjerregaard, Henning F ^a   Clausen, Joørgen ^a   Forsby, Anna ^a   Gustafsson, Helena ^a   Hansson, Ulrika ^a   Isomaa, Boris ^a   Joørgensen, Carsten ^a   Kolman, Ada ^a   Kotova, Natalia ^a   Krause, Gunter ^a   Kristen, Udo ^a   Kurppa, Kalle ^a   Romert, Lennart ^a   Scheers, Ellen ^a  

^a Expertradet AB   (Sweden)

Author keywords

Acute toxicity testing; Basal cytotoxicity; Biotransformation; Blood brain barrier models; Human toxicity; Kinetics; Neurotoxicity; Quantitative structure activity relationships; Target organ toxicity

Indexed keywords

ACETYLSALICYLIC ACID; AMITRIPTYLINE; AMPHETAMINE; ARSENIC; ATROPINE; COPPER; CYANIDE; DIAZEPAM; DIGOXIN; ETHYLENE GLYCOL; LINDANE; MALATHION; MERCURY; METHANOL; NICOTINE; PARACETAMOL; PARAQUAT; SODIUM CHLORIDE; THALLIUM; VERAPAMIL;

BIOTRANSFORMATION; BLOOD BRAIN BARRIER; CELL LINE; CONFERENCE PAPER; CYTOTOXICITY; DATA BASE; DISTRIBUTION VOLUME; EVALUATION; GASTROINTESTINAL ABSORPTION; HUMAN; HUMAN CELL; KIDNEY CLEARANCE; LABORATORY TEST; LETHALITY; MODEL; NEUROTOXICITY; ORGANIZATION; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SCANDINAVIA; TOXICITY TESTING; TOXICOKINETICS; VALIDATION PROCESS;

EID: 18444406264     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290203000309     Document Type: Conference Paper

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