The acquisition and application of absorption, distribution, metabolism, and excretion (ADME) data in agricultural chemical safety assessments

Critical Reviews in Toxicology

Volumn 36, Issue 1, 2006, Pages 9-35

  Barton, Hugh A ^a   Pastoor, Timothy P ^b   Baetcke, Karl ^a   Chambers, Janice E ^c   Diliberto, Janet ^d   Doerrer, Nancy G ^e   Driver, Jeffrey H ^f   Hastings, Charles E ^g   Iyengar, Seshadri ^h   Krieger, Robert ⁱ   Stahl, Bernhard ^j   Timchalk, Charles ^k  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b SYNGENTA CROP PROTECTION   (United States)

^c MISSISSIPPI STATE UNIVERSITY   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e ILSI HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE   (United States)

^f Infoscientificcom Inc   (United States)

^g BASF CORPORATION   (United States)

^h BAYER CROPSCIENCE AG   (Germany)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j BAYER AG   (Germany)

^k PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

more..

Author keywords

Absorption; ADME; Agricultural Chemicals; Distribution; Excretion; Metabolism; Pharmacokinetics; Tiered Testing

Indexed keywords

AGRICULTURAL CHEMICAL; ATRAZINE; AZINPHOS METHYL; CARBON 14; CHLORPYRIFOS; DIETHYLTOLUAMIDE; DIQUAT; ISOFENPHOS; LINDANE; MALATHION; PARATHION; PERMETHRIN; PESTICIDE; PROPOXUR; PROPYLENE GLYCOL;

ABSORPTION; ANIMAL TESTING REFINEMENT; AREA UNDER THE CURVE; BIOAVAILABILITY; BIOLOGICAL MONITORING; BODY DISTRIBUTION; CROP PROTECTION; DATA ANALYSIS; ENVIRONMENTAL EXPOSURE; EXCRETION; FECES ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; METABOLITE; METHODOLOGY; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; OUTCOMES RESEARCH; QUANTITATIVE ASSAY; RADIOACTIVITY; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; SAFETY; TOXICITY TESTING; TOXICOKINETICS; URINALYSIS;

AGROCHEMICALS; ANIMALS; HUMANS; RISK ASSESSMENT; SAFETY MANAGEMENT;

ANIMALIA;

EID: 33644867772     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.1080/10408440500534362     Document Type: Review

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