Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Shemer, Anat ^a   Grozovski, Jonathan ^a   Tay, Tuan Leng ^b   Tao, Jenhan ^c   Volaski, Alon ^a   Süß, Patrick ^b   Ardura Fabregat, Alberto ^b   Gross Vered, Mor ^a   Kim, Jung Seok ^a   David, Eyal ^a   Chappell Maor, Louise ^a   Thielecke, Lars ^d   Glass, Christopher K ^c   Cornils, Kerstin ^e   Prinz, Marco ^b   Jung, Steffen ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; ENDOTOXIN; FC RECEPTOR; FLUDARABINE; NUCLEAR RECEPTOR NUR77; RNA BINDING PROTEIN; SODIUM GLUCOSE COTRANSPORTER 1; THIOTEPA; TRANSCRIPTOME; TREOSULFAN; LIPOPOLYSACCHARIDE;

ABNORMALITY; BRAIN; CELL; MOLECULAR ANALYSIS; NERVOUS SYSTEM; TOXIN;

ACUTE MYELOID LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CANCER CHEMOTHERAPY; CELL CLONING; CELL EXPANSION; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CHROMATIN; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; FOLLOW UP; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LONGEVITY; MACROPHAGE; MICROGLIA; MOUSE; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; MYELOABLATIVE CONDITIONING; NONHUMAN; OLFACTORY BULB; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PHAGOCYTOSIS; PNEUMONIA; RADIOSENSITIVITY; RESPIRATORY FAILURE; SKIN; STEM CELL TRANSPLANTATION; VIRUS REACTIVATION; WHOLE BODY RADIATION; ANIMAL; BRAIN; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; FEMALE; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MALE; METABOLISM; PROCEDURES; TRANSGENIC MOUSE;

ANIMALS; BRAIN; CELL PROLIFERATION; CHROMATIN; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; TRANSCRIPTOME;

EID: 85058024808     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-07548-5     Document Type: Article

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