Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

Immunity

Volumn 43, Issue 1, 2015, Pages 92-106

  Bruttger, Julia ^a   Karram, Khalad ^a   Wörtge, Simone ^a   Regen, Tommy ^a   Marini, Federico ^a   Hoppmann, Nicola ^a   Klein, Matthias ^a   Blank, Thomas ^b   Yona, Simon ^c   Wolf, Yochai ^c   Mack, Matthias ^d   Pinteaux, Emmanuel ^e   Müller, Werner ^e   Zipp, Frauke ^a   Binder, Harald ^a   Bopp, Tobias ^a   Prinz, Marco ^b   Jung, Steffen ^c   Waisman, Ari ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; NESTIN; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; IL1R1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BONE MARROW CELL; BRAIN REGION; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE STORM; FLOW CYTOMETRY; GENETIC CELL ABLATION; GENETIC PROCEDURES; HEMATOPOIETIC STEM CELL; MACROPHAGE; MICROGLIA; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEADY STATE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; DNA SEQUENCE; GENETICS; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE;

ANIMALS; BASE SEQUENCE; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROGLIA; RECEPTORS, CHEMOKINE; RECEPTORS, INTERLEUKIN-1 TYPE I; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84937738858     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.06.012     Document Type: Article

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