Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

Cell Reports

Volumn 18, Issue 2, 2017, Pages 391-405

  Askew, Katharine ^a   Li, Kaizhen ^b   Olmos Alonso, Adrian ^a   Garcia Moreno, Fernando ^c   Liang, Yajie ^b   Richardson, Philippa ^a   Tipton, Tom ^a   Chapman, Mark A ^a   Riecken, Kristoffer ^d   Beccari, Sol ^e   Sierra, Amanda ^e   Molnár, Zoltán ^c   Cragg, Mark S ^a   Garaschuk, Olga ^b   Perry, V Hugh ^a   Gomez Nicola, Diego ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

BrdU; CSF1R; CX3CR1; Macgreen; RNA seq; self renewal; Vav Bcl2

Indexed keywords

CASPASE 3; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; NESTIN; PROTEIN BCL 2; TRANSCRIPTION FACTOR PU 1;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CELL DENSITY; CELL DIFFERENTIATION; CELL EXPANSION; CELL FUNCTION; CELL INFILTRATION; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CHROMATIN CONDENSATION; CONTROLLED STUDY; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IRF8 GENE; MICROGLIA; MONOCYTE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PU 1 GENE; TURNOVER TIME; UPREGULATION; AGING; ANIMAL; BRAIN; CYTOLOGY; GENE EXPRESSION PROFILING; METABOLISM; PHYSIOLOGY; TIME FACTOR;

AGING; ANIMALS; APOPTOSIS; BRAIN; CELL COUNT; CELL PROLIFERATION; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMANS; MICE; MICROGLIA; MONOCYTES; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS;

EID: 85009165788     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.12.041     Document Type: Article

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