Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Deczkowska, Aleksandra ^a   Matcovitch Natan, Orit ^a   Tsitsou Kampeli, Afroditi ^a   Ben Hamo, Sefi ^a   Dvir Szternfeld, Raz ^a   Spinrad, Amit ^a   Singer, Oded ^a   David, Eyal ^a   Winter, Deborah R ^a   Smith, Lucas K ^b   Kertser, Alexander ^a   Baruch, Kuti ^a   Rosenzweig, Neta ^a   Terem, Anna ^c   Prinz, Marco ^d,e   Villeda, Saul ^b   Citri, Ami ^c   Amit, Ido ^a   Schwartz, Michal ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d UNIVERSITY OF FREIBURG   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CD11B ANTIGEN; CD45 ANTIGEN; INTERFERON; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOCYTE ENHANCER FACTOR 2; RANTES; TUMOR NECROSIS FACTOR;

BRAIN; CELLS AND CELL COMPONENTS; GENE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNE SYSTEM; PROTEIN;

ADULT; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CHOROID PLEXUS; COGNITION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; IN VITRO STUDY; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; RNA SEQUENCE; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; UPREGULATION; ANIMAL; BRAIN; C57BL MOUSE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; MALE; PATHOPHYSIOLOGY;

MUS;

AGING; ANIMALS; BRAIN; HUMANS; INTERFERON-BETA; MALE; MEF2 TRANSCRIPTION FACTORS; MICE; MICE, INBRED C57BL; MICROGLIA;

EID: 85030102941     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00769-0     Document Type: Article

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