메뉴 건너뛰기




Volumn 9, Issue 5, 2018, Pages 725-742

The application of in vitro human intestinal models on the screening and development of pre-And probiotics

Author keywords

Fermentation; Gut microbiota; Healthy gut; Screening

Indexed keywords

MUCIN; POLYMER; PREBIOTIC AGENT; PROBIOTIC AGENT;

EID: 85054549063     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2017.0164     Document Type: Article
Times cited : (86)

References (117)
  • 1
    • 84913534827 scopus 로고    scopus 로고
    • In vitro characterization of the impact of different substrates on metabolite production, energy extraction and composition of gut microbiota from lean and obese subjects
    • Aguirre, M., Jonkers, D.M., Troost, F.J., Roeselers, G. and Venema, K., 2014a. In vitro characterization of the impact of different substrates on metabolite production, energy extraction and composition of gut microbiota from lean and obese subjects. PLoS ONE 9: 113864.
    • (2014) PLoS ONE , vol.9 , pp. 113864
    • Aguirre, M.1    Jonkers, D.M.2    Troost, F.J.3    Roeselers, G.4    Venema, K.5
  • 2
    • 84907556347 scopus 로고    scopus 로고
    • To pool or not to pool? Impact of the use of individual and pooled fecal samples for in vitro fermentation studies
    • Aguirre, M., Ramiro-Garcia, J., Koenen, M.E. and Venema, K., 2014b. To pool or not to pool? Impact of the use of individual and pooled fecal samples for in vitro fermentation studies. Journal of Microbiological Methods 107: 1-7.
    • (2014) Journal of Microbiological Methods , vol.107 , pp. 1-7
    • Aguirre, M.1    Ramiro-Garcia, J.2    Koenen, M.E.3    Venema, K.4
  • 3
    • 85013188092 scopus 로고    scopus 로고
    • Challenges in simulating the human gut for understanding the role of the microbiota in obesity
    • Aguirre, M. and Venema, K., 2017. Challenges in simulating the human gut for understanding the role of the microbiota in obesity. Beneficial Microbes 8: 31-53.
    • (2017) Beneficial Microbes , vol.8 , pp. 31-53
    • Aguirre, M.1    Venema, K.2
  • 9
    • 77956055574 scopus 로고    scopus 로고
    • Bacterial, SCFA and gas profiles of a range of food ingredients following in vitro fermentation by human colonic microbiota
    • Beards, E., Tuohy, K. and Gibson, G., 2010. Bacterial, SCFA and gas profiles of a range of food ingredients following in vitro fermentation by human colonic microbiota. Anaerobe 16: 420-425.
    • (2010) Anaerobe , vol.16 , pp. 420-425
    • Beards, E.1    Tuohy, K.2    Gibson, G.3
  • 14
    • 84992451544 scopus 로고    scopus 로고
    • Health benefits of fibre, prebiotics and Probiotics: A review of intestinal health and related health claims
    • Carlson, J. and Slavin, J., 2016. Health benefits of fibre, prebiotics and probiotics: A review of intestinal health and related health claims. Quality Assurance and Safety of Crops & Foods 8: 539-553.
    • (2016) Quality Assurance and Safety of Crops & Foods , vol.8 , pp. 539-553
    • Carlson, J.1    Slavin, J.2
  • 15
    • 84866009079 scopus 로고    scopus 로고
    • Influence of encapsulated probiotics combined with pressurized longan juice on colon microflora and their metabolic activities on the exposure to simulated dynamic gastrointestinal tract
    • Chaikham, P., Apichartsrangkoon, A., Jirarattanarangsri, W. and Van de Wiele, T., 2012. Influence of encapsulated probiotics combined with pressurized longan juice on colon microflora and their metabolic activities on the exposure to simulated dynamic gastrointestinal tract. Food Research International 49: 133-142.
    • (2012) Food Research International , vol.49 , pp. 133-142
    • Chaikham, P.1    Apichartsrangkoon, A.2    Jirarattanarangsri, W.3    Van De Wiele, T.4
  • 17
    • 33644932943 scopus 로고    scopus 로고
    • Studies on the effect of system retention time on bacterial populations colonizing a three-stage continuous culture model of the human large gut using FISH techniques
    • Child, M.W., Kennedy, A., Walker, A.W., Bahrami, B., MacFarlane, S. and MacFarlane, G.T., 2006. Studies on the effect of system retention time on bacterial populations colonizing a three-stage continuous culture model of the human large gut using FISH techniques. FEMS Microbiology Ecology 55: 299-310.
    • (2006) FEMS Microbiology Ecology , vol.55 , pp. 299-310
    • Child, M.W.1    Kennedy, A.2    Walker, A.W.3    Bahrami, B.4    MacFarlane, S.5    MacFarlane, G.T.6
  • 19
    • 4444305247 scopus 로고    scopus 로고
    • Immobilization of infant fecal microbiota and utilization in an in vitro colonic fermentation model
    • Cinquin, C., Le Blay, G., Fliss, I. and Lacroix, C., 2004. Immobilization of infant fecal microbiota and utilization in an in vitro colonic fermentation model. Microbial Ecology 48: 128-138.
    • (2004) Microbial Ecology , vol.48 , pp. 128-138
    • Cinquin, C.1    Le Blay, G.2    Fliss, I.3    Lacroix, C.4
  • 20
    • 33745789622 scopus 로고    scopus 로고
    • Comparative effects of exopolysaccharides from lactic acid bacteria and fructo-oligosaccharides on infant gut microbiota tested in an in vitro colonic model with immobilized cells
    • Cinquin, C., Le Blay, G., Fliss, I. and Lacroix, C., 2006. Comparative effects of exopolysaccharides from lactic acid bacteria and fructo-oligosaccharides on infant gut microbiota tested in an in vitro colonic model with immobilized cells. FEMS Microbiology Ecology 57: 226-238.
    • (2006) FEMS Microbiology Ecology , vol.57 , pp. 226-238
    • Cinquin, C.1    Le Blay, G.2    Fliss, I.3    Lacroix, C.4
  • 21
    • 84864333229 scopus 로고    scopus 로고
    • Effect of prebiotics on biomarkers of colorectal cancer in humans: A systematic review
    • Clark, M.J., Robien, K. and Slavin, J.L., 2012. Effect of prebiotics on biomarkers of colorectal cancer in humans: A systematic review. Nutrition Reviews 70: 436-443.
    • (2012) Nutrition Reviews , vol.70 , pp. 436-443
    • Clark, M.J.1    Robien, K.2    Slavin, J.L.3
  • 22
    • 0028968536 scopus 로고
    • Human relevance of animal carcinogenicity studies
    • Cohen, S.M., 1995. Human relevance of animal carcinogenicity studies. Regulatory Toxicology and Pharmacology 21: 75-80.
    • (1995) Regulatory Toxicology and Pharmacology , vol.21 , pp. 75-80
    • Cohen, S.M.1
  • 23
    • 84961327480 scopus 로고    scopus 로고
    • Effects of orange juice formulation on prebiotic functionality using an in vitro colonic model system
    • Costabile, A., Walton, G.E., Tzortzis, G., Vulevic, J., Charalampopoulos, D. and Gibson, G.R., 2015. Effects of orange juice formulation on prebiotic functionality using an in vitro colonic model system. PLoS ONE 10: 0121955.
    • (2015) PLoS ONE , vol.10 , pp. 0121955
    • Costabile, A.1    Walton, G.E.2    Tzortzis, G.3    Vulevic, J.4    Charalampopoulos, D.5    Gibson, G.R.6
  • 24
    • 0025855242 scopus 로고
    • The control and consequences of bacterial fermentation in the human colon
    • Cummings, J.H. and MacFarlane, G.T., 1991. The control and consequences of bacterial fermentation in the human colon. Journal of Applied Bacteriology 70: 443-459.
    • (1991) Journal of Applied Bacteriology , vol.70 , pp. 443-459
    • Cummings, J.H.1    MacFarlane, G.T.2
  • 25
    • 84953426144 scopus 로고    scopus 로고
    • Arabinogalactan and fructooligosaccharides improve the gut barrier function in distinct areas of the colon in the simulator of the human intestinal microbial ecosystem
    • Daguet, D., Pinheiro, I., Verhelst, A., Possemiers, S. and Marzorati, M., 2016. Arabinogalactan and fructooligosaccharides improve the gut barrier function in distinct areas of the colon in the Simulator of the Human Intestinal Microbial Ecosystem. Journal of Functional Foods 20: 369-379.
    • (2016) Journal of Functional Foods , vol.20 , pp. 369-379
    • Daguet, D.1    Pinheiro, I.2    Verhelst, A.3    Possemiers, S.4    Marzorati, M.5
  • 29
    • 84870943246 scopus 로고    scopus 로고
    • Low iron availability in continuous in vitro colonic fermentations induces strong dysbiosis of the child gut microbial consortium and a decrease in main metabolites
    • Dostal, A., Fehlbaum, S., Chassard, C., Zimmermann, M.B. and Lacroix, C., 2012. Low iron availability in continuous in vitro colonic fermentations induces strong dysbiosis of the child gut microbial consortium and a decrease in main metabolites. FEMS Microbiology Ecology 83: 161-175.
    • (2012) FEMS Microbiology Ecology , vol.83 , pp. 161-175
    • Dostal, A.1    Fehlbaum, S.2    Chassard, C.3    Zimmermann, M.B.4    Lacroix, C.5
  • 30
    • 68249110221 scopus 로고    scopus 로고
    • The role of pH in determining the species composition of the human colonic microbiota
    • Duncan, S.H., Louis, P., Thomson, J.M. and Flint, H.J., 2009. The role of pH in determining the species composition of the human colonic microbiota. Environmental Microbiology 11: 2112-2122.
    • (2009) Environmental Microbiology , vol.11 , pp. 2112-2122
    • Duncan, S.H.1    Louis, P.2    Thomson, J.M.3    Flint, H.J.4
  • 33
    • 84955496277 scopus 로고    scopus 로고
    • Design and investigation of polyferms in vitro continuous fermentation models inoculated with immobilized fecal microbiota mimicking the elderly colon
    • Fehlbaum, S., Chassard, C., Haug, M.C., Fourmestraux, C., Derrien, M. and Lacroix, C., 2015. Design and investigation of polyferms in vitro continuous fermentation models inoculated with immobilized fecal microbiota mimicking the elderly colon. PLoS ONE 10: 0142793.
    • (2015) PLoS ONE , vol.10 , pp. 0142793
    • Fehlbaum, S.1    Chassard, C.2    Haug, M.C.3    Fourmestraux, C.4    Derrien, M.5    Lacroix, C.6
  • 34
    • 0141757353 scopus 로고    scopus 로고
    • Mixed culture fermentation studies on the effects of synbiotics on the human intestinal pathogens campylobacter jejuni and Escherichia coli
    • Fooks, L.J. and Gibson, G.R., 2003. Mixed culture fermentation studies on the effects of synbiotics on the human intestinal pathogens Campylobacter jejuni and Escherichia coli. Anaerobe 9: 231-242.
    • (2003) Anaerobe , vol.9 , pp. 231-242
    • Fooks, L.J.1    Gibson, G.R.2
  • 36
    • 0024117598 scopus 로고
    • Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria
    • Gibson, G.R., Cummings, J.H. and MacFarlane, G.T., 1988. Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria. Applied and Environmental Microbiology 54: 2750-2755.
    • (1988) Applied and Environmental Microbiology , vol.54 , pp. 2750-2755
    • Gibson, G.R.1    Cummings, J.H.2    MacFarlane, G.T.3
  • 38
    • 0029013322 scopus 로고
    • Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics
    • Gibson, G.R. and Roberfroid, M.B., 1995. Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics. Journal of Nutrition 125: 1401-1412.
    • (1995) Journal of Nutrition , vol.125 , pp. 1401-1412
    • Gibson, G.R.1    Roberfroid, M.B.2
  • 39
    • 84940764361 scopus 로고    scopus 로고
    • Potential role of the intestinal microbiota in programming health and disease
    • Goulet, O., 2015. Potential role of the intestinal microbiota in programming health and disease. Nutrition Reviews 73, Suppl. 1: 32-40.
    • (2015) Nutrition Reviews , vol.73 , pp. 32-40
    • Goulet, O.1
  • 40
    • 85044247408 scopus 로고    scopus 로고
    • In vitro fermentation of B-GOS: Impact on faecal bacterial populations and metabolic activity in autistic and non-Autistic children
    • Grimaldi, R., Cela, D., Swann, J.R., Vulevic, J., Gibson, G.R., Tzortzis, G. and Costabile, A., 2017. In vitro fermentation of B-GOS: Impact on faecal bacterial populations and metabolic activity in autistic and non-Autistic children. FEMS Microbiology Ecology 93(2): 233.
    • (2017) FEMS Microbiology, Ecology , vol.93 , Issue.2 , pp. 233
    • Grimaldi, R.1    Cela, D.2    Swann, J.R.3    Vulevic, J.4    Gibson, G.R.5    Tzortzis, G.6    Costabile, A.7
  • 42
    • 84901361574 scopus 로고    scopus 로고
    • Germ-free mice as a model to study effect of gut microbiota on host physiology
    • Grover, M. and Kashyap, P.C., 2014. Germ-free mice as a model to study effect of gut microbiota on host physiology. Neurogastroenterology and Motility 26: 745-748.
    • (2014) Neurogastroenterology and Motility , vol.26 , pp. 745-748
    • Grover, M.1    Kashyap, P.C.2
  • 43
    • 33644549184 scopus 로고    scopus 로고
    • Enteric flora in health and disease
    • Guarner, F., 2006. Enteric flora in health and disease. Digestion 73, Suppl. 1: 5-12.
    • (2006) Digestion , vol.73 , pp. 5-12
    • Guarner, F.1
  • 44
    • 85021776357 scopus 로고    scopus 로고
    • Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function
    • Henry, O.Y.F., Villenave, R., Cronce, M.J., Leineweber, W.D., Benz, M.A. and Ingber, D.E., 2017. Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function. Lab on a Chip 17: 2264-2271.
    • (2017) Lab on a Chip , vol.17 , pp. 2264-2271
    • Henry, O.Y.F.1    Villenave, R.2    Cronce, M.J.3    Leineweber, W.D.4    Benz, M.A.5    Ingber, D.E.6
  • 49
    • 84930965812 scopus 로고    scopus 로고
    • Prebiotics modulate the effects of antibiotics on gut microbial diversity and functioning in vitro
    • Johnson, L.P., Walton, G.E., Psichas, A., Frost, G.S., Gibson, G.R. and Barraclough, T.G., 2015. Prebiotics modulate the effects of antibiotics on gut microbial diversity and functioning in vitro. Nutrients 7: 4480-4497.
    • (2015) Nutrients , vol.7 , pp. 4480-4497
    • Johnson, L.P.1    Walton, G.E.2    Psichas, A.3    Frost, G.S.4    Gibson, G.R.5    Barraclough, T.G.6
  • 50
    • 84862207235 scopus 로고    scopus 로고
    • Human gut-on-A-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
    • Kim, H.J., Huh, D., Hamilton, G. and Ingber, D.E., 2012. Human gut-on-A-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab on a Chip 12: 2165-2174.
    • (2012) Lab on a Chip , vol.12 , pp. 2165-2174
    • Kim, H.J.1    Huh, D.2    Hamilton, G.3    Ingber, D.E.4
  • 51
    • 84876237691 scopus 로고    scopus 로고
    • Exploring host-microbiota interactions in animal models and humans
    • Kostic, A.D., Howitt, M.R. and Garrett, W.S., 2013. Exploring host-microbiota interactions in animal models and humans. Genes and Development 27: 701-718.
    • (2013) Genes and Development , vol.27 , pp. 701-718
    • Kostic, A.D.1    Howitt, M.R.2    Garrett, W.S.3
  • 53
    • 84920261684 scopus 로고    scopus 로고
    • Integrated multi-scale strategies to investigate nutritional compounds and their effect on the gut microbiota
    • Lacroix, C., De Wouters, T. and Chassard, C., 2015. Integrated multi-scale strategies to investigate nutritional compounds and their effect on the gut microbiota. Current Opinion in Biotechnology 32: 149-155.
    • (2015) Current Opinion in Biotechnology , vol.32 , pp. 149-155
    • Lacroix, C.1    De Wouters, T.2    Chassard, C.3
  • 55
    • 77449092401 scopus 로고    scopus 로고
    • Set up of a new in vitro model to study dietary fructans fermentation in formula-fed babies
    • Le Blay, G., Chassard, C., Baltzer, S. and Lacroix, C., 2010. Set up of a new in vitro model to study dietary fructans fermentation in formula-fed babies. British Journal of Nutrition 103: 403-411.
    • (2010) British Journal of Nutrition , vol.103 , pp. 403-411
    • Le Blay, G.1    Chassard, C.2    Baltzer, S.3    Lacroix, C.4
  • 56
    • 84898604796 scopus 로고    scopus 로고
    • An in vitro study of the effect of probiotics, prebiotics and synbiotics on the elderly faecal microbiota
    • Likotrafiti, E., Tuohy, K.M., Gibson, G.R. and Rastall, R.A., 2014. An in vitro study of the effect of probiotics, prebiotics and synbiotics on the elderly faecal microbiota. Anaerobe 27: 50-55.
    • (2014) Anaerobe , vol.27 , pp. 50-55
    • Likotrafiti, E.1    Tuohy, K.M.2    Gibson, G.R.3    Rastall, R.A.4
  • 57
    • 84990955020 scopus 로고    scopus 로고
    • An in vitro approach to study effects of prebiotics and probiotics on the faecal microbiota and selected immune parameters relevant to the elderly
    • Liu, Y., Gibson, G.R. and Walton, G.E., 2016. An in vitro approach to study effects of prebiotics and probiotics on the faecal microbiota and selected immune parameters relevant to the elderly. PLoS ONE 11: 0162604.
    • (2016) PLoS ONE , vol.11 , pp. 0162604
    • Liu, Y.1    Gibson, G.R.2    Walton, G.E.3
  • 58
    • 84863544278 scopus 로고    scopus 로고
    • Galacto-oligosaccharides have prebiotic activity in a dynamic in vitro colon model using a (13)C-labeling, technique
    • Maathuis, A.J., Van den Heuvel, E.G., Schoterman, M.H. and Venema, K., 2012. Galacto-oligosaccharides have prebiotic activity in a dynamic in vitro colon model using a (13)C-labeling technique. Journal of Nutrition 142: 1205-1212.
    • (2012) Journal of Nutrition , vol.142 , pp. 1205-1212
    • Maathuis, A.J.1    Van Den Heuvel, E.G.2    Schoterman, M.H.3    Venema, K.4
  • 59
    • 0024445045 scopus 로고
    • Influence of retention time on degradation of pancreatic enzymes by human colonic bacteria grown in a 3-stage continuous culture, system
    • MacFarlane, G.T., Cummings, J.H., MacFarlane, S. and Gibson, G.R., 1989. Influence of retention time on degradation of pancreatic enzymes by human colonic bacteria grown in a 3-stage continuous culture system. Journal of Applied Bacteriology 67: 520-527.
    • (1989) Journal of Applied Bacteriology , vol.67 , pp. 520-527
    • MacFarlane, G.T.1    Cummings, J.H.2    MacFarlane, S.3    Gibson, G.R.4
  • 60
    • 0026586542 scopus 로고
    • Comparison of fermentation reactions in different regions of the human colon
    • MacFarlane, G.T., Gibson, G.R. and Cummings, J.H., 1992. Comparison of fermentation reactions in different regions of the human colon. Journal of Applied Bacteriology 72: 57-64.
    • (1992) Journal of Applied Bacteriology , vol.72 , pp. 57-64
    • MacFarlane, G.T.1    Gibson, G.R.2    Cummings, J.H.3
  • 61
    • 34247159880 scopus 로고    scopus 로고
    • Models for intestinal fermentation: Association between food components, delivery systems, bioavailability and functional interactions in the gut
    • MacFarlane, G.T. and MacFarlane, S., 2007. Models for intestinal fermentation: Association between food components, delivery systems, bioavailability and functional interactions in the gut. Current Opinion in Biotechnology 18: 156-162.
    • (2007) Current Opinion in Biotechnology , vol.18 , pp. 156-162
    • MacFarlane, G.T.1    MacFarlane, S.2
  • 62
    • 0031944894 scopus 로고    scopus 로고
    • Validation of a three-stage compound continuous culture system for investigating the effect of retention time on the ecology and metabolism, of bacteria in the human colon
    • MacFarlane, G.T., MacFarlane, S. and Gibson, G.R., 1998. Validation of a three-stage compound continuous culture system for investigating the effect of retention time on the ecology and metabolism of bacteria in the human colon. Microbial Ecology 35: 180-187.
    • (1998) Microbial Ecology , vol.35 , pp. 180-187
    • MacFarlane, G.T.1    MacFarlane, S.2    Gibson, G.R.3
  • 63
    • 31944440308 scopus 로고    scopus 로고
    • Colonization of mucin by human intestinal bacteria and establishment of biofilm communities in a two-stage continuous culture system
    • MacFarlane, S., Woodmansey, E.J. and MacFarlane, G.T., 2005. Colonization of mucin by human intestinal bacteria and establishment of biofilm communities in a two-stage continuous culture system. Applied and Environmental Microbiology 71: 7483- 7492.
    • (2005) Applied and Environmental Microbiology , vol.71 , pp. 7483-7492
    • MacFarlane, S.1    Woodmansey, E.J.2    MacFarlane, G.T.3
  • 64
    • 84903228295 scopus 로고    scopus 로고
    • In vitro methods to model the gastrointestinal tract
    • Ouwehand, A.C. and Vaughan, E.E. (eds.), Taylor and Francis, New York, NY, USA
    • Mäkivuokko, H. and Nurminen, P., 2006. In vitro methods to model the gastrointestinal tract. In: Ouwehand, A.C. and Vaughan, E.E. (eds.) Gastrointestinal microbiology. Taylor and Francis, New York, NY, USA, pp. 237-252.
    • (2006) Gastrointestinal Microbiology , pp. 237-252
    • Mäkivuokko, H.1    Nurminen, P.2
  • 66
    • 84937557545 scopus 로고    scopus 로고
    • Addition of acacia gum to a FOS/inulin blend improves its fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)
    • Marzorati, M., Qin, B., Hildebrand, F., Klosterbuer, A., Roughead, Z., Roessle, C., Rochat, F., Raes, J. and Possemiers, S., 2015. Addition of acacia gum to a FOS/inulin blend improves its fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). Journal of Functional Foods 16: 211-222.
    • (2015) Journal of Functional Foods , vol.16 , pp. 211-222
    • Marzorati, M.1    Qin, B.2    Hildebrand, F.3    Klosterbuer, A.4    Roughead, Z.5    Roessle, C.6    Rochat, F.7    Raes, J.8    Possemiers, S.9
  • 73
    • 0028154701 scopus 로고
    • Validation of the simulator of the human intestinal microbial ecosystem (SHIME) reactor using microorganism-Associated activities
    • Molly, K., Vande Woestyne, M., De Smet, I. and Verstraete, W., 1994. Validation of the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) reactor using microorganism-Associated activities. Microbial Ecology in Health and Disease 7: 191-200.
    • (1994) Microbial Ecology in Health and Disease , vol.7 , pp. 191-200
    • Molly, K.1    Vande Woestyne, M.2    De Smet, I.3    Verstraete, W.4
  • 75
    • 0036824184 scopus 로고    scopus 로고
    • Effect of pH and dose on the growth of gut bacteria on prebiotic carbohydrates in vitro
    • Palframan, R.J., Gibson, G.R. and Rastall, R.A., 2002. Effect of pH and dose on the growth of gut bacteria on prebiotic carbohydrates in vitro. Anaerobe 8: 287-292.
    • (2002) Anaerobe 8 , pp. 287-292
    • Palframan, R.J.1    Gibson, G.R.2    Rastall, R.A.3
  • 76
    • 84859322825 scopus 로고    scopus 로고
    • The metabolic activity of gut microbiota in obese children is increased compared with normal-weight children and exhibits more exhaustive substrate utilization
    • Payne, A.N., Chassard, C., Zimmermann, M., Muller, P., Stinca, S. and Lacroix, C., 2011. The metabolic activity of gut microbiota in obese children is increased compared with normal-weight children and exhibits more exhaustive substrate utilization. Nutrition and Diabetes 1: 12.
    • (2011) Nutrition and Diabetes , vol.1 , pp. 12
    • Payne, A.N.1    Chassard, C.2    Zimmermann, M.3    Muller, P.4    Stinca, S.5    Lacroix, C.6
  • 77
    • 84355163054 scopus 로고    scopus 로고
    • Advances and perspectives in in vitro human gut fermentation modeling
    • Payne, A.N., Zihler, A., Chassard, C. and Lacroix, C., 2012. Advances and perspectives in in vitro human gut fermentation modeling. Trends in Biotechnology 30: 17-25.
    • (2012) Trends in Biotechnology , vol.30 , pp. 17-25
    • Payne, A.N.1    Zihler, A.2    Chassard, C.3    Lacroix, C.4
  • 78
    • 85029292664 scopus 로고    scopus 로고
    • Lactate-utilizing community is associated with gut microbiota dysbiosis in colicky infants
    • Pham, V.T., Lacroix, C., Braegger, C.P. and Chassard, C., 2017. Lactate-utilizing community is associated with gut microbiota dysbiosis in colicky infants. Scientific Reports 7: 11176.
    • (2017) Scientific Reports , vol.7 , pp. 11176
    • Pham, V.T.1    Lacroix, C.2    Braegger, C.P.3    Chassard, C.4
  • 80
    • 0036356115 scopus 로고    scopus 로고
    • Investigating the prebiotic and gas-generating effects of selected carbohydrates on the human colonic microflora
    • Probert, H.M. and Gibson, G.R., 2002. Investigating the prebiotic and gas-generating effects of selected carbohydrates on the human colonic microflora. Letters in Applied Microbiology 35: 473-480.
    • (2002) Letters in Applied Microbiology , vol.35 , pp. 473-480
    • Probert, H.M.1    Gibson, G.R.2
  • 82
    • 84858837801 scopus 로고    scopus 로고
    • Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine
    • Rehman, A., Heinsen, F.A., Koenen, M.E., Venema, K., Knecht, H., Hellmig, S., Schreiber, S. and Ott, S.J., 2012. Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine. BMC Microbiology 12: 47.
    • (2012) BMC Microbiology , vol.12 , pp. 47
    • Rehman, A.1    Heinsen, F.A.2    Koenen, M.E.3    Venema, K.4    Knecht, H.5    Hellmig, S.6    Schreiber, S.7    Ott, S.J.8
  • 83
    • 84897889912 scopus 로고    scopus 로고
    • Effect of the novel polysaccharide poly glycoplex(R) on short-chain fatty acid production in a computer-controlled in, vitro model of the human large intestine
    • Reimer, R.A., Maathuis, A.J., Venema, K., Lyon, M.R., Gahler, R.J. and Wood, S., 2014. Effect of the novel polysaccharide PolyGlycopleX(R) on short-chain fatty acid production in a computer-controlled in vitro model of the human large intestine. Nutrients 6: 1115-1127.
    • (2014) Nutrients , vol.6 , pp. 1115-1127
    • Reimer, R.A.1    Maathuis, A.J.2    Venema, K.3    Lyon, M.R.4    Gahler, R.J.5    Wood, S.6
  • 84
    • 84903191942 scopus 로고    scopus 로고
    • Epidemic Clostridium difficile strains demonstrate increased competitive fitness compared to nonepidemic isolates
    • Robinson, C.D., Auchtung, J.M., Collins, J. and Britton, R.A., 2014. Epidemic Clostridium difficile strains demonstrate increased competitive fitness compared to nonepidemic isolates. Infection and Immunity 82: 2815-2825.
    • (2014) Infection and Immunity , vol.82 , pp. 2815-2825
    • Robinson, C.D.1    Auchtung, J.M.2    Collins, J.3    Britton, R.A.4
  • 86
    • 0034776170 scopus 로고    scopus 로고
    • A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides
    • Rycroft, C.E., Jones, M.R., Gibson, G.R. and Rastall, R.A., 2001a. A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides. Journal of Applied Microbiology 91: 878-887.
    • (2001) Journal of Applied Microbiology , vol.91 , pp. 878-887
    • Rycroft, C.E.1    Jones, M.R.2    Gibson, G.R.3    Rastall, R.A.4
  • 89
    • 70349782022 scopus 로고    scopus 로고
    • Exopolysaccharides produced by Bifidobacterium longum IPLA E44 and Bifidobacterium animalis subsp. Lactis IPLA R1 modify the composition and metabolic activity of human faecal microbiota in pH-controlled batch cultures
    • Salazar, N., Ruas-Madiedo, P., Kolida, S., Collins, M., Rastall, R., Gibson, G. and De Los Reyes-Gavilan, C.G., 2009. Exopolysaccharides produced by Bifidobacterium longum IPLA E44 and Bifidobacterium animalis subsp. lactis IPLA R1 modify the composition and metabolic activity of human faecal microbiota in pH-controlled batch cultures. International Journal of Food Microbiology 135: 260-267.
    • (2009) International Journal of Food Microbiology , vol.135 , pp. 260-267
    • Salazar, N.1    Ruas-Madiedo, P.2    Kolida, S.3    Collins, M.4    Rastall, R.5    Gibson, G.6    De Los Reyes-Gavilan, C.G.7
  • 91
    • 84922017600 scopus 로고    scopus 로고
    • Potential of novel dextran oligosaccharides as prebiotics for obesity management through in vitro experimentation
    • Sarbini, S.R., Kolida, S., Deaville, E.R., Gibson, G.R. and Rastall, R.A., 2014. Potential of novel dextran oligosaccharides as prebiotics for obesity management through in vitro experimentation. British Journal of Nutrition 112: 1303-1314.
    • (2014) British Journal, of Nutrition , vol.112 , pp. 1303-1314
    • Sarbini, S.R.1    Kolida, S.2    Deaville, E.R.3    Gibson, G.R.4    Rastall, R.A.5
  • 93
    • 55949096164 scopus 로고    scopus 로고
    • In vitro effects of selected synbiotics on the human faecal microbiota composition
    • Saulnier, D.M., Gibson, G.R. and Kolida, S., 2008. In vitro effects of selected synbiotics on the human faecal microbiota composition. FEMS Microbiology Ecology 66: 516-527.
    • (2008) FEMS Microbiology Ecology , vol.66 , pp. 516-527
    • Saulnier, D.M.1    Gibson, G.R.2    Kolida, S.3
  • 95
    • 84988864262 scopus 로고    scopus 로고
    • Revised estimates for the number of human and bacteria cells, in the body
    • Sender, R., Fuchs, S. and Milo, R., 2016. Revised estimates for the number of human and bacteria cells in the body. PLoS Biology 14: 1002533.
    • (2016) PLoS Biology , vol.14 , pp. 1002533
    • Sender, R.1    Fuchs, S.2    Milo, R.3
  • 97
    • 84880448823 scopus 로고    scopus 로고
    • Arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the simulator of the human intestinal microbial ecosystem (SHIME (R))
    • Terpend, K., Possemiers, S., Daguet, D. and Marzorati, M., 2013. Arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME (R)). Environmental Microbiology Reports 5: 595-603.
    • (2013) Environmental Microbiology Reports , vol.5 , pp. 595-603
    • Terpend, K.1    Possemiers, S.2    Daguet, D.3    Marzorati, M.4
  • 100
    • 1642320639 scopus 로고    scopus 로고
    • In vitro evaluation of the fermentation properties of galactooligosaccharides synthesised by alpha-galactosidase from, Lactobacillus reuteri
    • Tzortzis, G., Goulas, A.K., Baillon, M.L., Gibson, G.R. and Rastall, R.A., 2004. In vitro evaluation of the fermentation properties of galactooligosaccharides synthesised by alpha-galactosidase from Lactobacillus reuteri. Applied Microbiology and Biotechnology 64: 106-111.
    • (2004) Applied Microbiology and Biotechnology , vol.64 , pp. 106-111
    • Tzortzis, G.1    Goulas, A.K.2    Baillon, M.L.3    Gibson, G.R.4    Rastall, R.A.5
  • 102
    • 84945152395 scopus 로고    scopus 로고
    • The Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)
    • Verhoeckx, K. Cotter, P. López-Expósito, I. Kleiveland, C. Lea, T. Mackie, A. Requena, T. Swiatecka, D. and Wichers, H. (eds.), Springer, New York, NY, USA
    • Van de Wiele, T., Van den Abbeele, P., Ossieur, W., Possemiers, S. and Marzorati, M., 2015. The Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). In: Verhoeckx, K., Cotter, P., López-Expósito, I., Kleiveland, C., Lea, T., Mackie, A., Requena, T., Swiatecka, D. and Wichers, H. (eds.) The impact of food bio-Actives on gut health. Springer, New York, NY, USA, pp. 305-317.
    • (2015) The Impact of Food Bio-Actives on Gut Health , pp. 305-317
    • Van De Wiele, T.1    Van Den Abbeele, P.2    Ossieur, W.3    Possemiers, S.4    Marzorati, M.5
  • 105
    • 85041791964 scopus 로고    scopus 로고
    • Arabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a mucosa-comprising gut model
    • Van den Abbeele, P., Marzorati, M., Derde, M., De Weirdt, R., Joan, V., Possemiers, S. and Van de Wiele, T., 2016. Arabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a mucosa-comprising gut model. NPJ Biofilms and Microbiomes 2: 16016.
    • (2016) NPJ Biofilms and Microbiomes , vol.2 , pp. 16016
    • Van Den Abbeele, P.1    Marzorati, M.2    Derde, M.3    De Weirdt, R.4    Joan, V.5    Possemiers, S.6    Van De Wiele, T.7
  • 107
    • 0345257151 scopus 로고    scopus 로고
    • The effect of various inulins and clostridium difficile on the metabolic activity of the human colonic microbiota in vitro
    • Van Nuenen, M.H.M.C., Meyer, P.D. and Venema, K., 2003. The effect of various inulins and Clostridium difficile on the metabolic activity of the human colonic microbiota in vitro. Microbial Ecology in Health and Disease 15: 137-144.
    • (2003) Microbial Ecology, in Health and Disease , vol.15 , pp. 137-144
    • Van Nuenen, M.H.M.C.1    Meyer, P.D.2    Venema, K.3
  • 109
    • 0344233202 scopus 로고    scopus 로고
    • The effect of lactulose on the composition of the intestinal microbiota and short-chain fatty acid production in human volunteers and a computer-controlled model of the proximal large intestine
    • Venema, K., Van Nuenen, M.H.M.C., Van den Heuvel, E.G., Pool, W. and Van der Vossen, J.M.B.M., 2003. The effect of lactulose on the composition of the intestinal microbiota and short-chain fatty acid production in human volunteers and a computer-controlled model of the proximal large intestine. Microbial Ecology in Health and Disease 15: 97-105.
    • (2003) Microbial Ecology in Health and Disease , vol.15 , pp. 97-105
    • Venema, K.1    Van Nuenen, M.H.M.C.2    Van Den Heuvel, E.G.3    Pool, W.4    Van Der Vossen, J.M.B.M.5
  • 110
    • 22144439446 scopus 로고    scopus 로고
    • PH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon
    • Walker, A.W., Duncan, S.H., McWilliam Leitch, E.C., Child, M.W. and Flint, H.J., 2005. pH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon. Applied and Environmental Microbiology 71: 3692-3700.
    • (2005) Applied and Environmental Microbiology , vol.71 , pp. 3692-3700
    • Walker, A.W.1    Duncan, S.H.2    McWilliam Leitch, E.C.3    Child, M.W.4    Flint, H.J.5
  • 111
    • 0027448996 scopus 로고
    • Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine
    • Wang, X. and Gibson, G.R., 1993. Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine. Journal of Applied Bacteriology 75: 373-380.
    • (1993) Journal of Applied Bacteriology , vol.75 , pp. 373-380
    • Wang, X.1    Gibson, G.R.2
  • 112
    • 84995610979 scopus 로고    scopus 로고
    • Necrotizing enterocolitis and preterm infant gut bacteria
    • Warner, B.B. and Tarr, P.I., 2016. Necrotizing enterocolitis and preterm infant gut bacteria. Seminars in Fetal and Neonatal Medicine 21: 394-399.
    • (2016) Seminars in Fetal and Neonatal Medicine , vol.21 , pp. 394-399
    • Warner, B.B.1    Tarr, P.I.2
  • 113
    • 33645131324 scopus 로고    scopus 로고
    • In vitro fermentation of mixed linkage glucooligosaccharides produced by Gluconobacter oxydans NCIMB 4943 by the human colonic microflora
    • Wichienchot, S., Prasertsan, P., Hongpattarakere, T., Gibson, G.R. and Rastall, R.A., 2006. In vitro fermentation of mixed linkage glucooligosaccharides produced by Gluconobacter oxydans NCIMB 4943 by the human colonic microflora. Current Issues in Intestinal Microbiology 7: 7-12.
    • (2006) Current Issues in Intestinal Microbiology , vol.7 , pp. 7-12
    • Wichienchot, S.1    Prasertsan, P.2    Hongpattarakere, T.3    Gibson, G.R.4    Rastall, R.A.5
  • 114
    • 84884529566 scopus 로고    scopus 로고
    • Impact of dietary fiber fermentation from cereal grains on metabolite production by the fecal microbiota from normal weight and obese individuals
    • Yang, J., Keshavarzian, A. and Rose, D.J., 2013. Impact of dietary fiber fermentation from cereal grains on metabolite production by the fecal microbiota from normal weight and obese individuals. Journal of Medicinal Food 16: 862-867.
    • (2013) Journal of Medicinal Food , vol.16 , pp. 862-867
    • Yang, J.1    Keshavarzian, A.2    Rose, D.J.3
  • 115
    • 78049504915 scopus 로고    scopus 로고
    • Unexpected consequences of administering bacteriocinogenic probiotic strains for Salmonella populations, revealed by an in vitro colonic model of the child gut
    • Zihler, A., Gagnon, M., Chassard, C., Hegland, A., Stevens, M.J., Braegger, C.P. and Lacroix, C., 2010. Unexpected consequences of administering bacteriocinogenic probiotic strains for Salmonella populations, revealed by an in vitro colonic model of the child gut. Microbiology 156: 3342-3353.
    • (2010) Microbiology , vol.156 , pp. 3342-3353
    • Zihler, A.1    Gagnon, M.2    Chassard, C.3    Hegland, A.4    Stevens, M.J.5    Braegger, C.P.6    Lacroix, C.7
  • 116
    • 83455225495 scopus 로고    scopus 로고
    • Protective effect of probiotics on salmonella infectivity assessed with combined in vitro gut fermentation-cellular models
    • Zihler, A., Gagnon, M., Chassard, C. and Lacroix, C., 2011. Protective effect of probiotics on Salmonella infectivity assessed with combined in vitro gut fermentation-cellular models. BMC Microbiology 11: 264.
    • (2011) BMC Microbiology , vol.11 , pp. 264
    • Zihler, A.1    Gagnon, M.2    Chassard, C.3    Lacroix, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.