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Volumn 115, Issue 4, 2016, Pages 605-618

The piglet as a model for studying dietary components in infant diets: Effects of galacto-oligosaccharides on intestinal functions

Author keywords

Galacto oligosaccharides; Gut microbiota; Immunomodulation; Intestinal integrity; Neonatal piglet models

Indexed keywords

ACETIC ACID; ALPHA GLUCOSIDASE; BETA DEFENSIN 2; BUTYRIC ACID; DISACCHARIDASE; GALACTOSE OLIGOSACCHARIDE; LACTASE; LACTIC ACID; LACTOSE; MESSENGER RNA; PROPIONIC ACID; PROTEIN ZO1; SECRETORY IMMUNOGLOBULIN; SUCRASE; VALERIC ACID; BETA DEFENSIN; GALACTOSE; OLIGOSACCHARIDE; PREBIOTIC AGENT;

EID: 84956776076     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114515004997     Document Type: Article
Times cited : (75)

References (73)
  • 1
    • 84866066519 scopus 로고    scopus 로고
    • Early life: Gut microbiota and immune development in infancy
    • Martin R, Nauta AJ, Ben Amor K, et al. (2010) Early life: gut microbiota and immune development in infancy. Benef Microbes 1, 367-382.
    • (2010) Benef Microbes , vol.1 , pp. 367-382
    • Martin, R.1    Nauta, A.J.2    Ben Amor, K.3
  • 2
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL & Mazmanian SK (2009) The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9, 313-323.
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 3
    • 62449165965 scopus 로고    scopus 로고
    • Altered early infant gut microbiota in children developing allergy up to 5 years of age
    • Sjgren YM, Jenmalm MC, Bttcher MF, et al. (2009) Altered early infant gut microbiota in children developing allergy up to 5 years of age. Clin Exp Allergy 39, 518-526.
    • (2009) Clin Exp Allergy , vol.39 , pp. 518-526
    • Sjgren, Y.M.1    Jenmalm, M.C.2    Bttcher, M.F.3
  • 4
    • 74549117702 scopus 로고    scopus 로고
    • The importance of the development of the intestinal microbiota in infancy
    • Vael C & Desager K (2009) The importance of the development of the intestinal microbiota in infancy. Curr Opin Pediatr 21, 794-800.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 794-800
    • Vael, C.1    Desager, K.2
  • 5
    • 74849085312 scopus 로고    scopus 로고
    • Breast milk as the gold standard for protective nutrients
    • Walker A (2010) Breast milk as the gold standard for protective nutrients. J Pediatr 156, S3-S7.
    • (2010) J Pediatr , vol.156 , pp. S3-S7
    • Walker, A.1
  • 6
    • 84881244275 scopus 로고    scopus 로고
    • Intestinal microbiology in early life: Specific prebiotics can have similar functionalities as human-milk oligosaccharides
    • Oozeer R, van Limpt K, Ludwig T, et al. (2013) Intestinal microbiology in early life: specific prebiotics can have similar functionalities as human-milk oligosaccharides. Am J Clin Nutr 98, 561S-571S.
    • (2013) Am J Clin Nutr 98, 561S-571S
    • Oozeer, R.1    Van Limpt, K.2    Ludwig, T.3
  • 7
    • 44449168636 scopus 로고    scopus 로고
    • Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life
    • Arslanoglu S, Moro GE, Schmitt J, et al. (2008) Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 138, 1091-1095.
    • (2008) J Nutr , vol.138 , pp. 1091-1095
    • Arslanoglu, S.1    Moro, G.E.2    Schmitt, J.3
  • 8
    • 84881245841 scopus 로고    scopus 로고
    • Mechanisms underlying immune effects of dietary oligosaccharides
    • Jeurink PV, van Esch BC AM, Rijnierse A, et al. (2013) Mechanisms underlying immune effects of dietary oligosaccharides. Am J Clin Nutr 98, 572S-577S.
    • (2013) Am J Clin Nutr , vol.98 , pp. 572S-577S
    • Jeurink, P.V.1    Van Esch, B.C.A.M.2    Rijnierse, A.3
  • 9
    • 63649162938 scopus 로고    scopus 로고
    • Galactooligosaccharides are bifidogenic and safe at weaning: A double-blind randomized multicenter study
    • Fanaro S, Marten B, Bagna R, et al. (2009) Galactooligosaccharides are bifidogenic and safe at weaning: a double-blind randomized multicenter study. J Pediatr Gastroenterol Nutr 48, 82-88.
    • (2009) J Pediatr Gastroenterol Nutr , vol.48 , pp. 82-88
    • Fanaro, S.1    Marten, B.2    Bagna, R.3
  • 10
    • 59149093199 scopus 로고    scopus 로고
    • Clinical trial: The effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome
    • Silk DB A, Davis A, Vulevic J, et al. (2009) Clinical trial: the effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome. Aliment Pharmacol Ther 29, 508-518.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 508-518
    • Silk, D.B.A.1    Davis, A.2    Vulevic, J.3
  • 11
    • 84865246181 scopus 로고    scopus 로고
    • Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
    • Barnes JL, Hartmann B, Holst JJ, et al. (2012) Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. JPEN J Parenter Enteral Nutr 36, 524-537.
    • (2012) JPEN J Parenter Enteral Nutr , vol.36 , pp. 524-537
    • Barnes, J.L.1    Hartmann, B.2    Holst, J.J.3
  • 12
    • 79251513304 scopus 로고    scopus 로고
    • The incidence of necrotizing enterocolitis is increased following probiotic administration to preterm pigs
    • Cilieborg MS, Thymann T, Siggers R, et al. (2011) The incidence of necrotizing enterocolitis is increased following probiotic administration to preterm pigs. J Nutr 141, 223-230.
    • (2011) J Nutr , vol.141 , pp. 223-230
    • Cilieborg, M.S.1    Thymann, T.2    Siggers, R.3
  • 13
    • 84899554366 scopus 로고    scopus 로고
    • Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model
    • Wen K, Tin C, Wang H, et al. (2014) Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model. PLOS ONE 9, e94504.
    • (2014) PLOS ONE , vol.9 , pp. e94504
    • Wen, K.1    Tin, C.2    Wang, H.3
  • 14
    • 84884796095 scopus 로고    scopus 로고
    • The preterm pig as a model in pediatric gastroenterology
    • Sangild P, Thymann T, Schmidt M, et al. (2014) The preterm pig as a model in pediatric gastroenterology. J Anim Sci 91, 4713-4729.
    • (2014) J Anim Sci , vol.91 , pp. 4713-4729
    • Sangild, P.1    Thymann, T.2    Schmidt, M.3
  • 15
    • 84901834744 scopus 로고    scopus 로고
    • Use of pigs as a potential model for research into dietary modulation of the human gut microbiota
    • Heinritz SN, Mosenthin R & Weiss E (2013) Use of pigs as a potential model for research into dietary modulation of the human gut microbiota. Nutr Res Rev 26, 191-209.
    • (2013) Nutr Res Rev , vol.26 , pp. 191-209
    • Heinritz, S.N.1    Mosenthin, R.2    Weiss, E.3
  • 16
    • 84882682779 scopus 로고    scopus 로고
    • Prenatal gastrointestinal development in the pig and responses after preterm birth
    • Buddington R & Sangild P (2012) Prenatal gastrointestinal development in the pig and responses after preterm birth. J Anim Sci 90, 290-298.
    • (2012) J Anim Sci , vol.90 , pp. 290-298
    • Buddington, R.1    Sangild, P.2
  • 17
    • 33947501346 scopus 로고    scopus 로고
    • Early nutrition and immunity - Progress and perspectives
    • Calder PC, Krauss-etschmann S, De Jong EC, et al. (2006) Early nutrition and immunity - progress and perspectives. Br J Nutr 96, 774-790.
    • (2006) Br J Nutr , vol.96 , pp. 774-790
    • Calder, P.C.1    Krauss-Etschmann, S.2    De Jong, E.C.3
  • 18
    • 60849129156 scopus 로고    scopus 로고
    • A specific mixture of short-chain galacto-oligosaccharides and long-chain fructooligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy
    • Van Hoffen E, Ruiter B, Faber J, et al. (2009) A specific mixture of short-chain galacto-oligosaccharides and long-chain fructooligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy. Allergy 64, 484-487.
    • (2009) Allergy , vol.64 , pp. 484-487
    • Van Hoffen, E.1    Ruiter, B.2    Faber, J.3
  • 19
    • 27944432996 scopus 로고    scopus 로고
    • Effects of infant formula containing a mixture of galacto- and fructooligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life
    • Bakker-Zierikzee AM, Alles MS, Knol J, et al. (2007) Effects of infant formula containing a mixture of galacto- and fructooligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life. Br J Nutr 94, 783-790.
    • (2007) Br J Nutr , vol.94 , pp. 783-790
    • Bakker-Zierikzee, A.M.1    Alles, M.S.2    Knol, J.3
  • 20
    • 80052709142 scopus 로고    scopus 로고
    • Oligosaccharides in feces of breast- and formula-fed babies
    • Albrecht S, Schols HA, van Zoeren D, et al. (2011) Oligosaccharides in feces of breast- and formula-fed babies. Carbohydr Res 346, 2173-2181.
    • (2011) Carbohydr Res , vol.346 , pp. 2173-2181
    • Albrecht, S.1    Schols, H.A.2    Van Zoeren, D.3
  • 21
    • 84863588844 scopus 로고    scopus 로고
    • A randomised crossover study investigating the effects of galacto-oligosaccharides on the faecal microbiota in men and women over 50 years of age
    • Walton GE, van den Heuvel EGHM, Kosters MHW, et al. (2012) A randomised crossover study investigating the effects of galacto-oligosaccharides on the faecal microbiota in men and women over 50 years of age. Br J Nutr 107, 1466-1475.
    • (2012) Br J Nutr , vol.107 , pp. 1466-1475
    • Walton, G.E.1    Van Den Heuvel Eghm2    Mhw, K.3
  • 22
    • 33646099161 scopus 로고    scopus 로고
    • Quantitative PCR targeting 16S rRNA and reductive dehalogenase genes simultaneously monitors multiple Dehalococcoides strains
    • Ritalahti KM, Amos BK, Sung Y, et al. (2006) Quantitative PCR targeting 16S rRNA and reductive dehalogenase genes simultaneously monitors multiple Dehalococcoides strains. Appl Environ Microbiol 72, 2765-2774.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 2765-2774
    • Ritalahti, K.M.1    Amos, B.K.2    Sung, Y.3
  • 23
    • 84956835839 scopus 로고    scopus 로고
    • Bifidobacterium - The invention provides means and methods for detecting, amplifying, quantifying and/or isolating nucleic acid of at least one member of Bifidobacterium
    • patent EP 1 997 907
    • Nauta A, van den Heuvel EGHM, Veurink JH, et al. (2008) Bifidobacterium - the invention provides means and methods for detecting, amplifying, quantifying and/or isolating nucleic acid of at least one member of Bifidobacterium. European patent EP 1 997 907.
    • (2008) European
    • Nauta, A.1    Van Den Heuvel Eghm2    Veurink, J.H.3
  • 24
    • 84956751986 scopus 로고    scopus 로고
    • Lactobacillus - The invention provides means and methods for detecting, amplifying, quantifying and/or isolating nucleic acid of at least one Lactobacillus organism
    • patent EP 1 997 906 A1
    • Nauta A, van den Heuvel EGHM, Veurink JH, et al. (2008) Lactobacillus - the invention provides means and methods for detecting, amplifying, quantifying and/or isolating nucleic acid of at least one Lactobacillus organism. European patent EP 1 997 906 A1.
    • (2008) European
    • Nauta, A.1    Van Den Heuvel Eghm2    Veurink, J.H.3
  • 25
    • 0021347321 scopus 로고
    • Assay of intestinal disaccharidases
    • Dahlqvist A (1984) Assay of intestinal disaccharidases. Scand J Clin Lab Invest 44, 169-172.
    • (1984) Scand J Clin Lab Invest , vol.44 , pp. 169-172
    • Dahlqvist, A.1
  • 26
    • 34948893564 scopus 로고    scopus 로고
    • Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR
    • Nygard AB, Jrgensen CB, Cirera S, et al. (2007) Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR. BMC Mol Biol 8, 67.
    • (2007) BMC Mol Biol , vol.8 , pp. 67
    • Nygard, A.B.1    Jrgensen, C.B.2    Cirera, S.3
  • 29
    • 84855163623 scopus 로고    scopus 로고
    • IgG placental transfer in healthy and pathological pregnancies
    • Palmeira P, Quinello C, Silveira-Lessa AL, et al. (2012) IgG placental transfer in healthy and pathological pregnancies. Clin Exp Immunol 2012, 1-13.
    • (2012) Clin Exp Immunol , vol.2012 , pp. 1-13
    • Palmeira, P.1    Quinello, C.2    Silveira-Lessa, A.L.3
  • 30
    • 3042658607 scopus 로고    scopus 로고
    • Uptake of colostral immunoglobulins by the compromised newborn farm animal
    • Sangild T (2003) Uptake of colostral immunoglobulins by the compromised newborn farm animal. Acta Vet Scand Suppl 98, 105-122.
    • (2003) Acta Vet Scand Suppl , vol.98 , pp. 105-122
    • Sangild, T.1
  • 31
    • 46749145764 scopus 로고    scopus 로고
    • The immediate environment during postnatal development has long-term impact on gut community structure in pigs
    • Thompson CL, Wang B & Holmes AJ (2008) The immediate environment during postnatal development has long-term impact on gut community structure in pigs. ISME J 2, 739-748.
    • (2008) ISME J , vol.2 , pp. 739-748
    • Thompson, C.L.1    Wang, B.2    Holmes, A.J.3
  • 32
    • 0027299433 scopus 로고
    • Postnatal changes in selected bacterial groups of the pig colonic microflora
    • Swords WE, Wu CC, Champlin FR, et al. (1993) Postnatal changes in selected bacterial groups of the pig colonic microflora. Biol Neonate 63, 191-200.
    • (1993) Biol Neonate , vol.63 , pp. 191-200
    • Swords, W.E.1    Wu, C.C.2    Champlin, F.R.3
  • 33
    • 0141942752 scopus 로고    scopus 로고
    • Intestinal microflora in early infancy: Composition and development
    • Fanaro S, Chierici R, Guerrini P, et al. (2003) Intestinal microflora in early infancy: composition and development. Acta Paediatr Suppl 91, 48-55.
    • (2003) Acta Paediatr Suppl , vol.91 , pp. 48-55
    • Fanaro, S.1    Chierici, R.2    Guerrini, P.3
  • 34
    • 0032808645 scopus 로고    scopus 로고
    • Recent progress on research and applications of non-digestible galacto-oligosaccharides
    • Sako T, Matsumoto K & Tanaka R (1999) Recent progress on research and applications of non-digestible galacto-oligosaccharides. Int Dairy J 9, 69-80.
    • (1999) Int Dairy J , vol.9 , pp. 69-80
    • Sako, T.1    Matsumoto, K.2    Tanaka, R.3
  • 35
    • 84886820540 scopus 로고    scopus 로고
    • A quantitative and comprehensive method to analyze human milk oligosaccharide structures in the urine and feces of infants
    • De Leoz MLA, Wu S, Strum JS, et al. (2013) A quantitative and comprehensive method to analyze human milk oligosaccharide structures in the urine and feces of infants. Anal Bioanal Chem 405, 4089-4105.
    • (2013) Anal Bioanal Chem , vol.405 , pp. 4089-4105
    • De Leoz MLA1    Wu, S.2    Strum, J.S.3
  • 36
    • 84858335432 scopus 로고    scopus 로고
    • Vitro fermentation of 12 dietary fibres by faecal inoculum from pigs and humans
    • Jonathan MC, Van Den Borne JJGC, Van Wiechen P, et al. (2012) In vitro fermentation of 12 dietary fibres by faecal inoculum from pigs and humans. Food Chem 133, 889-897.
    • (2012) Food Chem , vol.133 , pp. 889-897
    • Jonathan, M.C.1    Van Den Borne Jjgc2    Van Wiechen, P.3
  • 37
    • 84891494259 scopus 로고    scopus 로고
    • Impact of galacto-oligosaccharides on the gut microbiota composition and metabolic activity upon antibiotic treatment during in vitro fermentation
    • Ladirat SE, Schuren FHJ, Schoterman MHC, et al. (2014) Impact of galacto-oligosaccharides on the gut microbiota composition and metabolic activity upon antibiotic treatment during in vitro fermentation. FEMS Microbiol Ecol 87, 41-51.
    • (2014) FEMS Microbiol Ecol , vol.87 , pp. 41-51
    • Ladirat, S.E.1    Fhj, S.2    Mhc, S.3
  • 38
    • 27944432996 scopus 로고    scopus 로고
    • Effects of infant formula containing a mixture of galacto- and fructooligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life
    • Bakker-Zierikzee AM, Alles MS, Knol J, et al. (2005) Effects of infant formula containing a mixture of galacto- and fructooligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life. Br J Nutr 94, 783-790.
    • (2005) Br J Nutr , vol.94 , pp. 783-790
    • Bakker-Zierikzee, A.M.1    Alles, M.S.2    Knol, J.3
  • 39
    • 84860571162 scopus 로고    scopus 로고
    • Effects of prebiotic-containing infant formula on gastrointestinal tolerance and fecal microbiota in a randomized controlled trial
    • Holscher HD, Faust KL, Czerkies LA, et al. (2012) Effects of prebiotic-containing infant formula on gastrointestinal tolerance and fecal microbiota in a randomized controlled trial. JPEN J Parenter Enteral Nutr 36, 95S-105S.
    • (2012) JPEN J Parenter Enteral Nutr 36, 95S-105S
    • Holscher, H.D.1    Faust, K.L.2    Czerkies, L.A.3
  • 40
    • 0032940447 scopus 로고    scopus 로고
    • Effect of nondigestible oligosaccharides on largebowel functions, blood lipid concentrations and glucose absorption in young healthy male subjects
    • Van Dokkum W, Wezendonk B, Srikumar TS, et al. (1999) Effect of nondigestible oligosaccharides on largebowel functions, blood lipid concentrations and glucose absorption in young healthy male subjects. Eur J Clin Nutr 53, 1-7.
    • (1999) Eur J Clin Nutr , vol.53 , pp. 1-7
    • Van Dokkum, W.1    Wezendonk, B.2    Srikumar, T.S.3
  • 41
    • 0031023319 scopus 로고    scopus 로고
    • Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats
    • Campbell JM, Fahey GC & Wolf BW (1997) Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats. J Nutr 127, 130-136.
    • (1997) J Nutr , vol.127 , pp. 130-136
    • Campbell, J.M.1    Fahey, G.C.2    Wolf, B.W.3
  • 42
    • 37149022209 scopus 로고    scopus 로고
    • Review article: The role of butyrate on colonic function
    • Hamer HM, Jonkers D, Venema K, et al. (2008) Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther 27, 104-119.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 104-119
    • Hamer, H.M.1    Jonkers, D.2    Venema, K.3
  • 43
    • 0030829647 scopus 로고    scopus 로고
    • Mucosal morphogenesis and cytodifferentiation in fetal porcine small intestine
    • Dekaney CM, Bazer FW & Jaeger LA (1997) Mucosal morphogenesis and cytodifferentiation in fetal porcine small intestine. Anat Rec 249, 517-523.
    • (1997) Anat Rec , vol.249 , pp. 517-523
    • Dekaney, C.M.1    Bazer, F.W.2    Jaeger, L.A.3
  • 44
    • 0029744696 scopus 로고    scopus 로고
    • Maintenance of villus height and crypt depth, and enhancement of disaccharide digestion and monosaccharide absorption, in piglets fed on cows whole milk after weaning
    • Pluske JR, Thompson MJ, Atwood CS, et al. (1996) Maintenance of villus height and crypt depth, and enhancement of disaccharide digestion and monosaccharide absorption, in piglets fed on cows whole milk after weaning. Br J Nutr 76, 409-422.
    • (1996) Br J Nutr , vol.76 , pp. 409-422
    • Pluske, J.R.1    Thompson, M.J.2    Atwood, C.S.3
  • 45
    • 79951675981 scopus 로고    scopus 로고
    • Addition of polydextrose and galactooligosaccharide to formula does not affect bacterial translocation in the neonatal piglet
    • Monaco MH, Kashtanov DO, Wang M, et al. (2011) Addition of polydextrose and galactooligosaccharide to formula does not affect bacterial translocation in the neonatal piglet. J Pediatr Gastroenterol Nutr 52, 210-216.
    • (2011) J Pediatr Gastroenterol Nutr , vol.52 , pp. 210-216
    • Monaco, M.H.1    Kashtanov, D.O.2    Wang, M.3
  • 46
    • 54449096412 scopus 로고    scopus 로고
    • Effects of chitooligosaccharide supplementation on the growth performance, nutrient digestibility, intestinal morphology, and fecal shedding of Escherichia coli and Lactobacillus in weaning pigs
    • Liu P, Piao XS, Kim SW, et al. (2008) Effects of chitooligosaccharide supplementation on the growth performance, nutrient digestibility, intestinal morphology, and fecal shedding of Escherichia coli and Lactobacillus in weaning pigs. J Anim Sci 86, 2609-2618.
    • (2008) J Anim Sci , vol.86 , pp. 2609-2618
    • Liu, P.1    Piao, X.S.2    Kim, S.W.3
  • 47
    • 84905730979 scopus 로고    scopus 로고
    • Cello-oligosaccharide influences intestinal microflora, mucosal architecture and nutrient transport in weaned pigs
    • Jiao LF, Song ZH, Ke YL, et al. (2014) Cello-oligosaccharide influences intestinal microflora, mucosal architecture and nutrient transport in weaned pigs. Anim Feed Sci Technol 195, 85-91.
    • (2014) Anim Feed Sci Technol , vol.195 , pp. 85-91
    • Jiao, L.F.1    Zh, S.2    Ke, Y.L.3
  • 48
    • 34247846235 scopus 로고    scopus 로고
    • Nutritional management of gut health in pigs around weaning
    • Lalls J-P, Bosi P, Smidt H, et al. (2007) Nutritional management of gut health in pigs around weaning. Proc Nutr Soc 66, 260-268.
    • (2007) Proc Nutr Soc , vol.66 , pp. 260-268
    • Lalls, J.-P.1    Bosi, P.2    Smidt, H.3
  • 49
  • 50
    • 84956749050 scopus 로고    scopus 로고
    • Influence of weaning age on the villous height and disaccharidase activities in the porcine small intestine
    • epublication ahead of print version 8 July
    • Tsukahara T, Inoue R, Nakatani M, et al. (2015) Influence of weaning age on the villous height and disaccharidase activities in the porcine small intestine. Anim Sci J (epublication ahead of print version 8 July 2015).
    • (2015) Anim Sci J , vol.2015
    • Tsukahara, T.1    Inoue, R.2    Nakatani, M.3
  • 51
    • 84882682779 scopus 로고    scopus 로고
    • Prenatal gastrointestinal development in the pig and responses after preterm birth
    • Buddington RK, Sangild PT, Hance B, et al. (2012) Prenatal gastrointestinal development in the pig and responses after preterm birth. J Anim Sci 90, 290-298.
    • (2012) J Anim Sci , vol.90 , pp. 290-298
    • Buddington, R.K.1    Sangild, P.T.2    Hance, B.3
  • 52
    • 0013934169 scopus 로고
    • Disaccharidase deficiency in infancy and childhood
    • Townley RR (1966) Disaccharidase deficiency in infancy and childhood. Pediatrics 38, 127-141.
    • (1966) Pediatrics , vol.38 , pp. 127-141
    • Townley, R.R.1
  • 53
    • 84882647844 scopus 로고    scopus 로고
    • The in vivo infusion of hydrogen peroxide induces oxidative stress and differentially affects the activities of small intestinal carbohydrate digestive enzymes in the neonatal pig
    • Lackeyram D, Mine Y, Widowski T, et al. (2012) The in vivo infusion of hydrogen peroxide induces oxidative stress and differentially affects the activities of small intestinal carbohydrate digestive enzymes in the neonatal pig. J Anim Sci 90, 418-420.
    • (2012) J Anim Sci , vol.90 , pp. 418-420
    • Lackeyram, D.1    Mine, Y.2    Widowski, T.3
  • 54
    • 38349181488 scopus 로고    scopus 로고
    • Bacterial metabolism and health-related effects of galactooligosaccharides and other prebiotics
    • Macfarlane GT, Steed H & Macfarlane S (2008) Bacterial metabolism and health-related effects of galactooligosaccharides and other prebiotics. J Appl Microbiol 104, 305-344.
    • (2008) J Appl Microbiol , vol.104 , pp. 305-344
    • Macfarlane, G.T.1    Steed, H.2    Macfarlane, S.3
  • 55
    • 84873716991 scopus 로고    scopus 로고
    • Regulation of intestinal epithelial permeability by tight junctions
    • Suzuki T (2013) Regulation of intestinal epithelial permeability by tight junctions. Cell Mol Life Sci 70, 631-659.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 631-659
    • Suzuki, T.1
  • 56
    • 84882797836 scopus 로고    scopus 로고
    • Intestinal permeability defects: Is it time to treat?
    • Odenwald MA & Turner JR (2013) Intestinal permeability defects: is it time to treat? Clin Gastroenterol Hepatol 11, 1075-1083.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 1075-1083
    • Odenwald, M.A.1    Turner, J.R.2
  • 57
    • 84919777118 scopus 로고    scopus 로고
    • Glutamine enhances tight junction protein expression and modulates corticotropinreleasing factor signaling in the jejunum of weanling piglets
    • Wang H, Zhang C, Wu G, et al. (2015) Glutamine enhances tight junction protein expression and modulates corticotropinreleasing factor signaling in the jejunum of weanling piglets. J Nutr 145, 25-31.
    • (2015) J Nutr , vol.145 , pp. 25-31
    • Wang, H.1    Zhang, C.2    Wu, G.3
  • 58
    • 34948841529 scopus 로고    scopus 로고
    • Gradual disappearance of vacuolated enterocytes in the small intestine of neonatal piglets
    • Skrzypek T, Valverde Piedra JL, Skrzypek H, et al. (2007) Gradual disappearance of vacuolated enterocytes in the small intestine of neonatal piglets. J Physiol Pharmacol 58, 87-95.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 87-95
    • Skrzypek, T.1    Valverde Piedra, J.L.2    Skrzypek, H.3
  • 59
    • 0020045976 scopus 로고
    • Gastrointestinal permeability changes in the preterm neonate
    • Beach RC, Menzies IS, Clayden GS, et al. (1982) Gastrointestinal permeability changes in the preterm neonate. Arch Dis Child 57, 141-145.
    • (1982) Arch Dis Child , vol.57 , pp. 141-145
    • Beach, R.C.1    Menzies, I.S.2    Clayden, G.S.3
  • 60
    • 84935444515 scopus 로고    scopus 로고
    • Galactooligosaccharides protect the intestinal barrier by maintaining the tight junction network and modulating the inflammatory responses after a challenge with the mycotoxin deoxynivalenol in human Caco-2 cell monolayers and B6C3F1 mice
    • Akbari P, Braber S, Alizadeh A, et al. (2015) Galactooligosaccharides protect the intestinal barrier by maintaining the tight junction network and modulating the inflammatory responses after a challenge with the mycotoxin deoxynivalenol in human Caco-2 cell monolayers and B6C3F1 mice. J Nutr 145, 1604-1613.
    • (2015) J Nutr , vol.145 , pp. 1604-1613
    • Akbari, P.1    Braber, S.2    Alizadeh, A.3
  • 61
    • 33846974390 scopus 로고    scopus 로고
    • Effects of butyrate on intestinal barrier function in a Caco-2 cell monolayer model of intestinal barrier
    • Peng L, He Z, Chen W, et al. (2007) Effects of butyrate on intestinal barrier function in a Caco-2 cell monolayer model of intestinal barrier. Pediatr Res 61, 37-41.
    • (2007) Pediatr Res , vol.61 , pp. 37-41
    • Peng, L.1    He, Z.2    Chen, W.3
  • 62
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani PD, Possemiers S, Van de Wiele T, et al. (2009) Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58, 1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van De Wiele, T.3
  • 63
    • 84907879234 scopus 로고    scopus 로고
    • A review of the innate immune defence of the human foetus and newborn, with the emphasis on antimicrobial peptides
    • Kai-Larsen Y, Gudmundsson GH & Agerberth B (2014) A review of the innate immune defence of the human foetus and newborn, with the emphasis on antimicrobial peptides. Acta Paediatr 103, 1000-1008.
    • (2014) Acta Paediatr , vol.103 , pp. 1000-1008
    • Kai-Larsen, Y.1    Gudmundsson, G.H.2    Agerberth, B.3
  • 64
    • 38549171792 scopus 로고    scopus 로고
    • Probiotic Lactobacilli and VSL#3 induce enterocyte β-defensin 2
    • Schlee M, Harder J, K?ten B, et al. (2008) Probiotic Lactobacilli and VSL#3 induce enterocyte ?-defensin 2. Clin Exp Immunol 151, 528-535.
    • (2008) Clin Exp Immunol , vol.151 , pp. 528-535
    • Schlee, M.1    Harder, J.2    Kten, B.3
  • 65
    • 34548290744 scopus 로고    scopus 로고
    • Porcine beta-defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria
    • Veldhuizen EJA, Rijnders M, Claassen EA, et al. (2008) Porcine beta-defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria. Mol Immunol 45, 386-394.
    • (2008) Mol Immunol , vol.45 , pp. 386-394
    • Eja, V.1    Rijnders, M.2    Claassen, E.A.3
  • 66
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg P (2007) Induction of secretory immunity and memory at mucosal surfaces. Vaccine 25, 5467-5484.
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 67
    • 0033979854 scopus 로고    scopus 로고
    • Probiotic immunomodulation in health and disease
    • Erickson KL & Hubbard NE (2000) Probiotic immunomodulation in health and disease. J Nutr 130, 403S-409S.
    • (2000) J Nutr , vol.130 , pp. 403S-409S
    • Erickson, K.L.1    Hubbard, N.E.2
  • 68
    • 0038107877 scopus 로고    scopus 로고
    • Development of the intestinal microbiota in rats and its possible interactions with the evolution of the luminal IgA in the intestine
    • Inoue R & Ushida K (2003) Development of the intestinal microbiota in rats and its possible interactions with the evolution of the luminal IgA in the intestine. FEMS Microbiol Ecol 45, 147-153.
    • (2003) FEMS Microbiol Ecol , vol.45 , pp. 147-153
    • Inoue, R.1    Ushida, K.2
  • 69
    • 27244433454 scopus 로고    scopus 로고
    • Development of the intestinal microbiota in the piglet
    • Inoue R, Tsukahara T, Nakanishi N, et al. (2005) Development of the intestinal microbiota in the piglet. J Gen Appl Microbiol 51, 257-265.
    • (2005) J Gen Appl Microbiol , vol.51 , pp. 257-265
    • Inoue, R.1    Tsukahara, T.2    Nakanishi, N.3
  • 70
    • 0034962960 scopus 로고    scopus 로고
    • Influence of resident intestinal microflora on the development and functions of the gut-associated lymphoid tissue
    • Moreau M-C & Gaboriau-Routhiau V (2001) Influence of resident intestinal microflora on the development and functions of the gut-associated lymphoid tissue. Microb Ecol Heal Dis 13, 65-86.
    • (2001) Microb Ecol Heal Dis , vol.13 , pp. 65-86
    • Moreau, M.-C.1    Gaboriau-Routhiau, V.2
  • 71
    • 0032935617 scopus 로고    scopus 로고
    • Influences of microbiota on intestinal immune system development
    • Cebra JJ (1999) Influences of microbiota on intestinal immune system development. Am J Clin Nutr 69, 1046S-1051S.
    • (1999) Am J Clin Nutr 69, 1046S-1051S
    • Cebra, J.J.1
  • 72
    • 44449090539 scopus 로고    scopus 로고
    • Fecal secretory immunoglobulin A is increased in healthy infants who receive a formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides
    • Scholtens PAMJ, Alliet P, Raes M, et al. (2008) Fecal secretory immunoglobulin A is increased in healthy infants who receive a formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides. J Nutr 138, 1141-1147.
    • (2008) J Nutr , vol.138 , pp. 1141-1147
    • Pamj, S.1    Alliet, P.2    Raes, M.3
  • 73
    • 84920594238 scopus 로고    scopus 로고
    • Breast milk, microbiota, and intestinal immune homeostasis
    • Walker WA & Iyengar RS (2015) Breast milk, microbiota, and intestinal immune homeostasis. Pediatr Res 77, 220-228.
    • (2015) Pediatr Res , vol.77 , pp. 220-228
    • Walker, W.A.1    Iyengar, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.