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Volumn 84, Issue 1, 2013, Pages 110-123

Effect of galactooligosaccharides and Bifidobacterium animalis Bb-12 on growth of Lactobacillus amylovorus DSM 16698, microbial community structure, and metabolite production in an in vitro colonic model set up with human or pig microbiota

Author keywords

16S rRNA gene targeted qPCR; Galactooligosaccharides; Metabolites; PCR DGGE; Probiotic; TIM 2

Indexed keywords

GALACTOSE; OLIGOSACCHARIDE; PREBIOTIC AGENT; PROBIOTIC AGENT; RNA 16S; VOLATILE FATTY ACID;

EID: 84874673579     PISSN: 01686496     EISSN: 15746941     Source Type: Journal    
DOI: 10.1111/1574-6941.12041     Document Type: Article
Times cited : (33)

References (70)
  • 2
    • 66149085766 scopus 로고    scopus 로고
    • Introducing capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) for the characterization of konjac glucomannan oligosaccharides and their in vitro fermentation behavior
    • Albrecht S, van Muiswinkel GC, Schols HA, Voragen AG & Gruppen H (2009) Introducing capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) for the characterization of konjac glucomannan oligosaccharides and their in vitro fermentation behavior. J Agric Food Chem 57: 3867-3876.
    • (2009) J Agric Food Chem , vol.57 , pp. 3867-3876
    • Albrecht, S.1    van Muiswinkel, G.C.2    Schols, H.A.3    Voragen, A.G.4    Gruppen, H.5
  • 3
    • 77949398346 scopus 로고    scopus 로고
    • Introducing capillary electrophoresis with laser-induced fluorescence (CE-LIF) as a potential analysis and quantification tool for galactooligosaccharides extracted from complex food matrices
    • Albrecht S, Schols HA, Klarenbeek B, Voragen AGJ & Gruppen H (2010) Introducing capillary electrophoresis with laser-induced fluorescence (CE-LIF) as a potential analysis and quantification tool for galactooligosaccharides extracted from complex food matrices. J Agric Food Chem 58: 2787-2794.
    • (2010) J Agric Food Chem , vol.58 , pp. 2787-2794
    • Albrecht, S.1    Schols, H.A.2    Klarenbeek, B.3    Voragen, A.G.J.4    Gruppen, H.5
  • 4
    • 84858709310 scopus 로고    scopus 로고
    • Freezing fecal samples prior to DNA extraction affects the Firmicutes to Bacteroides ratio determined by downstream quantitative PCR analysis
    • Bahl MI, Bergström A & Licht TN (2012) Freezing fecal samples prior to DNA extraction affects the Firmicutes to Bacteroides ratio determined by downstream quantitative PCR analysis. FEMS Microbiol Lett 329: 193-197.
    • (2012) FEMS Microbiol Lett , vol.329 , pp. 193-197
    • Bahl, M.I.1    Bergström, A.2    Licht, T.N.3
  • 5
    • 33751516099 scopus 로고    scopus 로고
    • Health management with reduced antibiotic use - the U.S. experience
    • Baker R (2006) Health management with reduced antibiotic use - the U.S. experience. Anim Biotechnol 17: 195-205.
    • (2006) Anim Biotechnol , vol.17 , pp. 195-205
    • Baker, R.1
  • 6
    • 0030891419 scopus 로고    scopus 로고
    • Administration of transgalacto-oligosaccharides increases fecal bifidobacteria and modifies colonic fermentation metabolism in healthy humans
    • Bouhnik Y, Flouré B, D'Agay-Abensour L, Pochart P, Gramet G, Durand M & Rambaud JC (1997) Administration of transgalacto-oligosaccharides increases fecal bifidobacteria and modifies colonic fermentation metabolism in healthy humans. J Nutr 127: 444-448.
    • (1997) J Nutr , vol.127 , pp. 444-448
    • Bouhnik, Y.1    Flouré, B.2    D'Agay-Abensour, L.3    Pochart, P.4    Gramet, G.5    Durand, M.6    Rambaud, J.C.7
  • 7
    • 21244503098 scopus 로고    scopus 로고
    • Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident
    • Bourriaud C, Robins RJ, Martin L, Kozlowski S, Tenailleau E, Cherbut C & Michel C (2005) Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident. J Appl Microbiol 99: 201-212.
    • (2005) J Appl Microbiol , vol.99 , pp. 201-212
    • Bourriaud, C.1    Robins, R.J.2    Martin, L.3    Kozlowski, S.4    Tenailleau, E.5    Cherbut, C.6    Michel, C.7
  • 10
    • 11844257332 scopus 로고    scopus 로고
    • Acidified milk formula supplemented with Bifidobacterium lactis: impact on infant diarrhea in residential care settings
    • Chouraqui JP, Van Egroo LD & Fichot MC (2004) Acidified milk formula supplemented with Bifidobacterium lactis: impact on infant diarrhea in residential care settings. J Pediatr Gastroenterol Nutr 38: 288-292.
    • (2004) J Pediatr Gastroenterol Nutr , vol.38 , pp. 288-292
    • Chouraqui, J.P.1    Van Egroo, L.D.2    Fichot, M.C.3
  • 12
    • 8144224956 scopus 로고    scopus 로고
    • Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product
    • Duncan SH, Louis P & Flint HJ (2004) Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol 70: 5810-5817.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 5810-5817
    • Duncan, S.H.1    Louis, P.2    Flint, H.J.3
  • 14
    • 0024117598 scopus 로고
    • Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria
    • Gibson GR, Cummings JH & Macfarlane GT (1988) Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria. Appl Environ Microbiol 54: 2750-2755.
    • (1988) Appl Environ Microbiol , vol.54 , pp. 2750-2755
    • Gibson, G.R.1    Cummings, J.H.2    Macfarlane, G.T.3
  • 15
    • 0028933106 scopus 로고
    • Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin
    • Gibson GR, Beatty ER, Wang X & Cummings JH (1995) Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology 108: 975-982.
    • (1995) Gastroenterology , vol.108 , pp. 975-982
    • Gibson, G.R.1    Beatty, E.R.2    Wang, X.3    Cummings, J.H.4
  • 16
    • 0030891627 scopus 로고    scopus 로고
    • Effects of high and low risk diets on gut-microflora-associated biomarkers of colon cancer in human-flora-associated rats
    • Hambly RJ, Rumney CJ, Fletcher JME, Rijken P & Rowland IR (1997) Effects of high and low risk diets on gut-microflora-associated biomarkers of colon cancer in human-flora-associated rats. Nutr Cancer 27: 250-255.
    • (1997) Nutr Cancer , vol.27 , pp. 250-255
    • Hambly, R.J.1    Rumney, C.J.2    Fletcher, J.M.E.3    Rijken, P.4    Rowland, I.R.5
  • 18
    • 0031042629 scopus 로고    scopus 로고
    • Lack of butyrate is associated with induction of bax and subsequent apoptosis in the proximal colon of guinea pig
    • Hass R, Busche R, Luciano L, Reale E & Engelhardt W (1997) Lack of butyrate is associated with induction of bax and subsequent apoptosis in the proximal colon of guinea pig. Gastroenterology 112: 875-881.
    • (1997) Gastroenterology , vol.112 , pp. 875-881
    • Hass, R.1    Busche, R.2    Luciano, L.3    Reale, E.4    Engelhardt, W.5
  • 19
    • 80053026224 scopus 로고    scopus 로고
    • Intestinal health functions of colonic microbial metabolites: a review
    • Havenaar R (2011) Intestinal health functions of colonic microbial metabolites: a review. Benef Microbes 2: 103-114.
    • (2011) Benef Microbes , vol.2 , pp. 103-114
    • Havenaar, R.1
  • 20
    • 0036139245 scopus 로고    scopus 로고
    • Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA
    • Heilig HG, Zoetendal EG, Vaughan EE, Marteau P, Akkermans ADL & de Vos WM (2002) Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA. Appl Environ Microbiol 68: 114-123.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 114-123
    • Heilig, H.G.1    Zoetendal, E.G.2    Vaughan, E.E.3    Marteau, P.4    Akkermans, A.D.L.5    de Vos, W.M.6
  • 22
    • 84860547631 scopus 로고    scopus 로고
    • Bifidobacterium lactis Bb12 enhances intestinal antibody response in formula-fed infants: a randomized, double-blind, controlled trial
    • Holscher HD, Czerkies LA, Cekola P et al. (2012) Bifidobacterium lactis Bb12 enhances intestinal antibody response in formula-fed infants: a randomized, double-blind, controlled trial. J Parenter Enter Nutr 36: 106-117.
    • (2012) J Parenter Enter Nutr , vol.36 , pp. 106-117
    • Holscher, H.D.1    Czerkies, L.A.2    Cekola, P.3
  • 24
    • 47249114865 scopus 로고    scopus 로고
    • Lactobacillus sobrius Konstantinov 2006 is a later synonym of Lactobacillus amylovorus Nakamura 1981
    • Jakava-Viljanen M, Murros A, Palva A & Björkroth KJ (2008) Lactobacillus sobrius Konstantinov et al. 2006 is a later synonym of Lactobacillus amylovorus Nakamura 1981. Int J Syst Bacteriol 58: 910-933.
    • (2008) Int J Syst Bacteriol , vol.58 , pp. 910-933
    • Jakava-Viljanen, M.1    Murros, A.2    Palva, A.3    Björkroth, K.J.4
  • 25
    • 32044463785 scopus 로고    scopus 로고
    • Representative difference analysis and real-time PCR for strain specific quantification of Lactobacillus sobrius sp. nov
    • Konstantinov SR, Smidt H & de Vos WM (2005) Representative difference analysis and real-time PCR for strain specific quantification of Lactobacillus sobrius sp. nov. Appl Environ Microbiol 71: 7578-7581.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 7578-7581
    • Konstantinov, S.R.1    Smidt, H.2    de Vos, W.M.3
  • 29
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S & Gordon JL (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.L.4
  • 30
    • 77956615418 scopus 로고    scopus 로고
    • In-vitro assessment of the effects of dietary fibers on microbial fermentation and communities from large intestinal digesta of pigs
    • Lin B, Gong J, Wang Q, Cui S, Yu H & Huang B (2011) In-vitro assessment of the effects of dietary fibers on microbial fermentation and communities from large intestinal digesta of pigs. Food Hydrocoll 25: 180-188.
    • (2011) Food Hydrocoll , vol.25 , pp. 180-188
    • Lin, B.1    Gong, J.2    Wang, Q.3    Cui, S.4    Yu, H.5    Huang, B.6
  • 31
    • 77955858070 scopus 로고    scopus 로고
    • The effect of the undigested fraction of maize products on the activity and composition of the microbiota determined in a dynamic in vitro model of the human proximal large intestine
    • Maathuis A, Hoffman A, Evans A, Sanders L & Venema K (2009) The effect of the undigested fraction of maize products on the activity and composition of the microbiota determined in a dynamic in vitro model of the human proximal large intestine. J Am Coll Nutr 28: 657-666.
    • (2009) J Am Coll Nutr , vol.28 , pp. 657-666
    • Maathuis, A.1    Hoffman, A.2    Evans, A.3    Sanders, L.4    Venema, K.5
  • 32
    • 15544382565 scopus 로고    scopus 로고
    • Immunity, inflammation, and allergy in the gut
    • Macdonald TJ & Monteleone G (2005) Immunity, inflammation, and allergy in the gut. Science 307: 1920-1925.
    • (2005) Science , vol.307 , pp. 1920-1925
    • Macdonald, T.J.1    Monteleone, G.2
  • 35
    • 38349181488 scopus 로고    scopus 로고
    • Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics
    • Macfarlane GT, Steed H & Macfarlane S (2008) Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 104: 305-344.
    • (2008) J Appl Microbiol , vol.104 , pp. 305-344
    • Macfarlane, G.T.1    Steed, H.2    Macfarlane, S.3
  • 36
    • 79960846404 scopus 로고    scopus 로고
    • In vitro evaluation of gastrointestinal survival of Lactobacillus amylovorus DSM 16698 alone and combined with galactooligosaccharides, milk, and/or Bifidobacterium animalis subsp. lactis Bb-12
    • Martinez RCR, Aynaou A-E, Albrecht S, Schols HA, De Martinis ECP, Zoetendal EG, Venema K, Saad SMI & Smidt S (2011) In vitro evaluation of gastrointestinal survival of Lactobacillus amylovorus DSM 16698 alone and combined with galactooligosaccharides, milk, and/or Bifidobacterium animalis subsp. lactis Bb-12. Int J Food Microbiol 149: 152-158.
    • (2011) Int J Food Microbiol , vol.149 , pp. 152-158
    • Martinez, R.C.R.1    Aynaou, A.-E.2    Albrecht, S.3    Schols, H.A.4    De Martinis, E.C.P.5    Zoetendal, E.G.6    Venema, K.7    Saad, S.M.I.8    Smidt, S.9
  • 37
    • 0345869650 scopus 로고    scopus 로고
    • Quantitative PCR with 16S rRNA-gene-targeted species-specific primers for analysis of human intestinal bifidobacteria
    • Matsuki T, Watanabe K, Fujimoto J, Kado Y, Takada T, Matsumoto K & Tanaka R (2004) Quantitative PCR with 16S rRNA-gene-targeted species-specific primers for analysis of human intestinal bifidobacteria. Appl Environ Microbiol 70: 167-173.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 167-173
    • Matsuki, T.1    Watanabe, K.2    Fujimoto, J.3    Kado, Y.4    Takada, T.5    Matsumoto, K.6    Tanaka, R.7
  • 38
    • 0034861484 scopus 로고    scopus 로고
    • Modulation of genotoxic enzyme activities by non-digestible oligosaccharide metabolism in in vitro human gut bacterial ecosystems
    • McBain AJ & MacFarlane GT (2001) Modulation of genotoxic enzyme activities by non-digestible oligosaccharide metabolism in in vitro human gut bacterial ecosystems. J Med Microbiol 50: 833-842.
    • (2001) J Med Microbiol , vol.50 , pp. 833-842
    • McBain, A.J.1    MacFarlane, G.T.2
  • 40
    • 33750939835 scopus 로고    scopus 로고
    • Effects of Bifidobacterium lactis Bb12 supplementation on intestinal microbiota of preterm infants: a double-blind, placebo-controlled, randomized study
    • Mohan R, Koebnick C, Schildt J, Schmidt S & Mueller M (2006) Effects of Bifidobacterium lactis Bb12 supplementation on intestinal microbiota of preterm infants: a double-blind, placebo-controlled, randomized study. J Clin Microbiol 44: 4025-4031.
    • (2006) J Clin Microbiol , vol.44 , pp. 4025-4031
    • Mohan, R.1    Koebnick, C.2    Schildt, J.3    Schmidt, S.4    Mueller, M.5
  • 41
    • 0027460328 scopus 로고
    • Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA
    • Muyzer G, de Waal EC & Uitterlinden AG (1993) Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Appl Environ Microbiol 59: 695-700.
    • (1993) Appl Environ Microbiol , vol.59 , pp. 695-700
    • Muyzer, G.1    de Waal, E.C.2    Uitterlinden, A.G.3
  • 42
    • 0023476285 scopus 로고
    • Detection and localization of single base changes by denaturing gradient gel electrophoresis
    • Myers RM, Maniatism T & Lerman LS (1987) Detection and localization of single base changes by denaturing gradient gel electrophoresis. Methods Enzymol 155: 501-527.
    • (1987) Methods Enzymol , vol.155 , pp. 501-527
    • Myers, R.M.1    Maniatism, T.2    Lerman, L.S.3
  • 43
    • 0029796310 scopus 로고    scopus 로고
    • Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis
    • Nübel U, Engelen B, Felske A, Snaidr J, Wieshuber A, Amann RI, Ludwig W & Backhaus H (1996) Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis. J Bacteriol 178: 5636-5643.
    • (1996) J Bacteriol , vol.178 , pp. 5636-5643
    • Nübel, U.1    Engelen, B.2    Felske, A.3    Snaidr, J.4    Wieshuber, A.5    Amann, R.I.6    Ludwig, W.7    Backhaus, H.8
  • 44
    • 46449118663 scopus 로고    scopus 로고
    • The pig as experimental model for elucidating the mechanisms governing dietary influence on mineral absorption
    • Patterson JK, Lei XG & Miller DD (2008) The pig as experimental model for elucidating the mechanisms governing dietary influence on mineral absorption. Exp Biol Med 233: 651-654.
    • (2008) Exp Biol Med , vol.233 , pp. 651-654
    • Patterson, J.K.1    Lei, X.G.2    Miller, D.D.3
  • 45
    • 67650261083 scopus 로고    scopus 로고
    • Denaturing gradient gel electrophoresis (DGGE)-based monitoring of intestinal lactobacilli and bifidobacteria of pigs during a feeding trial
    • Petersson A, Domig KJ, Nagel P, Zollitsch W, Hagmüller W & Kneifel W (2009) Denaturing gradient gel electrophoresis (DGGE)-based monitoring of intestinal lactobacilli and bifidobacteria of pigs during a feeding trial. Arch Anim Nutr 63: 112-116.
    • (2009) Arch Anim Nutr , vol.63 , pp. 112-116
    • Petersson, A.1    Domig, K.J.2    Nagel, P.3    Zollitsch, W.4    Hagmüller, W.5    Kneifel, W.6
  • 46
    • 77649275204 scopus 로고    scopus 로고
    • Prebiotics and probiotics; modifying and mining the microbiota
    • Quigley EMM (2010) Prebiotics and probiotics; modifying and mining the microbiota. Pharmacol Res 61: 213-218.
    • (2010) Pharmacol Res , vol.61 , pp. 213-218
    • Quigley, E.M.M.1
  • 47
    • 78049502175 scopus 로고    scopus 로고
    • Evaluating the microbial diversity of an in vitro model of the large intestine by phylogenetic microarray analysis
    • Rajilić-Stojanovic M, Maathuis A, Heilig HG, Venema K, de Vos VM & Smidt H (2010) Evaluating the microbial diversity of an in vitro model of the large intestine by phylogenetic microarray analysis. Microbiology 156: 3270-3281.
    • (2010) Microbiology , vol.156 , pp. 3270-3281
    • Rajilić-Stojanovic, M.1    Maathuis, A.2    Heilig, H.G.3    Venema, K.4    de Vos, V.M.5    Smidt, H.6
  • 48
    • 35848940262 scopus 로고    scopus 로고
    • Inulin-type fructans: functional food ingredients
    • Roberfroid MB (2007) Inulin-type fructans: functional food ingredients. J Nutr 137: S2493-S2502.
    • (2007) J Nutr , vol.137
    • Roberfroid, M.B.1
  • 49
    • 37149036876 scopus 로고    scopus 로고
    • The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage
    • Roselli M, Finamore A, Britti MS, Konstantinov SR, Smidt H, de Vos WM & Mengheri E (2007) The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage. J Nutr 137: 2709-2716.
    • (2007) J Nutr , vol.137 , pp. 2709-2716
    • Roselli, M.1    Finamore, A.2    Britti, M.S.3    Konstantinov, S.R.4    Smidt, H.5    de Vos, W.M.6    Mengheri, E.7
  • 50
    • 0028116158 scopus 로고
    • Rapid silver staining and recovery of PCR products separated on polyacrylamide gels
    • Sanguinetti CJ, Dias Neto E & Simpson AJ (1994) Rapid silver staining and recovery of PCR products separated on polyacrylamide gels. Biotechniques 17: 914-921.
    • (1994) Biotechniques , vol.17 , pp. 914-921
    • Sanguinetti, C.J.1    Dias Neto, E.2    Simpson, A.J.3
  • 51
    • 35948957475 scopus 로고    scopus 로고
    • Differences in faecal bacterial communities in coeliac and healthy children as detected by PCR and denaturing gradient gel electrophoresis
    • Sanz Y, Sánchez E, Marzotto M, Calabuig M, Torriani S & Dellagio F (2007) Differences in faecal bacterial communities in coeliac and healthy children as detected by PCR and denaturing gradient gel electrophoresis. FEMS Immunol Med Microbiol 51: 562-568.
    • (2007) FEMS Immunol Med Microbiol , vol.51 , pp. 562-568
    • Sanz, Y.1    Sánchez, E.2    Marzotto, M.3    Calabuig, M.4    Torriani, S.5    Dellagio, F.6
  • 52
    • 0035146181 scopus 로고    scopus 로고
    • Bifidobacterial diversity in human feces detected by genus-specific PCR and denaturing gradient gel electrophoresis
    • Satokari RM, Vaughan EE, Akkermans ADI, Saarela M & de Vos WM (2001) Bifidobacterial diversity in human feces detected by genus-specific PCR and denaturing gradient gel electrophoresis. Appl Environ Microbiol 67: 504-513.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 504-513
    • Satokari, R.M.1    Vaughan, E.E.2    Akkermans, A.D.I.3    Saarela, M.4    de Vos, W.M.5
  • 53
    • 0028126050 scopus 로고
    • Effects of short chain fatty acids on gut morphology and function
    • Scheppach W (1994) Effects of short chain fatty acids on gut morphology and function. Gut 35: 35-38.
    • (1994) Gut , vol.35 , pp. 35-38
    • Scheppach, W.1
  • 54
    • 0035074712 scopus 로고    scopus 로고
    • Beneficial health effects of low digestible carbohydrate consumption
    • Scheppach W, Luehrs H & Menzel T (2001) Beneficial health effects of low digestible carbohydrate consumption. Br J Nutr 85: S23-S30.
    • (2001) Br J Nutr , vol.85
    • Scheppach, W.1    Luehrs, H.2    Menzel, T.3
  • 56
    • 84864510414 scopus 로고    scopus 로고
    • Effects of dietary fibers with different physicochemical properties on feeding motivation in adult female pigs
    • Souza da Silva C, van den Borne JJGC, Gerrits WJJ, Kemp B & Bolhuis JE (2012) Effects of dietary fibers with different physicochemical properties on feeding motivation in adult female pigs. Physiol Behav 107: 218-230.
    • (2012) Physiol Behav , vol.107 , pp. 218-230
    • Souza da Silva, C.1    van den Borne, J.J.G.C.2    Gerrits, W.J.J.3    Kemp, B.4    Bolhuis, J.E.5
  • 57
    • 0033760479 scopus 로고    scopus 로고
    • Quantitative analysis of small-subunit rRNA genes in mixed microbial populations via 5′-nuclease assays
    • Suzuki MT, Beja O, Taylor LT & Delong EF (2000) Quantitative analysis of small-subunit rRNA genes in mixed microbial populations via 5′-nuclease assays. Appl Environ Microbiol 66: 4605-4614.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 4605-4614
    • Suzuki, M.T.1    Beja, O.2    Taylor, L.T.3    Delong, E.F.4
  • 58
    • 22144484491 scopus 로고    scopus 로고
    • A novel galactooligosaccharide mixture increases the bifidobacterial population numbers in a continuous in vitro fermentation system and in the proximal colonic contents of pigs in vivo
    • Tzortzis G, Goulas AK, Geen JM & Gibson GR (2005) A novel galactooligosaccharide mixture increases the bifidobacterial population numbers in a continuous in vitro fermentation system and in the proximal colonic contents of pigs in vivo. J Nutr 135: 1726-1731.
    • (2005) J Nutr , vol.135 , pp. 1726-1731
    • Tzortzis, G.1    Goulas, A.K.2    Geen, J.M.3    Gibson, G.R.4
  • 59
    • 0345257151 scopus 로고    scopus 로고
    • The effect of various inulins and Clostridium difficile on the metabolic activity of the human colonic microbiota in vitro
    • Van Nuenen HMC, Meyer PD & Venema K (2003) The effect of various inulins and Clostridium difficile on the metabolic activity of the human colonic microbiota in vitro. Microb Ecol Health Dis 15: 137-144.
    • (2003) Microb Ecol Health Dis , vol.15 , pp. 137-144
    • Van Nuenen, H.M.C.1    Meyer, P.D.2    Venema, K.3
  • 60
    • 33748780623 scopus 로고    scopus 로고
    • Molecular monitoring of the fecal microbiota of healthy human subjects during administration of lactulose and Saccharomyces boulardii
    • Vanhoutte T, De Pretter V, de Brandt E, Verbeke K, Swings J & Huys G (2006) Molecular monitoring of the fecal microbiota of healthy human subjects during administration of lactulose and Saccharomyces boulardii. Appl Environ Microbiol 72: 5990-5997.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 5990-5997
    • Vanhoutte, T.1    De Pretter, V.2    de Brandt, E.3    Verbeke, K.4    Swings, J.5    Huys, G.6
  • 62
    • 0000379811 scopus 로고    scopus 로고
    • TNO's in vitro large intestinal model: an excellent screening tool for functional food and pharmaceutical research
    • Venema K, van Nuenen HMC, Smeets-Peeters M, Minekus M & Havenaar R (2000) TNO's in vitro large intestinal model: an excellent screening tool for functional food and pharmaceutical research. Ernährung/Nutrition 24: 558-564.
    • (2000) Ernährung/Nutrition , vol.24 , pp. 558-564
    • Venema, K.1    van Nuenen, H.M.C.2    Smeets-Peeters, M.3    Minekus, M.4    Havenaar, R.5
  • 64
    • 0033989325 scopus 로고    scopus 로고
    • Detection and identification of gastrointestinal Lactobacillus species by using denaturing gradient gel electrophoresis and species-specific PCR primers
    • Walter J, Tannock GW, Tilsala-Timisjarvi A, Rodtong S, Loach DM, Munro K & Alatossava T (2000) Detection and identification of gastrointestinal Lactobacillus species by using denaturing gradient gel electrophoresis and species-specific PCR primers. Appl Environ Microbiol 66: 297-303.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 297-303
    • Walter, J.1    Tannock, G.W.2    Tilsala-Timisjarvi, A.3    Rodtong, S.4    Loach, D.M.5    Munro, K.6    Alatossava, T.7
  • 65
    • 0035374627 scopus 로고    scopus 로고
    • Detection of Lactobacillus, Pediococcus, Leuconostoc, and Weissella species in human feces by using group-specific PCR primers and denaturing gradient gel electrophoresis
    • Walter J, Hertel C, Tannock GW, Lis CM, Munro K & Hammes WP (2001) Detection of Lactobacillus, Pediococcus, Leuconostoc, and Weissella species in human feces by using group-specific PCR primers and denaturing gradient gel electrophoresis. Appl Environ Microbiol 67: 2578-2585.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 2578-2585
    • Walter, J.1    Hertel, C.2    Tannock, G.W.3    Lis, C.M.4    Munro, K.5    Hammes, W.P.6
  • 66
    • 70349570169 scopus 로고    scopus 로고
    • A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and symbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer
    • Worthley DL, Le Leu RK, Whitehall VL et al. (2009) A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and symbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. Am J Clin Nutr 80: 578-586.
    • (2009) Am J Clin Nutr , vol.80 , pp. 578-586
    • Worthley, D.L.1    Le Leu, R.K.2    Whitehall, V.L.3
  • 67
    • 0142026205 scopus 로고    scopus 로고
    • Inaugural article: honor thy symbionts
    • Xu J & Gordon JI (2003) Inaugural article: honor thy symbionts. P Natl Acad Sci USA 100: 10452-10459.
    • (2003) P Natl Acad Sci USA , vol.100 , pp. 10452-10459
    • Xu, J.1    Gordon, J.I.2
  • 68
    • 2442510059 scopus 로고    scopus 로고
    • Improved extraction of PCR-quality community DNA from digesta and fecal samples
    • Yu Z & Morrison M (2004) Improved extraction of PCR-quality community DNA from digesta and fecal samples. Biotechniques 36: 808-812.
    • (2004) Biotechniques , vol.36 , pp. 808-812
    • Yu, Z.1    Morrison, M.2
  • 69
    • 0031684010 scopus 로고    scopus 로고
    • Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria
    • Zoetendal EG, Akkermans ADI & de Vos WM (1998) Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 64: 3854-3859.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 3854-3859
    • Zoetendal, E.G.1    Akkermans, A.D.I.2    de Vos, W.M.3


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