Microbiology: Diversity of the human intestinal microbial flora

Science

Volumn 308, Issue 5728, 2005, Pages 1635-1638

  Eckburg, Paul B ^a   Bik, Elisabeth M ^a   Bernstein, Charles N ^b   Purdom, Elizabeth ^c   Dethlefsen, Les ^a   Sargent, Michael ^b   Gill, Steven R ^d   Nelson, Karen E ^d   Relman, David A ^a,e  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c STANFORD UNIVERSITY   (United States)

^d J CRAIG VENTER INSTITUTE   (United States)

^e VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOLOGICAL ORGANS; DISEASES; ECOSYSTEMS; GENES; HEALTH; IMMUNOLOGY; MICROORGANISMS; RNA;

EPITHELIAL DEVELOPMENT; HUMAN ENDOGENOUS INTESTINAL MICROFLORA; MUCOSA COMMUNITY COMPOSITION;

MICROBIOLOGY;

MICROBIAL COMMUNITY;

ADULT; ARTICLE; CASE REPORT; COLON MUCOSA; FECES ANALYSIS; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; INTESTINE FLORA; MICROBIAL DIVERSITY; NORMAL HUMAN; PRIORITY JOURNAL; RNA GENE; BACTERIAL GENE; BACTERIUM; BACTEROIDETES; BIODIVERSITY; CLASSIFICATION; COLON; ECOSYSTEM; FECES; GENE; GENETIC VARIABILITY; GENETICS; INTESTINE MUCOSA; ISOLATION AND PURIFICATION; METHANOBREVIBACTER; MICROBIOLOGY; MIDDLE AGED; MOLECULAR GENETICS; PHYLOGENY; POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); PROKARYOTA;

RIBOSOME DNA; RNA 16S;

ADULT; BACTERIA; BACTEROIDETES; BIODIVERSITY; COLON; DNA, RIBOSOMAL; ECOSYSTEM; FECES; GENES, ARCHAEAL; GENES, BACTERIAL; GENES, RRNA; HUMANS; INTESTINAL MUCOSA; METHANOBREVIBACTER; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PHYLOGENY; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S; VARIATION (GENETICS);

EID: 20544444045     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1110591     Document Type: Article

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25. We thank B. Bohannan, M. B. Omary, and S. Holmes (Stanford University) for helpful comments on the manuscript. This research was supported by grants from the NIH (no. AI51259) and Ellison Medical Foundation (D.A.R.), Canadian Institutes of Health Research and Crohn's and Colitis Foundation of Canada (C.N.B., M.S.), National Science Foundation (E.P.), and Defense Advanced Research Projects Agency (S.R.G., K.E.N.). Representatives of novel phylotypes (AY916135 to AY916390) and all other sequences (AY974810 to AY986384) were deposited in GenBank.