Farnesol production in Escherichia coli through the construction of a farnesol biosynthesis pathway – application of PgpB and YbjG phosphatases

Biotechnology Journal

Volumn 11, Issue 10, 2016, Pages 1291-1297

  Wang, Chonglong ^a,b   Park, Ju Eon ^a   Choi, Eui Sung ^c   Kim, Seon Won ^a  

^a Gyeongsang National University   (South Korea)

^b SOOCHOW UNIVERSITY   (China)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Escherichia coli; Farnesol; PgpB; Phosphatase; YbjG

Indexed keywords

BIOCHEMISTRY; ESCHERICHIA COLI; HYDROLYSIS;

BIOSYNTHESIS PATHWAYS; FARNESOL; FARNESYL DIPHOSPHATE; MEVALONATE PATHWAY; PGPB; RECOMBINANT E. COLI; SYNTHESIS PATHWAYS; YBJG;

PHOSPHATASES;

FARNESOL; FARNESYL DIPHOSPHATE; GERANYLTRANSFERASE; HISTIDINE; MEMBRANE PROTEIN; MEVALONIC ACID; PHOSPHATASE; PROTEIN ISPA; PROTEIN PGPB; PROTEIN YBJG; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; ESCHERICHIA COLI; GENE INACTIVATION; GENE OVEREXPRESSION; HYDROLYSIS; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS;

EID: 84989898744     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201600250     Document Type: Article

References (25)

1. Peralta-Yahya, P. P., Zhang, F., del Cardayre, S. B., Keasling, J. D., Microbial engineering for the production of advanced biofuels. Nature 2012, 488, 320–328.
2. Keasling, J. D., Manufacturing molecules through metabolic engineering. Science 2010, 330, 1355–1358.
3. Zhang, K., Sawaya, M. R., Eisenberg, D. S., Liao, J. C., Expanding metabolism for biosynthesis of nonnatural alcohols. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 20653–20658.
4. Withers, S. T., Gottlieb, S. S., Lieu, B., Newman, J. D. et al., Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. Appl. Environ. Microbiol. 2007, 73, 6277–6283.
5. Chou, H. H., Keasling, J. D., Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. Appl. Environ. Microbiol. 2012, 78, 7849–7855.
6. Wang, C., Kim, J. Y., Choi, E. S., Kim, S. W., Microbial production of farnesol (FOH): Current states and beyond. Process Biochem. 2011, 46, 1221–1229.
7. Wang, C., Yoon, S. H., Shah, A. A., Chung, Y. R. et al., Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. Biotechnol. Bioeng. 2010, 107, 421–429.
8. Ohto, C., Muramatsu, M., Obata, S., Sakuradani, E. et al., Overexpression of the gene encoding HMG-CoA reductase in Saccharomycescerevisiae for production of prenyl alcohols. Appl Microbiol. Biotechnol. 2009, 82, 837–845.
9. Dahl, R. H., Zhang, F., Alonso-Gutierrez, J., Baidoo, E. et al., Engineering dynamic pathway regulation using stress-response promoters. Nat. Biotechnol. 2013, 31, 1039–1046.
10. Yoon, S. H., Lee, S. H., Das, A., Ryu, H. K. et al., Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli. J. Biotechnol. 2009, 140, 218–226.
11. Bickford, J. S., Nick, H. S., Conservation of the PTEN catalytic motif in the bacterial undecaprenyl pyrophosphate phosphatase, BacA/UppP. Microbiology 2013, 159, 2444–2455.
12. Tatar, L. D., Marolda, C. L., Polischuk, A. N., van Leeuwen, D. et al., An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling. Microbiology 2007, 153, 2518–2529.
13. Touze, T., Blanot, D., Mengin-Lecreulx, D., Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase. J. Biol. Chem. 2008, 283, 16573–16583.
14. El Ghachi, M., Derbise, A., Bouhss, A., Mengin-Lecreulx, D., Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. J. Biol. Chem. 2005, 280, 18689–18695.
15. Icho, T., Membrane-bound phosphatases in Escherichia coli: Sequence of the pgpB gene and dual subcellular localization of the pgpB product. J. Bacteriol. 1988, 170, 5117–5124.
16. Funk, C. R., Zimniak, L., Dowhan, W., The pgpA and pgpB genes of Escherichia coli are not essential: Evidence for a third phosphatidylglycerophosphate phosphatase. J. Bacteriol. 1992, 174, 205–213.
17. Icho, T., Membrane-bound phosphatases in Escherichia coli: Sequence of the pgpA gene. J. Bacteriol. 1988, 170, 5110–5116.
18. Lu, Y. H., Guan, Z., Zhao, J., Raetz, C. R., Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli. J. Biol. Chem. 2011, 286, 5506–5518.
19. Stukey, J., Carman, G. M., Identification of a novel phosphatase sequence motif. Protein Sci. 1997, 6, 469–472.
20. Ishikawa, K., Mihara, Y., Gondoh, K., Suzuki, E. et al., X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate. EMBO J. 2000, 19, 2412–2423.
21. Fan, J., Jiang, D., Zhao, Y., Liu, J. et al., Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B. Proc. Natl. Acad. Sci. USA 2014, 111, 7636–7640.
22. Marolda, C. L., Vicarioli, J., Valvano, M. A., Wzx proteins involved in biosynthesis of O antigen function in association with the first sugar of the O-specific lipopolysaccharide subunit. Microbiology 2004, 150, 4095–4105.
23. Alaimo, C., Catrein, I., Morf, L., Marolda, C. L. et al., Two distinct but interchangeable mechanisms for flipping of lipid-linked oligosaccharides. EMBO J. 2006, 25, 967–976.
24. Bick, J. A., Lange, B. M., Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: Unidirectional transport of intermediates across the chloroplast envelope membrane. Arch. Biochem. Biophys. 2003, 415, 146–154.
25. Laule, O., Furholz, A., Chang, H. S., Zhu, T. et al., Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 2003, 100, 6866–6871.